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UMC Repository: Recent submissions

  • Cardiac magnetic resonance in advanced heart failure 
    Coraducci, Francesca; De Zan, Giulia; Fedele, Damiano; Costantini, Pietro; Guaricci, Andrea Igoren; Pavon, Anna Giulia; Teske, Arco; Cramer, Maarten Jan; Broekhuizen, Lysette; Van Osch, Dirk; Danad, Ibrahim; Velthuis, Birgitta; Suchá, Dominika; van der Bilt, Ivo; Pizzi, Carmine; Russo, Antonio Dello; Oerlemans, Marish; van Laake, Linda W; van der Harst, Pim; Guglielmo, Marco (Wiley-Blackwell, 2024-06)
    Heart failure (HF) is a chronic and progressive disease that often progresses to an advanced stage where conventional therapy is insufficient to relieve patients' symptoms. Despite the availability of advanced therapies ...
  • Mitral annular disjunction in idiopathic ventricular fibrillation patients: Just a bystander or a potential cause? 
    Verheul, L. M.; Guglielmo, M.; Groeneveld, S. A.; Kirkels, F. P.; Scrocco, C.; Cramer, M. J.; Bootsma, M.; Kapel, G. F.L.; Alings, M.; Evertz, R.; Mulder, B. A.; Prakken, N. H.J.; Balt, J. C.; Volders, P. G.A.; Hirsch, A.; Yap, S. C.; Postema, P. G.; Nijveldt, R.; Velthuis, B. K.; Behr, E. R.; Wilde, A. A.M.; Hassink, R. J. (Oxford University Press, 2024-06-01)
    Aims: Previously, we demonstrated that inferolateral mitral annular disjunction (MAD) is more prevalent in patients with idiopathic ventricular fibrillation (IVF) than in healthy controls. In the present study, we advanced ...
  • Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study 
    ORFAN Consortium (Elsevier, 2024-06-15)
    Background: Coronary computed tomography angiography (CCTA) is the first line investigation for chest pain, and it is used to guide revascularisation. However, the widespread adoption of CCTA has revealed a large group of ...
  • NOGGIN INHIBITS TGF-β1 OR TGF-β3 INDUCED CHONDROGENESIS OF MESENCHYMAL STROMAL CELLS 
    Wen, L.; Armiento, A. R.; Guex, A. G.; Grad, S.; Creemers, L.; Stoddart, M. J. (Forum Multimedia Publishing LLC, 2024-01-01)
    Noggin (NOG) is an antagonist of bone morphogenetic proteins (BMPs), which regulates development and homeostasis of bone and cartilage. NOG has also been discovered to be an antagonist of transforming growth factor-β1 ...
  • Lifelong LUTS: Understanding the bladder's role and implications across transition phases, a comprehensive review 
    Kheir, George Bou; Verbakel, Irina; Wyndaele, Michel; Monaghan, Thomas F; Sinha, Sanjay; Larsen, Tove Holm; Van Laecke, Erik; Birder, Lori; Hervé, François; Everaert, Karel (John Wiley & Sons Inc., 2024-06)
    INTRODUCTION: Lower urinary tract symptoms (LUTSs) are a diverse array of urinary and pelvic dysfunctions that can emerge from childhood, extend through adulthood, and persist into older age. This narrative review aims to ...
  • Intermittent catheterisation: individuals’ rights, accessibility, and environmental concerns 
    Krassioukov, Andrei; Wyndaele, Michel; Walter, Matthias; Keppenne, Veronique; Welk, Blayne; Vrijens, Desiree; Theron, Francois (Nature Publishing Group, 2024-05-31)
  • Pathophysiology of urinary incontinence 
    Coblyn, Jonathan; Wyndaele, Michel; Hashim, Hashim (Elsevier, 2023-05)
    Urinary incontinence, or the complaint of involuntary loss of urine, is a debilitating condition of the lower urinary tract with a potentially significant impact on a patient's physical and mental wellbeing and on their ...
  • Iliac Branch Devices and Long-Term Technical Success: A Synergetic Relationship 
    Teraa, Martin; Bashir, Mohamad (W.B. Saunders Ltd, 2024-06)
  • Exploring lifelong overactive bladder: Transitions, evidence, and clinical implications; A modified Delphi process 
    Bou Kheir, George; Verbakel, Irina; Vande Walle, Johan; Wyndaele, Michel; Sinha, Sanjay; Arlandis, Salvador; Raes, Ann; Abrams, Paul; Wein, Alan; Hervé, François; Everaert, Karel (John Wiley & Sons Inc., 2024-06)
    INTRODUCTION: Overactive bladder (OAB) is a prevalent urological condition characterized by urinary urgency, with or without urgency urinary incontinence, accompanied by increased daytime frequency and nocturia. However, ...
