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Criteria for second generation comparator tests in validation of novel HPV DNA tests for use in cervical cancer screening

Arbyn, Marc; Cuschieri, Kate; Bonde, Jesper; Schuurman, Rob; Cocuzza, Clementina; Broeck, Davy Vanden; Zhao, Fang Hui; Rezhake, Remila; Gultekin, Murat; de Sanjosé, Silvia; Canfell, Karen; Hawkes, David; Saville, Marion; Hillemanns, Peter; Dillner, Joakim; Berkhof, Johannes; Prétet, Jean Luc; Gheit, Tarik; Clifford, Gary; Basu, Partha; Almonte, Maribel; Wentzensen, Nicolas; Poljak, Mario (John Wiley & Sons Inc., 2024-09)

While HC2 and GP5+/6+ PCR-EIA were pivotal in test validation of new HPV assays, they represent the first generation of comparator tests based upon technologies that are not in widespread use anymore. In the current ...
The Development of a European Multidisciplinary Cleft Lip and Palate Registry by the European Reference Network CRANIO: Experiences, Barriers, And Facilitators

van der Goes, Philip A.J.; Ombashi, Saranda; van Roey, Victor; Hakelius, Malin; Mathijssen, Irene M.J.; Mink van der Molen, Aebele B.; Versnel, Sarah L. (Lippincott Williams & Wilkins, 2024-09-01)

The European Reference Network for Rare Craniofacial Aanomalies and Ear-Nose-Throat disorders aims to improve care for patients with such afflictions, including cleft lip and palate (CL/P) across Europe. Cleft treatment ...
An observational cohort of patients with colorectal peritoneal metastases or pseudomyxoma peritonei treated with CRS-HIPEC: Development and first results of the Dutch CRS-HIPEC quality registry

van Erning, Felice N.; van den Heuvel, Teun B.M.; Sijtsma, Femke P.C.; Boerma, Djamila; Brandt-Kerkhof, Alexandra R.M.; Bremers, André J.; van Duyn, Eino B.; van Grevenstein, Helma M.U.; Hemmer, Patrick H.J.; Kok, Niels F.M.; Madsen, Eva; de Reuver, Philip R.; Wiezer, René J.; Witkamp, Arjan J.; Nienhuijs, Simon W.; Poelmann, Floris B.; Tuynman, Jurriaan B.; Been, Lucas B.; Rovers, Koen P.; de Hingh, Ignace H.J.T. (W.B. Saunders Ltd, 2024-12)

Introduction: To improve care for patients with colorectal peritoneal metastases (CRC-PM) or pseudomyxoma peritonei (PMP), the Dutch CRS-HIPEC quality registry was initiated in 2019. The aims are to describe the development ...
Expanded PAH analysis of household air pollution in a rural region of China with high lung cancer incidence

Zhang, Yongliang; Meliefste, Kees; Hu, Wei; Portengen, Lützen; Rothman, Nathaniel; Reiss, Boris; Li, Jihua; Xu, Jun; Ning, Baofu; Liu, Dingyu; Cassee, Flemming R.; Wong, Jason Y.Y.; Vermeulen, Roel; Lan, Qing; Downward, George S. (Elsevier, 2024-11-15)

The domestic combustion of locally sourced smoky (bituminous) coal in Xuanwei and Fuyuan counties, China, is responsible for some of the highest lung cancer rates in the world. Recent research has pointed to methylated ...
Centralization and Quality Control in Esophageal Cancer Surgery: a Way Forward in Europe

Visser, Maurits R; van Berge Henegouwen, Mark I; van Hillegersberg, Richard (Wiley-Blackwell, 2024-09)

Background and Hypothesis Recent findings suggest the incidence of first-episode psychotic disorders (FEP) varies according to setting-level deprivation and cannabis use, but these factors have not been investigated together. ...
Predictors of postoperative lumpectomy size in breast-conserving surgery in breast cancer patients: a retrospective cohort study

Makineli, Seher; Strijbis, Rogier; Tsehaie, Jonathan; Schellekens, Pascal P A; Moman, Maaike; Veenendaal, Liesbeth; Ferdinandus, P; Witkamp, Arjen J; Richir, Milan; Maarse, Wies (Lippincott Williams & Wilkins, 2024-09)

BACKGROUND: Oncoplastic reconstructive surgery as an extension of breast-conserving surgery leads to better aesthetic results, an increase in tumor-free margins, and a reduction of re-excision rates. However, oncologic ...
Rare disease gene association discovery from burden analysis of the 100,000 Genomes Project data

