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Improved delineation with diffusion weighted imaging for laryngeal and hypopharyngeal tumors validated with pathology

Smits, Hilde J G; Raaijmakers, Cornelis P J; de Ridder, Mischa; Gouw, Zeno A R; Doornaert, Patricia A H; Pameijer, Frank A; Lodeweges, Joyce E; Ruiter, Lilian N; Kuijer, Koen M; Schakel, Tim; de Bree, Remco; Dankbaar, Jan W; Terhaard, Chris H J; Breimer, Gerben E; Willems, Stefan M; Philippens, Marielle E P (Elsevier Ireland Ltd, 2024-05)

OBJECTIVE: This study aims to determine the added value of a geometrically accurate diffusion-weighted (DW-) MRI sequence on the accuracy of gross tumor volume (GTV) delineations, using pathological tumor delineations as ...
Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment

of the PrescrAIP Study Group (W.B. Saunders, 2024-05)

Background & Aims: Autoimmune pancreatitis (AIP) is an immune-mediated disease of the pancreas with distinct pathophysiology and manifestations. Our aims were to characterize type 1 AIP in a large pan-European cohort and ...
Adherence to low-dose methotrexate in children with juvenile idiopathic arthritis using a sensitive methotrexate assay

Möhlmann, Julia E; de Roock, Sytze; Egas, Annelies C; Weijden, Evelien Ter; Doeleman, Martijn J H; Huitema, Alwin D R; van Luin, Matthijs; Swart, Joost F (BioMed Central Ltd., 2024-05-07)

BACKGROUND: Low-dose weekly methotrexate (MTX) is the mainstay of treatment in juvenile idiopathic arthritis. Unfortunately, a substantial part of patients has insufficient efficacy of MTX. A potential cause of this ...
Immunogenicity of COVID-19 booster vaccination in IEI patients and their one year clinical follow-up after start of the COVID-19 vaccination program

VACOPID Research Group (Frontiers Media S. A., 2024)

PURPOSE: Previous studies have demonstrated that the majority of patients with an inborn error of immunity (IEI) develop a spike (S)-specific IgG antibody and T-cell response after two doses of the mRNA-1273 COVID-19 ...
Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients

BioCog consortium (John Wiley & Sons Inc., 2024-04)

BACKGROUND: Structural disconnectivity was found to precede dementia. Global white matter abnormalities might also be associated with postoperative delirium (POD). METHODS: We recruited older patients (≥65 years) without ...
The Role of Multimodality Imaging (CT & MR) as a Guide to the Management of Chronic Coronary Syndromes

Working Group CT & Nuclear of the Italian Society of Cardiology (Multidisciplinary Digital Publishing Institute (MDPI), 2024-06-13)

Chronic coronary syndrome (CCS) is one of the leading cardiovascular causes of morbidity, mortality, and use of medical resources. After the introduction by international guidelines of the same level of recommendation to ...
Infectious Diseases and Basal Ganglia Calcifications: A Cross-Sectional Study in Patients with Fahr's Disease and Systematic Review

Snijders, Birgitta M G; Peters, Mike J L; van den Brink, Susanne; van Trijp, Marijke J C A; de Jong, Pim A; Vissers, Laurens A T M; Verduyn Lunel, Frans M; Emmelot-Vonk, Marielle H; Koek, Huiberdina L (Multidisciplinary Digital Publishing Institute (MDPI), 2024-04-02)

Background: It is unclear whether patients with basal ganglia calcifications (BGC) should undergo infectious disease testing as part of their diagnostic work-up. We investigated the occurrence of possibly associated ...
The effect of subcutaneous and sublingual birch pollen immunotherapy on birch pollen–related food allergy: a systematic review

Kallen, E. J.J.; Welsing, P. M.J.; Löwik, J. M.; Van Ree, R.; Knulst, A. C.; Le, T. M. (Frontiers Media S. A., 2024)

Background: Birch pollen–related food allergy (BPFA) is the most common type of food allergy in birch-endemic areas such as Western and Central Europe. Currently, there is no treatment available for BPFA. Due to the ...
Exploring patients' experience using PROMs within routine post-discharge follow-up assessment after stroke: a mixed methods approach

Mourits, B M P; den Hartog, S J; Roozenbeek, B; Post, M W M; Visser-Meily, J M A; Scholten, E W M (Springer International Publishing AG, 2024-04-26)

BACKGROUND: Patient Reported Outcomes Measures (PROMs) are being used increasingly to measure health problems in stroke clinical practice. However, the implementation of these PROMs in routine stroke care is still in its ...
Meta-analysis of epigenetic aging in schizophrenia reveals multifaceted relationships with age, sex, illness duration, and polygenic risk

Ori, Anil P.S.; Olde Loohuis, Loes M.; Guintivano, Jerry; Hannon, Eilis; Dempster, Emma; St. Clair, David; Bass, Nick J.; McQuillin, Andrew; Mill, Jonathan; Sullivan, Patrick F.; Kahn, Rene S.; Horvath, Steve; Ophoff, Roel A. (Springer-Verlag, 2024-04-08)

Background: The study of biological age acceleration may help identify at-risk individuals and reduce the rising global burden of age-related diseases. Using DNA methylation (DNAm) clocks, we investigated biological aging ...
CXCL10 is a crucial chemoattractant for efficient intranasal delivery of mesenchymal stem cells to the neonatal hypoxic-ischemic brain

Hermans, Eva C.; Donega, Vanessa; Heijnen, Cobi J.; de Theije, Caroline G.M.; Nijboer, Cora H. (BioMed Central, 2024-05-07)