  • A Modular Albumin-Oligonucleotide Biomolecular Assembly for Delivery of Antisense Therapeutics 
    Elkhashab, Marwa; Dilek, Yeter; Foss, Morten; Creemers, Laura B.; Howard, Kenneth A. (American Chemical Society, 2024-02-05)
    Antisense nucleic acid drugs are susceptible to nuclease degradation, rapid renal clearance, and short circulatory half-life. In this work, we introduce a modular-based recombinant human albumin-oligonucleotide (rHA-cODN) ...
  • Towards Equal Access to Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy and Survival in Patients with Isolated Colorectal Peritoneal Metastases: A Nationwide Population-Based Study 
    van der Ven, Roos G.F.M.; van den Heuvel, Teun B.M.; Rovers, Koen P.B.; Nienhuijs, Simon W.; Boerma, Djamila; van Grevenstein, Wilhelmina M.U.; Hemmer, Patrick H.J.; Kok, Niels F.M.; Madsen, Eva V.E.; de Reuver, Philip; Tuynman, Jurriaan B.; van Erning, Felice N.; de Hingh, Ignace H.J.T. (Springer New York, 2024-06)
    Background: Before 2016, patients with isolated synchronous colorectal peritoneal metastases (PMCRC) diagnosed in expert centers had a higher odds of undergoing cytoreductive surgery with hyperthermic intraperitoneal ...
  • The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia 
    Chouchane, Osoul; Schuurman, Alex R; Reijnders, Tom D Y; Peters-Sengers, Hessel; Butler, Joe M; Uhel, Fabrice; Schultz, Marcus J; Bonten, Marc J; Cremer, Olaf L; Calfee, Carolyn S; Matthay, Michael A; Langley, Raymond J; Alipanah-Lechner, Narges; Kingsmore, Stephen F; Rogers, Angela; Weeghel, Michel van; Vaz, Frédéric M; van der Poll, Tom (American Thoracic Society, 2024-04-15)
    Rationale: The plasma lipidome has the potential to reflect many facets of the host status during severe infection. Previous work is limited to specific lipid groups or was focused on lipids as prognosticators. Objectives: ...
  • Lipids in immunometabolism: From lipid handling to lipid antigen presentation and back 
    Morris, Imogen (Utrecht University, 2024-07-11)
    Within this thesis we utilized and developed several model systems allowing us to strategically address the different levels of complex interactions and mechanisms. In chapter 2 we use a mixture of FFA’s mimicking the ...
  • Multifocal motor neuropathy: Clinical, genetic, and immunological studies 
    Bos, Jeroen (Utrecht University, 2024-07-11)
    Multifocal motor neuropathy (MMN) is a very rare inflammatory neuropathy that leads to muscle weakness in mainly the hands and feet. IgM antibodies directed against the ganglioside GM1 can be found in at least 50% of ...
  • Periprosthetic joint infections: Development of new therapies 
    van Dijk, Bruce (Utrecht University, 2024-06-26)
    Summary Implants such as hip and knee prostheses have revolutionized healthcare by significantly improving quality of life for millions worldwide. However, along with these benefits come inherent risks, such as periprosthetic ...
  • Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM 
    Study Group for Infections in Critically Ill Patients of the European Society of Clinical Microbiology and Infectious Diseases (ESGCIP), the Fungal Infection Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EFISG), the European Society of Intensive Care Medicine (ESICM), the European Confederation of Medical Mycology (ECMM), the Mycoses Study Group Education and Research Consortium (MSGERC), the International Society of Antimicrobial Chemotherapy (ISAC), the International Society for Human and Animal Mycology (ISHAM), the Austrian Society for Medical Mycology (ÖGMM), the Italian Society of Anesthesia, Analgesia, Reanimation, and Intensive Care (SIAARTI), the Italian Society of Anti-Infective Therapy (SITA), and the FUNDICU Collaborators (Springer-Verlag, 2024-04)
    PURPOSE: The aim of this document was to develop standardized research definitions of invasive fungal diseases (IFD) in non-neutropenic, adult patients without classical host factors for IFD, admitted to intensive care ...
  • ECPELLA as a bridge-to-decision in refractory cardiogenic shock: a single-centre experience 
    Balder, Jan Willem; Szymanski, Mariusz K.; van Laake, Linda W.; van der Harst, Pim; Meuwese, Christiaan L.; Ramjankhan, Faiz Z.; van der Meer, Manon G.; Hermens, Jeannine A.J.M.; Voskuil, Michiel; de Waal, Eric E.C.; Donker, Dirk W.; Oerlemans, Marish I.F.J.; Kraaijeveld, Adriaan O. (Bohn Stafleu van Loghum, 2024-06)
    Background: In refractory cardiogenic shock, temporary mechanical support (tMCS) may be crucial for maintaining tissue perfusion and oxygen delivery. tMCS can serve as a bridge-to-decision to assess eligibility for left ...
