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UMC Repository: Recent submissions

  • Neuroharmony: A new tool for harmonizing volumetric MRI data from unseen scanners 
    Garcia-Dias, Rafael; Scarpazza, Cristina; Baecker, Lea; Vieira, Sandra; Pinaya, Walter H L; Corvin, Aiden; Redolfi, Alberto; Nelson, Barnaby; Crespo-Facorro, Benedicto; McDonald, Colm; Tordesillas-Gutiérrez, Diana; Cannon, Dara; Mothersill, David; Hernaus, Dennis; Morris, Derek; Setien-Suero, Esther; Donohoe, Gary; Frisoni, Giovanni; Tronchin, Giulia; Sato, João; Marcelis, Machteld; Kempton, Matthew; van Haren, Neeltje E M; Gruber, Oliver; McGorry, Patrick; Amminger, Paul; McGuire, Philip; Gong, Qiyong; Kahn, René S; Ayesa-Arriola, Rosa; van Amelsvoort, Therese; Ortiz-García de la Foz, Victor; Calhoun, Vince; Cahn, Wiepke; Mechelli, Andrea (Academic Press Inc., 2020-10-15)
  • Cardiomyocyte Specific Deletion of ADAR1 Causes Severe Cardiac Dysfunction and Increased Lethality 
    El Azzouzi, Hamid; Vilaça, Andreia P; Feyen, Dries A M; Gommans, Willemijn M; de Weger, Roel A; Doevendans, Pieter A F; Sluijter, Joost P.G. (Frontiers Media S. A., 2020-03-18)
    Background: Adenosine deaminase acting on RNA 1 (ADAR1) is a double-stranded RNA-editing enzyme that is involved in several functions including the deamination of adenosine to inosine, RNA interference (RNAi) mechanisms ...
  • Development of an algorithm for automatic classification of right ventricle deformation patterns in arrhythmogenic right ventricular cardiomyopathy 
    Groen, Marijn H A; Bosman, Laurens P; Teske, Arco J; Mast, Thomas P; Taha, Karim; Van Slochteren, Frebus J; Cramer, Maarten J; Doevendans, Pieter A; van Es, René (Wiley-Blackwell, 2020-05)
    Background: Different disease stages of arrhythmogenic right ventricular cardiomyopathy (ARVC) can be identified by right ventricle (RV) longitudinal deformation (strain) patterns. This requires assessment of the onset of ...
  • The utility of the oxygen pulse recovery as a marker of the cardiac output response to exercise in patients with chronic heart failure 
    Spee, Ruud F; Niemeijer, Victor M; Thijssen, Carlijn G E; Hoogeveen, Adwin; Wijn, Pieter F F; Doevendans, Pieter A; Kemps, Hareld M C (Wiley-Blackwell, 2020-09)
    PURPOSE: The cardiac output (CO) response to exercise is a useful marker to grade the prognosis and severity of chronic heart failure (CHF). The recovery of the oxygen pulse (OP) is a non-invasive parameter, which is related ...
  • Automatic Triage of 12-Lead ECGs Using Deep Convolutional Neural Networks 
    van de Leur, Rutger R; Blom, Lennart J; Gavves, Efstratios; Hof, Irene E; van der Heijden, Jeroen F; Clappers, Nick C; Doevendans, Pieter A; Hassink, Rutger J; van Es, René (Wiley-Blackwell, 2020-05-18)
    BACKGROUND The correct interpretation of the ECG is pivotal for the accurate diagnosis of many cardiac abnormalities, and conventional computerized interpretation has not been able to reach physician-level accuracy in ...
  • Loss of miR-132/212 Has No Long-Term Beneficial Effect on Cardiac Function After Permanent Coronary Occlusion in Mice 
    Lei, Zhiyong; Fang, Juntao; Deddens, Janine C; Metz, Corina H G; van Eeuwijk, Esther C M; El Azzouzi, Hamid; Doevendans, Pieter A; Sluijter, Joost P G (Frontiers Research Foundation, 2020-06)
    Background: Myocardial infarction (MI) is caused by occlusion of the coronary artery and induces ischemia in the myocardium and eventually a massive loss in cardiomyocytes. Studies have shown many factors or treatments ...
  • gplas: a comprehensive tool for plasmid analysis using short-read graphs 
    Arredondo-Alonso, Sergio; Bootsma, Martin; Hein, Yaïr; Rogers, Malbert R.C.; Corander, Jukka; Willems, Rob J.L.; Schürch, Anita C. (Oxford University Press, 2020-06-15)
    Plasmids can horizontally transmit genetic traits, enabling rapid bacterial adaptation to new environments and hosts. Short-read whole-genome sequencing data are often applied to large-scale bacterial comparative genomics ...
