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Secular Trends in Procedural Stroke or Death Risks of Stenting Versus Endarterectomy for Symptomatic Carotid Stenosis A Pooled Analysis of Randomized Trials

Müller, Mandy D; von Felten, Stefanie; Algra, Ale; Becquemin, Jean-Pierre; Bulbulia, Richard; Calvet, David; Eckstein, Hans-Henning; Fraedrich, Gustav; Halliday, Alison; Hendrikse, Jeroen; Howard, George; Gregson, John; Jansen, Olav; Brown, Martin M; Mas, Jean-Louis; Brott, Thomas G; Ringleb, Peter A; Bonati, Leo H (Lippincott Williams & Wilkins, 2019-08)

BACKGROUND: Over the past decades, stroke risk associated with carotid disease has decreased, reflecting improvements in medical therapy and a more rigorous control of vascular risk factors. It is less clear whether the ...
Prevention of postoperative delirium in elderly patients planned for elective surgery: systematic review and meta-analysis

Janssen, T L; Alberts, A R; Hooft, L; Mattace-Raso, Fus; Mosk, C A; van der Laan, L (Dove Medical Press Ltd., 2019-06-19)

Introduction: Vulnerable or "frail" patients are susceptible to the development of delirium when exposed to triggers such as surgical procedures. Once delirium occurs, interventions have little effect on severity or duration, ...
Factors Contributing to Cancer-Related Muscle Wasting During First-Line Systemic Treatment for Metastatic Colorectal Cancer

Derksen, Jeroen W G; Kurk, Sophie A; Oskam, Marieke J; Peeters, Petra H M; Punt, Cornelis J A; Koopman, Miriam; May, Anne M (Oxford University Press, 2019-06)

Background: Increasing evidence indicates that loss of muscle mass is associated with adverse outcomes in metastatic colorectal cancer. Here, we investigate which demographic, lifestyle- (smoking), tumor-, and treatment-related ...
Hippocampal sulcal cavities prevalence, risk factors and association with cognitive performance. The SMART-Medea study and PREDICT-MR study

SMART Study Group (Springer New York, 2019-08)

Hippocampal sulcal cavities (HSCs) are frequently observed on MRI, but their etiology and relevance is unclear. HSCs may be anatomical variations, or result from pathology. We assessed the presence of HSCs, and their ...
Substitutions between dairy products and risk of stroke: Results from the European Investigation into Cancer and Nutrition-Netherlands (EPIC-NL) cohort

Laursen, Anne Sofie D.; Sluijs, Ivonne; Boer, Jolanda M.A.; Verschuren, W. M.Monique; Van Der Schouw, Yvonne T.; Jakobsen, Marianne U. (Cambridge University Press, 2019-06-28)

The association between intake of different dairy products and the risk of stroke remains unclear. We therefore investigated substitutions between dairy product subgroups and risk of stroke. We included 36,886 Dutch men ...
Roux-Y Gastric Bypass and Sleeve Gastrectomy directly change gut microbiota composition independent of surgery type

Paganelli, Fernanda L.; Luyer, Misha; Hazelbag, C. Marijn; Uh, Hae Won; Rogers, Malbert R.C.; Adriaans, Danielle; Berbers, Roos Marijn; Hendrickx, Antoni P.A.; Viveen, Marco C.; Groot, James A.; Bonten, Marc J.M.; Fluit, Ad C.; Willems, Rob J.L.; Leavis, Helen L. (Nature Publishing Group, 2019-07-29)

Bariatric surgery in morbid obesity, either through sleeve gastrectomy (SG) or Roux-Y gastric bypass (RYGB), leads to sustainable weight loss, improvement of metabolic disorders and changes in intestinal microbiota. Yet, ...
Mogelijkheden van 3D-printen in de geneeskunde: 5 jaar later

Visser, Jetze; Melchels, Ferry P W; Weinans, Harrie; Kruyt, Moyo C; Malda, Jos (Bohn Stafleu van Loghum, 2019-06-05)

5 years ago, we described the emergence of 3D printing in medicine. It was about 3D printing of anatomical structures, patient-specific drilling guides, cutting templates and implants and printing of living cells, growth ...
The Trials within Cohorts design faced methodological advantages and disadvantages in the exercise oncology setting

Gal, Roxanne; Monninkhof, Evelyn M; van Gils, Carla H; Groenwold, Rolf H H; van den Bongard, Desirée H J G; Peeters, Petra H M; Verkooijen, Helena M; May, Anne M (Elsevier, 2019-09)

