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UMC Repository: Recent submissions

  • Coronary Function Testing: The More, The Merrier? 
    Boerhout, Coen K.M.; van de Hoef, Tim P. (Elsevier, 2024-05-13)
  • Does Literature on Elbow Arthroscopy Put Complications Into Perspective? 
    Cross, Rachel E.; de Klerk, Huub H.; Hilgersom, Nick F.; Bhashyam, Abhiram R.; van den Bekerom, Michel P.J. (W.B. Saunders, 2024-05)
  • Lebrikizumab Provides Rapid Clinical Responses Across All Eczema Area and Severity Index Body Regions and Clinical Signs in Adolescents and Adults with Moderate-to-Severe Atopic Dermatitis 
    Simpson, Eric L.; de Bruin-Weller, Marjolein; Hong, H. Chih ho; Staumont-Sallé, Delphine; Blauvelt, Andrew; Eyerich, Kilian; Gooderham, Melinda; Shahriari, Mona; Mallbris, Lotus; Atwater, Amber Reck; Rueda, Maria Jose; Ding, Yuxin; Liu, Zhuqing; Agell, Helena; Silverberg, Jonathan I. (Springer-Verlag, 2024-05)
    Introduction: Atopic dermatitis (AD) affects multiple areas of the body, some of which may be more refractory to treatment. We evaluated improvements in the Eczema Area and Severity Index (EASI) by body region and clinical ...
  • Upadacitinib Rapidly Improves Patient-Reported Outcomes in Atopic Dermatitis: 16-Week Results from Phase 3 Clinical Trials (Measure Up 1 and 2) 
    Simpson, Eric L.; Prajapati, Vimal H.; Leshem, Yael A.; Chovatiya, Raj; de Bruin-Weller, Marjolein S.; Ständer, Sonja; Pink, Andrew E.; Calimlim, Brian M.; Lee, Wan Ju; Teixeira, Henrique; Ladizinski, Barry; Hu, Xiaofei; Yang, Yang; Liu, Yingyi; Liu, Meng; Grada, Ayman; Platt, Andrew M.; Silverberg, Jonathan I. (Springer-Verlag, 2024-05)
    Introduction: Atopic dermatitis (AD) is characterized by intense itch and other symptoms that negatively impact quality of life (QoL). This study evaluates the effect of upadacitinib (an oral selective Janus kinase inhibitor) ...
  • The Effects of FABP4 on Cardiovascular Disease in the Aging Population 
    van der Ark-Vonk, Ellen M.; Puijk, Mike V.; Pasterkamp, Gerard; van der Laan, Sander W. (Current Medicine Group, 2024-05)
    Purpose of Review: Fatty acid-binding protein 4 (FABP4) plays a role in lipid metabolism and cardiovascular health. In this paper, we cover FABP4 biology, its implications in atherosclerosis from observational studies, ...
  • Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus 
    van Ramshorst, Tess M.E.; van Hilst, Jony; Boggi, Ugo; Dokmak, Safi; Edwin, Bjørn; Keck, Tobias; Khatkov, Igor; Balduzzi, Alberto; Pulvirenti, Alessandra; Ahmad, Jawad; Saati, Hani Al; Alseidi, Adnan; Ausania, Fabio; Azagra, Juan S.; Balzano, Gianpaolo; Björnsson, Bergthor; Can, Fatih M.; Cillo, Umberto; D’Hondt, Mathieu; Efanov, Mikhail; Erkan, Mert; Alvarez, Francisco Espin; Esposito, Alessandro; Ferrari, Giovanni; Koerkamp, Bas Groot; Gumbs, Andrew A.; Hogg, Melissa E.; Ielpo, Benedetto; Ivanecz, Arpad; Jang, Jin Young; Kleive, Dyre; Kooby, David A.; Luyer, Misha D.P.; Marchegiani, Giovanni; Menon, Krishna; Molenaar, I. Quintus; Nagakawa, Yuichi; Nakamura, Masafumi; Palumbo, Diego; Piardi, Tullio; Ramia, Jose M.; Saint-Marc, Olivier; Salti, George I.; Strobel, Oliver; Vollmer, Charles M.; Wei, Alice C.; White, Steve; Yoon, Yoo Seok; Zerbi, Alessandro; Bassi, Claudio; Berrevoet, Frederik; Chan, Carlos; Coimbra, Felipe J.; Conlon, Kevin C.P.; Dervenis, Christos; Falconi, Massimo; Frigerio, Isabella; Fusai, Giuseppe K.; De Oliveira, Michelle L.; Pinna, Antonio D.; Primrose, John N.; Sauvanet, Alain; Serrablo, Alejandro; Smadi, Sameer; Alfieri, Sergio; Berti, Stefano; Butturini, Giovanni; Casadei, Riccardo; Coppola, Roberto; Benedetto, Fabrizio Di; Ettorre, Giuseppe M.; Giuliante, Felice; Jovine, Elio; Memeo, Riccardo; Pietrabissa, Andrea; Portolani, Nazario; Salvia, Roberto; Siriwardena, Ajith K.; Asbun, Horacio J.; Besselink, Marc G.; Hilal, Mohammad Abu (John Wiley & Sons Inc., 2024-04-01)
  • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 
    Kayode, Gbenga A.; GBD 2021 Diseases and Injuries Collaborators (Elsevier, 2024-05-18)
    Background: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury ...
