Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

  • Multiple doses of stem cells maintain urethral function in a model of neuromuscular injury resulting in stress urinary incontinence 
    Janssen, Kristine; Lin, Dan Li; Hanzlicek, Brett; Deng, Kangli; Balog, Brian M; van der Vaart, Carl H; Damaser, Margot S (American Physiological Society, 2019-10-01)
    Stress urinary incontinence (SUI) is more prevalent among women who deliver vaginally than women who have had a cesarean section, suggesting that tissue repair after vaginal delivery is insufficient. A single dose of ...
  • Underestimation of pelvic organ prolapse in the supine straining position, based on magnetic resonance imaging findings 
    Grob, Anique T.M.; Heuvel, Judith olde; Futterer, Jurgen J.; Massop, Diana; Veenstra van Nieuwenhoven, Angelique L.; Simonis, Frank F.J.; van der Vaart, Carl H. (Springer Nature, 2019-11)
    OBJECTIVE: Pelvic organ prolapse (POP) is clinically diagnosed in the supine position, where the effect of gravity is simulated by having the patients put strain on their pelvic floor. The objective of this study was to ...
  • Gonadotrophins versus clomiphene citrate with or without IUI in women with normogonadotropic anovulation and clomiphene failure: a cost-effectiveness analysis 
    Bordewijk, E. M.; Weiss, N. S.; Nahuis, M. J.; Bayram, N.; Van Hooff, M. H.A.; Boks, D. E.S.; Perquin, D. A.M.; Janssen, C. A.H.; Van Golde, R. J.T.; Lambalk, C. B.; Goddijn, M.; Hompes, P. G.; Van Der Veen, F.; Mol, B. W.J.; Van Wely, M.; Weiss, N. S.; Bordewijk, E. M.; Nahuis, M. J.; Smeenk, J. M.J.; Hoek, A.; Broekmans, F. J.M.; Fleischer, K.; De Bruin, J. P.; Kaaijk, E. M.; Laven, J. S.E.; Hendriks, D. J.; Gerards, M. H.; Bourdrez, P.; Gianotten, J.; Koks, C.; Bayram, N.; Van Hooff, M.; Boks, D. E.S.; Perquin, D. A.M.; Janssen, C. A.H.; Van Golde, R. J.T.; Kwee, J.; Lambeek, A. F.; Van Unnik, A. F.; Vrouenraets, F. P.J.; Cohlen, B. J.; Van De Laar-Van Asseldonk, T. A.M.; Nap, A. W.; Van Rijn-Van Weert, J. M.; Vollebergh, J. H.A.; Klijn, N. F.; Rijnsaardt-Lukassen, H. G.M.; Sluijmer, A. V.; Lambalk, C. B.; Goddijn, M.; Hompes, P. G.; Van Der Veen, F.; Mol, B. W.J.; Van Wely, M. (Oxford University Press, 2019-02-01)
    STUDY QUESTION Are six cycles of ovulation induction with gonadotrophins more cost-effective than six cycles of ovulation induction with clomiphene citrate (CC) with or without IUI in normogonadotropic anovulatory women ...
  • Evaluation of the Elecsys ® anti-Müllerian hormone assay for the prediction of hyper-response to controlled ovarian stimulation with a gonadotrophin-releasing hormone antagonist protocol. 
    Anckaert, Ellen; Denk, Barbara; He, Ying; Torrance, Helen L.; Broekmans, Frank; Hund, Martin (Elsevier Ireland Ltd, 2019-05-01)
    OBJECTIVE: This non-interventional study aimed to validate a pre-specified anti-Müllerian hormone (AMH) cut-off of 15 pmol/L (2.10 ng/mL) for the prediction of hyper-response to controlled ovarian stimulation (COS) using ...