Cipriani, Valentina; Vestito, Letizia; Magavern, Emma F; Jacobsen, Julius Ob; Arno, Gavin; Behr, Elijah R; Benson, Katherine A; Bertoli, Marta; Bockenhauer, Detlef; Bowl, Michael R; Burley, Kate; Chan, Li F; Chinnery, Patrick; Conlon, Peter; Costa, Marcos; Davidson, Alice E; Dawson, Sally J; Elhassan, Elhussein; Flanagan, Sarah E; Futema, Marta; Gale, Daniel P; García-Ruiz, Sonia; Corcia, Cecilia Gonzalez; Griffin, Helen R; Hambleton, Sophie; Hicks, Amy R; Houlden, Henry; Houlston, Richard S; Howles, Sarah A; Kleta, Robert; Lekkerkerker, Iris; Lin, Siying; Liskova, Petra; Mitchison, Hannah; Morsy, Heba; Mumford, Andrew D; Newman, William G; Neatu, Ruxandra; O'Toole, Edel A; Ong, Albert Cm; Pagnamenta, Alistair T; Rahman, Shamima; Rajan, Neil; Robinson, Peter N; Ryten, Mina; Sadeghi-Alavijeh, Omid; Sayer, John A; Shovlin, Claire L; Taylor, Jenny C; Teltsh, Omri; Tomlinson, Ian; Tucci, Arianna; Turnbull, Clare; van Eerde, Albertien M; Ware, James S; Watts, Laura M; Webster, Andrew R; Westbury, Sarah K; Zheng, Sean L; Caulfield, Mark; Smedley, Damian (medRxivCold Spring Harbor Laboratory Press, 2023-12-21)

To discover rare disease-gene associations, we developed a gene burden analytical framework and applied it to rare, protein-coding variants from whole genome sequencing of 35,008 cases with rare diseases and their family ...
Indocyanine green fluorescence perfusion testing in robot-assisted hepatic arterial infusion pump placement

van Dorst, Roderick W.J.J.; Ten Haaft, Britte H.E.A.; Franssen, Stijn; Borel Rinkes, Inne H.M.; Groot Koerkamp, Bas; Swijnenburg, Rutger Jan; Hagendoorn, Jeroen (Springer New York, 2024-09)

Background: Hepatic arterial infusion pump (HAIP) treatment is a technique used to treat liver localized malignancy with intra-arterial chemotherapy. Methylene blue is generally administered to verify hepatic perfusion and ...
The NOS1AP gene rs10494366 common genetic variant does not modify the risk of sudden cardiac death in users of digoxin

Soroush, Negin; Aarnoudse, Albert-Jan; Kavousi, Maryam; Kors, Jan A; Ikram, M Arfan; Stricker, Bruno H; Ahmadizar, Fariba (Wiley-Blackwell, 2024-09)

Aims: Common genetic variations in the nitric oxide synthase-1 adaptor protein (NOS1AP) gene are associated with QT-interval prolongation. In a previous study, we observed an association between the rs10494366 variant of ...
Centralized intestinal organoid generation is a feasible and safe approach for personalized medicine as demonstrated in the HIT-CF Europe Organoid Study

HIT-CF organoid study group (Elsevier, 2024-07)

BACKGROUND: Patient-derived intestinal organoids (PDIOs) show great potential as in vitro drug testing platform for personalised medicine in Cystic Fibrosis and oncology. PDIOs can be generated by culturing adult stem cells ...
The plasma proteome is linked with left ventricular and left atrial function parameters in patients with chronic heart failure

Abou Kamar, S.; Andrzejczyk, K.; Petersen, T. B.; Chin, J. F.; Aga, Y. S.; De Bakker, M.; Akkerhuis, K. M.; Geleijnse, M.; Brugts, J. J.; Sorop, O.; De Boer, R. A.; Rizopoulos, D.; Asselbergs, F. W.; Boersma, E.; Den Ruijter, H.; Van Dalen, B. M.; Kardys, I. (Oxford University Press, 2024-09-01)

Aims: Examining the systemic biological processes in the heterogeneous syndrome of heart failure with reduced ejection fraction (HFrEF), as reflected by circulating proteins, in relation to echocardiographic characteristics, ...
Cyclical Etidronate Reduces the Progression of Arterial Calcifications in Patients with Pseudoxanthoma Elasticum: A 6-Year Prospective Observational Study

Harmsen, Iris M.; van den Beukel, Tim; Kok, Madeleine; Visseren, Frank L.J.; de Jong, Pim A.; Papapoulos, Socrates E.; Spiering, Wilko (Multidisciplinary Digital Publishing Institute (MDPI), 2024-08)

Background: Pseudoxanthoma elasticum (PXE), a rare genetic disorder presenting with slowly progressing calcification of various tissues, including the arteries, is caused by mutations in the ABCC6 gene that lead to the ...
Integrating telemedicine in routine heart failure management: Experiences of healthcare professionals – A qualitative study

van Eijk, Jorna; Trappenburg, Jaap; Asselbergs, Folkert W.; Jaarsma, Tiny (SAGE Publications Sage UK: London, England, 2024-08-28)