  • Prevalence and phenotypes associated with ALPK3 null variants in a large French multicentric cohort: Confirming its involvement in hypertrophic cardiomyopathy 
    Ader, Flavie; Jedraszak, Guillaume; Janin, Alexandre; Billon, Clarisse; Buisson, Nathalie Roux; Bloch, Adrien; Bensalah, Meriem; De Sandre-Giovannoli, Anachiara; Goudal, Adeline; Marsili, Luisa; Cazeneuve, Cécile; Charron, Philippe; Millat, Gilles; Richard, Pascale (Wiley-Blackwell, 2024-06)
    Biallelic disease-causing variants in the ALPK3 gene were first identified in children presenting with a severe cardiomyopathy. More recently, it was shown that carriers of heterozygous ALPK3 null variants are at risk of ...
  • The Memory-CD8+-T-Cell Response to Conserved Influenza Virus Epitopes in Mice Is Not Influenced by Time Since Previous Infection 
    Lanfermeijer, Josien; van de Ven, Koen; Hendriks, Marion; van Dijken, Harry; Lenz, Stefanie; Vos, Martijn; Borghans, José A.M.; van Baarle, Debbie; de Jonge, Jørgen (Multidisciplinary Digital Publishing Institute, 2024-04)
    To protect older adults against influenza A virus (IAV) infection, innovative strategies are imperative to overcome the decrease in protective immune response with age. One approach involves the boosting of CD8+ T cells ...
  • Mesenchymal stromal/stem cells promote intestinal epithelium regeneration after chemotherapy-induced damage 
    Yetkin-Arik, B.; Jansen, S. A.; Varderidou-Minasian, S.; Westendorp, B.; Skarp, K. P.; Altelaar, M.; Lindemans, C. A.; Lorenowicz, M. J. (BioMed Central, 2024-04-29)
    BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for leukemia and a range of non-malignant disorders. The success of the therapy is hampered by occurrence of acute graft-versus-host ...
  • Mild and moderate COVID-19 during Alpha, Delta and Omicron pandemic waves in urban Maputo, Mozambique, December 2020-March 2022: A population-based surveillance study 
    Ingelbeen, Brecht; Cumbane, Victória; Mandlate, Ferão; Barbé, Barbara; Nhachungue, Sheila Mercedes; Cavele, Nilzio; Manhica, Cremildo; Cubai, Catildo; Nguenha, Neusa Maimuna Carlos; Lacroix, Audrey; Mariën, Joachim; de Weggheleire, Anja; van Kleef, Esther; Selhorst, Philippe; van der Sande, Marianne A.B.; Peeters, Martine; Widdowson, Marc Alain; Ismael, Nalia; Macicame, Ivalda (Public Library of Science, 2024-08-05)
    In sub-Saharan Africa, reported COVID-19 numbers have been lower than anticipated, even when considering populations’ younger age. The extent to which risk factors, established in industrialised countries, impact the risk ...
  • A context-based model to predict the intelligibility of sentences in non-stationary noises 
    van Schoonhoven, Jelmer; Rhebergen, Koenraad S.; Dreschler, Wouter A. (Acoustical Society of America, 2024-04-01)
    The context-based Extended Speech Transmission Index (cESTI) (van Schoonhoven et al., 2022, J. Acoust. Soc. Am. 151, 1404-1415) was successfully applied to predict the intelligibility of monosyllabic words with different ...
