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UMC Repository: Recent submissions

  • Home Treatment Compared to Initial Hospitalization in Normotensive Patients with Acute Pulmonary Embolism in the Netherlands: A Cost Analysis 
    Hendriks, Stephan V; van den Hout, Wilbert B; van Bemmel, Thomas; Bistervels, Ingrid M; Eijsvogel, Michiel; Faber, Laura M; Hofstee, Herman M A; van der Hulle, Tom; Iglesias Del Sol, Antonio; Mairuhu, Albert T A; Middeldorp, Saskia; Nijkeuter, Mathilde; Huisman, Menno V; Klok, Frederikus A; YEARS Investigators (Schattauer GmbH, 2022-03-01)
    BACKGROUND: Venous thromboembolism constitutes substantial health care costs amounting to approximately 60 million euros per year in the Netherlands. Compared with initial hospitalization, home treatment of pulmonary ...
  • Effect of an interactive, educational app about venous thromboembolism and anticoagulation on patient satisfaction: A randomized controlled trial 
    de Winter, M A; Timmers, T; Hovens, M M C; Iglesias Del Sol, A; Mairuhu, A T A; Kaasjager, H A H; Nijkeuter, M (Elsevier Limited, 2022-01)
    BACKGROUND: Adequate patient education is essential for patients to engage in shared decision-making when deciding to stop or continue anticoagulation after 3 months for venous thromboembolism (VTE). Our objectives were ...
  • Post-thrombotic syndrome after upper extremity deep vein thrombosis: An international Delphi consensus study 
    de Kleijn, Robert J C M F; Schropp, Ludo; van Hattum, Eline S; Ünlu, Çagdas; Middeldorp, Saskia; Nijkeuter, Mathilde; Westerink, Jan; Petri, Bart-Jeroen; de Borst, Gert J (Wiley-Blackwell, 2022-08-20)
    OBJECTIVES: Primary deep vein thrombosis of the upper extremity (UEDVT) is a rare condition but up to 60% of patients may develop post-thrombotic syndrome in the upper extremity (UE-PTS) with significant morbidity and ...
  • Thoracic outlet syndrome (TROTS) registry: A study protocol for the primary upper extremity deep venous thrombosis section 
    TROTS registry collaborators (Public Library of Science, 2023-01-06)
    INTRODUCTION: There is a lack of comprehensive and uniform data on primary upper extremity deep venous thrombosis (pUEDVT). pUEDVT includes venous thoracic outlet syndrome related upper extremity deep venous thrombosis ...
  • Current treatment strategies for primary upper extremity deep venous thrombosis; a retrospective observational multicenter case series 
    de Kleijn, R J C M F; Schropp, L; Westerink, J; Nijkeuter, M; van Laanen, J; Teijink, J; Ünlu, C; Vos, A W F; van Hattum, E S; Petri, B J; de Borst, G J (Frontiers Media S. A., 2022-12-22)
    INTRODUCTION: Current treatment strategies for primary upper extremity deep venous thrombosis (pUEDVT) range from conservative treatment with anticoagulation therapy to invasive treatment with thoracic outlet decompression ...
  • Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score 
    De Winter, Maria A.; Büller, Harry R.; Carrier, Marc; Cohen, Alexander T.; Hansen, John Bjarne; Kaasjager, Karin A.H.; Kakkar, Ajay K.; Middeldorp, Saskia; Raskob, Gary E.; Sørensen, Henrik T.; Visseren, Frank L.J.; Wells, Philip S.; Dorresteijn, Jannick A.N.; Nijkeuter, Mathilde; Braekkan, Sigrid K.; Burggraaf, Louise; Cannegieter, Suzanne C.; Farjat, Alfredo; Pap, Akos Ferenc; Goldhaber, Samuel; Grosso, Michael; Horváth-Puhó, Erzsebet; Lensing, Anthonie W.A.; Pieper, Karen; Schulman, Sam; Shi, Minggao; Virdone, Saverio (Oxford University Press, 2023-04-07)
    Aims: Deciding to stop or continue anticoagulation for venous thromboembolism (VTE) after initial treatment is challenging, as individual risks of recurrence and bleeding are heterogeneous. The present study aimed to develop ...
