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Now showing items 7241-7260 of 40729

The association of premorbid conditions with 6-month mortality in acutely admitted ICU patients over 80 years

VIP2 study group (Springer-Verlag GmbH and Co. KG, 2024-03-30)

Background: Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on ...
Head-to-toe bedside ultrasound for adult patients on extracorporeal membrane oxygenation

Douflé, Ghislaine; Dragoi, Laura; Morales Castro, Diana; Sato, Kei; Donker, Dirk W.; Aissaoui, Nadia; Fan, Eddy; Schaubroeck, Hannah; Price, Susanna; Fraser, John F.; Combes, Alain (Springer-Verlag, 2024-05)

Bedside ultrasound represents a well-suited diagnostic and monitoring tool for patients on extracorporeal membrane oxygenation (ECMO) who may be too unstable for transport to other hospital areas for diagnostic tests. The ...
Left ventricular unloading in patients supported with veno-arterial extra corporeal membrane oxygenation; an international EuroELSO survey

Ezad, Saad M.; Ryan, Matthew; Barrett, Nicholas; Camporota, Luigi; Swol, Justyna; Antonini, Marta V.; Donker, Dirk W.; Pappalardo, Federico; Kapur, Navin K.; Rose, Louise; Perera, Divaka (SAGE Publications Ltd, 2024-04)

Introduction: Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) improves end-organ perfusion in cardiogenic shock but may increase afterload, which can limit cardiac recovery. Left ventricular (LV) unloading ...
The physiology of venoarterial extracorporeal membrane oxygenation -: A comprehensive clinical perspective

Fresiello, Libera; Hermens, Jeannine A.J.; Pladet, Lara; Meuwese, Christiaan L.; Donker, Dirk W. (SAGE Publications Ltd, 2024-04)

Venoarterial extracorporeal membrane oxygenation (VA ECMO) has become a standard of care for severe cardiogenic shock, refractory cardiac arrest and related impending multiorgan failure. The widespread clinical use of this ...
Heparin Dose Intensity and Organ Support-Free Days in Patients Hospitalized for COVID-19

Godoy, Lucas C.; Neal, Matthew D.; Goligher, Ewan C.; Cushman, Mary; Houston, Brett L.; Bradbury, Charlotte A.; McQuilten, Zoe K.; Tritschler, Tobias; Kahn, Susan R.; Berry, Lindsay R.; Lorenzi, Elizabeth; Jensen, Tom; Higgins, Alisa M.; Kornblith, Lucy Z.; Berger, Jeffrey S.; Gong, Michelle N.; Paul, Jonathan D.; Castellucci, Lana A.; Le Gal, Grégoire; Lother, Sylvain A.; Rosenson, Robert S.; Derde, Lennie P.G.; Kumar, Anand; McVerry, Bryan J.; Nicolau, Jose C.; Leifer, Eric; Escobedo, Jorge; Huang, David T.; Reynolds, Harmony R.; Carrier, Marc; Kim, Keri S.; Hunt, Beverley J.; Slutsky, Arthur S.; Turgeon, Alexis F.; Webb, Steven A.; McArthur, Colin J.; Farkouh, Michael E.; Hochman, Judith S.; Zarychanski, Ryan; Lawler, Patrick R. (Elsevier, 2024-03)

Background: Clinical trials suggest that therapeutic-dose heparin may prevent critical illness and vascular complications due to COVID-19, but knowledge gaps exist regarding the efficacy of therapeutic heparin including ...
Cardiotoxicity After Synthetic Cathinone Use: Two Cases, A Case Series and Scoping Review

Groenewegen, K L; Gresnigt, F M J; Lonkhuyzen, J J Nugteren-van; den Haan, C; Franssen, E J F; Riezebos, R K; Ohana, D; de Lange, D W (Humana Press, 2024-03)

The cardiotoxic effects of synthetic cathinones remain largely unknown. In this study, we present two cases, a case series and a scoping review, to explore synthetic cathinone associated cardiotoxicity. Case 1 involved a ...
Clinical decision making for VA ECMO weaning in patients with cardiogenic shock A formative qualitative study

Hermens, J. A.J.; van Til, J. A.; Meuwese, C. L.; van Dijk, D.; Donker, D. W. (SAGE Publications Ltd, 2024-04)

Weaning and liberation from VA ECMO in cardiogenic shock patients comprises a complex process requiring a continuous trade off between multiple clinical parameters. In the absence of dedicated international guidelines, we ...
The effect of proactive versus reactive treatment of hypotension on postoperative disability and outcome in surgical patients under anaesthesia (PRETREAT): clinical trial protocol and considerations

The PRETREAT study group (Elsevier, 2024-03)

Background: Intraoperative hypotension has been extensively studied for its association with adverse outcomes. However, small sample sizes and methodological issues limit the causal inference that can be drawn. Methods: ...
Delayed cardiac arrest after hydrofluoric acid ingestion

Kroes, J A; de Haan, J M H; de Haan-Lauteslager, M I; van Roon, E N; Derksen, S J; Manusama, E R; Zijlstra, G J; Gisbertz, S S; Vrijsen, B E L; Bethlehem, C (Informa Healthcare, 2024-03)
Two-step interpretable modeling of ICU-AIs

Lancia, G; Varkila, M R J; Cremer, O L; Spitoni, C (Elsevier, 2024-05)

We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining the ...
Monocyte state 1 (MS1) cells in critically ill patients with sepsis or non-infectious conditions: association with disease course and host response

