Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

  • Preferential differences in vaccination decision-making for oneself or one's child in The Netherlands: a discrete choice experiment 
    Hoogink, Joram; Verelst, Frederik; Kessels, Roselinde; van Hoek, Albert Jan; Timen, Aura; Willem, Lander; Beutels, Philippe; Wallinga, Jacco; de Wit, G Ardine (BioMed Central, 2020-06-01)
    BACKGROUND: To optimize the focus of future public information campaigns in The Netherlands promoting the uptake of vaccines among adults and children, we quantified the contribution of several attributes to the vaccination ...
  • Cost-effectiveness of mandatory bicycle helmet use to prevent traumatic brain injuries and death 
    Reuvers, Rick; Over, Eelco A B; Suijkerbuijk, Anita W M; Polder, Johan J; de Wit, G Ardine; van Gils, Paul F (BioMed Central, 2020-03-30)
    BACKGROUND: Traumatic brain injury (TBI) is the main cause of mortality and severe morbidity in cyclists admitted to Dutch emergency departments (EDs). Although the use of bicycle helmets is an effective way of preventing ...
  • Key questions for modelling COVID-19 exit strategies: COVID-19 Exit Strategies 
    Thompson, Robin N; Hollingsworth, T Déirdre; Isham, Valerie; Arribas-Bel, Daniel; Ashby, Ben; Britton, Tom; Challenor, Peter; Chappell, Lauren H K; Clapham, Hannah; Cunniffe, Nik J; Dawid, A Philip; Donnelly, Christl A; Eggo, Rosalind M; Funk, Sebastian; Gilbert, Nigel; Glendinning, Paul; Gog, Julia R; Hart, William S; Heesterbeek, Hans; House, Thomas; Keeling, Matt; Kiss, István Z; Kretzschmar, Mirjam E; Lloyd, Alun L; McBryde, Emma S; McCaw, James M; McKinley, Trevelyan J; Miller, Joel C; Morris, Martina; O'Neill, Philip D; Parag, Kris V; Pearson, Carl A B; Pellis, Lorenzo; Pulliam, Juliet R C; Ross, Joshua V; Tomba, Gianpaolo Scalia; Silverman, Bernard W; Struchiner, Claudio J; Tildesley, Michael J; Trapman, Pieter; Webb, Cerian R; Mollison, Denis; Restif, Olivier (Royal Society Publishing, 2020-08-12)
    Combinations of intense non-pharmaceutical interventions (lockdowns) were introduced worldwide to reduce SARS-CoV-2 transmission. Many governments have begun to implement exit strategies that relax restrictions while ...
  • Clustering of chronic hepatitis B screening intentions in social networks of Moroccan immigrants in the Netherlands 
    Hamdiui, Nora; Buskens, Vincent; Van Steenbergen, Jim E.; Kretzschmar, Mirjam E.E.; Rocha, Luis E.C.; Thorson, Anna E.; Timen, Aura; Wong, Albert; Van Den Muijsenbergh, Maria; Stein, Mart L. (BioMed Central, 2020-03-17)
    Background: Early detection, identification, and treatment of chronic hepatitis B through screening is vital for those at increased risk, e.g. born in hepatitis B endemic countries. In the Netherlands, Moroccan immigrants ...
  • Hepatitis B prevention: Can we learn from the response to HIV/AIDS? 
    Kretzschmar, Mirjam E.E.; van der Sande, Marianne A.B. (Public Library of Science, 2020-04-21)
    Mirjam Kretzschmar and Marianne van der Sande discuss the accompanying research study by Anna McNaughton and colleagues on strategies to reduce the burden of hepatitis B in African countries.
  • Relationship between Coxiella burnetii (Q fever) antibody serology and time spent outdoors 
    Klous, Gijs; Smit, Lidwien AM; van der Hoek, Wim; Kretzschmar, Mirjam EE; Vellema, Piet; Coutinho, Roel A.; Heederik, Dick JJ; Huss, Anke (W.B. Saunders Ltd, 2020-07)
    Background/aim: From 2007 through 2010, the Netherlands experienced the largest recorded Q fever outbreak to date. People living closer to Coxiella burnetii infected goat farms were at increased risk for acute Q fever. ...
  • Short- and long-term impact of vaccination against cytomegalovirus: a modeling study 
    Rozhnova, Ganna; Kretzschmar, Mirjam E.; Van Der Klis, Fiona; Van Baarle, Debbie; Korndewal, Marjolein; C. Vossen, Ann; Van Boven, Michiel (BioMed Central Ltd., 2020-07-02)
    Background: Infection with cytomegalovirus (CMV) is highly prevalent worldwide and can cause severe disease in immunocompromised persons and congenitally infected infants. The disease burden caused by congenital CMV infection ...
  • The impact of STI test results and face-to-face consultations on subsequent behavior and psychological characteristics 
    van Wees, Daphne A.; Drissen, Meggie M.C.M.; den Daas, Chantal; Heijman, Titia; Kretzschmar, Mirjam E.E.; Heijne, Janneke C.M. (Academic Press Inc., 2020-10)
    Sexually transmitted infection (STI) testing without face-to-face counselling is increasingly offered at sexual health centers (SHC), and ordering self-sampling tests online is becoming more popular. However, the impact ...
