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Now showing items 28881-28900 of 40729

Characterizing Adult Sleep Behavior Over 20 Years-The Population-Based Doetinchem Cohort Study

Zomers, Margot L; Hulsegge, Gerben; van Oostrom, Sandra H; Proper, Karin I.; Verschuren, W M Monique; Picavet, H. Susan J (Hindawi Limited, 2017-07-01)

Study Objectives: To describe sleep duration patterns of adults over a 20-year period; to compare sociodemographic, lifestyle, and health characteristics across these patterns; and to relate the patterns to sleep quality. ...
Linee guida europee 2016 sulla prevenzione delle malattie cardiovascolari nella pratica clinica. Sesta Task Force congiunta della Società Europea di Cardiologia e di altre Società sulla Prevenzione delle Malattie Cardiovascolari nella Pratica Clinica (costituita da rappresentanti di 10 società e da esperti invitati). Redatte con il contributo straordinario dell’Associazione Europea per la Prevenzione e Riabilitazione Cardiovascolare (EACPR)

Piepoli, Massimo F.; Hoes, Arno W; Agewall, Stefan; Albus, Christian; Brotons, Carlos; Catapano, Alberico L.; Cooney, Marie Therese; Corrà, Ugo; Cosyns, Bernard; Deaton, Christi; Graham, Ian; Hall, Michael Stephen; Hobbs, F D Richard; Løchen, Maja Lisa; Löllgen, Herbert; Marques-Vidal, Pedro; Perk, Joep; Prescott, Eva; Redon, Josep; Richter, Dimitrios J.; Sattar, Naveed; Smulders, Yvo; Tiberi, Monica; van der Worp, H Bart; van Dis, Ineke; Verschuren, W M Monique (CEPI s.r.l., 2017-07-18)
A four-domain approach of frailty explored in the Doetinchem Cohort Study

van Oostrom, Sandra H; van der A, Daphne L.; Rietman, M Liset; Picavet, H. Susan J; Lette, Manon; Verschuren, W M Monique; de Bruin, Simone R; Spijkerman, Annemieke M. W. (BioMed Central, 2017-08-30)

Background: Accumulation of problems in physical, psychological, cognitive, or social functioning is characteristic for frail individuals. Using a four-domain approach of frailty, this study explored how sociodemographic ...
Consumption of whole grains, fruit and vegetables is not associated with indices of renal function in the population-based longitudinal Doetinchem study

Herber-Gast, Gerrie Cor M; Boersma, Marijke; Verschuren, W. M.Monique; Stehouwer, Coen D. A.; Gansevoort, Ron T.; Bakker, Stephan J. L.; Spijkerman, Annemieke M. W. (Cambridge University Press, 2017-09-14)

Emerging evidence suggests that diet and renal function are related. Little is known, however, about the association of consumption of whole grains, fruit and vegetables with urinary albumin:creatinine ratio (ACR) and ...
Leukocytic toll-like receptor 2 deficiency preserves cardiac function and reduces fibrosis in sustained pressure overload

Wang, Jiong-Wei; Fontes, Magda S.C.; Wang, Xiaoyuan; Chong, Suet Yen; Kessler, Elise L.; Zhang, Ya-Nan; De Haan, Judith J.; Arslan, Fatih; De Jager, Saskia C.A.; Timmers, Leo; Van Veen, Toon A.B.; Lam, Carolyn S P; de Kleijn, Dominique P V (Nature Publishing Group, 2017-12-01)

An involement of Toll-like receptor 2 (TLR2) has been established in cardiac dysfunction after acute myocardial infarction; however, its role in chronic pressure overload is unclear. We sought to evaluate the role of TLR2 ...
Maintenance treatment with capecitabine and bevacizumab versus observation in metastatic colorectal cancer: Updated results and molecular subgroup analyses of the phase 3 CAIRO3 study

Goey, K. K.H.; Elias, S. G.; van Tinteren, H.; Laclé, M. M.; Willems, S. M.; Offerhaus, G. J.A.; de Leng, W. W.J.; Strengman, E.; ten Tije, Albert J; Creemers, Geert Jan M; van der Velden, A.; de Jongh, Felix E; Erdkamp, Frans L G; Tanis, B C; Punt, C. J A; Koopman, Miriam (Oxford University Press, 2017-09)

