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Now showing items 6841-6860 of 40729

Type 1 VWD classification revisited - novel insights from combined analysis of the LoVIC and WiN studies

Atiq, Ferdows; Blok, Robin; van Kwawegen, Calvin; Doherty, Dearbhla; Lavin, Michelle; van der Bom, Johanna G; O'Connell, Niamh M; de Meris, Joke; Ryan, Kevin; Schols, Saskia E M; Byrne, Mary B; Heubel-Moenen, Floor C J I; van Galen, Karin P M; Preston, Roger J S; Cnossen, Marjon H; Fijnvandraat, Karin; Baker, Ross Ian; Meijer, Karina; James, Paula D; Di Paola, Jorge; Eikenboom, Jeroen C J; Leebeek, Frank W G; O'Donnell, James S (Elsevier, 2024-04-04)

There is significant ongoing debate regarding type 1 von Willebrand disease (VWD) defintion. Previous guidelines recommended patients with von Willebrand factor (VWF) levels <30 IU/dL be diagnosed type 1 VWD, whereas ...
Regional patient transfer patterns matter for the spread of hospital-acquired pathogens

Xia, Hanjue; Horn, Johannes; Piotrowska, Monika J.; Sakowski, Konrad; Karch, André; Kretzschmar, Mirjam; Mikolajczyk, Rafael (Nature Publishing Group, 2024-01-09)

Pathogens typically responsible for hospital-acquired infections (HAIs) constitute a major threat to healthcare systems worldwide. They spread via hospital (or hospital-community) networks by readmissions or patient ...
Memory B-cell derived donor-specific antibodies do not predict outcome in sensitized kidney transplant recipients: a retrospective single-center study

Altulea, Dania; van den Born, Joost C.; Diepstra, Arjan; Bungener, Laura; Terpstra, Dagmar; Hepkema, Bouke G.; Lammerts, Rosa; Heeringa, Peter; Heidt, Sebastiaan; Otten, Henny; Reteig, Leon; Karahan, Gonca E.; Berger, Stefan P.; Sanders, Jan Stephan (Frontiers Media S. A., 2024-04-05)

Background: Repeated exposure to sensitizing events can activate HLA-specific memory B cells, leading to the production of donor-specific memory B cell antibodies (DSAm) that pose a risk for antibody-mediated rejection ...
Looking beyond Body Structure and Function: ICF Foci and Who Is Being Assessed in Research about Adolescents and Young Adults with Cerebral Palsy-A Scoping Review

Santana, Camila Araújo Santos; Rosenbaum, Peter; van der Kemp, Jet; de Campos, Ana Carolina (Multidisciplinary Digital Publishing Institute (MDPI), 2024-06)

PURPOSE: The purpose of this study is to summarize the ICF foci, looking beyond body structures and function, and to analyze who has been assessed in research about adolescents and young adults (AYAs) with CP in the phase ...
Bipolar symptoms, somatic burden and functioning in older-age bipolar disorder: A replication study from the global aging & geriatric experiments in bipolar disorder database (GAGE-BD) project

Sajatovic, Martha; Rej, Soham; Almeida, Osvaldo P; Altinbas, Kursat; Balanzá-Martínez, Vicent; Barbosa, Izabela G; Beunders, Alexandra J M; Blumberg, Hilary P; Briggs, Farren B S; Dols, Annemiek; Forester, Brent P; Forlenza, Orestes V; Gildengers, Ariel G; Jimenez, Esther; Klaus, Federica; Lafer, Beny; Mulsant, Benoit; Mwangi, Benson; Nunes, Paula Villela; Olagunju, Andrew T; Oluwaniyi, Stephen; Orhan, Melis; Patrick, Regan E; Radua, Joaquim; Rajji, Tarek; Sarna, Kaylee; Schouws, Sigfried; Simhandl, Christian; Sekhon, Harmehr; Soares, Jair C; Sutherland, Ashley N; Teixeira, Antonio L; Tsai, Shangying; Vidal-Rubio, Sonia; Vieta, Eduard; Yala, Joy; Eyler, Lisa T (John Wiley & Sons Inc., 2024-03)

Objectives: The Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE-BD) project pools archival datasets on older age bipolar disorder (OABD). An initial Wave 1 (W1; n = 1369) analysis found both manic ...
The Utrecht University Honours Program review project: example based scientific publishing training aimed at bachelor medical students

