Every year about 600 children are diagnosed with cancer in the Netherlands. The different forms of cancer can be divided into three main subtypes: haematological, solid or neurological tumours. Different treatment modalities ...

Tinnitus is the perception of sound without an external stimulus, often experienced as a ringing, buzzing sound. It has a prevalence ranging from 10 to 30% of the general population with up to 3% of people with tinnitus ...

Cardiovascular diseases are the leading cause of death globally, accounting for approximately 32% of all deaths. These diseases, such as ischemic heart disease, stroke, and venous thromboembolism, are characterized by ...

Worldwide, the population is ageing rapidly. Multimorbidity and polypharmacy become more prevalent with advancing age, increasing the risk of receiving potential inappropriate prescriptions (PIPs) and their associated ...

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy characterized by life-threatening ventricular arrhythmias as one of the first disease presentations. Although no cure exists for ARVC, ...

Breast cancer prognosis has improved over the last two decades for an important part due to the administration of adjuvant systemic therapy. It has become evident that tumor biology, reflected by the different molecular ...

People with haemophilia A (PwHA) have a deficiency of coagulation factor VIII and experience recurrent bleeding. Currently, PwHA are treated effectively with drugs such as FVIII products or emicizumab. Measuring and ...

The ultimate potential of the MR-linac is real-time adaptive MR-guided radiotherapy (aMRgRT), i.e. adapt the radiation plan in real-time according to real-time 3D motion estimates. One of the major technical roadblocks ...

In this thesis I have described the use of different point-of-care tests (POCTs) on respiratory syncytial virus (RSV) as well as the burden and dynamics of respiratory viruses in infants. In part one of the thesis I ...

Most people at times experience physical symptoms such as pain, fatigue or dizziness. Surveys show that approximately 90% of the Dutch general population experienced at least one physical symptom in the past two weeks. ...