  • Author Correction 2024: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials(Nature Communications, (2021), 12, (1), 10.1038/s41467-021-22446-z) 
    Axfors, Cathrine; Schmitt, Andreas M; Janiaud, Perrine; Van't Hooft, Janneke; Abd-Elsalam, Sherief; Abdo, Ehab F; Abella, Benjamin S; Akram, Javed; Amaravadi, Ravi K; Angus, Derek C; Arabi, Yaseen M; Azhar, Shehnoor; Baden, Lindsey R; Baker, Arthur W; Belkhir, Leila; Benfield, Thomas; Berrevoets, Marvin A H; Chen, Cheng-Pin; Chen, Tsung-Chia; Cheng, Shu-Hsing; Cheng, Chien-Yu; Chung, Wei-Sheng; Cohen, Yehuda Z; Cowan, Lisa N; Dalgard, Olav; de Almeida E Val, Fernando F; de Lacerda, Marcus V G; de Melo, Gisely C; Derde, Lennie; Dubee, Vincent; Elfakir, Anissa; Gordon, Anthony C; Hernandez-Cardenas, Carmen M; Hills, Thomas; Hoepelman, Andy I M; Huang, Yi-Wen; Igau, Bruno; Jin, Ronghua; Jurado-Camacho, Felipe; Khan, Khalid S; Kremsner, Peter G; Kreuels, Benno; Kuo, Cheng-Yu; Le, Thuy; Lin, Yi-Chun; Lin, Wu-Pu; Lin, Tse-Hung; Lyngbakken, Magnus Nakrem; McArthur, Colin; McVerry, Bryan J; Meza-Meneses, Patricia; Monteiro, Wuelton M; Morpeth, Susan C; Mourad, Ahmad; Mulligan, Mark J; Murthy, Srinivas; Naggie, Susanna; Narayanasamy, Shanti; Nichol, Alistair; Novack, Lewis A; O'Brien, Sean M; Okeke, Nwora Lance; Perez, Léna; Perez-Padilla, Rogelio; Perrin, Laurent; Remigio-Luna, Arantxa; Rivera-Martinez, Norma E; Rockhold, Frank W; Rodriguez-Llamazares, Sebastian; Rolfe, Robert; Rosa, Rossana; Røsjø, Helge; Sampaio, Vanderson S; Seto, Todd B; Shahzad, Muhammad; Soliman, Shaimaa; Stout, Jason E; Thirion-Romero, Ireri; Troxel, Andrea B; Tseng, Ting-Yu; Turner, Nicholas A; Ulrich, Robert J; Walsh, Stephen R; Webb, Steve A; Weehuizen, Jesper M; Velinova, Maria; Wong, Hon-Lai; Wrenn, Rebekah; Zampieri, Fernando G; Zhong, Wu; Moher, David; Goodman, Steven N; Ioannidis, John P A; Hemkens, Lars G (Nature Publishing Group, 2024-02-05)
    Correction to: Nature Communicationshttps://doi.org/10.1038/s41467-021-22446-z, published online 15 April 2021 The original version of this article contained an error in Table 1, which misidentified the trial included in ...
  • Effect of a national guideline on postoperative troponin surveillance: a retrospective cohort study 
    Alvarez Torres, Eva; Bartoszko, Justyna; Martinez Perez, Selene; Tait, Gordon; Santema, Michael; Beattie, W. Scott; McCluskey, Stuart A.; van Klei, Wilton A. (Springer New York, 2024-03)
    Purpose: We aimed to evaluate the effect of the 2017 Canadian Cardiovascular Society (CCS) guidelines on troponin surveillance after noncardiac surgery. Methods: This was a single-centre, retrospective, observational study. ...
  • Anti-inflammatory therapies are associated with delayed onset of anemia and reduction in transfusion requirements in critically ill patients: results from two studies 
    Bolscher, Madelief; Koster, Stephanie C.E.; Koopmans, Matty; Haitsma Mulier, Jelle L.G.; Derde, Lennie P.G.; Juffermans, Nicole P. (Springer Science + Business Media, 2024-04-09)
    BACKGROUND: Anemia is a hallmark of critical illness, which is largely inflammatory driven. We hypothesized that the use of anti-inflammatory agents limits the development of anemia and reduces the need for red blood cell ...