Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

Now showing items 18941-18960 of 40729

Diagnostic accuracy of multiparametric MRI for local staging of bladder cancer: A systematic review and meta-analysis

Cornelissen, Suzan W E; Veenboer, Paul W; Wessels, Frank J; Meijer, Richard P (Elsevier, 2020-11)

To evaluate diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) for local staging of urothelial bladder carcinoma (UBC), a systematic review was performed. Of 2369 records, 20 studies met the inclusion ...
A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: The ASPEN study

Tam, Constantine S; Opat, Stephen; D'Sa, Shirley; Jurczak, Wojciech; Lee, Hui-Peng; Cull, Gavin; Owen, Roger G; Marlton, Paula; Wahlin, Björn Engelbrekt; Garcia-Sanz, Ramon; McCarthy, Helen; Mulligan, Stephen; Tedeschi, Alessandra; Castillo, Jorge; Czyz, Jaroslaw; Fernández de Larrea, Carlos; Belada, David; Libby, Edward; Matous, Jeffrey V; Motta, Marina; Siddiqi, Tanya; Tani, Monica; Trneny, Marek; Minnema, Monique C; Buske, Christian; Leblond, Veronique; Chan, Wai Y; Schneider, Jingjing Yan; Ro, Sunhee; Cohen, Aileen; Huang, Jane; Dimopoulos, Meletios A (Elsevier, 2020-10-29)

Bruton tyrosine kinase (BTK) inhibition is an effective treatment approach for patients with Waldenström macroglobulinemia (WM). The phase 3 ASPEN study compared the efficacy and safety of ibrutinib, a first-generation BTK ...
Spherical deconvolution with tissue-specific response functions and multi-shell diffusion MRI to estimate multiple fiber orientation distributions (mFODs)

De Luca, Alberto; Guo, Fenghua; Froeling, Martijn; Leemans, Alexander (Academic Press Inc., 2020-11-15)

In diffusion MRI, spherical deconvolution approaches can estimate local white matter (WM) fiber orientation distributions (FOD) which can be used to produce fiber tractography reconstructions. The applicability of spherical ...
Age, pathology and CA-125 are prognostic factors for survival in patients with brain metastases from gynaecological tumours

Nagtegaal, S H J; Hulsbergen, A F C; van Dorst, E B L; Kavouridis, V K; Jessurun, C A C; Broekman, M L D; Smith, T R; Verhoeff, J J C (Elsevier Ireland Ltd, 2020-09)

Background and purpose: Brain metastases originating from gynaecological tumours are a rare phenomenon, but have an increasing incidence due to better targeted therapies. This study aimed to identify factors that predict ...
Prognostic factors for overall survival of stage III non-small cell lung cancer patients on computed tomography: a systematic review and meta-analysis

van Laar, Myra; van Amsterdam, Wouter A C; van Lindert, Anne S R; de Jong, Pim A; Verhoeff, Joost J C (Elsevier Ireland Ltd, 2020-10)

INTRODUCTION: Prognosis prediction is central in treatment decision making and quality of life for non-small cell lung cancer (NSCLC) patients. However, conventional computed tomography (CT) related prognostic factors may ...
Predicting incomplete resection in non-small cell lung cancer preoperatively: a validated nomogram

Rasing, Marnix J A; Peters, Max; Moreno, Amy C; Hofman, Erik F N; Herder, Gerarda J M; Welvaart, Pim W N; Schramel, Franz M N H; Lodeweges, Joyce E; Lin, Steven H; Verhoeff, Joost J C; van Rossum, Peter S N (Elsevier, 2021-03)

Background: Patients who are surgically treated for stage I to III non-small cell lung cancer (NSCLC) have dismal prognosis after incomplete (R1-R2) resection. Our study aimed to develop a prediction model to estimate the ...
Factors Influencing Implementation of Family-Centered Care in a Neonatal Intensive Care Unit

Oude Maatman, Sabine M; Bohlin, Kajsa; Lilliesköld, Siri; Garberg, Håvard T; Uitewaal-Poslawky, Irina; Kars, Marijke C; van den Hoogen, Agnes (Frontiers Media S. A., 2020-05-06)