  • Low IgA Associated With Oropharyngeal Microbiota Changes and Lung Disease in Primary Antibody Deficiency 
    Berbers, Roos Marijn; Mohamed Hoesein, Firdaus A.A.; Ellerbroek, Pauline M.; van Montfrans, Joris M.; Dalm, Virgil A.S.H.; van Hagen, P. Martin; Paganelli, Fernanda L.; Viveen, Marco C.; Rogers, Malbert R.C.; de Jong, Pim A.; Uh, Hae Won; Willems, Rob J.L.; Leavis, Helen L. (Frontiers Media S. A., 2020-06-19)
    Common Variable Immunodeficiency (CVID) and X-linked agammaglobulinemia (XLA) are primary antibody deficiencies characterized by hypogammaglobulinemia and recurrent infections, which can lead to structural airway disease ...
  • Predicting future suicidal behaviour in young adults, with different machine learning techniques: A population-based longitudinal study 
    van Mens, Kasper; de Schepper, C. W.M.; Wijnen, Ben; Koldijk, Saskia J.; Schnack, Hugo; de Looff, Peter; Lokkerbol, Joran; Wetherall, Karen; Cleare, Seonaid; C O'Connor, Rory; de Beurs, Derek (Elsevier, 2020-06-15)
    Background: The predictive accuracy of suicidal behaviour has not improved over the last decades. We aimed to explore the potential of machine learning to predict future suicidal behaviour using population-based longitudinal ...
  • The YOUth cohort study: MRI protocol and test-retest reliability in adults 
    Buimer, Elizabeth E.L.; Pas, Pascal; Brouwer, Rachel M.; Froeling, Martijn; Hoogduin, Hans; Leemans, Alexander; Luijten, Peter; van Nierop, Bastiaan J.; Raemaekers, Mathijs; Schnack, Hugo G.; Teeuw, Jalmar; Vink, Matthijs; Visser, Fredy; Hulshoff Pol, Hilleke E.; Mandl, René C.W. (Elsevier, 2020-10)
    The YOUth cohort study is a unique longitudinal study on brain development in the general population. As part of the YOUth study, 2000 children will be included at 8, 9 or 10 years of age and planned to return every three ...
  • Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries 
    Zheng, Ju Sheng; Sharp, Stephen J.; Imamura, Fumiaki; Chowdhury, Rajiv; Gundersen, Thomas E.; Steur, Marinka; Sluijs, Ivonne; Van Der Schouw, Yvonne T.; Agudo, Antonio; Aune, Dagfinn; Barricarte, Aurelio; Boeing, Heiner; Chirlaque, María Dolores; Dorronsoro, Miren; Freisling, Heinz; El-Fatouhi, Douae; Franks, Paul W.; Fagherazzi, Guy; Grioni, Sara; Gunter, Marc J.; Kyrø, Cecilie; Katzke, Verena; Kühn, Tilman; Khaw, Kay Tee; Laouali, Nasser; Masala, Giovanna; Nilsson, Peter M.; Overvad, Kim; Panico, Salvatore; Papier, Keren; Quirós, J. Ramón; Rolandsson, Olov; Redondo-Sánchez, Daniel; Ricceri, Fulvio; Schulze, Matthias B.; Spijkerman, Annemieke M.W.; Tjønneland, Anne; Tong, Tammy Y.N.; Tumino, Rosario; Weiderpass, Elisabete; Danesh, John; Butterworth, Adam S.; Riboli, Elio; Forouhi, Nita G.; Wareham, Nicholas J. (BMJ Publishing Group, 2020-07-08)
    OBJECTIVE: To investigate the association of plasma vitamin C and carotenoids, as indicators of fruit and vegetable intake, with the risk of type 2 diabetes. DESIGN: Prospective case-cohort study. SETTING: Populations from ...
  • Intimal and medial calcification in relation to cardiovascular risk factors 
    SMART Study Group (Public Library of Science, 2020-07-13)
    PURPOSE: To assess specific risk factors and biomarkers associated with intimal arterial calcification (IAC) and medial arterial calcification (MAC). METHODS: We conducted a cross-sectional study in patients with or at ...
  • Dexamethasone for the Prevention of a Pain Flare After Palliative Radiation Therapy for Painful Bone Metastases: The Multicenter Double-Blind Placebo-Controlled 3-Armed Randomized Dutch DEXA Study 
    van der Linden, Yvette M.; Westhoff, Paulien G.; Stellato, Rebecca K.; van Baardwijk, Angela; de Vries, Kim; Ong, Francisca; Wiggenraad, Ruud; Bakri, Bonnie; Wester, Gerda; de Pree, Ilse; van Veelen, Lieneke; Budiharto, Tom; Schippers, Maaike; Reyners, Anna K.L.; de Graeff, Alexander (Elsevier, 2020-11-01)
    PURPOSE: After radiation therapy for painful bone metastases, up to 44% of patients report a pain flare (PF). Our study compared 2 dose schedules of dexamethasone versus placebo to prevent PF. METHODS AND MATERIALS: This ...
