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Now showing items 19761-19780 of 40729

Artifact Processing Methods Influence on Intraoperative Hypotension Quantification and Outcome Effect Estimates

Pasma, Wietze; Peelen, Linda M; van Buuren, Stef; van Klei, Wilton A; de Graaff, Jurgen C (Lippincott Williams & Wilkins, 2020-04-01)

BACKGROUND: Physiologic data that is automatically collected during anesthesia is widely used for medical record keeping and clinical research. These data contain artifacts, which are not relevant in clinical care, but may ...
Does respiratory syncytial virus lower respiratory illness in early life cause recurrent wheeze of early childhood and asthma? Critical review of the evidence and guidance for future studies from a World Health Organization-sponsored meeting

Driscoll, Amanda J.; Arshad, S. Hasan; Bont, Louis; Brunwasser, Steven M.; Cherian, Thomas; Englund, Janet A.; Fell, Deshayne B.; Hammitt, Laura L.; Hartert, Tina V.; Innis, Bruce L.; Karron, Ruth A.; Langley, Gayle E.; Mulholland, E. Kim; Munywoki, Patrick K.; Nair, Harish; Ortiz, Justin R.; Savitz, David A.; Scheltema, Nienke M.; Simões, Eric A.F.; Smith, Peter G.; Were, Fred; Zar, Heather J.; Feikin, Daniel R. (Elsevier, 2020-03-04)

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection (LRTI) and hospitalization in infants and children globally. Many observational studies have found an association between RSV LRTI ...
Zirconium-89 labelled rituximab PET-CT imaging of Graves' orbitopathy

de Keizer, Bart; Laban, Kamil G; Kalmann, Rachel (Springer-Verlag, 2020-03)
gamma delta T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity

Janssen, Anke; Villacorta Hidalgo, José; Beringer, Dennis X; van Dooremalen, Sanne F.J.; Fernando, Febilla; van Diest, Eline; Terrizzi, Antonela R; Bronsert, Peter; Kock, Sylvia; Schmitt-Graeff, Annette; Werner, Martin; Heise, Kerstin; Follo, Marie; Straetemans, Trudy; Sebestyen, Zsolt; Chudakov, Dmitriy M; Kasatskaya, Sofya A; Frenkel, Felix E; Ravens, Sarina; Spierings, Eric; Prinz, Immo; Küppers, Ralf; Malkovsky, Miroslav; Fisch, Paul; Kuball, Jurgen (American Association for Cancer Research Inc., 2020-04)

Γδ T cells in human solid tumors remain poorly defined. Here, we describe molecular and functional analyses of T-cell receptors (TCR) from tumor-infiltrating γδ T lymphocytes (γδ TIL) that were in direct contact with tumor ...
TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

Johanna, Inez; Hernández-López, Patricia; Heijhuurs, Sabine; Bongiovanni, Laura; de Bruin, Alain; Beringer, Dennis; van Dooremalen, Sanne; Shultz, Leonard D; Ishikawa, Fumihiko; Sebestyen, Zsolt; Straetemans, Trudy; Kuball, Jürgen (Oxford University Press, 2020-06-01)

γδT cells play an important role in cancer immunosurveillance and are able to distinguish malignant cells from their healthy counterparts via their γδTCR. This characteristic makes γδT cells an attractive candidate for ...
Non-alcoholic fatty liver disease, a new and growing risk indicator for cardiovascular disease

Janssen, Arne; Grobbee, Diederick E; Dendale, Paul (Oxford University Press, 2020-07-01)
De novo heterozygous missense and loss-of-function variants in CDC42BPB are associated with a neurodevelopmental phenotype

Chilton, Ilana; Okur, Volkan; Vitiello, Giuseppina; Selicorni, Angelo; Mariani, Milena; Goldenberg, Alice; Husson, Thomas; Campion, Dominique; Lichtenbelt, Klaske D; van Gassen, Koen; Steinraths, Michelle; Rice, Jennifer; Roeder, Elizabeth R; Littlejohn, Rebecca O; Srour, Myriam; Sebire, Guillaume; Accogli, Andrea; Héron, Delphine; Heide, Solveig; Nava, Caroline; Depienne, Christel; Larson, Austin; Niyazov, Dmitriy; Azage, Meron; Hoganson, George; Burton, Jennifer; Rush, Eric T; Jenkins, Janda L; Saunders, Carol J; Thiffault, Isabelle; Alaimo, Joseph T; Fleischer, Julie; Groepper, Daniel; Gripp, Karen W; Chung, Wendy K (John Wiley & Sons Inc., 2020-05)