  • Benefits and risks of clofarabine in adult acute lymphoblastic leukemia investigated in depth by multi-state modeling 
    Hermans, Sjoerd J.F.; van Norden, Yvette; Versluis, Jurjen; Rijneveld, Anita W.; van der Holt, Bronno; de Weerdt, Okke; Biemond, Bart J.; van de Loosdrecht, Arjan A.; van der Wagen, Lotte E.; Bellido, Mar; van Gelder, Michel; van der Velden, Walter J.F.M.; Selleslag, Dominik; van Lammeren-Venema, Daniëlle; van der Velden, Vincent H.J.; de Wreede, Liesbeth C.; Postmus, Douwe; Pignatti, Francesco; Cornelissen, Jan J. (John Wiley & Sons Inc., 2024-05)
    Background: We recently reported results of the prospective, open-label HOVON-100 trial in 334 adult patients with acute lymphoblastic leukemia (ALL) randomized to first-line treatment with or without clofarabine (CLO). ...
  • Nonoperative treatment of multiple rib fractures, the results to beat: International multicenter prospective cohort study among 845 patients 
    Peuker, Felix; Hoepelman, Ruben J.; Beeres, Frank J.P.; Balogh, Zsolt J.; Beks, Reinier B.; Sweet, Arthur A.R.; Ijpma, Frank F.A.; Lansink, Koen W.W.; Van Wageningen, Bas; Tromp, Tjarda N.; Minervini, Fabrizio; Van Veelen, Nicole M.; Hoogendoorn, Jochem M.; De Jong, Mirjam B.; Van Baal, Mark C.P.M.; Leenen, Luke P.H.; Groenwold, Rolf H.H.; Houwert, R. Marijn (Lippincott Williams & Wilkins, 2024-05-01)
    BACKGROUND Optimal treatment (i.e., nonoperative or operative) for patients with multiple rib fractures remains debated. Studies that compare treatments are rationalized by the alleged poor outcomes of nonoperative treatment. ...
  • Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population 
    Ahmed, Yunus; Van Bakel, Pieter A.J.; Hou, Hechuan; Sukul, Devraj; Likosky, Donald S.; Van Herwaarden, Joost A.; Watkins, Daphne C.; Ailawadi, Gorav; Patel, Himanshu J.; Thompson, Michael P.; Structural Heart and Aortic Diseases Outcomes Research Workgroup Investigators (Public Library of Science, 2023-04)
    Importance Aortic stenosis (AS) is one of the most common heart valve conditions and its incidence and prevalence increases with age. With the introduction of transcatheter aortic valve replacement (TAVR), racial and ethnic ...
  • Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer 
    Thurlings, I.; Martínez-López, L. M.; Westendorp, B.; Zijp, M.; Kuiper, R.; Tooten, P.; Kent, L. N.; Leone, G.; Vos, H. J.; Burgering, B.; de Bruin, A. (Nature Publishing Group, 2017)
    E2F transcription factors are important regulators of the cell cycle, and unrestrained activation of E2F-dependent transcription is considered to be an important driver of tumor formation and progression. Although highly ...
  • Profiling of circulating microRNAs in patients with Barrett’s esophagus and esophageal adenocarcinoma 
    Bus, Pauline; Kestens, Christine; Ten Kate, Fiebo Jan Willem; Peters, Wilbert; Drenth, Joost Paulus Hubertus; Roodhart, Jeanine Merel Leonoor; Siersema, Peter Derk; van Baal, Jantine Wilhelmina Paula Maria (Springer, 2016)
    Background: Circulating microRNAs (miRNAs) have been suggested as novel markers for various diseases. The goal of this pilot study was to identify circulating miRNAs differentially expressed comparing Barrett’s esophagus ...