Leite, Giuseppe G F; de Brabander, Justin; Michels, Erik H A; Butler, Joe M; Cremer, Olaf L; Scicluna, Brendon P; Sweeney, Timothy E; Reyes, Miguel; Salomao, Reinaldo; Peters-Sengers, Hessel; van der Poll, Tom (Springer Science + Business Media, 2024-12)

Background: Sepsis is a life-threatening condition arising from an aberrant host response to infection. Recent single-cell RNA sequencing investigations identified an immature bone-marrow-derived CD14+ monocyte phenotype ...
Single-channel qEEG characteristics distinguish delirium from no delirium, but not postoperative from non-postoperative delirium

Lodema, D Y; Ditzel, F L; Hut, S C A; van Dellen, E; Otte, W M; Slooter, A J C (Elsevier Ireland Ltd, 2024-05)

OBJECTIVE: This exploratory study examined quantitative electroencephalography (qEEG) changes in delirium and the use of qEEG features to distinguish postoperative from non-postoperative delirium. METHODS: This project was ...
Postoperative troponin surveillance to detect myocardial infarction: an observational cohort modelling study

Martinez-Perez, Selene; van Waes, Judith A.R.; Vernooij, Lisette M.; Cuthbertson, Brian H.; Beattie, W. Scott; Wijeysundera, Duminda N.; van Klei, Wilton A. (Oxford University Press, 2024-04)

Background: Clinical presentation of postoperative myocardial infarction (POMI) is often silent. Several international guidelines recommend routine troponin surveillance in patients at risk. We compared how these different ...
Biomarker patterns in patients with cardiogenic shock versus septic shock

Peters, Elma J.; Frydland, Martin S.; Hassager, Christian; Bos, Lieuwe D.J.; van Vught, Lonneke A.; Cremer, Olaf L.; Møller, Jacob E.; van den Born, Bert Jan H.; Vlaar, Alexander P.J.; Henriques, Jose P.S. (Elsevier, 2024-06)

Background: In cardiogenic shock (CS), contractile failure is often accompanied by a systemic inflammatory response syndrome. In contrast, many patients with septic shock (SS) develop cardiac dysfunction. A similar hemodynamic ...
Multidisciplinary strategies to treat painful mononeuropathies in the upper extremity: from lab to bedside

Rijsdijk, M.; Tuffaha, S.; Coert, J. H. (SAGE Publications Ltd, 2024-05-15)

Neuropathic pain in the upper extremity is a serious problem, commonly involving relatively young patients. The pain causes loss of function and productivity, changes a patient’s lifestyle and can progress into a chronic ...
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing

Rocchi, Maria; Papangelopoulou, Konstantina; Ingram, Marcus; Bekhuis, Youri; Claessen, Guido; Claus, Piet; D'hooge, Jan; Donker, Dirk W; Meyns, Bart; Fresiello, Libera (American Institute of Physics, 2024-05)

Cardiovascular medical devices undergo a large number of pre- and post-market tests before their approval for clinical practice use. Sophisticated cardiovascular simulators can significantly expedite the evaluation process ...
Reframing sepsis immunobiology for translation: towards informative subtyping and targeted immunomodulatory therapies

Shankar-Hari, Manu; Calandra, Thierry; Soares, Miguel P; Bauer, Michael; Wiersinga, W Joost; Prescott, Hallie C; Knight, Julian C; Baillie, Kenneth J; Bos, Lieuwe D J; Derde, Lennie P G; Finfer, Simon; Hotchkiss, Richard S; Marshall, John; Openshaw, Peter J M; Seymour, Christopher W; Venet, Fabienne; Vincent, Jean-Louis; Le Tourneau, Christophe; Maitland-van der Zee, Anke H; McInnes, Iain B; van der Poll, Tom (Elsevier Limited, 2024-04)

Sepsis is a common and deadly condition. Within the current model of sepsis immunobiology, the framing of dysregulated host immune responses into proinflammatory and immunosuppressive responses for the testing of novel ...
Inflammatory subphenotypes previously identified in ARDS are associated with mortality at intensive care unit discharge: a secondary analysis of a prospective observational study

Slim, Marleen A.; van Amstel, Rombout B.E.; Bos, Lieuwe D.J.; Cremer, Olaf L.; Wiersinga, W. Joost; van der Poll, Tom; van Vught, Lonneke A. (Springer Science + Business Media, 2024-05)

Background: Intensive care unit (ICU)-survivors have an increased risk of mortality after discharge compared to the general population. On ICU admission subphenotypes based on the plasma biomarker levels of interleukin-8, ...
The effect of immunosuppressive therapies on the endothelial host response in critically ill COVID-19 patients

Amsterdam UMC COVID-19 Biobank Study Group (Nature Publishing Group, 2024-04-20)

While several effective therapies for critically ill patients with COVID-19 have been identified in large, well-conducted trials, the mechanisms underlying these therapies have not been investigated in depth. Our aim is ...
Risk factors for deliberate self-poisoning among children and adolescents in The Netherlands

Thoonen, Ilze M J; Rietjens, Saskia J; van Velzen, Agnes G; de Lange, Dylan W; Koppen, Arjen (Informa Healthcare, 2024-01)

INTRODUCTION: In the past decade, the number of deliberate self-poisonings involving young people has increased strongly worldwide. This study aimed to gain insight into risk factors associated with deliberate self-poisonings ...

Now showing items 7241-7260 of 40729