CDC42BPB encodes MRCKβ (myotonic dystrophy-related Cdc42-binding kinase beta), a serine/threonine protein kinase, and a downstream effector of CDC42, which has recently been associated with Takenouchi-Kosaki syndrome, an ...
Lenalidomide added to standard intensive treatment for older patients with AML and high-risk MDS

Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK) (Springer Nature, 2020-07-01)

More effective treatment modalities are urgently needed in patients with acute myeloid leukemia (AML) of older age. We hypothesized that adding lenalidomide to intensive standard chemotherapy might improve their outcome. ...
Patient-Reported Work Ability During the First Two Years After Rectal Cancer Diagnosis

Couwenberg, Alice M; Intven, Martijn P W; Gregorowitsch, Madelijn Leoniek; Haaring, Cees; van Grevenstein, Wilhelmina; Verkooijen, Helena Marieke (Lippincott Williams & Wilkins, 2020-05)

BACKGROUND: Rectal cancer treatment is associated with substantial short- and longer-term morbidity that may affect patients' ability to work. OBJECTIVE: We evaluated patient-reported work ability during the first 2 years ...
Co-prevalence of extracranial carotid aneurysms differs between European intracranial aneurysm cohorts

van Laarhoven, Constance J.H.C.M.; Pourier, Vanessa E.C.; Lindgren, Antti E.; Vergouwen, Mervyn D.I.; Jääskeläinen, Juha E.; Rinkel, Gabriël J.E.; de Kleijn, Dominique P.V.; de Borst, Gert J. (Public Library of Science, 2020-01-01)

Background and purpose Previously, we showed that co-prevalence of extracranial carotid artery aneurysms (ECAAs) in patients with intracranial aneurysms (IAs) was 2% in a Dutch cohort. In order to obtain more precise ...
Assessing participation of children with acquired brain injury and cerebral palsy: a systematic review of measurement properties

Resch, Christine; Van Kruijsbergen, Mette; Ketelaar, Marjolijn; Hurks, Petra; Adair, Brooke; Imms, Christine; De Kloet, Arend; Piskur, Barbara; Van Heugten, Caroline (Wiley-Blackwell, 2020-04)

AIM: To examine which instruments used to assess participation of children with acquired brain injury (ABI) or cerebral palsy (CP) align with attendance and/or involvement constructs of participation; and to systematically ...
Causes of early death and treatment-related death in newly diagnosed pediatric acute myeloid leukemia: Recent experiences of the Dutch Childhood Oncology Group

Klein, Kim; van Litsenburg, Raphaële R.L.; de Haas, Valérie; Dors, Natasja; van den Heuvel-Eibrink, Marry M.; Knops, Rutger R.G.; Tissing, Wim J.E.; Versluys, Birgitta A.; Zwaan, C. Michel; Kaspers, Gertjan J.L. (Wiley-Liss Inc., 2020-04)

Background: With the current more effective treatment regimens for pediatric acute myeloid leukemia (AML), research on early death (ED), treatment-related mortality (TRM), and toxicity becomes increasingly important. The ...
Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells

Myers, Darienne R.; Norlin, Emilia; Vercoulen, Yvonne; Roose, Jeroen P. (Cell Press, 2019-05-07)

Naive CD4 + T cells are an example of dynamic cell homeostasis: T cells need to avoid autoreactivity while constantly seeing self-peptides, yet they must be primed to react to foreign antigens during infection. The instructive ...
cDC2 and plasmacytoid dendritic cells diminish from tissues of patients with non-Hodgkin orbital lymphoma and idiopathic orbital inflammation

Laban, Kamil G.; Rijken, Rianne; Hiddingh, Sanne; Mertens, Jorre S.; van der Veen, Rob L.P.; Eenhorst, Christine A.E.; Pandit, Aridaman; Radstake, Timothy R.D.J.; de Boer, Joke H.; Kalmann, Rachel; Kuiper, Jonas J.W. (Wiley-VCH Verlag, 2020-04)

Non-Hodgkin orbital lymphoma (NHOL) and idiopathic orbital inflammation (IOI) are common orbital conditions with largely unknown pathophysiology. To investigate the immune cell composition of these diseases, we performed ...
Population Pharmacokinetics and Pharmacodynamics of Ciprofloxacin Prophylaxis in Pediatric Acute Lymphoblastic Leukemia Patients

