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Comparison of Two Generations of Thoracic Aortic Stent Grafts and Their Impact on Aortic Stiffness in an Ex Vivo Porcine Model

Mandigers, Tim J.; Conti, Michele; Allievi, Sara; Dedola, Francesca; Bissacco, Daniele; Bianchi, Daniele; Marconi, Stefania; Domanin, Maurizio; Van Herwaarden, Joost A.; Auricchio, Ferdinando; Trimarchi, Santi (Elsevier Limited, 2023-01)

Objective: Little is known about the cardiovascular changes after TEVAR and regarding the impact on aortic stiffness for different stent graft generations specifically, following changes in device design. The present study ...
Three-Dimensional Characterization of Aortic Root Motion by Vascular Deformation Mapping

Kim, Taeouk; Tjahjadi, Nic S.; He, Xuehuan; van Herwaarden, J. A.; Patel, Himanshu J.; Burris, Nicholas S.; Figueroa, C. Alberto (Multidisciplinary Digital Publishing Institute (MDPI), 2023-07)

The aorta is in constant motion due to the combination of cyclic loading and unloading with its mechanical coupling to the contractile left ventricle (LV) myocardium. This aortic root motion has been proposed as a marker ...
Editor's Choice – Comparison of the Reproducibility of Ultrasound Calliper Placement Methods in Abdominal Aortic Diameter Measurements: A Systematic Review and Meta-Analysis of Diagnostic Test Accuracy Studies

Bissacco, Daniele; Mandigers, Tim J.; Savaré, Laura; Domanin, Maurizio; D'Oria, Mario; Ieva, Francesca; Van Herwaarden, Joost A.; Mani, Kevin; Wanhainen, Anders; Trimarchi, Santi (W.B. Saunders Ltd, 2023-11)

Objective: To assess which ultrasound (US) method of maximum anteroposterior (AP) abdominal aortic diameter measurement can be considered most reproducible. Data sources: MEDLINE, Scopus, and Web of Science were searched ...
Noise-robust fixation detection in eye movement data: Identification by two-means clustering (I2MC)

Hessels, Roy S.; Niehorster, Diederick C.; Kemner, Chantal; Hooge, Ignace T C (Springer Nature, 2017-10)

Eye-tracking research in infants and older children has gained a lot of momentum over the last decades. Although eye-tracking research in these participant groups has become easier with the advance of the remote eye-tracker, ...
Topological organization of connectivity strength in the rat connectome

van Den Heuvel, Martijn P.; Scholtens, Lianne H.; de Reus, Marcel A. (Springer-Verlag, 2016)

The mammalian brain is a complex network of anatomically interconnected regions. Animal studies allow for an invasive measurement of the connections of these networks at the macroscale level by means of neuronal tracing ...
Standardisation of labial salivary gland histopathology in clinical trials in primary Sjögren's syndrome

Fisher, Benjamin A.; Jonsson, Roland; Daniels, Troy; Bombardieri, Michele; Brown, Rachel M.; Morgan, Peter; Bombardieri, Stefano; Ng, Wan Fai; Tzioufas, Athanasios G.; Vitali, Claudio; Shirlaw, Pepe; Haacke, Erlin; Costa, Sebastian; Bootsma, Hendrika; Devauchelle-Pensec, Valerie; Radstake, Timothy R.; Mariette, Xavier; Richards, Andrea; Stack, Rebecca; Bowman, Simon J.; Barone, Francesca (Elsevier, 2017-07)

Labial salivary gland (LSG) biopsy is used in the classification of primary Sjögren's syndrome (PSS) and in patient stratification in clinical trials. It may also function as a biomarker. The acquisition of tissue and ...
Executive functioning and its relation to ASD and ADHD symptomatology in 22q11.2 deletion syndrome*

Hidding, Elske; de Sonneville, Leo M J; Vorstman, Jacob A S; Sijmens-Morcus, Monique E J; Swaab, Hanna (Taylor and Francis Ltd., 2018-01)

Children with 22q11.2 deletion syndrome (22q11DS; velo-cardio-facial-syndrome) are at risk for the developmental disorders, attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). In this study, ...
cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): A new initiative in advancing nervous system tumor classification

Louis, David N.; Aldape, Ken; Brat, Daniel J.; Capper, David; Ellison, David W.; Hawkins, Cynthia; Paulus, Werner; Perry, Arie; Reifenberger, Guido; Figarella-Branger, Dominique; Wesseling, Pieter; Batchelor, Tracy T.; Gregory Cairncross, J.; Pfister, Stefan M.; Rutkowski, Stefan; Weller, Michael; Wick, Wolfgang; von Deimling, Andreas (Wiley-Blackwell, 2017-11)
Utilizing numerical simulations to prevent stent graft kinking during thoracic endovascular aortic repair

Mandigers, Tim J.; Ramella, Anna; Bissacco, Daniele; Domanin, Maurizio; van Herwaarden, Joost A.; Luraghi, Giulia; Migliavacca, Francesco; Trimarchi, Santi (2023-09)

Numerical simulations of thoracic endovascular aortic repair (TEVAR) may be implemented in the preoperative workflow if credible and reliable. We present the application of a TEVAR simulation methodology to an 82-year-old ...
Mannose-binding lectin and l-ficolin polymorphisms in patients with community-acquired pneumonia caused by intracellular pathogens

van Kempen, Gijs; Meijvis, Sabine; Endeman, Henrik; Vlaminckx, Bart; Meek, Bob; de Jong, Ben; Rijkers, Ger; Bos, Willem Jan (Wiley-Blackwell, 2017-05)