  • GP trainees' perceptions on learning EBM using conversations in the workplace: a video-stimulated interview study 
    Welink, Lisanne S; de Groot, Esther; Pype, Peter; Van Roy, Kaatje; van den Wittenboer, Iris D; Bartelink, Marie-Louise E L; Damoiseaux, Roger A M J (BioMed Central, 2020-05-06)
    BACKGROUND: To be able to practice evidence-based medicine (EBM) when making decisions for individual patients, it is important to learn how to combine the best available evidence with the patient's preferences and the ...
  • Chances for learning intraprofessional collaboration between residents in hospitals 
    Looman, Natasja; Fluit, Cornelia; van Wijngaarden, Marielle; de Groot, Esther; Dielissen, Patrick; van Asselt, Dieneke; de Graaf, Jacqueline; Scherpbier-de Haan, Nynke (Wiley-Blackwell, 2020-12)
    Context: Intraprofessional collaboration (intraPC) between primary care (PC) doctors and medical specialists (MSs) is becoming increasingly important. Patient safety issues are often related to intraPC. In order to equip ...
  • Interactional implications of either/or-questions during telephone triage of callers with chest discomfort in out-of-hours primary care: A conversation analysis 
    Erkelens, Daphne C; van Charldorp, Tessa C; Vinck, Vera V; Wouters, Loes T; Damoiseaux, Roger A; Rutten, Frans H; Zwart, Dorien L; de Groot, Esther (Elsevier Ireland Ltd, 2021-02)
    OBJECTIVE: To explore the interactional implications of either/or-questions on the interaction between people who call out-of-hours services in primary care (OHS-PC) and triage nurses who use a decision support tool called ...
  • Interventional Ductoscopy as an Alternative for Major Duct Excision or Microdochectomy in Women Suffering Pathologic Nipple Discharge: A Single-center Experience 
    Filipe, Mando Dyko; Waaijer, Laurien; van der Pol, Carmen; van Diest, Paul Joannes; Witkamp, Arjen Joost (Elsevier, 2020-06)
    Introduction: Pathologic nipple discharge (PND) is, after palpable lumps and pain, the most common breast-related reason for referral to the breast surgeon and is associated with breast cancer. However, with negative ...
  • Organoids can be established reliably from cryopreserved biopsy catheter-derived endometrial tissue of infertile women 
    Bui, Bich Ngoc; Boretto, Matteo; Kobayashi, Hiroto; van Hoesel, Marliek; Steba, Gaby S.; van Hoogenhuijze, Nienke; Broekmans, Frank J.M.; Vankelecom, Hugo; Torrance, Helen L. (Elsevier, 2020-09)
    Research question: Can organoids be established from endometrial tissue of infertile women and does tissue cryopreservation allow for establishment of organoids comparable to organoids derived from freshly biopsied endometrial ...
  • Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes 
    Buikema, Jan W; Lee, Soah; Goodyer, William R; Maas, Renee G; Chirikian, Orlando; Li, Guang; Miao, Yi; Paige, Sharon L; Lee, Daniel; Wu, Haodi; Paik, David T; Rhee, Siyeon; Tian, Lei; Galdos, Francisco X; Puluca, Nazan; Beyersdorf, Benjamin; Hu, James; Beck, Aimee; Venkamatran, Sneha; Swami, Srilatha; Wijnker, Paul; Schuldt, Maike; Dorsch, Larissa M; van Mil, Alain; Red-Horse, Kristy; Wu, Joy Y; Geisen, Caroline; Hesse, Michael; Serpooshan, Vahid; Jovinge, Stefan; Fleischmann, Bernd K; Doevendans, Pieter A; van der Velden, Jolanda; Garcia, K Christopher; Wu, Joseph C; Sluijter, Joost P G; Wu, Sean M (Cell Press, 2020-07-02)
    Deriving a large number of hiPSC-cardiomyocytes would be beneficial for large-scale tissue engineering and drug screening applications. Buikema et al. show that GSK-3β inhibition combined with removal of cell-cell contact ...
  • In memory of Hein Wellens: unique scientist, teacher, doctor and friend 
    Gorgels, A P M; Doevendans, P A; Wilde, A A M (Bohn Stafleu van Loghum, 2020-07)