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UMC Repository: Recent submissions

  • Emotional face recognition in male adolescents with autism spectrum disorder or disruptive behavior disorder: an eye-tracking study 
    Bours, C. C.A.H.; Bakker-Huvenaars, M. J.; Tramper, J.; Bielczyk, N.; Scheepers, F.; Nijhof, K. S.; Baanders, A. N.; Lambregts-Rommelse, N. N.J.; Medendorp, P.; Glennon, J. C.; Buitelaar, J. K. (Springer Science and Business Media Deutschland GmbH, 2018-09)
    Autism Spectrum Disorder (ASD), Oppositional Defiant Disorder (ODD), and Conduct Disorder (CD) are often associated with emotion recognition difficulties. This is the first eye-tracking study to examine emotional face ...
  • Childhood abuse and white matter integrity in bipolar disorder patients and healthy controls 
    Stevelink, Remi; Abramovic, Lucija; Verkooijen, Sanne; Begemann, Marieke J.H.; Sommer, Iris E.C.; Boks, Marco P.; Mandl, Rene C.W.; van Haren, Neeltje E.M.; Vinkers, Christiaan H. (Elsevier, 2018-07)
    Childhood trauma has a negative impact on the developing brain and increases the risk for almost all psychiatric disorders including bipolar disorder. White matter abnormalities may play a role in the persistently increased ...
  • Endothelial loss of Fzd5 stimulates PKC/Ets1-mediated transcription of Angpt2 and Flt1 
    Brandt, Maarten M; van Dijk, Christian G M; Chrifi, Ihsan; Kool, Heleen M; Bürgisser, Petra E; Louzao-Martinez, Laura; Pei, Jiayi; Rottier, Robbert J; Verhaar, Marianne C; Duncker, Dirk J; Cheng, Caroline (Springer Netherlands, 2018-11)
    AIMS: Formation of a functional vascular system is essential and its formation is a highly regulated process initiated during embryogenesis, which continues to play important roles throughout life in both health and disease. ...
  • Exploratory study of the course of posttraumatic stress disorder after aneurysmal subarachnoid hemorrhage 
    Huenges Wajer, Irene M.C.; Smits, Anouk R.; Rinkel, Gabriel J.E.; van Zandvoort, Martine J.E.; Wijngaards-de Meij, Leoniek; Visser-Meily, Johanna M.A. (Elsevier, 2018-07-01)
    Objective: Posttraumatic stress disorder (PTSD) occurs often in aneurysmal subarachnoid hemorrhage (aSAH) survivors, but how PTSD develops over time post-aSAH is still unclear. We examined the course of PTSD symptoms during ...
  • Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton–Valentine leukocidin 
    Tromp, Angelino T.; van Gent, Michiel; Abrial, Pauline; Martin, Amandine; Jansen, Joris P.; de Haas, Carla J.C.; van Kessel, Kok P.M.; Bardoel, Bart W.; Kruse, Elisabeth; Bourdonnay, Emilie; Boettcher, Michael; McManus, Michael T.; Day, Christopher J.; Jennings, Michael P.; Lina, Gérard; Vandenesch, François; van Strijp, Jos A.G.; Jan Lebbink, Robert; Haas, Pieter Jan A.; Henry, Thomas; Spaan, András N. (Nature Research, 2018-06)
    The staphylococcal bi-component leukocidins Panton–Valentine leukocidin (PVL) and γ-haemolysin CB (HlgCB) target human phagocytes. Binding of the toxins’ S-components to human complement C5a receptor 1 (C5aR1) contributes ...
  • De novo mutations in MED13, a component of the Mediator complex, are associated with a novel neurodevelopmental disorder 
    Snijders Blok, Lot; Hiatt, Susan M; Bowling, Kevin M; Prokop, Jeremy W; Engel, Krysta L; Cochran, J Nicholas; Bebin, E Martina; Bijlsma, Emilia K; Ruivenkamp, Claudia A L; Terhal, Paulien; Simon, Marleen E H; Smith, Rosemarie; Hurst, Jane A; McLaughlin, Heather; Person, Richard; Crunk, Amy; Wangler, Michael F; Streff, Haley; Symonds, Joseph D; Zuberi, Sameer M; Elliott, Katherine S; Sanders, Victoria R; Masunga, Abigail; Hopkin, Robert J; Dubbs, Holly A; Ortiz-Gonzalez, Xilma R; Pfundt, Rolph; Brunner, Han G; Fisher, Simon E; Kleefstra, Tjitske; Cooper, Gregory M; DDD Study (Springer-Verlag, 2018-05-01)
    Many genetic causes of developmental delay and/or intellectual disability (DD/ID) are extremely rare, and robust discovery of these requires both large-scale DNA sequencing and data sharing. Here we describe a GeneMatcher ...
