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Technical advances paving the way for non-invasive renal perfusion MRI

Bones, Isabell Katrin (Utrecht University, 2021-10-07)

Kidneys need healthy blood supply to perform their function and clean the body from waste products and excess water. Hence, monitoring of renal perfusion may provide valuable information about renal function. Having ...
Equal access to breast cancer genetic counseling and testing : Development and implementation of a health literacy training program for surgical oncologists and specialized nurses

Doelen, Jeanine Adriana Maria van der (Utrecht University, 2021-09-28)

Patients with a lower educational or a migrant background seem to have poorer access to breast cancer genetic counseling and testing. Referral is not always adequately discussed with these groups of patients, and limited ...
Interventions for preventing falls and fall-related fractures in community-dwelling older adults: A systematic review and network meta-analysis

Dautzenberg, Lauren; Beglinger, Shanthi; Tsokani, Sofia; Zevgiti, Stella; Raijmann, Renee C. M. A.; Rodondi, Nicolas; Scholten, Rob J. P. M.; Rutjes, Anne W. S.; Nisio, Marcello Di; Emmelot-Vonk, Marielle; Tricco, Andrea C.; Straus, Sharon E.; Thomas, Sonia; Bretagne, Lisa; Knol, Wilma; Mavridis, Dimitris; Koek, Huiberdina L. (Wiley, 2021-07)

Objective: To compare the effectiveness of single, multiple, and multifactorial interventions to prevent falls and fall-related fractures in community-dwelling older persons. Methods: MEDLINE, Embase, and Cochrane Central ...
Medication review interventions to reduce hospital readmissions in older people

Dautzenberg, Lauren; Bretagne, Lisa; Koek, Huiberdina L.; Tsokani, Sofia; Zevgiti, Stella; Rodondi, Nicolas; Scholten, Rob J. P. M.; Rutjes, Anne W.; Nisio, Marcello Di; Raijmann, Renee C. M. A.; Emmelot-Vonk, Marielle; Jennings, Emma L. M.; Dalleur, Olivia; Mavridis, Dimitris; Knol, Wilma (Wiley, 2021-06)

Objective: To assess the efficacy of medication review as an isolated intervention and with several co-interventions for preventing hospital readmissions in older adults. Methods: Ovid MEDLINE, Embase, The Cochrane Central ...
Improving outcome assessment covering functions, activities and participation in patients with haemophilia

Kuijlaars, Isolde Aldegonda Rudolf (Utrecht University, 2021-10-14)

Joint bleeds in persons with haemophilia (PWH) result in haemophilic arthropathy, which has an impact on daily activities and participation in school-, work- and leisure activities. Assessing outcomes is essential to ...
Methodological challenges of complex proactive primary care programs for older people

Smit, Aleida Catharina (Utrecht University, 2021-09-14)

Methodological challenges of complex proactive primary care programs for older people The clinical practice is continuously changing as a result of an ageing population and the increase of multimorbidity and frailty. ...
Mechanical control of epithelial cell division

Donker, Lisa (Utrecht University, 2021-09-16)

Epithelia form essential barriers that protect tissues from the external environment, yet at the same time display high rates of cellular turnover. To ensure the integrity of this barrier while preventing overgrowth, ...
Hematopoiesis in the developing zebrafish embryo

Franke, Sasja (Utrecht University, 2021-09-07)

This thesis describes the use of zebrafish, Danio rerio, to unravel the complexity of hematopoiesis in the developing embryo with an emphasis on the role of two phosphatases. In chapter 1, we provide a background for the ...
Intrafraction motion tracking for MR-Linac prostate radiotherapy

Muinck Keizer, Daan Maarten de (Utrecht University, 2021-09-14)

With the clinical introduction of linear accelerators combined with magnetic resonance imaging, such as the 1.5T MR-Linac, new opportunities to further improve radiotherapy treatments arrived. The fact that fast 3D imaging ...
Childhood cancer related hearing loss and tinnitus

Meijer, Annelot Jacobine Maxime (Utrecht University, 2021-09-30)

Ototoxicity (hearing loss, tinnitus and/or vertigo) is a serious adverse event of childhood cancer treatment that may have a severe negative impact on quality of life. Up until now, studies have mainly focused on identifying ...
Detection of cardiovascular disease and cardiovascular risk factors in a changing world

Boer, Annemarijn Rachel de (Utrecht University, 2021-09-16)

In the past 40 years, the cardiovascular landscape has changed with dropping cardiovascular mortality rates due to improvements in primary and secondary prevention of cardiovascular disease (CVD) and more effective treatment ...
Enhanced recovery after robot-assisted minimally invasive esophagectomy

Kingma, Berend Feike (Utrecht University, 2021-09-21)

Esophagectomy is the core of curative treatment for esophageal cancer, achieving a 5-year survival rate of 40-50% when combined with neoadjuvant treatment. Previous single-center studies showed that robot-assisted minimally ...
Diamond Blackfan anemia & other hereditary red cell disorders: spotting phenotypes

Dooijeweert, Birgit van (Utrecht University, 2021-09-23)

Research in this thesis was conducted to contribute to the phenotypic characterization of hereditary anemias, in particular of Diamond-Blackfan anemia (DBA). Phenotyping is at the root of recognizing and understanding ...
Technical developments for quantitative and motion resolved MR-guided radiotherapy

Bruijnen, Tom (Utrecht University, 2021-09-02)

Radiotherapy is a non-invasive therapeutic modality that uses highly targeted radiation to treat cancer. The success of the treatment is to a large extent related to the precision of the radiation delivery. The precision ...
Old means for new ends : Optimizing the treatment of urinary tract infections

Doesschate, Thijs ten (Utrecht University, 2021-10-07)

Urinary tract infections (UTIs) are common bacterial infections that are at most inconvenient for some patients while they seriously impede health for others. The first part of this thesis addresses the antibiotic treatment ...
Rotavirus vaccination for infants with medical risk conditions

Dongen, Josephine Alette Peihrien van (Utrecht University, 2021-09-28)

In the RIVAR study the full safety-effectiveness-implementation spectrum of rotavirus vaccination for infants with MRC was evaluated. Therefore, for this specific patient population, guided recommendations can be made. ...
Laryngectomy: complications & survival

Pézier, Thomas Francis Robert (Utrecht University, 2021-09-09)

The larynx is the midline throat structure commonly referred to as the “voice box. It is a complex structure critical to breathing, speaking and the prevention of aspiration (choking). Surgery to remove the larynx is called ...
Insights in Diagnostic and Prognostic Biomarkers in Interstitial Lung Disease

Moll, Sofia Ana (Utrecht University, 2021-09-09)

Interstitial lung diseases (ILDs) are a diverse group of rare lung diseases, characterized by inflammation and/or scarring (fibrosis) of the lungs. The current principles of diagnosis and treatment focusses on the recognition ...
Squaring the circle: The expression and function of axon guidance circular RNAs during neuronal development

Rossum, Daniëlle Samantha van (Utrecht University, 2021-09-02)

In this thesis we investigated the expression and function of axon guidance circular RNAs (circRNAs) in the developing (mouse) brain. We tested and optimized various assays to measure, label and overexpress or knockdown ...
Safety and efficacy of cardiovascular medication in women and men; the added value of clinical care data

Bots, Sophie Heleen (Utrecht University, 2021-09-02)

Women and men are different. This may seem obvious, but cardiovascular research too often treats women and men as interchangeable. Due to this, there is a lack of sex-specific knowledge about optimal treatment for patients ...

Now showing items 21161-21180 of 40729