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Fibroblasts as an in vitro model of circadian genetic and genomic studies

Francia, Marcelo; Bot, Merel; Boltz, Toni; De la Hoz, Juan F; Boks, Marco; Kahn, René S; Ophoff, Roel A (Springer New York, 2024-09)

Bipolar disorder (BD) is a heritable disorder characterized by shifts in mood that manifest in manic or depressive episodes. Clinical studies have identified abnormalities of the circadian system in BD patients as a hallmark ...
Views of family members on using video calls during the hospital admission of a patient: A qualitative study

in de Braekt, Anna; Coolen, Celeste M.; Maaskant, Jolanda M.; de Man-van Ginkel, Janneke M.; Eskes, Anne M.; Jongerden, Irene P. (Wiley-Blackwell, 2024-09)

Background: Utilization of video calls on hospital wards to facilitate involvement of and communication with family members is still limited. A deeper understanding of the needs and expectations of family members regarding ...
Individual outcomes after tailored versus generic self-management strategies for persistent fatigue in youth with a fatigue syndrome or rheumatic condition: A multiple single-case study

Vroegindeweij, Anouk; Houtveen, Jan; Lucassen, Desiree A; Van De Putte, Elise M; Wulffraat, Nico M; Nijhof, Sanne L; Swart, Joost F (Wiley-Blackwell, 2024-09)

Objective: To examine individual outcomes after tailored lifestyle (PROfeel) or generic dietary advice as self-management intervention for persistent fatigue in adolescents and young adults with a chronic condition, to ...
HbA1cand fasting plasma glucose levels are equally related to incident cardiovascular risk in a high CVD risk population without known diabetes

Been, Riemer A.; Noordstar, Ellen; Helmink, Marga A.G.; Van Sloten, Thomas T.; De Ranitz-Greven, Wendela L.; Van Beek, André P.; Houweling, Sebastiaan T.; Van Dijk, Peter R.; Westerink, Jan (Walter de Gruyter, 2024-08-01)

Objectives: Type 2 diabetes (T2DM) is associated with increased risk for cardiovascular disease (CVD). Whether screen-detected T2DM, based on fasting plasma glucose (FPG) or on HbA1c, are associated with different risks ...
The Diagnostic Accuracy of Serum Alpha-Fetoprotein Levels in Follow-up for Recurrence of Sacrococcygeal Teratoma; a Nationwide Review of SCT Cases in the Netherlands

van Heurn, Lieke J.; Kremer, Marijke E.B.; de Blaauw, Ivo; van Baren, Robertine; van Gemert, Wim G.; van Goudoever, Johannes B.; Sloots, Cornelius E.J.; Witvliet, Marieke J.; Ernest van Heurn, L. W.; Derikx, Joep P.M. (W.B. Saunders, 2024-09)

Background: Serum alpha-fetoprotein (AFP) is often used as tumour marker for recurrent sacrococcygeal teratoma (SCT). We aimed to assess the normal dynamics of serum AFP levels after initial resection and diagnostic accuracy ...
Sodium-Glucose Cotransporter 2 Therapy for Acute Organ Dysfunction in Critically Ill Patients

Gómez, Hernando; Derde, Lennie P.G. (American Medical Association, 2024-08-06)
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

International Childhood Cancer Outcome Project participants (Nature Research, 2024-07)
Online speech synthesis using a chronically implanted brain-computer interface in an individual with ALS

Angrick, Miguel; Luo, Shiyu; Rabbani, Qinwan; Candrea, Daniel N; Shah, Samyak; Milsap, Griffin W; Anderson, William S; Gordon, Chad R; Rosenblatt, Kathryn R; Clawson, Lora; Maragakis, Nicholas; Tenore, Francesco V; Fifer, Matthew S; Hermansky, Hynek; Ramsey, Nick F; Crone, Nathan E (medRxiv, 2023-07-01)

Recent studies have shown that speech can be reconstructed and synthesized using only brain activity recorded with intracranial electrodes, but until now this has only been done using retrospective analyses of recordings ...
A click-based electrocorticographic brain-computer interface enables long-term high-performance switch-scan spelling

Crone, Nathan; Candrea, Daniel; Shah, Samyak; Luo, Shiyu; Angrick, Miguel; Rabbani, Qinwan; Coogan, Christopher; Milsap, Griffn; Nathan, Kevin; Wester, Brock; Anderson, William; Rosenblatt, Kathryn; Clawson, Lora; Maragakis, Nicholas; Vansteensel, Mariska; Tenore, Francesco; Ramsey, Nick; Fifer, Matthew; Uchil, Alpa (Research Square, 2023-09-25)

BACKGROUND: Brain-computer interfaces (BCIs) can restore communication in movement- and/or speech-impaired individuals by enabling neural control of computer typing applications. Single command "click" decoders provide a ...
Considerations for implanting speech brain computer interfaces based on functional magnetic resonance imaging

Guerreiro Fernandes, F; Raemaekers, M; Freudenburg, Z; Ramsey, N (IOP Publishing Ltd., 2024-06-01)

Objective.Brain-computer interfaces (BCIs) have the potential to reinstate lost communication faculties. Results from speech decoding studies indicate that a usable speech BCI based on activity in the sensorimotor cortex ...
Continuous Development of a Major Incident In-Hospital Victim Tracking and Tracing System, Withstanding the Challenges of Time