  • Dutch guideline for clinical foetal-neonatal and paediatric post-mortem radiology, including a review of literature 
    Sonnemans, L. J.P.; Vester, M. E.M.; Kolsteren, E. E.M.; Erwich, J. J.H.M.; Nikkels, P. G.J.; Kint, P. A.M.; van Rijn, R. R.; Klein, W. M.; Duijst, W. L.J.M.; Hofman, P. A.M.; Kroll, J. J.F.; Renken, N. S.; Rosier, Y. O.; Scheeren, C. I.E.; Stomp, S. J.; van der Valk, P.; On Behalf Of The Dutch Post-Mortem Imaging Guideline Group (Springer-Verlag, 2018-06)
    Clinical post-mortem radiology is a relatively new field of expertise and not common practice in most hospitals yet. With the declining numbers of autopsies and increasing demand for quality control of clinical care, ...
  • A clinicopathological study and prognostic factor analysis of 177 salivary duct carcinoma patients from The Netherlands 
    Boon, Eline; Bel, Miranda; van Boxtel, Wim; van der Graaf, Winette T.A.; van Es, Robert J.J.; Eerenstein, Simone E.J.; Baatenburg de Jong, Robert J.; van den Brekel, Michiel W.M.; van der Velden, Lilly Ann; Witjes, Max J.H.; Hoeben, Ann; Willems, Stefan M.; Bloemena, Elisabeth; Smit, Laura A.; Oosting, Sjoukje F.; Jonker, Marianne A.; Flucke, Uta E.; van Herpen, Carla M.L. (John Wiley & Sons Inc., 2018-08-15)
    Salivary duct carcinoma (SDC) is a subtype of salivary gland cancer with a dismal prognosis and a need for better prognostication and novel treatments. The aim of this national cohort study was to investigate clinical ...
  • Automated video-based detection of nocturnal convulsive seizures in a residential care setting 
    Geertsema, Evelien E.; Thijs, Roland D.; Gutter, Therese; Vledder, Ben; Arends, Johan B.; Leijten, Frans S.; Visser, Gerhard H.; Kalitzin, Stiliyan N. (Wiley-Blackwell, 2018-06)
    People with epilepsy need assistance and are at risk of sudden death when having convulsive seizures (CS). Automated real-time seizure detection systems can help alert caregivers, but wearable sensors are not always ...
  • A mutation update on the LDS-associated genes TGFB2/3 and SMAD2/3 
    Schepers, Dorien; Tortora, Giada; Morisaki, Hiroko; Maccarrick, Gretchen; Lindsay, Mark; Liang, David; Mehta, Sarju G.; Hague, Jennifer; Verhagen, Judith; van de Laar, Ingrid; Wessels, Marja; Detisch, Yvonne; van Haelst, Mieke; Baas, Annette; Lichtenbelt, Klaske; Braun, Kees; van der Linde, Denise; Roos-Hesselink, Jolien; Mcgillivray, George; Meester, Josephina; Maystadt, Isabelle; Coucke, Paul; El-Khoury, Elie; Parkash, Sandhya; Diness, Birgitte; Risom, Lotte; Scurr, Ingrid; Hilhorst-Hofstee, Yvonne; Morisaki, Takayuki; Richer, Julie; Désir, Julie; Kempers, Marlies; Rideout, Andrea L.; Horne, Gabrielle; Bennett, Chris; Rahikkala, Elisa; Vandeweyer, Geert; Alaerts, Maaike; Verstraeten, Aline; Dietz, Hal; Van Laer, Lut; Loeys, Bart (John Wiley & Sons Inc., 2018-05)
    The Loeys-Dietz syndrome (LDS) is a connective tissue disorder affecting the cardiovascular, skeletal, and ocular system. Most typically, LDS patients present with aortic aneurysms and arterial tortuosity, hypertelorism, ...
  • Autosomal recessive Noonan syndrome associated with biallelic LZTR1 variants 
    Members of the Undiagnosed Diseases Network (Lippincott Williams & Wilkins, 2018-10-01)
    Purpose: To characterize the molecular genetics of autosomal recessive Noonan syndrome. Methods: Families underwent phenotyping for features of Noonan syndrome in children and their parents. Two multiplex families underwent ...
  • Effect of immediate and prolonged GLP-1 receptor agonist administration on uric acid and kidney clearance: post-hoc analyses of four clinical trials 
    Tonneijck, Lennart; Muskiet, Marcel H A; Smits, Mark M; Bjornstad, Petter; Kramer, Mark H H; Diamant, Michaela; Hoorn, Ewout J.; Joles, Jaap A; van Raalte, Daniël H (Wiley-Blackwell, 2018-05)
    Aims: To determine the effects of glucagon-like peptide (GLP)-1 receptor agonists (RA) on uric acid (UA) levels and kidney UA clearance. Material and methods: This study involved post-hoc analyses of 4 controlled clinical ...
  • Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models 
    Linnekamp, Janneke F.; Hooff, Sander R.Van; Prasetyanti, Pramudita R.; Kandimalla, Raju; Buikhuisen, Joyce Y.; Fessler, Evelyn; Ramesh, Prashanthi; Lee, Kelly A.S.T.; Bochove, Grehor G.W.; de Jong, Johan H.; Cameron, Kate; Leersum, Ronald Van; Rodermond, Hans M.; Franitza, Marek; Nürnberg, Peter; Mangiapane, Laura R.; Wang, Xin; Clevers, Hans; Vermeulen, Louis; Stassi, Giorgio; Medema, Jan Paul (Springer Nature, 2018-03)
    Colorectal cancer (CRC) is a highly heterogeneous disease both from a molecular and clinical perspective. Several distinct molecular entities, such as microsatellite instability (MSI), have been defined that make up ...
  • Blocking of opioid receptors in experimental formaline-inactivated respiratory syncytial virus (FI-RSV) immunopathogenesis: from beneficial to harmful impacts 
    Salimi, Vahid; Mirzaei, Habib; Ramezani, Ali; Tahamtan, Alireza; Jamali, Abbas; Shahabi, Shahram; Golaram, Maryam; Minaei, Bagher; Gharagozlou, Mohammad Javad; Mahmoodi, Mahmood; Bont, Louis; Shokri, Fazel; Mokhtari-Azad, Talat (Springer-Verlag, 2018-04-01)
    Opioid system plays a significant role in pathophysiological processes, such as immune response and impacts on disease severity. Here, we investigated the effect of opioid system on the immunopathogenesis of respiratory ...
  • Age of platelet concentrates and time to the next transfusion 
    Caram-Deelder, Camila; van der Bom, Johanna G; Putter, Hein; Leyte, Anja; van de Kerkhof, Daan; Evers, Dorothea; Beckers, Erik A M; Weerkamp, Floor; Hudig, Francisca; Zwaginga, Jaap Jan; Rondeel, Jan M.M.; de Vooght, Karen M.K.; Pe´que´riaux, Nathalie C.V.; Visser, Otto J; Wallis, Jonathan P.; Middelburg, Rutger A. (Wiley-Blackwell, 2018-01-01)
    BACKGROUND: Storage time of platelet (PLT) concentrates has been negatively associated with clinical efficacy outcomes. The aim of this study was to quantify the association between storage time of PLT concentrates and ...
  • Triblock copolymers based on ε-caprolactone and trimethylene carbonate for the 3D printing of tissue engineering scaffolds 
    Güney, Aysun; Malda, Jos; Dhert, Wouter J A; Grijpma, Dirk W. (Wichtig Publishing, 2017)
    Background: Biodegradable PCL-b-PTMC-b-PCL triblock copolymers based on trimethylene carbonate (TMC) and ε-caprolactone (CL) were prepared and used in the 3D printing of tissue engineering scaffolds. Triblock copolymers ...
  • Late recurrence of unilateral graves orbitopathy on the contralateral side 
    Kalmann, Rachel; Mourits, Maarten P. (Elsevier, 2002)
    PURPOSE: To report a case of late recurrence of unilateral Graves orbitopathy on the contralateral side after 7 years. DESIGN: Interventional case report. METHODS: A 44-year-old woman with left unilateral Graves orbitopathy ...
  • Coronal or swinging eyelid decompression for patients with disfiguring proptosis in Graves' orbitopathy?: Comparison of results in one center 
    Sasim, Inna V.; De Graaf, Mieke E.L.; Berendschot, Tos T.J.M.; Kalmann, Rachel; Van Isterdael, Chantal; Mourits, Maarten P. (Elsevier, 2005-07)
    Purpose: To compare 2 different approaches for 3-wall orbital decompression in patients with disfiguring proptosis due to Graves' orbitopathy, and to determine which technique is preferable. Design: Retrospective nonrandomized ...
  • Dexamethasone Downregulates Cryptococcus neoformans–Induced Vascular Endothelial Growth Factor Production: A Role for Corticosteroids in Cryptococcal Meningitis? 
    Hoepelman, Andy I.M.; Van Der Flier, Michiel; Coenjaerts, Frank E.J. (Lippincott Williams & Wilkins, 2004-11-01)
  • Double blind randomized placebo-controlled trial on the effects of testosterone supplementation in elderly men with moderate to low testosterone levels: Design and baseline characteristics [ISRCTN23688581] 
    Nakhai Pour, Hamid Reza; Emmelot-Vonk, Marielle H.; Sukel-Helleman, Marja; Verhaar, Harald J.J.; Grobbee, Diederick E.; van der Schouw, Yvonne T. (BioMed Central, 2006-08-03)
    In ageing men testosterone levels decline, while cognitive function, muscle and bone mass, sexual hair growth, libido and sexual activity decline and the risk of cardiovascular diseases increase. We set up a double-blind, ...