Since the beginning of the 20th century the constant increase of the cancer incidence in the developed world has led to extensive research to improve the effectiveness of treatments, including chemotherapy. While chemotherapy ...

Worldwide, 871 million people suffers from hypertension (an office systolic blood pressure (BP) of ≥140 and/or diastolic BP ≥90 mmHg). Only 35% of the patients known with hypertension reaches guideline targets. The remaining ...

Blood transfusion is an important medical treatment for many and diverse patients groups, saving lives but sometimes also causing adverse transfusion reactions in transfusion recipients. For this reason blood use should ...

Female reproductive ageing is a complex trait mostly explained by a combination of genetic and non-genetic factors. It compromises the decline in the number of oocytes (quantity) and the decrease of oocyte quality. It has ...

In this thesis the activation state of blood eosinophils and neutrophils was discovered to contribute significantly to the diagnostic accuracy of a quick and low-invasive test for eosinophilia asthma. In patients with ...

Neurogenesis and gliogenesis are processes that occur during development of the CNS as well as after insult of the nervous system. These tightly regulated processes take place in specialized niches during embryogenesis and ...

The patient safety movement was triggered by publications showing that modern health care is more unsafe than road travel and that more patients are killed annually by avoidable adverse events than by breast cancer [1]. ...