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SARS-CoV-2 antibody response dynamics and heterogeneous diagnostic performance of four serological tests and a neutralization test in symptomatic healthcare workers with non-severe COVID-19

Ong, David S Y; Keuren, Frans; van der Vliet, Marijke; Boxma-de Klerk, Bianca M; Koeleman, Johannes G M (Elsevier, 2021-08)

BACKGROUND: Most COVID-19 patients experience non-severe illness. The presence of SARS-CoV-2 antibodies suggest possible protection against re-infections in prior SARS-CoV-2 infected individuals. OBJECTIVES: The aims of ...
Trends in SARS-CoV-2 seroprevalence amongst urban paediatric patients compared with a nationwide cohort in the Netherlands

Rotee, I L M; Ong, D S Y; Koeleman, J G M; Vos, E R A; Tramper-Stranders, G A (Elsevier, 2021-12)

Objectives: The extent of SARS-CoV-2 infection amongst children and their role in transmission remains unclear. Therefore, we aimed to estimate the SARS-CoV-2 antibody seroprevalence amongst children who presented to our ...
Economic and cost-effectiveness analysis of the Community-Level Interventions for Pre-eclampsia (CLIP) trials in India, Pakistan and Mozambique

Bone, Jeffrey N.; Khowaja, Asif R.; Vidler, Marianne; Payne, Beth A.; Bellad, Mrutyunjaya B.; Goudar, Shivaprasad S.; Mallapur, Ashalata A.; Munguambe, Khatia; Qureshi, Rahat N.; Sacoor, Charfudin; Sevene, Esperanca; Frederix, Geert W.J.; Bhutta, Zulfiqar A.; Mitton, Craig; Magee, Laura A.; Von Dadelszen, Peter (BMJ Publishing Group, 2021-05-24)

Background The Community-Level Interventions for Pre-eclampsia (CLIP) trials (NCT01911494) in India, Pakistan and Mozambique (February 2014-2017) involved community engagement and task sharing with community health workers ...
Teleconsulten op de polikliniek geriatrie in Nederland – ervaringen van zorgverleners

Flamand, Eva; Emmelot-Vonk, M H; van der Linden, Carolien M J; van Munster, Barbara C (Nederlands Instituut voor Gerontologie (NIG), 2021-12-07)

The use of telemedicine (telephone and video consultations) has increased over the past decades and has grown substantially during the COVID-19 pandemic. Multimorbidity, visual - and hearing impairment, cognitive impairment ...
The effects of percutaneous branch pulmonary artery interventions in biventricular congenital heart disease: study protocol for a randomized controlled Dutch multicenter interventional trial

Joosen, R S; Voskuil, M; Krasemann, T B; Blom, N A; Krings, G J; Breur, J M P J; Outreach consortium (BioMed Central, 2024-09-03)

BACKGROUND: Branch pulmonary artery (PA) stenosis is one of the most common indications for percutaneous interventions in patients with transposition of the great arteries (TGA), tetralogy of Fallot (ToF), and truncus ...
Care decision conversations: Improving communication about treatment wishes and limitations: how to prepare patients and physicians

Pater - Briedé, Saskia (Utrecht University, 2024-09-30)

Care Decision Conversations: Improving communication about treatment wishes and limitations: how to prepare patients and physicians In our thesis, we explore how to enhance conversations about care decisions between doctors ...
Maturation of the spine and its consequences for conservative treatment of adolescent idiopathic scoliosis

Costa, Lorenzo (Utrecht University, 2024-10-14)

Idiopathic scoliosis (AIS) is a complex spinal deformity of unknown cause. It often involves lateral curvature, axial rotation and thoracic kyphosis, leading to significant physical, psychological and social challenges. ...
GEOGRAPHY OF A RARE DISEASE: A SHIFTING LANDSCAPE TOWARDS DIFFUSE MIDLINE GLIOMA (DMG)

Baugh, Joshua Norman (Utrecht University, 2024-10-01)

This thesis aims to describe the clinical and translational landscape of DIPG, and the research challenges addressed in my PhD project. I aim to 1) describe the development and establishment of a centralized data collection ...
Author Correction: Clinical implementation of artificial-intelligence-assisted detection of breast cancer metastases in sentinel lymph nodes: the CONFIDENT-B single-center, non-randomized clinical trial (Nature Cancer, (2024), 5, 8, (1195-1205), 10.1038/s43018-024-00788-z)

van Dooijeweert, C; Flach, R N; Ter Hoeve, N D; Vreuls, C P H; Goldschmeding, R; Freund, J E; Pham, P; Nguyen, T Q; van der Wall, E; Frederix, G W J; Stathonikos, N; van Diest, P J (Nature Research, 2024-08)

In the version of the article initially published, the arrows were missing in Fig. 1 between both instances of “Pathologist” and “No tumor”. The figure has now been amended in the HTML and PDF versions of the article.
Marizomib for patients with newly diagnosed glioblastoma: a randomized phase 3 trial

EORTC Brain Tumor Group and the Canadian Cancer Trials Group (Oxford University Press, 2024-09-05)

BACKGROUND: Standard treatment for patients with newly diagnosed glioblastoma includes surgery, radiotherapy (RT), and temozolomide (TMZ) chemotherapy (TMZ/RT→TMZ). The proteasome has long been considered a promising ...
Toward Transplantation of Liver Organoids: From Biology and Ethics to Cost-effective Therapy

Ten Dam, Marjolein J.M.; Frederix, Geert W.J.; Ten Ham, Renske M.T.; Van Der Laan, Luc J.W.; Schneeberger, Kerstin (Lippincott Williams & Wilkins, 2023-08-01)