  • The vaginal microbiome as a predictor for outcome of in vitro fertilization with or without intracytoplasmic sperm injection: A prospective study 
    Koedooder, R.; Singer, M.; Schoenmakers, S.; Savelkoul, P. H.M.; Morré, S. A.; De Jonge, J. D.; Poort, L.; Cuypers, W. J.S.S.; Beckers, N. G.M.; Broekmans, F. J.M.; Cohlen, B. J.; Den Hartog, J. E.; Fleischer, K.; Lambalk, C. B.; Smeenk, J. M.J.S.; Budding, A. E.; Laven, J. S.E. (Oxford University Press, 2019-06-04)
    STUDY QUESTION: Is the presence or absence of certain vaginal bacteria associated with failure or success to become pregnant after an in vitro fertilization (IVF) or IVF with intracytoplasmic sperm injection (IVF-ICSI) ...
  • Growth, health, and motor development of 5-year-old children born after preimplantation genetic diagnosis 
    Heijligers, Malou; Peeters, Andrea; van Montfoort, Aafke; Nijsten, Joyce; Janssen, Etienne; Gunnewiek, Femke Klein; de Rooy, Rick; van Golde, Ron; Coonen, Edith; Meijer-Hoogeveen, Madelon; Broekmans, Frank; van der Hoeven, Mark; Arens, Yvonne; de Die-Smulders, Christine (Elsevier, 2019-06-01)
    Objective: To evaluate the growth, health, and motor development of children born after preimplantation genetic diagnosis (PGD). Design: Observational cohort study and comparison of 5-year-old children born after PGD to ...
  • Individualization of FSH doses in assisted reproduction: Facts and fiction 
    Broekmans, Frank J. (Frontiers Media S. A., 2019-04-26)
    The art of ovarian stimulation for IVF/ICSI treatment using exogenous FSH should be balanced against the relative contribution of other steps of the ART process such as the IVF-lab-phase and the Embryo-Transfer. The aim ...
  • Risk factors for in-hospital mortality in patients with dementia 
    Golüke, Nienke M S; van de Vorst, Irene E; Vaartjes, Ilonca H; Geerlings, Mirjam I; de Jonghe, Annemarieke; Bots, Michiel L; Koek, Huiberdina L (Elsevier Ireland Ltd, 2019-11)
    OBJECTIVE: To examine the in-hospital mortality rate, and its risk factors, for patients with dementia admitted to hospital. STUDY DESIGN: We constructed an observational cohort study through data linkage of three Dutch ...
  • Factors that influence the intended intensity of diabetes care in a person-centred setting 
    van Vugt, H. A.; Heijmans, M. J.W.M.; de Koning, E. J.P.; Rutten, G. E.H.M. (Wiley-Blackwell, 2020-07)
    Aims: To assess the intended intensity of Type 2 diabetes care and the factors associated with that intensity of care after the annual monitoring visit in which a new person-centred diabetes consultation model including ...
  • Pharmacokinetics and short-term safety of the selective NOS inhibitor 2-iminobiotin in asphyxiated neonates treated with therapeutic hypothermia 
    Favié, Laurent M A; Peeters-Scholte, Cacha M P C D; Bakker, Anouk; Tjabbes, Huibert; Egberts, Toine C G; van Bel, Frank; Rademaker, Carin M A; Vis, Peter; Groenendaal, Floris (Lippincott Williams & Wilkins, 2020-03-01)
    BACKGROUND: Neonatal encephalopathy following perinatal asphyxia is a leading cause for neonatal death and disability, despite treatment with therapeutic hypothermia. 2-Iminobiotin is a promising neuroprotective agent ...
  • Rotavirus-Induced Neonatal Epileptic Encephalopathy-A Disease Spectrum Illustrated by Monochorionic Twins 
    Hopmans, Esther M; van der Heide, Astrid; Chung, Pui Khi; Brinkman, Daniëlle; Feltkamp, Mariet C W; van Dijk, J Gert; Steggerda, Sylke J; Niks, Erik H (Georg Thieme Verlag, 2020-02)
    Rotavirus has been associated with neonatal seizures and specific white matter magnetic resonance imaging (MRI) abnormalities. We describe monochorionic twins who not only tested positive for rotavirus with these white ...