Background: Approximately 10% of all births worldwide are preterm. Often these infants are admitted at a Neonatal Intensive Care Unit (NICU). The NICU environment with periods of unnatural light, noise and repeated ...
Evaluation showed that stakeholders valued the support provided by the Implementing Pediatric Advance Care Planning Toolkit

Fahner, Jurrianne; Rietjens, Judith; van der Heide, Agnes; Milota, Megan; van Delden, Johannes; Kars, Marijke (Wiley-Blackwell, 2021-01)

AIM: This study described the development, and pilot evaluation, of the Implementing Pediatric Advance Care Planning Toolkit (IMPACT). METHODS: Key elements of paediatric advance care planning (ACP) were defined using a ...
Intracranial Recordings Reveal Unique Shape and Timing of Responses in Human Visual Cortex during Illusory Visual Events

de Jong, Maartje C; Vansteensel, Mariska J; van Ee, Raymond; Leijten, Frans S S; Ramsey, Nick F; Dijkerman, H Chris; Dumoulin, Serge O; Knapen, Tomas (Cell Press, 2020-08-17)

de Jong et al. find that the processing hierarchy of perceptual changes during binocular rivalry is reversed compared to processing of stimulus changes. Binocular rivalry responses in ventral regions precede those in early ...
Long-term renal disease after prematurity or fetal growth restriction: who is at risk?

Terstappen, Fieke; Lely, A Titia (Oxford University Press, 2020-07)
Paradox of HIV stigma in an integrated chronic disease care in rural South Africa: Viewpoints of service users and providers

Ameh, Soter; D'Ambruoso, Lucia; Gómez-Olivé, Francesc Xavier; Kahn, Kathleen; Tollman, Stephen M; Klipstein-Grobusch, Kerstin (Public Library of Science, 2020-07-31)

BACKGROUND: An integrated chronic disease management (ICDM) model was introduced by the National Department of Health in South Africa to tackle the dual burden of HIV/AIDS and non-communicable diseases. One of the aims of ...
Desmin is essential for the structure and function of the sinoatrial node; implications for increased arrhythmogenesis

Mavroidis, Manolis; Athanasiadis, Nikolaos C; Rigas, Pavlos Stavros; Kostavasili, Ioanna; Kloukina, Ismini; Te Rijdt, Wouter P; Kavantzas, Nikolaos; Chaniotis, Dimitris; van Tintelen, J Peter; Skaliora, Irini; Davos, Constantinos H (American Physiological Society, 2020-09-01)

Our objective was to investigate the effect of desmin depletion on the structure and function of the sinoatrial pacemaker complex (SANcl) and its implication in arrhythmogenesis. Analysis of mice and humans (SANcl) indicated ...
The phospholamban p.(Arg14del) pathogenic variant leads to cardiomyopathy with heart failure and is unreponsive to standard heart failure therapy

Eijgenraam, Tim R; Boukens, Bastiaan J; Boogerd, Cornelis J; Schouten, E Marloes; van de Kolk, Cees W A; Stege, Nienke M; Te Rijdt, Wouter P; Hoorntje, Edgar T; van der Zwaag, Paul A; van Rooij, Eva; van Tintelen, Peter; van den Berg, Maarten P; van der Meer, Peter; van der Velden, Jolanda; Silljé, Herman H W; de Boer, Rudolf A (Nature Publishing Group, 2020-12-01)

Phospholamban (PLN) plays a role in cardiomyocyte calcium handling as primary inhibitor of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA). The p.(Arg14del) pathogenic variant in the PLN gene results in a high risk of ...
Untangling the diffusion signal using the phasor transform

van Rijssel, Michael J.; Froeling, Martijn; van Lier, Astrid L.H.M.W.; Verhoeff, Joost J.C.; Pluim, Josien P.W. (John Wiley & Sons Inc., 2020-12-01)

Separating the decay signal from diffusion-weighted scans into two or more components can be challenging. The phasor technique is well established in the field of optical microscopy for visualization and separation of ...
Noninvasive optical detection of granzyme B from natural killer cells with enzyme-activated fluorogenic probes