Background: Hypoxic-Ischemic Encephalopathy (HIE) is a leading cause of mortality and morbidity in newborns. Recent research has shown promise in using intranasal mesenchymal stem cell (MSC) therapy if administered within ...
Orthostatic hypotension, cognition and structural brain imaging in hemodynamically impaired patients

Starmans, Naomi L.P.; Wolters, Frank J.; Leeuwis, Anna E.; Bron, Esther E.; de Bresser, Jeroen; Brunner-La Rocca, Hans Peter; Staals, Julie; Muller, Majon; Biessels, Geert Jan; Kappelle, L. Jaap; on behalf of the Heart-Brain Connection Consortium (Elsevier, 2024-06-15)

Background: Orthostatic hypotension (OH) is associated with an increased risk of dementia, potentially attributable to cerebral hypoperfusion. We investigated which patterns and characteristics of OH are related to cognition ...
Mechanosensing regulates tissue repair program in macrophages

Meizlish, Matthew L.; Kimura, Yoshitaka; Pope, Scott D.; Matta, Rita; Kim, Catherine; Philip, Naomi H.; Meyaard, Linde; Gonzalez, Anjelica; Medzhitov, Ruslan (American Association for the Advancement of Science, 2024-03)

Tissue-resident macrophages play important roles in tissue homeostasis and repair. However, how macrophages monitor and maintain tissue integrity is not well understood. The extracellular matrix (ECM) is a key structural ...
Alzheimer's Disease and Cognitive Decline in Patients with Cardiovascular Diseases Along the Heart-Brain Axis

Trieu, Calvin; van Harten, Argonde C.; Leeuwis, Anna E.; Exalto, Lieza G.; Hooghiemstra, Astrid M.; Verberk, Inge M.W.; Allaart, Cor P.; Brunner-La Rocca, Hans Peter; Kappelle, L. Jaap; van Oostenbrugge, Robert J.; Biessels, Geert Jan; Teunissen, Charlotte E.; van der Flier, Wiesje M.; Heart-Brain Connection Consortium (IOS Press, 2024-04-02)

Background: We hypothesize that Alzheimer's disease (AD)-related pathology may accelerate cognitive decline in patients with cardiovascular diseases. Objective: To investigate the association between blood-based biomarkers ...
MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway: Role in lateral ventricles and corpus callosum volume

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands (GJB, GJER) (Elsevier, 2024-04-01)

Background/Objective. Enlarged lateral ventricle (LV) volume and decreased volume in the corpus callosum (CC) are hallmarks of schizophrenia (SZ). We previously showed an inverse correlation between LV and CC volumes in ...
Response to psychotic experiences: Impact of personality traits on perceived levels of distress

Group (Elsevier, 2024-05)

Background: This study examined the influence of personality traits on (subclinical) positive symptom distress in patients with a psychotic disorder, their unaffected siblings and healthy controls. Methods: Data were ...
Correction to:: Comparative effectiveness of β-lactams for empirical treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a prospective cohort study (Journal of Antimicrobial Chemotherapy DOI: 10.1093/jac/dkad057)

Buis, D T P; van der Vaart, T W; Prins, J M; van der Meer, J T M; Bonten, M J M; Sieswerda, E; van Werkhoven, C H; Sigaloff, K C E (Oxford University Press, 2024-02-01)

To our regret we realized that the following error was present in multivariable analyses, neither cefuroxime nor ceftriaxone was the original published version of this article: In the Abstract, associated with increased ...
USP27X variants underlying X-linked intellectual disability disrupt protein function via distinct mechanisms

Koch, Intisar; Slovik, Maya; Zhang, Yuling; Liu, Bingyu; Rennie, Martin; Konz, Emily; Cogne, Benjamin; Daana, Muhannad; Davids, Laura; Diets, Illja J; Gold, Nina B; Holtz, Alexander M; Isidor, Bertrand; Mor-Shaked, Hagar; Neira Fresneda, Juanita; Niederhoffer, Karen Y; Nizon, Mathilde; Pfundt, Rolph; Simon, Meh; Stegmann, Apa; Guillen Sacoto, Maria J; Wevers, Marijke; Barakat, Tahsin Stefan; Yanovsky-Dagan, Shira; Atanassov, Boyko S; Toth, Rachel; Gao, Chengjiang; Bustos, Francisco; Harel, Tamar (Life Science Alliance, LLC, 2024-01-05)

Neurodevelopmental disorders with intellectual disability (ND/ID) are a heterogeneous group of diseases driving lifelong deficits in cognition and behavior with no definitive cure. X-linked intellectual disability disorder ...
Risk mapping of respiratory viral transmission and disease severity using individual and environmental health parameters: A scoping review and protocol analysis

Niese, Rebecca; van der Vlist, Dominique; Verhagen, Mark; de Haan, Noortje; Stunnenberg, Melissa; Serafim, Fábio; Kretzschmar, Mirjam; van der Wal, Annemieke; Vermeulen, Lucie; Tholen, Aletta; de Roda Husman, Ana Maria (Elsevier, 2024-06)

Due to the impact respiratory viruses have on human health, a lot of data has been collected and visualised in tools such as dashboards that provide retrospective insights into the course of an epidemic or pandemic. Two ...
Minocycline in Severe Cerebral Amyloid Angiopathy: A Single-Center Cohort Study

Bax, Francesco; Warren, Andrew; Fouks, Avia Abramovitz; van den Brink, Hilde; van Veluw, Susanne J; Kozberg, Mariel G; Greenberg, Steven M (Wiley-Blackwell, 2024-02-20)

BACKGROUND: Evidence from animal studies suggests that minocycline may reduce lobar intracerebral hemorrhage (ICH) recurrence in cerebral amyloid angiopathy, possibly by inhibiting perivascular extracellular matrix degradation ...

Now showing items 6821-6840 of 40729