  • Repeated oral glucose tolerance tests in women at risk for gestational diabetes mellitus 
    de Wit, L.; Bos, D. M.; van Rossum, A. P.; van Rijn, B. B.; Boers, K. E. (Elsevier Ireland Ltd, 2019-11-01)
    Objective: Pregnant women with a negative oral glucose tolerance test (OGTT) between 24–28 weeks as part of risk-based screening for gestational diabetes mellitus (GDM) may develop clinical signs or symptoms suggestive for ...
  • Defining Functional Therapy in Research Involving Children with Cerebral Palsy: A Systematic Review 
    Geijen, Mellanie; Ketelaar, Marjolijn; Sakzewski, Leanne; Palisano, Robert; Rameckers, Eugene (Informa Healthcare, 2020)
    Aim: To review definitions and elements of interventions in studies, which used the word "functional" to describe their intervention for children with cerebral palsy (CP), and to determine whether definitions and elements ...
  • Synapse Pathology in Schizophrenia: A Meta-analysis of Postsynaptic Elements in Postmortem Brain Studies 
    Berdenis van Berlekom, Amber; Muflihah, Cita H; Snijders, Gijsje J L J; MacGillavry, Harold D; Middeldorp, Jinte; Hol, Elly M; Kahn, René S; de Witte, Lot D (Oxford University Press, 2020-02-26)
    Changed synapse density has been suggested to be involved in the altered brain connectivity underlying schizophrenia (SCZ) pathology. However, postmortem studies addressing this topic are heterogeneous and it is not known ...
  • Towards Precision Medicine in Psychosis: Benefits and Challenges of Multimodal Multicenter Studies-PSYSCAN: Translating Neuroimaging Findings From Research into Clinical Practice 
    Tognin, Stefania; van Hell, Hendrika H.; Merritt, Kate; Winter-van Rossum, Inge; Bossong, Matthijs G.; Kempton, Matthew J.; Modinos, Gemma; Fusar-Poli, Paolo; Mechelli, Andrea; Dazzan, Paola; Maat, Arija; de Haan, Lieuwe; Crespo-Facorro, Benedicto; Glenthøj, Birte; Lawrie, Stephen M.; McDonald, Colm; Gruber, Oliver; van Amelsvoort, Therese; Arango, Celso; Kircher, Tilo; Nelson, Barnaby; Galderisi, Silvana; Bressan, Rodrigo; Kwon, Jun S.; Weiser, Mark; Mizrahi, Romina; Sachs, Gabriele; Maatz, Anke; Kahn, René; McGuire, Phillip; PSYSCAN Consortium (Oxford University Press, 2020-03-01)
    In the last 2 decades, several neuroimaging studies investigated brain abnormalities associated with the early stages of psychosis in the hope that these could aid the prediction of onset and clinical outcome. Despite ...
  • Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling 
    Undiagnosed Diseases Network (Elsevier, 2020-01-15)
    BACKGROUND: The X-chromosome gene USP9X encodes a deubiquitylating enzyme that has been associated with neurodevelopmental disorders primarily in female subjects. USP9X escapes X inactivation, and in female subjects de ...
