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UMC Repository: Recent submissions

  • Transdiagnostic dimensions of psychopathology at first episode psychosis: findings from the multinational EU-GEI study 
    Quattrone, Diego; Di Forti, Marta; Gayer-Anderson, Charlotte; Ferraro, Laura; Jongsma, Hannah E.; Tripoli, Giada; La Cascia, Caterina; La Barbera, Daniele; Tarricone, Ilaria; Berardi, Domenico; Szoke, Andrei; Arango, Celso; Lasalvia, Antonio; Tortelli, Andrea; Llorca, Pierre-Michel; de Haan, Lieuwe; Velthorst, Eva; Bobes, Julio; Bernardo, Miguel; Sanjuan, Julio; Luis Santos, Jose; Arrojo, Manuel; Del-Ben, Cristina Marta; Menezes, Paulo Rossi; Selten, Jean-Paul; Jones, Peter B.; Kirkbride, James B.; Richards, Alexander L.; O'Donovan, Michael C.; Sham, Pak C.; Vassos, Evangelos; Rutten, Bart P. F.; van Os, Jim; Morgan, Craig; Lewis, Cathryn M.; Murray, Robin M.; Reininghaus, Ulrich; Hubbard, Kathryn; Beards, Stephanie; Stilo, Simona A.; Parellada, Mara; Cuadrado, Pedro; Rodriguez Solano, Jose Juan; Carracedo, Angel; Garcia Bernardo, Enrique; Roldan, Laura; Lopez, Gonzalo; Cabrera, Bibiana; Lorente-Rovira, Esther; Garcia-Portilla, Paz; Costas, Javier; Jimenez-Lopez, Estela; Matteis, Mario; Rapado, Marta; Gonzalez, Emiliano; Martinez, Covadonga; Sanchez, Emilio; Olmeda, Ma Soledad; Franke, Nathalie; Termorshuizen, Fabian; van Dam, Daniella; van der Ven, Elsje; Messchaart, Elles; Leboyer, Marion; Schurhoff, Franck; Jamain, Stephane; Baudin, Gregoire; Ferchiou, Aziz; Pignon, Baptiste; Richard, Jean-Romain; Charpeaud, Thomas; Tronche, Anne-Marie; Frijda, Flora; Marrazzo, Giovanna; Sideli, Lucia; Sartorio, Crocettarachele; Seminerio, Fabio; Loureiro, Camila Marcelino; Shuhama, Rosana; Ruggeri, Mirella; Tosato, Sarah; Bonetto, Chiara; Cristofalo, Doriana (Cambridge University Press, 2019-06)
    BACKGROUND: The value of the nosological distinction between non-affective and affective psychosis has frequently been challenged. We aimed to investigate the transdiagnostic dimensional structure and associated characteristics ...
  • Surgical Treatment of Acute Thoracic Stent Graft Occlusion 
    Liesdek, Omayra C.D.; Jacob, Kirolos A.; Vink, Aryan; Vermeulen, Marijn A.; Hazenberg, Constantijn E.V.B.; Suyker, Willem J.L. (Elsevier, 2019-02-01)
    A 24-year-old man presented with acute onset paraplegia related to complete occlusion of a thoracic stent graft placed 2 years prior for repair of traumatic type B aortic dissection. Following emergency surgery comprising ...
  • Acute wheeze in the pediatric population: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data 
    Katz, Mark A.; Marangu, Diana; Attia, Engi F.; Bauwens, Jorgen; Bont, Louis J.; Bulatovic, Annamaria; Crane, Julian; Doroshenko, Alexander; Ebruke, Bernard E.; Edwards, Kathryn M.; Fortuna, Librada; Jagelaviciene, Agne; Joshi, Jyoti; Kemp, James; Kovacs, Stephanie; Lambach, Philipp; Lewis, Kristen D.C.; Ortiz, Justin R.; Simões, Eric A F; Turner, Paul; Tagbo, Beckie N.; Vaishnavi, Vikas; Bonhoeffer, Jan (Elsevier, 2019-01-07)
  • Return to work after mild-to-moderate stroke: work satisfaction and predictive factors 
    van der Kemp, Jet; Kruithof, Willeke J.; Nijboer, Tanja C.W.; van Bennekom, Coen A.M.; van Heugten, Caroline; Visser-Meily, Johanna M.A. (Taylor and Francis Ltd., 2019-04-21)
    A large proportion of stroke patients are unable to return to work (RTW), although figures vary greatly. A total of 121 mild-to-moderate stroke patients, who had a paid job at the time of their stroke were included (a) to ...