  • Neural basis of positive and negative emotion regulation in remitted depression 
    van Kleef, Rozemarijn S; Marsman, Jan-Bernard C; van Valen, Evelien; Bockting, Claudi L H; Aleman, André; van Tol, Marie-José (Elsevier, 2022-01)
    The recurrent nature of Major Depressive Disorder (MDD) necessitates a better understanding of mechanisms facilitating relapse. MDD has often been associated with abnormal emotion regulation, underpinned by aberrant ...
  • CiliaCarta: An integrated and validated compendium of ciliary genes 
    van Dam, Teunis J P; Kennedy, Julie; van der Lee, Robin; de Vrieze, Erik; Wunderlich, Kirsten A; Rix, Suzanne; Dougherty, Gerard W; Lambacher, Nils J; Li, Chunmei; Jensen, Victor L; Leroux, Michel R; Hjeij, Rim; Horn, Nicola; Texier, Yves; Wissinger, Yasmin; van Reeuwijk, Jeroen; Wheway, Gabrielle; Knapp, Barbara; Scheel, Jan F; Franco, Brunella; Mans, Dorus A; van Wijk, Erwin; Képès, François; Slaats, Gisela G; Toedt, Grischa; Kremer, Hannie; Omran, Heymut; Szymanska, Katarzyna; Koutroumpas, Konstantinos; Ueffing, Marius; Nguyen, Thanh-Minh T; Letteboer, Stef J F; Oud, Machteld M; van Beersum, Sylvia E C; Schmidts, Miriam; Beales, Philip L; Lu, Qianhao; Giles, Rachel H; Szklarczyk, Radek; Russell, Robert B; Gibson, Toby J; Johnson, Colin A; Blacque, Oliver E; Wolfrum, Uwe; Boldt, Karsten; Roepman, Ronald; Hernandez-Hernandez, Victor; Huynen, Martijn A (Public Library of Science, 2019-05)
    The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wide range of genetic diseases collectively called ciliopathies. The current rate at which new ciliopathy genes are identified ...
  • Primary cilia suppress Ripk3-mediated necroptosis 
    Kieckhöfer, Emilia; Slaats, Gisela G; Ebert, Lena K; Albert, Marie-Christine; Dafinger, Claudia; Kashkar, Hamid; Benzing, Thomas; Schermer, Bernhard (Nature Publishing Group, 2022-12-02)
    Cilia are sensory organelles that project from the surface of almost all cells. Nephronophthisis (NPH) and NPH-related ciliopathies are degenerative genetic diseases caused by mutation of cilia-associated genes. These ...
  • Colonoscopy-Assisted Laparoscopic Wedge Resection for the Treatment of Suspected T1 Colon Cancer 
    Hanevelt, Julia; Moons, Leon M G; Hentzen, Judith E K R; Wemeijer, Tess M; Huisman, Jelle F; de Vos Tot Nederveen Cappel, Wouter H; van Westreenen, Henderik L (Springer New York, 2023-04)
    Background: Local en bloc resection of pT1 colon cancer has been gaining acceptance during the last few years. In the absence of histological risk factors, the risk of lymph-node metastases (LNM) is negligible and does not ...
  • Cerebral amyloid-β deposition in patients with heart disease or carotid occlusive disease: A systematic review and meta-analysis 
    Starmans, Naomi Louisa Paula; Leeuwis, Anna Elisabeth; Biessels, Geert Jan; Kappelle, Laurens Jaap; van der Flier, Wiesje Maria; Tolboom, Nelleke (Elsevier, 2023-02-15)
    BACKGROUND: Cardiovascular disease is an important contributor to cognitive impairment. This likely involves prototypical vascular disease mechanisms like ischemia, but cardiovascular disease might also impact the brain ...
  • Twenty-four hour blood pressure variability and the prevalence and the progression of cerebral white matter hyperintensities 
    Heart-Brain Connection Consortium (SAGE Publications Inc., 2023-05)
    Blood pressure variability (BPV) is related to cerebral white matter hyperintensities (WMH), but longitudinal studies assessing WMH progression are scarce. Patients with cardiovascular disease and control participants of ...
  • Adaptive radiotherapy for breast cancer 
    De-Colle, C; Kirby, A; Russell, N; Shaitelman, S F; Currey, A; Donovan, E; Hahn, E; Han, K; Anandadas, C N; Mahmood, F; Lorenzen, E L; van den Bongard, D; Groot Koerkamp, M L; Houweling, A C; Nachbar, M; Thorwarth, D; Zips, D (Elsevier Ireland Ltd, 2023-03)
    Research in the field of local and locoregional breast cancer radiotherapy aims to maintain excellent oncological outcomes while reducing treatment-related toxicity. Adaptive radiotherapy (ART) considers variations in ...