  • Update of EULAR recommendations for the treatment of systemic sclerosis 
    Kowal-Bielecka, Otylia; Fransen, Jaap; Avouac, Jerome; Becker, Mike; Kulak, Agnieszka; Allanore, Yannick; Distler, Oliver; Clements, Philip; Cutolo, Maurizio; Czirjak, Laszlo; Damjanov, Nemanja; del Galdo, Francesco; Denton, Christopher P.; Distler, Jörg H W; Foeldvari, Ivan; Figelstone, Kim; Frerix, Marc; Furst, Daniel E.; Guiducci, Serena; Hunzelmann, Nicolas; Khanna, Dinesh; Matucci-Cerinic, Marco; Herrick, Ariane L.; van den Hoogen, Frank; van Laar, Jacob M.; Riemekasten, Gabriela; Silver, Richard; Smith, Vanessa; Sulli, Alberto; Tarner, Ingo; Tyndall, Alan; Welling, Joep; Wigley, Frederic; Valentini, Gabriele; Walker, Ulrich A.; Zulian, Francesco; Müller-Ladner, Ulf; Daikeler, Thomas; Lanciano, Elisabetta; Becvár, Radim; Tomcik, Michal; Gindzienska-Sieskiewicz, Ewa; Iudici, Michele; Rednic, Simona; Vlachoyiannopoulos, Panayiotis G.; Caporali, Roberto; Carreira, Patricia E.; Novak, Srdan; Minier, Tünde; Kucharz, Eugene J.; Gabrielli, Armando; Moroncini, Gianluca; Airo, Paolo; Hesselstrand, Roger; Martinovic, Duska; Radic, Mislav; Marasovic-Krstulovic, Daniela; Braun-Moscovici, Yolanda; Monaco, Andrea Lo; Morovic-Vergles, Jadranka; Culo, Melanie I.; Henes, Jörg; Santamaria, Vera Ortiz; Heitmann, Stefan; Krasowska, Dorota; Michalska-Jakubus, Malgorzata; Seidel, Matthias F.; Klinik, Medizinische; Hasler, Paul; Da Silva, José A Pereira; Salvador, Maria J.; Stamenkovic, Bojana; Stankovic, Aleksandra; Tikly, Mohammed; Ananieva, Lidia P.; Beretta, Lorenzo; Szucs, Gabriella; Szamosi, Szilvia; de la Puente Bujidos, Carlos; Midtvedt, Øyvind; Hoffmann-Vold, Anna Maria; Launay, David; Hachulla, Eric; Riccieri, Valeria; Ionescu, Ruxandra; Opris, Daniela; Mihai, Carina; Herrgott, Ilka; Beyer, Christian; Ingegnoli, Francesca; von Mühlen, Carlos Alberto; Alegre-Sancho, Juan José; Beltran-Catalan, Emma; Aringer, Martin; Fantana, Julia; Leuchten, Nicolai; Tausche, Anne Kathrin; Langhe, Ellen De; Vanthuyne, Marie; Anic, Branimir; Barešic, Marko; Mayer, Miroslav; üprus, Maria; Otsa, Kati; Yavuz, Sule; Granel, Brigitte; Jimenez, Sergio A.; Popa, Serghei; Agachi, Svetlana; Zenone, Thierry; Stebbings, Simon; Dockerty, Joanne; Vacca, Alessandra; Schollum, Joanna; Veale, Douglas J.; Toloza, Sergio; Xu, Dong; Olas, Jacek; Rosato, Edoardo; Foti, Rosario; Adler, Sabine; Dan, Diana; Wiesik-Szewczyk, Ewa; Olesinska, Marzena; Kayser, Cristiane; Fathi, Nihal; de la Peña Lefebvre, Paloma García; Imbert, Bernard (Elsevier, 2017-08)
    The aim was to update the 2009 European League against Rheumatism (EULAR) recommendations for the treatment of systemic sclerosis (SSc), with attention to new therapeutic questions. Update of the previous treatment ...
  • Graph analysis of the anatomical network organization of the hippocampal formation and parahippocampal region in the rat 
    Binicewicz, F. Z M; Van Strien, N. M.; Wadman, W. J.; Van Den Heuvel, M. P.; van den Heuvel, MP; Cappaert, N. L M (Springer-Verlag, 2016)
    Graph theory was used to analyze the anatomical network of the rat hippocampal formation and the parahippocampal region (van Strien et al., Nat Rev Neurosci 10(4):272–282, 2009). For this analysis, the full network was ...
  • Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound 
    Hazenberg, Constantijn E.V.B.; Wulms, Suzan C.A.; Klaassen, Jurre; van Herwaarden, Joost A. (MYJoVE Corporation, 2023-04)
    Vascular surgeons and interventional radiologists face chronic exposure to low-dose radiation during endovascular procedures, which may impact their health in the long term due to their stochastic effects. The presented ...