Background: The phase 3 CAIRO3 study showed that capecitabine plus bevacizumab (CAP-B) maintenance treatment after six cycles capecitabine, oxaliplatin, and bevacizumab (CAPOX-B) in metastatic colorectal cancer (mCRC) ...
Cost-effectiveness of human papillomavirus vaccination in Germany

Damm, Oliver; Horn, Johannes; Mikolajczyk, Rafael T; Kretzschmar, Mirjam E E; Kaufmann, Andreas M; Deleré, Yvonne; Ultsch, Bernhard; Wichmann, Ole; Krämer, Alexander; Greiner, Wolfgang (BioMed Central, 2017)

BACKGROUND: The aim of this study was to assess the cost-effectiveness of human papillomavirus (HPV) vaccination in addition to the current cervical cancer screening programme in Germany using a dynamic transmission model. ...
Sudden Death Due to Coronary Artery Lesions Long-term After the Arterial Switch Operation: A Systematic Review.

van Wijk, Sebastiaan W.H.; van der Stelt, Femke; ter Heide, Henriëtte; Schoof, Paul H.; Doevendans, Pieter A.F.M.; Meijboom, Folkert J.; Breur, Johannes M.P.J. (Elsevier, 2017-09-01)

Background The arterial switch operation (ASO) is the preferred procedure for children with dextrotransposition of the great arteries or Taussig-Bing anomaly. Short- as well as long-term outcome of ASO are excellent, but ...
Concise review: Developing best-practice models for the therapeutic use of extracellular vesicles

Reiner, Agnes T.; Witwer, Kenneth W.; Van Balkom, Bas W.M.; De Beer, Joel; Brodie, Chaya; Corteling, Randolph L.; Gabrielsson, Susanne; Gimona, Mario; Ibrahim, Ahmed G.; De Kleijn, Dominique; Lai, Charles P.; Tvall, Jan Lo; Del Portillo, Hernando A; Reischl, Ilona G; Riazifar, Milad; Salomon, Carlos; Tahara, Hidetoshi; Toh, Wei Seong; Wauben, Marca H M; Yang, Vicky K.; Yang, Yijun; Yeo, Ronne Wee Yeh; Yin, Hang; Giebel, Bernd; Rohde, Eva; Lim, Sai Kiang (Oxford University Press, 2017-08-01)

Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell-related approaches, has underlined the need for standardization and coordination of ...
Disturbed Desmoglein-2 in the intercalated disc of pediatric patients with dilated cardiomyopathy

Kessler, Elise L.; Nikkels, Peter GJ; van Veen, Toon AB (W.B. Saunders, 2017-09-01)

Dilated cardiomyopathy (DCM) leads to disturbed contraction and force transduction, and is associated with substantial mortality in all age groups. Involvement of a disrupted composition of the intercalated disc (ID) has ...
Dynamics of recent thymic emigrants in young adult mice

van Hoeven, Vera; Drylewicz, Julia; Westera, Liset; den Braber, Ineke; Mugwagwa, Tendai; Tesselaar, Kiki; Borghans, José A.M.; de Boer, Rob J. (Frontiers Media S. A., 2017-08-07)

The peripheral naive T-cell pool is generally thought to consist of a subpopulation of recent thymic emigrants (RTEs) and a subpopulation of mature naive (MN) T cells with different dynamics. Thymus transplantation and ...
GABAergic Mechanisms in Schizophrenia: Linking Postmortem and In Vivo Studies

de Jonge, Jeroen C; Vinkers, Christiaan H; Hulshoff Pol, Hilleke E; Marsman, Anouk (Frontiers Research Foundation, 2017)

Schizophrenia is a psychiatric disorder characterized by hallucinations, delusions, disorganized thinking, and impairments in cognitive functioning. Evidence from postmortem studies suggests that alterations in cortical ...
Outcome reporting bias in randomized-controlled trials investigating antipsychotic drugs

Lancee, M; Lemmens, C M C; Kahn, R S; Vinkers, C H; Luykx, J J (Nature Publishing Group, 2017-09-12)