Community-acquired pneumonia (CAP) is the leading infectious disease requiring hospitalization in the western world. Genetic variability affecting the host response to infection may play a role in susceptibility and outcome ...
What to expect and when to expect it: an fMRI study of expectancy in children with ADHD symptoms

van Hulst, Branko M; de Zeeuw, Patrick; Rijks, Yvonne; Neggers, Sebastiaan F W; Durston, Sarah (Springer Science and Business Media Deutschland GmbH, 2017)

Changes in cognitive control and timing have both been implicated in ADHD. Both are involved in building and monitoring expectations about the environment, and altering behavior if those expectations are violated. In ADHD, ...
Changes in White Matter Organization in Adolescent Offspring of Schizophrenia Patients

de Leeuw, Max; Bohlken, Marc M.; Mandl, René CW; Hillegers, Manon HJ; Kahn, René S.; Vink, Matthijs (Springer Nature, 2017-01-01)

Schizophrenia is associated with frontostriatal network impairments underlying clinical and cognitive symptoms. We previously found disruptions in anatomical pathways, including the tract connecting the left nucleus accumbens ...
Low Rate of Dysplasia Detection in Mucosa Surrounding Dysplastic Lesions in Patients Undergoing Surveillance for Inflammatory Bowel Diseases

Ten Hove, J R; Mooiweer, E; Dekker, E; van der Meulen-de Jong, A E; Offerhaus, G J A; Ponsioen, C Y; Siersema, P D; Oldenburg, B (W.B. Saunders, 2017-02)

Background & Aims When dysplastic lesions are encountered during surveillance colonoscopy of patients with inflammatory bowel disease (IBD), guidelines recommend collection of additional biopsies from the surrounding mucosa ...
Clinical implications of low grade dysplasia found during inflammatory bowel disease surveillance: a retrospective study comparing chromoendoscopy and white-light endoscopy

Ten Hove, Joren R; Mooiweer, Erik; van der Meulen de Jong, Andrea E; Dekker, Evelien; Ponsioen, Cyriel Y; Siersema, Peter D; Oldenburg, Bas (Georg Thieme Verlag, 2017)

Background and study aims: Current guidelines recommend the use of pancolonic chromoendoscopy for surveillance of patients with inflammatory bowel disease (IBD). It is currently unknown whether low grade dysplasia (LGD) ...
Associated thoracic injury in patients with a clavicle fracture: a retrospective analysis of 1461 polytrauma patients

van Laarhoven, J. J E M; Hietbrink, F.; Ferree, S.; Gunning, A. C.; Houwert, R. M.; Verleisdonk, Egbert Jan M M; Leenen, L. P H (Springer International Publishing AG, 2019-02)

Purpose: During primary survey the main goal is to ascertain life-threatening injuries. A chest X-ray is recommended in all polytrauma patients as thoracic injury plays an important role in mortality. However, treatment-dictating ...
Planetary Health Diet Compared to Dutch Dietary Guidelines: Nutritional Content and Adequacy

Uriza-Pinzón, Julieth Pilar; Verstraete, Femke Fleur; Franco, Oscar H.; Artola Arita, Vicente; Nicolaou, Mary; Van der Schouw, Yvonne T. (Multidisciplinary Digital Publishing Institute (MDPI), 2024-07-11)

In 2019, the EAT-Lancet Commission proposed a Planetary Health Diet (PHD) to address challenges toward sustainable and healthy diets. However, its suitability within the Dutch context and a comparison with the Dutch Dietary ...
From pixels to pathophysiology - imaging immunity in cerebro- and cardiovascular disease

Meerwaldt, Anu E. (Utrecht University, 2024-09-27)

This thesis, consisting of six experimental chapters, shows the advantages of using high-field MRI and PET imaging together with targeted contrast agents and tracers for understanding pathophysiology and monitoring disease ...
Economic evaluations of exome sequencing for rare diseases within pediatric care

Olde Keizer, Richelle (Utrecht University, 2024-09-05)

In the last decade, the landscape of genetic testing has changed enormously. Genetic sequencing technologies are increasingly used for the diagnosis of rare genetic disorders. Exome sequencing (ES) is emerging as powerful ...
Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development

Rybiczka-Tešulov, Mateja; Garritsen, Oxana; Venø, Morten T.; Wieg, Laura; Dijk, Roland van; Rahimi, Karim; Gomes-Duarte, Andreia; Wit, Marina de; van de Haar, Lieke L.; Michels, Lars; van Kronenburg, Nicky C.H.; van der Meer, Christiaan; Kjems, Jørgen; Vangoor, Vamshidhar R.; Pasterkamp, R. Jeroen (Nature Publishing Group, 2024-08-08)

Midbrain dopamine (mDA) neurons play an essential role in cognitive and motor behaviours and are linked to different brain disorders. However, the molecular mechanisms underlying their development, and in particular the ...
Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer

Haughton, Peter D; Haakma, Wisse; Chalkiadakis, Theofilos; Breimer, Gerben E; Driehuis, Else; Clevers, Hans; Willems, Stefan; Prekovic, Stefan; Derksen, Patrick W B (Nature Publishing Group, 2024-08-02)

Clinical outcome for patients suffering from HPV-negative head and neck squamous cell carcinoma (HNSCC) remains poor. This is mostly due to highly invasive tumors that cause loco-regional relapses after initial therapeutic ...

Now showing items 5241-5260 of 40729