Objective: To describe the experiences of healthcare professionals with integrating telemedicine in routine heart failure (HF) care. Methods: Semi-structured interviews were conducted with healthcare professionals (n = 19) ...
Results from a phase I study of 4-l-[131I]iodo-phenylalanine ([131I]IPA) with external radiation therapy in patients with recurrent glioblastoma (IPAX-1)

Pichler, Josef; Traub-Weidinger, Tatjana; Spiegl, Kurt; Imamovic, Larisa; Braat, Arthur J.A.T.; Snijders, Tom J.; Verhoeff, Joost J.C.; Flamen, Patrick; Tauchmanova, Libuse; Hayward, Colin; Kluge, Andreas (Oxford University Press, 2024)

Background. Glioblastoma (GBM), the most common malignant brain tumor, is associated with devastating outcomes. IPAX-1 was a multicenter, open-label, single-arm phase I study to evaluate carrier-added 4-L-[131I]iodo-phenylalanine ...
Surgical versus conservative treatment for odontoid fractures in older people: an international prospective comparative study

Huybregts, Jeroen G.J.; Polak, Samuel B.; Jacobs, Wilco C.; Arts, Mark P.; Meyer, Bernhard; Wostrack, Maria; Butenschön, Vicki M.; Osti, Michael; Öner, F. Cumhur; Slooff, Willem Bart M.; Feller, Ricardo E.; Bouma, Gert Joan; Harhangi, Biswadjiet S.; Depreitere, Bart; Nygaard, Øystein P.; Weber, Clemens; Müller, Kay; Timothy, Jake; Pellisé, Ferran; Rasmussen, Mikkel M.; van Zwet, Erik W.; Steyerberg, Ewout W.; Peul, Wilco C.; Vleggeert-Lankamp, Carmen L.A. (Oxford University Press, 2024-08-01)

Background: The optimal treatment for odontoid fractures in older people remains debated. Odontoid fractures are increasingly relevant to clinical practice due to ageing of the population. Methods: An international prospective ...
Optimal treatment for women with acute hypertension in pregnancy; a randomized trial comparing intravenous labetalol versus nicardipine

bij de Weg, Jeske M.; de Boer, Marjon A.; Gravesteijn, Benjamin Y.; Hermes, Wietske; Ganzevoort, Wessel; van Bel, Frank; Willem Mol, Ben; de Groot, Christianne J.M. (Elsevier, 2024-12)

Objectives: Blood pressure control in severe hypertension of pregnancy is crucial for mother and neonate. In absence of evidence, guidelines recommend either intravenous labetalol or nicardipine. We compared the effectiveness ...
The Diagnostic Value of ECG Characteristics for Vasospastic and Microvascular Angina: A Systematic Review

Schipaanboord, Diantha J M; Woudstra, Janneke; Appelman, Yolande; Rittersma, Saskia Z H; van de Hoef, Tim P; van Es, René; Coronel, Ruben; Damman, Peter; van der Harst, Pim; Onland-Moret, N. Charlotte; den Ruijter, Hester M (Wiley-Blackwell, 2024-09)

Background: Coronary vascular dysfunction comprises VSA and/or MVA and is more common in women than in men with angina without obstructive coronary artery disease (ANOCA). Invasive coronary function testing is considered ...
Prevalence of placental bed spiral artery pathology in preeclampsia and fetal growth restriction: A prospective cohort study

Brouwers, Laura; de Gier, Steffie; Vogelvang, Tatjana E.; Veerbeek, Jan H.W.; Franx, Arie; van Rijn, Bas B.; Nikkels, Peter G.J. (W.B. Saunders Ltd, 2024-10)

Background: Preeclampsia and fetal growth restriction (PE/FGR) are pregnancy complications known to be associated with poor utero-placental function due to abnormal “physiological” remodeling of spiral arteries and unfavorable ...
Secondary Prevention of Coronary Heart Disease: Global Perspectives

Marza Florensa, Anna (Utrecht University, 2024-10-03)

The burden of coronary heart disease (CHD) is increasing, and most of it is related to cardiovascular risk factors. Clinical guidelines recommend that CHD patients change health behaviors and use medication to modify and ...
Performance evaluation of the quantitative assay Adenovirus ELITe MGB® Kit on EDTA-plasma, using the ELITe BeGenius® system

Fries, Edwin; Kalmeijer, Tessa; Spaans, Lara; Rakké, Martin; Schuurman, Rob; De Groot-Mijnes, Jolanda D.F. (Elsevier, 2024-10)

Background: Adenovirus infections constitute an important cause of morbidity and mortality after hematopoietic stem cell transplantation. Detection and monitoring of adenovirus in EDTA-plasma by real-time quantitative PCR ...

Now showing items 4681-4700 of 40729