Bloothooft, Meye; Pennings, Helena J.M.; van der Heyden, Marcel A.G. (BioMed Central, 2024-02-06)

Introduction: Medical undergraduate students receive limited education on scholarly publishing. However, publishing experiences during this phase are known to influence study and career paths. The medical bachelor Honours ...
Reduced uterine perfusion pressure as a model for preeclampsia and fetal growth restriction in murine: a systematic review and meta-analysis

van Kammen, Caren M; Taal, Seija E L; Wever, Kimberley E; Granger, Joey P; Lely, A Titia; Terstappen, Fieke (American Physiological Society, 2024-05)

The reduced uterine perfusion pressure (RUPP) model is frequently used to study preeclampsia and fetal growth restriction. An improved understanding of influential factors might improve reproducibility and reduce animal ...
Potential merits and flaws of large language models in epilepsy care: A critical review

van Diessen, Eric; van Amerongen, Ramon A.; Zijlmans, Maeike; Otte, Willem M. (Wiley-Blackwell, 2024-04)

The current pace of development and applications of large language models (LLMs) is unprecedented and will impact future medical care significantly. In this critical review, we provide the background to better understand ...
The endometrial transcriptome of infertile women with and without implantation failure

Bui, Bich Ngoc; Kukushkina, Viktorija; Meltsov, Alvin; Olsen, Catharina; van Hoogenhuijze, Nienke; Altmäe, Signe; Mol, Femke; Teklenburg, Gijs; de Bruin, Jan-Peter; Besselink, Dagmar; Stevens Brentjens, Linda; Obukhova, Darina; Zamani Esteki, Masoud; van Golde, Ron; Romano, Andrea; Laisk, Triin; Steba, Gaby; Mackens, Shari; Salumets, Andres; Broekmans, Frank (Wiley-Blackwell, 2024-07)

INTRODUCTION: Implantation failure after transferring morphologically "good-quality" embryos in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) may be explained by impaired endometrial receptivity. ...
Healthcare costs related to respiratory syncytial virus in paediatric intensive care units in the Netherlands: a nationwide prospective observational study (the BRICK study)

Phijffer, Emily W.E.M.; Wildenbeest, Joanne G.; Brouwer, Carole N.M.; de Hoog, Matthijs; Kneyber, Martin C.J.; Maebe, Sofie; Nusmeier, Anneliese; Riedijk, Maaike A.; Wösten-van Asperen, Roelie M.; van Woensel, Job B.M.; Bont, Louis J.; Frederix, Geert J.W. (Elsevier, 2024-08)

Background: The implementation of the approved respiratory syncytial virus (RSV) preventive interventions in immunisation programmes is advancing rapidly. Insight into healthcare costs of RSV-related paediatric intensive ...
Surgical Techniques and Related Perioperative Outcomes After Robot-assisted Minimally Invasive Gastrectomy (RAMIG): Results From the Prospective Multicenter International Ugira Gastric Registry

UGIRA Collaborative Group (Lippincott Williams & Wilkins, 2024-07-01)

OBJECTIVE: To gain insight into the global practice of robot-assisted minimally invasive gastrectomy (RAMIG) and evaluate perioperative outcomes using an international registry. BACKGROUND: The techniques and perioperative ...
Extrahepatic perfusion and incomplete hepatic perfusion after hepatic arterial infusion pump implantation: incidence and clinical implications

Dutch HAIP consortium (John Wiley & Sons Inc., 2024-07)

Introduction: This study investigates the incidence of extrahepatic perfusion and incomplete hepatic perfusion at intraoperative methylene blue testing and on postoperative nuclear imaging in patients undergoing hepatic ...
On Patient Experience and Anxiety During Treatment With Magnetic Resonance–Guided Radiation Therapy

Westerhoff, Jasmijn M.; Borman, Pim T.S.; Rutgers, Reijer H.A.; Raaymakers, Bas W.; Winchester, Neil; Verkooijen, Helena M.; Fast, Martin F. (Elsevier, 2024-08)

