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Now showing items 24101-24120 of 40729

The treatment of ocular hypotony after trabeculectomy with a scleral lens: A case series

Elving-Kokke, K. H.; Sas-Meertens, M. A., V; de Beer, F. M.; van Rijn, L. J.; de Boer, J. H.; Visser, E-S (Elsevier, 2019-02)

Purpose Ocular hypotony after trabeculectomy may be treated medically, surgically and with a tamponade. Three cases are reported in which a scleral lens was applied to treat ocular hypotony after mitomycin C (MMC) augmented ...
Predicting uveitis in juvenile idiopathic arthritis: from biomarkers to clinical practice

Haasnoot, Anne-Mieke J. W.; Kuiper, Jonas J. W.; de Boer, Joke H. (Taylor and Francis Ltd., 2019-06-03)

Introduction: Uveitis is a sight-threatening eye inflammation and common manifestation of juvenile idiopathic arthritis (JIA). New biomarkers that can predict uveitis are needed to alleviate personalized clinical screening. ...
Gender differences of patients at-risk for psychosis regarding symptomatology, drug use, comorbidity and functioning - Results from the EU-GEI study

EU-GEI High Risk Study Group (Cambridge University Press, 2019-06)

BACKGROUND: Gender differences in symptomatology in chronic schizophrenia and first episode psychosis patients have often been reported. However, little is known about gender differences in those at risk of psychotic ...
Transient and chronic childhood immune thrombocytopenia are distinctly affected by Fc-γ receptor polymorphisms

Schmidt, David E; Heitink-Pollé, Katja M J; Laarhoven, Annemieke G; Bruin, Marrie C A; Veldhuisen, Barbera; Nagelkerke, Sietse Q; Kuijpers, Taco W; Porcelijn, Leendert; van der Schoot, C Ellen; Vidarsson, Gestur; de Haas, Masja (The American Society of Hematology, 2019-07-09)

In childhood immune thrombocytopenia (ITP), anti-platelet autoantibodies mediate platelet clearance through Fc-g receptor (FcgR)–bearing phagocytes. In 75% to 90% of patients, the disease has a transient, self-limiting ...
A diagnostic algorithm for the surveillance of deep surgical site infections after colorectal surgery

Mulder, Tessa; Kluytmans-van den Bergh, Marjolein F. Q.; van Mourik, Maaike S. M.; Romme, Jannie; Crolla, Rogier M. P. H.; Bonten, Marc J. M.; Kluytmans, Jan A. J. W. (Cambridge University Press, 2019-05)

Surveillance of surgical site infections (SSIs) is important for infection control and is usually performed through retrospective manual chart review. The aim of this study was to develop an algorithm for the surveillance ...
Molecular tumour boards and molecular diagnostics for patients with cancer in the Netherlands: experiences, challenges, and aspirations

Willemsen, Annelieke E C A B; Krausz, Sarah; Ligtenberg, Marjolijn J L; Grünberg, Katrien; Groen, Harry J M; Voest, Emile E; Cuppen, Edwin P J G; van Laarhoven, Hanneke W M; van Herpen, Carla M L (Springer Nature, 2019-07-02)

Advances in molecular tumour diagnostics and the number of targeted therapies increase rapidly. Molecular tumour boards (MTBs) are designated to interpret these data and provide clinical recommendations. Not all patients ...
Early divergence of mutational processes in human fetal tissues

Kuijk, Ewart; Blokzijl, Francis; Jager, Myrthe; Besselink, Nicolle; Boymans, Sander; Chuva de Sousa Lopes, Susana M; van Boxtel, Ruben; Cuppen, Edwin (American Association for the Advancement of Science, 2019-05)

A developing human fetus needs to balance rapid cellular expansion with maintaining genomic stability. Here, we accurately quantified and characterized somatic mutation accumulation in fetal tissues by analyzing individual ...
Investigating the stratified efficacy and safety of pharmacological blood pressure-lowering: an overall protocol for individual patient-level data meta-analyses of over 300 000 randomised participants in the new phase of the Blood Pressure Lowering Treatment Trialists' Collaboration (BPLTTC)

Blood Pressure Lowering Treatment Trialists' Collaboration (BMJ Publishing Group, 2019-05)

Introduction Previous research from the Blood Pressure Lowering Treatment Trialists' Collaboration (BPLTTC) and others has shown that pharmacological blood pressure (BP)- lowering substantially reduces the risk of major ...
Clinical Manifestations, Prognosis, and Vaccination Status of Patients With Rubella Virus-Associated Uveitis

Groen-Hakan, Fahriye; van de Laar, Suzanne; van der Eijk-Baltissen, Annemiek A.; ten Dam-van Loon, Ninette; de Boer, Joke; Rothova, Aniki (Elsevier, 2019-06)

PURPOSE: To assess the clinical and laboratory manifestations and vaccination status of uveitis patients positive for Rubella virus (RV) in aqueous humor and investigate its relationship to Fuchs Uveitis Syndrome (FUS). ...
CXCR4 mutations in lymphoplasmacytic lymphoma lead to altered CXCR4 expression

Hiemcke-Jiwa, Laura S.; Leguit, Roos J.; Jiwa, N. Mehdi; Huibers, Manon M. H.; Minnema, Monique C. (Wiley-Blackwell, 2019-06-01)
The Etiology of Intraocular Inflammation in HIV Positive and HIV Negative Adults at a Tertiary Hospital in Cape Town, South Africa

Smit, Derrick P.; Esterhuizen, Tonya M.; Meyer, David; de Boer, Joke H.; de Groot-Mijnes, Jolanda D.F. (Informa Healthcare, 2019-02-17)

Purpose: To describe the patterns of uveitis in South Africa. Methods: Prospective cross-sectional study. Results: One hundred and six patients were enrolled and 37.7% had human immune-deficiency virus (HIV) infection. ...
Is mid-upper arm circumference in Dutch children useful in identifying obesity?