  • Biomarkers for Cyclin-Dependent Kinase 4/6 Inhibitors in the Treatment of Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Advanced/Metastatic Breast Cancer: Translation to Clinical Practice 
    Bui, Tam Binh V.; Burgering, Boudewijn M.T.; Goga, Andrei; Rugo, Hope S.; Van 'T Veer, Laura J. (Lippincott Williams & Wilkins, 2022-06-01)
    PURPOSECyclin-dependent kinase 4/6 (CDK4/6) inhibitors have emerged as effective treatments for patients with hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) advanced/metastatic ...
  • Identifying a core symptom set triggering radiological and endoscopic investigations for suspected recurrent esophago-gastric cancer: a modified Delphi consensus process 
    Chidambaram, Swathikan; Patel, Nikhil M.; Sounderajah, Viknesh; Alfieri, Rita; Bonavina, Luigi; Cheong, Edward; Cockbain, Andy; D'Journo, Xavier Benoit; Ferri, Lorenzo; Griffiths, Ewen A.; Grimminger, Peter; Gronnier, Caroline; Gutschow, Christian; Hedberg, Jakob; Kauppila, Joonas H.; Lagarde, Sjoerd; Low, Donald; Nafteux, Philippe; Nieuwenhuijzen, Grard; Nilsson, Magnus; Rosati, Riccardo; Schroeder, Wolfgang; Smithers, B. Mark; van Berge Henegouwen, Mark I.; van Hillegesberg, Richard; Watson, David I.; Vohra, Ravinder; Maynard, Nick; Markar, Sheraz R. (Wiley-Blackwell, 2022-12-31)
    BACKGROUND: There is currently a lack of evidence-based guidelines regarding surveillance for recurrence after esophageal and gastric (OG) cancer surgical resection, and which symptoms should prompt endoscopic or radiological ...
  • A path to translation: How 3D patient tumor avatars enable next generation precision oncology 
    Shree Bose (Cell Press, 2022-12-12)
    3D patient tumor avatars (3D-PTAs) hold promise for next-generation precision medicine. Here, we describe the benefits and challenges of 3D-PTA technologies and necessary future steps to realize their potential for clinical ...
  • Synovial-Based Tests Outperform Serum Markers to Rule Out Infection in Total Knee Arthroplasty and Total Hip Arthroplasty: A Systematic Review and Meta-Analysis 
    Goud, Annemarie; Nützinger, Don; van der Bij, Akke; Jenniskens, Kevin; Groenewold, Joel; de Gast, Arthur; Bekkers, Joris E.J. (Churchill Livingstone, 2022-04)
    Background: Total knee arthroplasty (TKA) provides successful results in most patients. Periprosthetic joint infection (PJI) accounts for up to 25% of failed TKAs needing revision. In clinical practice, consensus in ...
  • Added Diagnostic Value of Biomarkers in Patients with Suspected Sepsis: A Prospective Cohort Study in Out-Of-Hours Primary Care 
    Loots, Feike J.; Smits, Marleen; Jenniskens, Kevin; van Zanten, Arthur R.H.; Kusters, Ron; Verheij, Theo J.M.; Hopstaken, Rogier M. (Oxford University Press, 2022-09-01)
    BACKGROUND: Point-of-care testing (POCT) has shown promising results in the primary care setting to improve antibiotic therapy in respiratory tract infections and it might also aid general practitioners (GPs) to decide if ...
  • De Bevordering van Zelfregulatie Tijdens Afstandsonderwijs en Contactonderwijs: ervaringen tijdens de Covid-19 pandemie 
    Pennings, Helena J. M.; Manders, Floor (Vereniging voor Onderwijs Research (VOR), 2022)
    Zelfregulatie is essentieel voor leren, zeker tijdens afstandsonderwijs. Een onderwijsvorm waarmee leerlingen en leerkrachten te maken kregen tijdens de Covid-19 pandemie. Leerkrachten zijn belangrijke initiators voor de ...
  • Receiving Feedback Is Not Easy! Six Common Pitfalls 
    Tielemans, Claudia J M; Eijkelboom, Charlotte M C L; Lesterhuis, Marije; de Vreugd, Lars B; Pennings, Helena J M; de Kleijn, Renske A M (Wolters Kluwer, 2023-05-01)