  • Trends in the risk of cardiovascular disease in women with breast cancer in a Dutch nationwide cohort study 
    Buddeke, Josefien; Gernaat, Sofie A. M.; Bots, Michiel L.; van den Bongard, Desiree H. J. G.; Grobbee, Diederick E.; Vaartjes, Ilonca; Verkooijen, Helena M. (BMJ Publishing Group, 2019-05)
    Objectives: To investigate trends in cardiovascular disease (CVD) risk following breast cancer using national registry data. Methods: A nationwide cohort study was conducted, comprising 163 881 women with in situ (7.6%) ...
  • What are the odds? Prostate metastases to ureter and peritoneum 
    van Roekel, J; Jonges, Trudy GN; Lock, MTWT (BMJ Publishing Group, 2018-01-01)
    In patients with prostate cancer, metastases mostly develop in bone, lung, liver, pleura and adrenal glands. Prostate carcinoma metastases to the ureter are very rare, and the peritoneum is an even rarer site of prostate ...
  • An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity 
    Kopper, Oded; de Witte, Chris J; Lõhmussaar, Kadi; Valle-Inclan, Jose Espejo; Hami, Nizar; Kester, Lennart; Balgobind, Anjali Vanita; Korving, Jeroen; Proost, Natalie; Begthel, Harry; van Wijk, Lise M; Revilla, Sonia Aristín; Theeuwsen, Rebecca; van de Ven, Marieke; van Roosmalen, Markus J; Ponsioen, Bas; Ho, Victor W H; Neel, Benjamin G; Bosse, Tjalling; Gaarenstroom, Katja N; Vrieling, Harry; Vreeswijk, Maaike P G; van Diest, Paul J; Witteveen, Petronella O; Jonges, Trudy; Bos, Johannes L; van Oudenaarden, Alexander; Zweemer, Ronald P; Snippert, Hugo J G; Kloosterman, Wigard P; Clevers, Hans (Nature Research, 2019-05)
    Ovarian cancer (OC) is a heterogeneous disease usually diagnosed at a late stage. Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity of OC are limited and hard to establish. We present ...
  • Advances in percutaneous coronary intervention and antiplatelet therapy in ischemic heart disease 
    Rozemeijer, Rik (Utrecht University, 2019-09-10)
    The present thesis has two principal aims: 1) to evaluate the clinical performance of a novel reservoir-based elution-technology and 2) to gain knowledge about optimizing dual antiplatelet therapy in patients with ischemic ...
  • Masticatory function in patients treated for oral cancer 
    de Groot, Reilly Jeremy (Utrecht University, 2019-09-03)
    This thesis describes the effect of oral oncological intervention on masticatory performance. It represents an attempt to study many factors that either improve or deteriorate masticatory performance, based on both objective ...
  • How complement kills bacteria: A pore way to die 
    Heesterbeek, Dani Anne Cornelia (Utrecht University, 2019-08-29)
    Infections with bacteria form an increasing threat for human health. This is mainly due to the fact that bacteria develop mechanism to resist killing by existing antibiotics. In order to find alternatives to treat infections ...
  • Hepatic Radioembolization in Neuroendocrine Neoplasms 
    Braat, Arthur Johannes Anthonius Theodorus (Utrecht University, 2019-09-20)
    Neuroendocrine Neoplasms (NEN) is a generic term for a class of rare tumours, consisting of an array of many different tumor types. Similar to the trends noticed internationally, in the Dutch population the incidence of ...