Janiszewski, Tomasz; Kołt, Sonia; Kaiserman, Dion; Snipas, Scott J.; Li, Shuang; Kulbacka, Julita; Saczko, Jolanta; Bovenschen, Niels; Salvesen, Guy; Drąg, Marcin; Bird, Phillip I.; Kasperkiewicz, Paulina (American Society for Biochemistry and Molecular Biology Inc., 2020-07-10)

Natural killer (NK) cells are key innate immunity effectors that combat viral infections and control several cancer types. For their immune function, human NK cells rely largely on five different cytotoxic proteases, called ...
A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

Venø, Morten T.; Reschke, Cristina R.; Morris, Gareth; Connolly, Niamh M.C.; Su, Junyi; Yan, Yan; Engel, Tobias; Jimenez-Mateos, Eva M.; Harder, Lea M.; Pultz, Dennis; Haunsberger, Stefan J.; Pal, Ajay; Heller, Janosch P.; Campbell, Aoife; Langa, Elena; Brennan, Gary P.; Conboy, Karen; Richardson, Amy; Norwood, Braxton A.; Costard, Lara S.; Neubert, Valentin; Gallo, Federico Del; Salvetti, Beatrice; Vangoor, Vamshidhar R.; Sanz-Rodriguez, Amaya; Muilu, Juha; Fabene, Paolo F.; Pasterkamp, R. Jeroen; Prehn, Jochen H.M.; Schorge, Stephanie; Andersen, Jens S.; Rosenow, Felix; Bauer, Sebastian; Kjems, Jørgen; Henshall, David C. (National Academy of Sciences, 2020-07-07)

Temporal lobe epilepsy is the most common drug-resistant form of epilepsy in adults. The reorganization of neural networks and the gene expression landscape underlying pathophysiologic network behavior in brain structures ...
Klinische epidemiologie: maximale detrusorcontractiekracht gerelateerd aan leeftijd en geslacht

Rosier, Peter F.W.M.; ten Donkelaar, Celine S.; de Kort, Laetitia M.O. (Springer Science + Business Media, 2020-07-01)

To report clinical epidemiology of detrusor (bladder) muscle contraction maximum related to ageing in patients referred with signs and symptoms of lower urinary tract dysfunction. One thousand three hundred and eight ...
Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response

van der Kooij, Monique K; Wetzels, Marjolein J A L; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Boers-Sonderen, Marye J; Dierselhuis, Miranda P; de Groot, Jan Willem B; Hospers, Geke A P; Piersma, Djura; van Rijn, Rozemarijn S; Suijkerbuijk, Karijn P M; Ten Tije, Albert J; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Wouters, Michel W J M; Haanen, John B A G; van den Eertwegh, Alfonsus J M; Bastiaannet, Esther; Kapiteijn, Ellen (Multidisciplinary Digital Publishing Institute (MDPI), 2020-08)

Cutaneous melanoma is a common type of cancer in Adolescents and Young Adults (AYAs, 15-39 years of age). However, AYAs are underrepresented in clinical trials investigating new therapies and the outcomes from these therapies ...
Virtual monochromatic dual-energy CT reconstructions improve detection of cerebral infarct in patients with suspicion of stroke

van Ommen, Fasco; Dankbaar, Jan Willem; Zhu, Guangming; Wolman, Dylan N.; Heit, Jeremy J; Kauw, Frans; Bennink, E; de Jong, Hugo; Wintermark, Max (Springer-Verlag, 2021-01)

Purpose: Early infarcts are hard to diagnose on non-contrast head CT. Dual-energy CT (DECT) may potentially increase infarct differentiation. The optimal DECT settings for differentiation were identified and evaluated. ...
Cost-benefit of outcome adjudication in nine randomised stroke trials

Godolphin, Peter J; Bath, Philip M; Algra, Ale; Berge, Eivind; Chalmers, John; Eliasziw, Misha; Hankey, Graeme J; Hosomi, Naohisa; Ranta, Annamarei; Weimar, Christian; Woodhouse, Lisa J; Montgomery, Alan A (SAGE Publications Ltd, 2020-10)

BACKGROUND: Central adjudication of outcomes is common for randomised trials and should control for differential misclassification. However, few studies have estimated the cost of the adjudication process. METHODS: We ...

Now showing items 18941-18960 of 40729