Liver disease is a common cause of morbidity and mortality, and many patients would benefit from liver transplantation. However, because of a shortage of suitable donor livers, even of those patients who are placed on the ...
Traffic-related air pollution, road traffic noise, and Parkinson's disease: Evaluations in two Dutch cohort studies

Lomme, Jara; Reedijk, Marije; Peters, Susan; Downward, George S; Stefanopoulou, Magdalini; Vermeulen, Roel; Huss, Anke (Wolters Kluwer Health, 2023-12)

Background: Environmental factors such as air pollution have been associated with Parkinson's disease (PD), but findings have been inconsistent. We investigated the association between exposure to several air pollutants, ...
Common core variables for childhood cancer data integration

Di Carlo, Daniela; Ladenstein, Ruth; Graf, Norbert; Merks, Johannes Hans; Hernández-Peñaloza, Gustavo; Kearns, Pamela; Bisogno, Gianni (Elsevier, 2024-12)

Introduction: Data-driven research has improved paediatric cancer outcomes for children. However, challenges in sharing data between institutions prevent the use of artificial intelligence (AI) to address substantial unmet ...
Age-specific sex differences in intravascular ultrasound based coronary atherosclerotic plaque characteristics

Ligthart, Jurgen; de Bakker, Marie; Witberg, Karen; ten Cate, Folkert; den Ruijter, Hester; Daemen, Joost; Van Mieghem, Nicolas M.; Boersma, Eric (Elsevier, 2024-10)

Insights in age- and sex-specific coronary atherosclerotic plaque characteristics may contribute to a better understanding of coronary artery disease and, ultimately, to its prevention and treatment. In 307 women and 406 ...
Plasma Biomarkers of Brain Injury and Their Association With Brain MRI and Cognition in Type 1 Diabetes

Karger, Amy B.; Nasrallah, Ilya M.; Braffett, Barbara H.; Luchsinger, José A.; Ryan, Christopher M.; Bebu, Ionut; Arends, Valerie; Habes, Mohamad; Gubitosi-Klug, Rose A.; Chaytor, Naomi; Biessels, Geert J.; Jacobson, Alan M.; for the DCCT/EDIC Research Group (American Diabetes Association Inc., 2024-09)

OBJECTIVE To evaluate associations between plasma biomarkers of brain injury and MRI and cognitive measures in participants with type 1 diabetes (T1D) from the Diabetes Control and Complications Trial/Epidemiology of ...
The Practical Application of the Individual Care Plan for Pediatric Palliative Care: A Mixed-Method Study

Project Team ICP (MDPI AG, 2024-08)

Background/Objective: The Individual Care Plan (ICP) for pediatric palliative care was developed to provide person-centered care for the individual child and family. Currently, a lack of clarity remains regarding the use ...
The prognostic value of visual and automatic coronary calcium scoring from low-dose computed tomography-[15O]-water positron emission tomography

Dobrolinska, M. M.; Jukema, R. A.; Van Velzen, S. G.M.; Van Diemen, P. A.; Greuter, M. J.W.; Prakken, N. H.J.; Van Der Werf, N. R.; Raijmakers, P. G.; Slart, R. H.J.A.; Knaapen, P.; Isgum, I.; Danad, I. (Oxford University Press, 2024-09-01)

Aims: The study aimed, firstly, to validate automatically and visually scored coronary artery calcium (CAC) on low-dose computed tomography (CT) (LDCT) scans with a dedicated calcium scoring CT (CSCT) scan and, secondly, ...
Efficacy of anti PD-1 therapy in children and adolescent melanoma patients (MELCAYA study)

Mandalà, Mario; Ferrari, Andrea; Brecht, Ines B.; Suijkerbuijk, Karijn PM; Maschke, Linda; Giannarelli, Diana; Indini, Alice; Ubaldi, Martina; Pecci, Giulia; Atkinson, Victoria; Helgadottir, Hildur; Chiaravalli, Stefano; Benannoune, Naima; Robert, Caroline; Teterycz, Pawel; Rutkowski, Piotr; Puig, Susana; Madonna, Gabriele; Kebudi, Rejin; Grynberg, Shirly; Arantes, Lidia MRB; Bien, Ewa; Krawczyk, Malgorzata; Pasquale, Maria Debora De; Dierselhuis, Miranda P.; Massi, Daniela; Long, Georgina V.; Ascierto, Paolo Antonio; Eggermont, Alexander M.M. (Elsevier Limited, 2024-11)

Background: Data on the efficacy and safety of anti PD-1 antibodies in children and adolescents (CA) with melanoma are lacking. The aim of this study was to determine outcomes of CA melanoma patients receiving anti PD-1 ...
Are Current Survival Prediction Tools Useful When Treating Subsequent Skeletal-related Events From Bone Metastases?

Pan, Yu Ting; Lin, Yen Po; Yen, Hung Kuan; Yen, Hung Ho; Huang, Chi Ching; Hsieh, Hsiang Chieh; Janssen, Stein; Hu, Ming Hsiao; Lin, Wei Hsin; Groot, Olivier Q. (Springer New York, 2024-09-01)

Background Bone metastasis in advanced cancer is challenging because of pain, functional issues, and reduced life expectancy. Treatment planning is complex, with consideration of factors such as location, symptoms, and ...
The impact of cut-off values on the prevalence of short cervical length in pregnancy

Breuking, Sofie H.; van Dijk, Charlotte E.; van Gils, Annabelle L.; van Zijl, Maud D.; Kazemier, Brenda M.; Pajkrt, E.; for the Quadruple P research group (Elsevier Ireland Ltd, 2024-11)

Background: A prior study suggested that implementing a cut-off value of ≤30 mm for a short cervical length (CL) could potentially introduce selection bias and alter the distribution of CL measurements. As such, the objective ...

Now showing items 4661-4680 of 40729