  • Consequences of chromosome segregation errors 
    Soto Ruiz De La Torre, Mar (Utrecht University, 2019-08-29)
    Errors in chromosome segregation contribute to tumor heterogeneity and evolution by driving karyotype diversification. However, it is poorly understood how cancer cells tolerate abnormal karyotypes so well. In this thesis ...
  • Perinatal asphyxia: investigating novel neuroprotective agents and optimising current pharmacotherapy 
    Favié, Laurentius Martinus Adrianus (Utrecht University, 2019-09-05)
    This thesis describes research into potential neuroprotective agents in children born with a severe oxygen shortage at birth (perinatal asphyxia). Standard treatment for this condition is therapeutic hypothermia. During ...
  • Autoimmunity in schizophrenia: culprit or bystander? 
    van Mierlo, Hans Christian (Utrecht University, 2019-08-28)
    In chapter 1 an overview of the literature that links schizophrenia and the immune system is given. Previous studies have reported an increased prevalence of antinuclear antibodies in patients with schizophrenia. In chapter ...
  • Healthy and Sustainable Diets: Finding co-benefits and trade-offs for the Netherlands 
    Biesbroek, Sander (Utrecht University, 2019-09-17)
    This thesis investigated the association between diet-related environmental impact and health. Data were from 40,000 Dutch participants enrolled in the EPIC-NL cohort with available dietary data at baseline (1993-1997) and ...
  • Selecting and evaluating decision-making strategies in the intensive care unit: A systematic review 
    Kerckhoffs, Monika C.; Kant, Matthijs; van Delden, Johannes J. M.; Hooft, Lotty; Kesecioglu, Jozef; van Dijk, Diederik (Elsevier, 2019-06)
    Purpose Many patients in the Intensive Care Unit (ICU) die after a decision to withhold or withdraw treatment. To ensure that for each patient the appropriate decision is taken, a careful decision-making process is required. ...
  • The Stability of Treatment Preferences Among Patients With Advanced Cancer 
    Jabbarian, Lea J.; Maciejewski, Renee C.; Maciejewski, Paul K.; Rietjens, Judith A. C.; Korfage, Ida J.; van der Heide, Agnes; van Delden, Johannes J. M.; Prigerson, Holly G. (Elsevier, 2019-06)
    Context: Stability of patients' treatment preferences has important implications for decisions about concurrent and future treatment. Objectives: To examine the stability of treatment preferences and correlates among ...
  • An ethics framework and practical guidance for post-trial access to an RSV maternal vaccine 
    Mazur, Natalie I.; Bont, Louis J.; van Delden, Johannes J. M.; Omer, Saad B. (Elsevier Limited, 2019-06)
  • Disease burden of varicella versus other vaccine-preventable diseases before introduction of vaccination into the national immunisation programme in the Netherlands 
    van Lier, Alies; de Gier, Brechje; McDonald, Scott A; Mangen, Marie-Josée J; van Wijhe, Maarten; Sanders, Elisabeth A M; Kretzschmar, Mirjam E; van Vliet, Hans; de Melker, Hester E (Centre Europeen pour la Surveillance Epidemiologique du SIDA, 2019-05)
    IntroductionEstimating burden of disease (BoD) is an essential first step in the decision-making process on introducing new vaccines into national immunisation programmes (NIPs). For varicella, a common vaccine-preventable ...
  • Who drops out and when?: Predictors of non-response and loss to follow-up in a longitudinal cohort study among STI clinic visitors 
    van Wees, Daphne A; den Daas, Chantal; Kretzschmar, Mirjam E E; Heijne, Janneke C M (Public Library of Science, 2019-06-01)
    INTRODUCTION: Response rates in health research are declining, and low response rates could result in biased outcomes when population characteristics of participants systematically differ from the non-respondents. Few ...