OBJECTIVE: The Trials within Cohorts (TwiCs) design is an alternative for pragmatic RCTs and might overcome disadvantages as difficult recruitment, drop-out after randomization to control and contamination. We investigated ...
Impetigo incidence and treatment: a retrospective study of Dutch routine primary care data

Loadsman, Madelyn E.N.; Verheij, Theo J.M.; van der Velden, Alike W. (Oxford University Press, 2019-07-31)

BACKGROUND: There is a lack of recently published data on impetigo presentation incidence and treatment practices in the routine Western European primary care setting. OBJECTIVES: To investigate impetigo incidence, treatments ...
Fosfomycin-Trometamol for Urinary Tract Infections in Kidney Transplant Recipients

Ten Doesschate, T; van Werkhoven, C H; Meijvis, S C; Stalenhoef, J E; van Zuilen, A D; de Vries, A P J; Bonten, M J M (Lippincott Williams & Wilkins, 2019-06-01)

BACKGROUND: The treatment of urinary tract infections (UTIs) in kidney transplant recipients (KTRs) with oral antibiotics is complicated by increasing resistance to trimethoprim-sulfamethoxazole, amoxicillin/clavulanic ...
Trajectories of Limitations in Instrumental Activities of Daily Living in Frail Older Adults With Vision, Hearing, or Dual Sensory Loss

Mueller-Schotte, Sigrid; Zuithoff, Nicolaas P.A.; van der Schouw, Yvonne T.; Schuurmans, Marieke J.; Bleijenberg, Nienke (Oxford University Press, 2019-06)

BACKGROUND: This study investigated the trajectories of decline in individual instrumental activities of daily living (IADL) with aging and the effect of hearing loss, vision loss, or dual sensory loss on these trajectories ...
Detection of atrial fibrillation in primary care

Kaasenbrood, Femke (Utrecht University, 2019-10-10)

Effectiveness and feasibility of two strategies to screen for AF in primary care. In chapter2 we examined a programmatic approach in which research nurses screened for AF during influenza vaccination in primary care ...
Online treatment adaptation strategies for the 1.5T MR-linac: first implementation and evaluation for lymph node oligometastases

Winkel, Dennis (Utrecht University, 2019-10-17)

Treatment planning is an important aspect of radiotherapy to make sure adequate target coverage is achieved, without compromising tolerances of surrounding healthy tissue. Automated treatment planning has contributed to ...
A new water calorimeter for modern radiotherapy

de Prez, Leon Armand (Utrecht University, 2019-09-26)

Accuracy in radiotherapy is of vital importance for individual patient treatment and for clinical trials on which patient treatments. There is a continuous demand for improvement of dosimetry methods and adaption of dosimetry ...
Imaging biomarker development and optimization of 195mPt-cisplatin and 68Ga-DOTATATE

Aalbersberg, Else Aagje (Utrecht University, 2019-10-29)

Cancer affects people worldwide, causing approximately 9.6 million deaths in 2018 globally. Although cancer remains a deadly disease, the survival rate for all cancers has significantly increased over time. This increase ...
Peer feedback to promote deep learning in online education: Unraveling the process

Filius, Renée Marianne (Utrecht University, 2019-05-23)

Universities aim for deep learning. Two trends may threaten the achievement of deep learning, namely the massification of students and the increasing choice for online education by universities. Considering these trends, ...
Comparison of infliximab serum levels between venous and capillary blood in paediatric IBD patients using novel blood sampling technology

Zijlstra, M; Jongsma, Myrthe; de Vries, Annick; Schaap, T.; Bloem, Karien; de Ridder, Lissy (2019-03)

P440
New insight into vitamin B6 metabolism and related diseases

Ramos, R.J.J.F. (Utrecht University, 2019-10-10)

Vitamin B6 is present in the human body as six structurally related vitamers: pyridoxal (PL), pyridoxine (PN), pyridoxamine (PM), and their respective 5’-phosphate esters pyridoxal 5’-phosphate (PLP), pyridoxine 5’-phosphate ...
Supporting caregivers of people with Amyotrophic Lateral Sclerosis

de Wit, Jessica (Utrecht University, 2019-10-09)

Informal caregivers play a crucial role in the care for people with Amyotrophic Lateral Sclerosis (ALS). ALS is a motor neuron disease which leads to muscle weakness and respiratory failure. During the disease course ...
Large-scale brain connectivity in schizophrenia in relation to auditory verbal hallucinations and familial liability

Chang, Xiao (Utrecht University, 2019-08-28)

The research in this thesis aims to assess functional and structural connectivity in schizophrenia using MRI techniques, and to contribute new evidence to elucidate connectivity abnormalities in schizophrenia in relation ...

Now showing items 23981-24000 of 40729