A path to translation: How 3D patient tumor avatars enable next generation precision oncology

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A path to translation: How 3D patient tumor avatars enable next generation precision oncology
 
Shree Bose
(2022) Cancer Cell, volume 40, issue 12, pp. 1448 - 1453
(Comment)
Abstract
3D patient tumor avatars (3D-PTAs) hold promise for next-generation precision medicine. Here, we describe the benefits and challenges of 3D-PTA technologies and necessary future steps to realize their potential for clinical decision making. 3D-PTAs require standardization criteria and prospective trials to establish clinical benefits. Innovative trial designs that combine omics ... read more
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Keywords: Oncology, Cancer Research
DOI: https://doi.org/10.1016/j.ccell.2022.09.017
ISSN: 1535-6108
Publisher: Cell Press
Note: Funding Information: We thank the NCI 3D Workshop, Patient-Derived Model of Cancer (PDMC) Program, and PDXNet for constructive discussions, recommendations, and purposeful efforts to advance the practice of precision oncology. This work was supported by National Cancer Institute grants NIH-U01CA217514 and U01CA214300 as well as National Institutes of Health F30 fellowship 1F30CA257365-01 . Publisher Copyright: © 2022 Elsevier Inc.
(Peer reviewed)