Haverkort, J J Mark; Bouman, Jos H; Wind, Jelte D D; Leenen, Luke P H (Cambridge University Press, 2017-02)

OBJECTIVE: To describe the development of the Patient Barcode Registration System (PBRS) over time and confirm the usability and feasibility of the system's latest version during a large trauma drill. METHODS: The development ...
Morphology and genetics of pyloric gland adenomas in familial adenomatous polyposis

Hackeng, Wenzel M.; Montgomery, Elizabeth A.; Giardiello, Francis M.; Singhi, Aatur D.; Debeljak, Marija; Eshleman, James R.; Vieth, Michael; Offerhaus, G. Johan; Wood, Laura D.; Brosens, Lodewijk A A (Wiley-Blackwell, 2017-03)

Aims: Gastric pyloric gland adenomas (PGAs) are rare epithelial polyps that are found more commonly in autoimmune atrophic gastritis and familial adenomatous polyposis (FAP). Little is known about the morphology and genetics ...
Temporal shifts in clinical presentation and underlying mechanisms of atherosclerotic disease

Pasterkamp, Gerard; den Ruijter, Hester M.; Libby, Peter (Nature Research, 2017-01)

The concept of the 'vulnerable plaque' originated from pathological observations in patients who died from acute coronary syndrome. This recognition spawned a generation of research that led to greater understanding of how ...
Time matters: adenosine testing immediately after pulmonary vein isolation does not substitute a waiting period

Teunissen, Cas; Clappers, Nick; Kassenberg, W; Hassink, RJ; van der Heijden, JF; Loh, KP (Oxford University Press, 2017-07)

Aims Adenosine testing can reveal dormant pulmonary vein (PV) conduction after PV antrum isolation (PVAI). However, the optimal timing for adenosine administration is unknown. We hypothesized that adenosine testing immediately ...
Variation in the CTLA4 3′UTR has phenotypic consequences for autoreactive T cells and associates with genetic risk for type 1 diabetes

de Jong, V. M.; Zaldumbide, A.; van der Slik, A. R.; Laban, S.; Koeleman, B. P C; Roep, B. O. (Springer Nature, 2016)

Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) is a protein receptor that downregulates the immune system. CTLA4 gene variants associate with various autoimmune diseases, including type 1 diabetes. Fine mapping of the ...
Chondrogenesis by bone marrow-derived mesenchymal stem cells grown in chondrocyte-conditioned medium for auricular reconstruction

Zhao, Xing; Hwang, Nathaniel S; Bichara, David A; Saris, Daniel B; Malda, J; Vacanti, Joseph P; Pomerantseva, Irina; Sundback, Cathryn A; Langer, Robert; Anderson, Daniel G; Randolph, Mark A (John Wiley & Sons Inc., 2017-10)

Bone marrow-derived mesenchymal stem cells (BMSCs) can be obtained by minimally invasive means and would be a favourable source for cell-based cartilage regeneration. However, controlling the differentiation of the BMSCs ...
Updated European Association of Urology Guidelines Regarding Adjuvant Therapy for Renal Cell Carcinoma

Bex, Axel; Albiges, Laurence; Ljungberg, Börje; Bensalah, Karim; Dabestani, Saeed; Giles, Rachel H; Hofmann, Fabian; Hora, Milan; Kuczyk, Markus A; Lam, Thomas B; Marconi, Lorenzo; Merseburger, Axel S; Staehler, Michael; Volpe, Alessandro; Powles, Thomas (Elsevier, 2017-05)

The European Association of Urology Renal Cell Carcinoma (RCC) guidelines panel updated their recommendation on adjuvant therapy in unfavourable, clinically nonmetastatic RCC following the recently reported results of a ...
Diagnostic strategy and timing of intervention in infected necrotizing pancreatitis: An international expert survey and case vignette study

van Grinsven, Janneke; van Brunschot, Sandra; Bakker, Olaf J.; Bollen, Thomas L.; Boermeester, Marja A.; Bruno, Marco J.; Dejong, Cornelis H.; Dijkgraaf, Marcel G.; van Eijck, Casper H.; Fockens, Paul; van Goor, Harry; Gooszen, Hein G.; Horvath, Karen D.; van Lienden, Krijn P.; van Santvoort, Hjalmar C.; Besselink, Marc G. (John Wiley & Sons Inc., 2016-01)

Background: The optimal diagnostic strategy and timing of intervention in infected necrotizing pancreatitis are subject to debate. A survey was performed on these topics amongst a group of international expert pancreatologists. ...
Pharmacogenomics of inhaled corticosteroids and leukotriene modifiers: A systematic review

Farzan, N.; Vijverberg, S. J H; Arets, H. G.; Raaijmakers, J. A M; Maitland-van der Zee, A. H. (Wiley-Blackwell, 2017-02)

Background: Pharmacogenetics studies of anti-inflammatory medication of asthma have expanded rapidly in recent decades, but the clinical value of their findings remains limited. Objective: To perform a systematic review ...
An MRI Von Economo - Koskinas atlas

Scholtens, Lianne H; de Reus, Marcel A; de Lange, Siemon C; Schmidt, Ruben; van den Heuvel, Martijn P (Academic Press Inc., 2018-04-15)

The cerebral cortex displays substantial variation in cellular architecture, a regional patterning that has been of great interest to anatomists for centuries. In 1925, Constantin von Economo and George Koskinas published ...

Now showing items 5261-5280 of 40729