Talma, Henk; Van Dommelen, Paula; Schweizer, Joachim J.; Bakker, Boudewijn; Kist-Van Holthe, Joana E.; Chinapaw, J. Mai M.; Hirasing, Remy A. (BMJ Publishing Group, 2019-02-01)

Background Mid-upper arm circumference (MUAC) is suggested as being a valid measure in detecting overweight/obesity in children and adolescents, due to the strong relation with weight. We examined this relation and compared ...
Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells

Fenderico, Nicola; van Scherpenzeel, Revina C.; Goldflam, Michael; Proverbio, Davide; Jordens, Ingrid; Kralj, Tomica; Stryeck, Sarah; Bass, Tarek Z.; Hermans, Guy; Ullman, Christopher; Aastrup, Teodor; Gros, Piet; Maurice, Madelon M. (Nature Publishing Group, 2019-01-21)

Wnt-induced β-catenin-mediated transcription is a driving force for stem cell self-renewal during adult tissue homeostasis. Enhanced Wnt receptor expression due to mutational inactivation of the ubiquitin ligases RNF43/ZNRF3 ...
Renal tubular effects of prolonged therapy with the GLP-1 receptor agonist lixisenatide in patients with type 2 diabetes mellitus

Tonneijck, Lennart; Muskiet, Marcel H.A.; Blijdorp, Charles J.; Smits, Mark M.; Twisk, Jos W.; Kramer, Mark H.H.; Danser, A. H.J.; Diamant, Michaela; Joles, Jaap A.; Hoorn, Ewout J.; van Raalte, Daniël H. (American Physiological Society, 2019-02-01)

Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) are well-established glucose-lowering drugs for type 2 diabetes mellitus (T2DM) management. Acute GLP-1RA administration increases urinary excretion of sodium and ...
Age-related distribution and dynamics of T-cells in blood and lymphoid tissues of goats

Baliu-Piqué, Mariona; Kurniawan, Henry; Ravesloot, Lars; Verheij, Myrddin W.; Drylewicz, Julia; Lievaart-Peterson, Karianne; Borghans, José A.M.; Koets, Ad; Tesselaar, Kiki (Elsevier, 2019-04-01)

Neonatal mammals have increased disease susceptibility and sub-optimal vaccine responses. This raises problems in both humans and farm animals. The high prevalence of paratuberculosis in goats and the lack of an effective ...
Homogeneous B1 + for bilateral breast imaging at 7 T using a five dipole transmit array merged with a high density receive loop array

Krikken, Erwin; Steensma, Bart R.; Voogt, Ingmar J.; Luijten, Peter R.; Klomp, Dennis W.J.; Raaijmakers, Alexander J.E.; Wijnen, Jannie P. (John Wiley & Sons Inc., 2019-02)

To explore the use of five meandering dipole antennas in a multi-transmit setup, combined with a high density receive array for breast imaging at 7 T for improved penetration depth and more homogeneous B1 field. Five ...
Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry

Böttcher, Chotima; Schlickeiser, Stephan; Sneeboer, Marjolein A.M.; Kunkel, Desiree; Knop, Anniki; Paza, Evdokia; Fidzinski, Pawel; Kraus, Larissa; Snijders, Gijsje J.L.; Kahn, René S.; Schulz, Axel R.; Mei, Henrik E.; Hol, Elly M.; Siegmund, Britta; Glauben, Rainer; Spruth, Eike J.; de Witte, Lot D.; Priller, Josef; NBB-Psy (Nature Research, 2019-01-01)

Microglia, the specialized innate immune cells of the CNS, play crucial roles in neural development and function. Different phenotypes and functions have been ascribed to rodent microglia, but little is known about human ...
Management of patients with unruptured intracranial aneurysms

Rinkel, Gabriel J.E. (Lippincott Williams & Wilkins, 2019-02-01)

PURPOSE OF REVIEW: Intracranial aneurysms are frequent incidental findings on cranial imaging. The decision for preventive treatment depends on the presumed risk of rupture, the efficacy and risk of complications of ...
Neutropenia in Barth syndrome: characteristics, risks, and management

Steward, Colin G.; Groves, Sarah J.; Taylor, Carolyn T.; Maisenbacher, Melissa K.; Versluys, Birgitta; Newbury-Ecob, Ruth A.; Ozsahin, Hulya; Damin, Michaela K.; Bowen, Valerie M.; McCurdy, Katherine R.; Mackey, Michael C.; Bolyard, Audrey A.; Dale, David C. (Lippincott Williams & Wilkins, 2019-01-01)

Purpose of reviewBarth syndrome (BTHS) is an X-linked disease characterized by defective remodeling of phospholipid side chains in mitochondrial membranes. Major features include neutropenia, dilated cardiomyopathy, motor ...
Children and young people get rheumatic disease too

Egert, Yona; Egert, Tsipi; Costello, Wendy; Prakken, Berent J.; Smith, Eve M.D.; Wulffraat, Nico M. (Elsevier, 2019-01-01)

Now showing items 24101-24120 of 40729