  • De Novo and Inherited Pathogenic Variants in KDM3B Cause Intellectual Disability, Short Stature, and Facial Dysmorphism 
    Diets, Illja J.; van der Donk, Roos; Baltrunaite, Kristina; Waanders, Esmé; Reijnders, Margot R.F.; Dingemans, Alexander J.M.; Pfundt, Rolph; Vulto-van Silfhout, Anneke T.; Wiel, Laurens; Gilissen, Christian; Thevenon, Julien; Perrin, Laurence; Afenjar, Alexandra; Nava, Caroline; Keren, Boris; Bartz, Sarah; Peri, Bethany; Beunders, Gea; Verbeek, Nienke; van Gassen, Koen; Thiffault, Isabelle; Cadieux-Dion, Maxime; Huerta-Saenz, Lina; Wagner, Matias; Konstantopoulou, Vassiliki; Vodopiutz, Julia; Griese, Matthias; Boel, Annekatrien; Callewaert, Bert; Brunner, Han G.; Kleefstra, Tjitske; Hoogerbrugge, Nicoline; de Vries, Bert B.A.; Hwa, Vivian; Dauber, Andrew; Hehir-Kwa, Jayne Y.; Kuiper, Roland P.; Jongmans, Marjolijn C.J. (Cell Press, 2019-04-04)
    By using exome sequencing and a gene matching approach, we identified de novo and inherited pathogenic variants in KDM3B in 14 unrelated individuals and three affected parents with varying degrees of intellectual disability ...
  • Healthy lifestyle and the risk of pancreatic cancer in the EPIC study 
    Naudin, Sabine; Viallon, Vivian; Hashim, Dana; Freisling, Heinz; Jenab, Mazda; Weiderpass, Elisabete; Perrier, Flavie; McKenzie, Fiona; Bueno-de-Mesquita, H Bas; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C; Overvad, Kim; Mancini, Francesca R; Rebours, Vinciane; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kaaks, Rudolf; Bergmann, Manuela; Boeing, Heiner; Peppa, Eleni; Karakatsani, Anna; Trichopoulou, Antonia; Pala, Valeria; Masala, Giovana; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; May, Anne M; van Gils, Carla H; Rylander, Charlotta; Borch, Kristin Benjaminsen; Chirlaque López, María Dolores; Sánchez, Maria-Jose; Ardanaz, Eva; Quirós, José Ramón; Amiano Exezarreta, Pilar; Sund, Malin; Drake, Isabel; Regnér, Sara; Travis, Ruth C; Wareham, Nick; Aune, Dagfinn; Riboli, Elio; Gunter, Marc J; Duell, Eric J; Brennan, Paul; Ferrari, Pietro (Springer Netherlands, 2020-10-01)
    Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early detection and effective treatment. Modifiable factors may offer pathways for primary prevention. In this study, the association ...
  • Loss-of-function variants in myocardin cause congenital megabladder in humans and mice 
    Houweling, Arjan C; Beaman, Glenda M; Postma, Alex V; Gainous, T Blair; Lichtenbelt, Klaske D; Brancati, Francesco; Lopes, Filipa M; van der Made, Ingeborg; Polstra, Abeltje M; Robinson, Michael L; Wright, Kevin D; Ellingford, Jamie M; Jackson, Ashley R; Overwater, Eline; Genesio, Rita; Romano, Silvio; Camerota, Letizia; D'Angelo, Emanuela; Meijers-Heijboer, Elizabeth J; Christoffels, Vincent M; McHugh, Kirk M; Black, Brian L; Newman, William G; Woolf, Adrian S; Creemers, Esther E (American Society for Clinical Investigation, 2019-12-02)
    Myocardin (MYOCD) is the founding member of a class of transcriptional coactivators that bind the serum-response factor to activate gene expression programs critical in smooth muscle (SM) and cardiac muscle development. ...
  • Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin 
    van den Bogaard, Ellen H J; van Geel, Michel; van Vlijmen-Willems, Ivonne M J J; Jansen, Patrick A M; Peppelman, Malou; van Erp, Piet E J; Atalay, Selma; Venselaar, Hanka; Simon, Marleen E H; Joosten, Marieke; Schalkwijk, Joost; Zeeuwen, Patrick L J M (Lippincott Williams & Wilkins, 2019-07)
    PURPOSE: We aimed to assess the biological and clinical significance of the human cysteine protease inhibitor cystatin M/E, encoded by the CTS6 gene, in diseases of human hair and skin. METHODS: Exome and Sanger sequencing ...