Placebo effects, also known as context effects, can be partly explained by expectations and trust between patient and professional. Context effects play an important role in recovery from illnesses that are characterised ...

The RELIEF project’s main aim was to improve pain management of children with cancer at home. To achieve this, three sub-aims were formulated: first, to explore pain prevalence in children with cancer at home (chapter ...

Obesity is one of the greatest global contemporary challenges to public health. It is associated with an increased risk of numerous health problems including metabolic syndrome as well as several types of cancer. In addition, ...

Columnar cell lesions of the breast are proposed as the earliest recognizable precursor lesions of low grade breast cancer. The lesions are characterized by cystically enlarged terminal duct lobular units with monotonous ...

Awareness increases that tumors are not a homogenous collection of cells but instead form a micro-environment together with non-cancer cells. Novel anti-cancer therapies such as immunotherapy target this micro-environment ...

Antibiotic resistance is a growing problem, leading to ineffective antibiotic treatments, causing bacterial infections to be lethal again. Therefore, new alternatives are needed to fight bacterial infections. Targeting ...

Adult stem cell (ASC)-derived organoids are miniature replicas of human epithelial organs. These organoids represent the molecular characteristic of their epithelium of origin, and thus, they can be used as proxies to study ...

In this thesis we explored the clinical and genetic risk factors for idiopathic multifocal choroiditis (MFC). MFC is a rare ocular disease affecting the choroid in the posterior pole of the eye. This relapsing disease ...

There are few experiences as trying as preterm birth. For both the parent and the child, the first few weeks of life are mired by uncertainty, adversity, and (subjective) stress. The complex and diverse effects of postnatal ...

The interaction of a myriad of molecular factors is necessary for proper development of mDA circuitry. Although significant progress has been made in uncovering the mechanisms involved in mDA neuron development, our ...