Purpose: To assess patient experience and anxiety during magnetic resonance (MR)–guided radiation therapy (MRgRT) using a hybrid 1.5Tesla (T) MR-guided linear accelerator (MR-Linac) when offered calming video content. ...
The Value of Warning Signs From the WHO 2009 Dengue Classification in Detecting Severe Dengue in Children

Karyanti, Mulya Rahma; Uiterwaal, Cuno S P M; Hadinegoro, Sri Rezeki; Widyahening, Indah Suci; Saldi, Siti Rizny F; Heesterbeek, J A P Hans; Hoes, Arno W; Bruijning-Verhagen, Patricia (Lippincott Williams & Wilkins, 2024-07-01)

BACKGROUND: World Health Organization proposed 7 warning signs to identify the risk of severe dengue in 2009. This study aimed to evaluate the value of these warning signs in detecting severe dengue in children. MATERIAL ...
Age Trajectories of the Structural Connectome in Child and Adolescent Offspring of Individuals With Bipolar Disorder or Schizophrenia

Poortman, Simon R.; Barendse, Marjolein E.A.; Setiaman, Nikita; van den Heuvel, Martijn P.; de Lange, Siemon C.; Hillegers, Manon H.J.; van Haren, Neeltje E.M. (Elsevier, 2024-09)

Background: Offspring of parents with severe mental illness (e.g., bipolar disorder or schizophrenia) are at elevated risk of developing psychiatric illness owing to both genetic predisposition and increased burden of ...
Relationship of neutrophil-to-lymphocyte ratio, in addition to C-reactive protein, with cardiovascular events in patients with type 2 diabetes

Hoes, Lukas L.F.; Riksen, Niels P.; Geleijnse, Johanna M.; de Groot, Mark C.H.; T. van der Schouw, Yvonne; Visseren, Frank L.J.; Koopal, Charlotte (Elsevier Ireland Ltd, 2024-07)

Aim: To quantify the relationship of neutrophil-to-lymphocyte ratio (NLR) with cardiovascular events and all-cause mortality in patients with type 2 diabetes (T2D), independent of C-reactive protein (CRP). Methods: Patients ...
Integration of pathological criteria and immunohistochemical evaluation for invasive lobular carcinoma diagnosis: recommendations from the European Lobular Breast Cancer Consortium

Pathology Working group of the European Lobular Breast Cancer Consortium (Elsevier, 2024-07)

Invasive lobular carcinoma (ILC) is the second most frequent type of breast cancer (BC) and its peculiar morphology is mainly driven by inactivation of CDH1, the gene coding for E-cadherin cell adhesion protein. ILC-specific ...
Intervention strategies to improve adherence to treatment for selected chronic conditions in sub-Saharan Africa: a systematic review

Gumede, Siphamandla Bonga; de Wit, John B.F.; Venter, Willem D.F.; Wensing, Annemarie M.J.; Lalla-Edward, Samanta Tresha (International AIDS Society, 2024-06)

Introduction: Evidence-based intervention strategies to improve adherence among individuals living with chronic conditions are critical in ensuring better outcomes. In this systematic review, we assessed the impact of ...
Advancing drug development for atrial fibrillation by prioritising findings from human genetic association studies

Kukendrarajah, Kishore; Farmaki, Aliki Eleni; Lambiase, Pier D.; Schilling, Richard; Finan, Chris; Floriaan Schmidt, Amand; Providencia, Rui (Elsevier, 2024-07)

Background: Drug development for atrial fibrillation (AF) has failed to yield new approved compounds. We sought to identify and prioritise potential druggable targets with support from human genetics, by integrating the ...
Safety and efficacy of Holmium-166 selective internal radiotherapy of primary and secondary liver cancer confirmed by real-world data

Schulze-Zachau, Victor; Verset, Gontran; De Bondt, Pieter; De Keukeleire, Katrien; Gühne, Falk; Heuschkel, Martin; Hoffmann, Ralf Thorsten; Bozzi, Elena; Sciuto, Rosa; Lam, Marnix; Deportós Moreno, Jordi; Debrus, Roxane; Zech, Christoph J. (Frontiers Media S. A., 2024-06-11)

Purpose: Holmium-166 has emerged as a promising option for selective internal radiotherapy (SIRT) for hepatic malignancies, but data on routine clinical use are lacking. The purpose of this study was to describe the safety ...

Now showing items 6841-6860 of 40729