Recent literature hints that outcomes of clinical trials in medicine are selectively reported. If applicable to psychotic disorders, such bias would jeopardize the reliability of randomized clinical trials (RCTs) investigating ...
Irradiance levels of phototherapy devices: A national study in Dutch neonatal intensive care units

Hulzebos, Christian V.; Van't Klooster, S. J.; Krummel-Lorenz, B; Vreman, Hendrik J.; Dijk, Peter H.; Benders, M. J.N.L.; Buijs, J.; Dudink, J.; Van Imhoff, Deirdre E.; Laarman, Céleste R.; Liem, Kian D.; van Lingen, R. A.; Lopriore, E.; Mulder, A. L M; Toledo-Eppinga, L.; BARTrial Study Group (Springer Nature, 2017-07-01)

Objective: The objective of this study is to determine whether irradiance levels of phototherapy (PT) devices in Dutch neonatal intensive care units (NICUs) increased between 2008 and 2013. Study Design: Irradiance of all ...
Myeloperoxidase can differentiate between sepsis and non-infectious SIRS and predicts mortality in intensive care patients with SIRS

Schrijver, Irene T; Kemperman, Hans; Roest, Mark; Kesecioglu, Jozef; de Lange, Dylan W (Springer Science + Business Media, 2017-09-15)

BACKGROUND: Systemic inflammatory response syndrome (SIRS) is a clinical syndrome following inflammation. Clinically, it is difficult to distinguish SIRS following an infection, i.e., sepsis, from non-infectious SIRS. ...
Response to the letters to the editor from Van der voort et al. and Vodovar and Mégarbane : Could extracorporeal albumin dialysis be considered as an adjunct therapy in calcium channel blocker overdose?

Rietjens, S. J.; Donker, D. W.; de Lange, D. W. (Van Zuiden Communications BV, 2016-07)
Factors Associated with Mortality in Low-Risk Pediatric Critical Care Patients in the Netherlands

Verlaat, Carin W.; Visser, Idse H.; Wubben, Nina; Hazelzet, Jan A.; Lemson, Joris; van Waardenburg, Dick A; Van Der Heide, Douwe; Van Dam, Nicolette A.; Jansen, Nicolaas J.; Van Heerde, Mark; van der Starre, Cynthia; Van Asperen, Roelie; Kneyber, Martin; van Woensel, Job B M; Van Den Boogaard, Mark; van der Hoeven, Johannes G. (Lippincott Williams & Wilkins, 2017-04-01)

Objective: To determine differences between survivors and nonsurvivors and factors associated with mortality in pediatric intensive care patients with low risk of mortality. Design: Retrospective cohort study. Setting: ...
Citrate versus heparin anticoagulation in continuous renal replacement therapy in small children

Raymakers-Janssen, Paulien A M; Lilien, Marc; van Kessel, Ingrid A.; Veldhoen, Esther S.; Wösten-van Asperen, Roelie M.; van Gestel, Josephus P.J. (Springer-Verlag, 2017-10-01)

Background: Citrate is preferred over heparin as an anticoagulant in adult continuous renal replacement therapy (CRRT). However, its potential adverse effects and data on use in CRRT in infants and toddlers is limited. We ...
A cost-effectiveness analysis of screening for intracranial aneurysms in persons with one first-degree relative with subarachnoid haemorrhage

Hopmans, Esther M.; Ruigrok, Ynte M.; Bor, Anne S.E.; Rinkel, Gabriel J.E.; Koffijberg, Hendrik (SAGE Publications Inc., 2016-12-01)

Introduction: Although persons with one first-degree relative with aneurysmal subarachnoid haemorrhage have an increased risk of aneurysm formation and aneurysmal subarachnoid haemorrhage, screening them for unruptured ...
Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization

Tortosa, Elena; Adolfs, Youri; Fukata, Masaki; Pasterkamp, R. Jeroen; Kapitein, Lukas C; Hoogenraad, Casper C. (Cell Press, 2017-05-17)

Microtubule-associated proteins (MAPs) are main candidates to stabilize neuronal microtubules, playing an important role in establishing axon-dendrite polarity. However, how MAPs are selectively targeted to specific neuronal ...

Now showing items 28881-28900 of 40729