Sassen, S D T; Mathôt, R A A; Pieters, R; van Westreenen, M; de Haas, V; Kaspers, G J L; van den Bos, C; Tissing, W J E; Te Loo, D M W W; Bierings, M B; van der Sluis, I M; Zwaan, C M (Oxford University Press, 2020-10-15)

Background: Ciprofloxacin is used as antimicrobial prophylaxis in pediatric acute lymphoblastic leukemia (ALL) to decrease infections with gram-negative bacteria. However, there are no clear guidelines concerning prophylactic ...
Nasopharyngeal microbiota profiles in rural Venezuelan children are associated with respiratory and gastrointestinal infections

Verhagen, Lilly M; Rivera-Olivero, Ismar A; Clerc, Melanie; Chu, Mei Ling J N; van Engelsdorp Gastelaars, Jody; Kristensen, Maartje I; Berbers, Guy A M; Hermans, Peter W M; de Jonge, Marien I; de Waard, Jacobus H; Bogaert, Debby (Oxford University Press, 2021-01-15)

BACKGROUND: Recent research suggests that the microbiota affects susceptibility to both respiratory tract infections (RTIs) and gastrointestinal infections (GIIs). In order to optimize global treatment options, it is ...
Transplantation in Children and Adolescents with Acute Lymphoblastic Leukemia from a Matched Donor versus an HLA-Identical Sibling: Is the Outcome Comparable? Results from the International BFM ALL SCT 2007 Study

Balduzzi, Adriana; Dalle, Jean Hugues; Wachowiak, Jacek; Yaniv, Isaac; Yesilipek, Akif; Sedlacek, Petr; Bierings, Marc; Ifversen, Marianne; Sufliarska, Sabina; Kalwak, Krzysztof; Lankester, Arjan; Toporski, Jacek; Di Maio, Lucia; Glogova, Evgenia; Poetschger, Ulrike; Peters, Christina (Elsevier, 2019-11-01)

Eligibility criteria for hematopoietic stem cell transplantation (HSCT) in acute lymphoblastic leukemia (ALL) vary according to disease characteristics, response to treatment, and type of available donor. As the risk profile ...
Emotional and behavioral problems in children with dilated cardiomyopathy

van der Mheen, Malindi; van der Meulen, Marijke H.; den Boer, Susanna L.; Schreutelkamp, Dayenne J.; van der Ende, Jan; de Nijs, Pieter F.A.; Breur, Johannes M.P.J.; Tanke, Ronald B.; Blom, Nico A.; Rammeloo, Lukas A.J.; ten Harkel, Arend D.J.; du Marchie Sarvaas, Gideon J.; Utens, Elisabeth M.W.J.; Dalinghaus, Michiel (Elsevier, 2020-04)

BACKGROUND: Dilated cardiomyopathy (DCM) in children is an important cause of severe heart failure and carries a poor prognosis. Adults with heart failure are at increased risk of anxiety and depression and such symptoms ...
Impact of clinical and haemodynamic factors on coronary flow reserve and invasive coronary flow capacity in non-obstructed coronary arteries: a patient-level pooled analysis of the DEBATE and ILIAS studies

Stegehuis, Valérie Elise; Wijntjens, Gilbert W M; Bax, Matthijs; Meuwissen, Martijn; Chamuleau, Steven A J; Voskuil, Michiel; Koch, Karel T; Di Mario, Carlo; Vrints, Christiaan; Haude, Michael; Board, Ei Statistical; Serruys, Patrick W; Piek, Jan J; van de Hoef, Tim P (Europa Group, 2021-04-02)

AIMS: Coronary flow reserve (CFR) is a physiological index for the assessment of myocardial flow impairment due to focal or microcirculatory coronary artery disease (CAD). Coronary flow capacity (CFC) is another flow-based ...
Late onset of new conduction disturbances requiring permanent pacemaker implantation following TAVI

Kooistra, Nynke H M; van Mourik, Martijn S; Rodríguez-Olivares, Ramón; Maass, Alexander H; Nijenhuis, Vincent J; van der Werf, Rik; Ten Berg, Jurrien M; Kraaijeveld, Adriaan O; Baan, Jan; Voskuil, Michiel; Vis, M Marije; Stella, Pieter R (BMJ Publishing Group, 2020-08)

BACKGROUND: The timing of onset and associated predictors of late new conduction disturbances (CDs) leading to permanent pacemaker implantation (PPI) following transcatheter aortic valve implantation (TAVI) are still ...

Now showing items 19761-19780 of 40729