  • Impact of self-imposed prevention measures and short-term government-imposed social distancing on mitigating and delaying a COVID-19 epidemic: a modelling study 
    Teslya, Alexandra; Pham, Thi Mui; Godijk, Noortje G.; Kretzschmar, Mirjam E.; Bootsma, Martin C.J.; Rozhnova, Ganna (Public Library of Science, 2020-07-01)
    BACKGROUND: The coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every country in the world since it first emerged in China in December 2019. ...
  • Point-of-Care Analysis of Neutrophil Phenotypes: A First Step Toward Immuno-Based Precision Medicine in the Trauma ICU 
    Spijkerman, Roy; Hesselink, Lillian; Bongers, Suzanne; van Wessem, Karlijn J P; Vrisekoop, Nienke; Hietbrink, Falco; Koenderman, Leo; Leenen, Luke P H (Lippincott Williams & Wilkins, 2020-07-17)
    Objectives: The amount of tissue damage and the amplitude of the immune response after trauma are related to the development of infectious complications later on. Changes in the neutrophil compartment can be used as read ...
  • Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients 
    Dominantly Inherited Alzheimer Network (DIAN)* DELCODE study group* Alzheimer's Disease Neuroimaging Initiative (ADNI)* Utrecht VCI study group* (John Wiley & Sons Inc., 2020-11)
    INTRODUCTION: Microstructural alterations as assessed by diffusion tensor imaging (DTI) are key findings in both Alzheimer's disease (AD) and small vessel disease (SVD). We determined the contribution of each of these ...
  • Detection of breast cancer precursor lesions by autofluorescence ductoscopy 
    Waaijer, Laurien; Filipe, Mando D.; Simons, Janine; van der Pol, Carmen C.; de Boorder, Tjeerd; van Diest, Paul J.; Witkamp, Arjen Joost (Springer Japan, 2021-01)
    Purpose: Autofluorescence is an image enhancement technique used for the detection of cancer precursor lesions in pulmonary and gastrointestinal endoscopy. This study evaluated the feasibility of addition of autofluorescence ...
  • Conditionally essential genes for survival during starvation in Enterococcus faecium E745 
    de Maat, Vincent; Arredondo-Alonso, Sergio; Willems, Rob J.L.; van Schaik, Willem (BioMed Central, 2020-08-18)
    BACKGROUND: The nosocomial pathogen Enterococcus faecium can survive for prolonged periods of time on surfaces in the absence of nutrients. This trait is thought to contribute to the ability of E. faecium to spread among ...
  • The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia 
    Kalsbeek, Martin Jt; Wolff, Samantha Ec; Korpel, Nikita L.; la Fleur, Susanne E.; Romijn, Johannes A.; Fliers, Eric; Kalsbeek, Andries; Swaab, Dick F.; Huitinga, Inge; Hol, Elly M.; Yi, Chun Xia (American Society for Clinical Investigation, 2020-08-20)
    Animal studies indicate that hypothalamic dysfunction plays a major role in type 2 diabetes mellitus (T2DM) development, and that insulin resistance and inflammation are important mechanisms involved in this disorder. ...
  • A field strength independent MR radiomics model to predict pathological complete response in locally advanced rectal cancer 
    Cusumano, Davide; Meijer, Gert; Lenkowicz, Jacopo; Chiloiro, Giuditta; Boldrini, Luca; Masciocchi, Carlotta; Dinapoli, Nicola; Gatta, Roberto; Casà, Calogero; Damiani, Andrea; Barbaro, Brunella; Gambacorta, Maria Antonietta; Azario, Luigi; De Spirito, Marco; Intven, Martijn; Valentini, Vincenzo (Springer Verlag Italia, 2021-03)
    PURPOSE: Aim of this study was to develop a generalised radiomics model for predicting pathological complete response after neoadjuvant chemo-radiotherapy in locally advanced rectal cancer patients using pre-CRT T2-weighted ...
  • Impact on postoperative complications of changes in skeletal muscle mass during neoadjuvant chemotherapy for gastro-oesophageal cancer 
    den Boer, R B; Jones, K I; Ash, S; van Boxel, G I; Gillies, R S; O'Donnell, T; Ruurda, J P; Sgromo, B; Silva, M A; Maynard, N D (John Wiley & Sons Inc., 2020-10)
    BACKGROUND: Risk assessment is relevant to predict postoperative outcomes in patients with gastro-oesophageal cancer. This cohort study aimed to assess body composition changes during neoadjuvant chemotherapy and investigate ...
  • Velocity Pulsatility and Arterial Distensibility Along the Internal Carotid Artery 
    van Tuijl, Rick J.; Ruigrok, Ynte M.; Velthuis, Birgitta K.; van der Schaaf, Irene C.; Rinkel, Gabriël J.E.; Zwanenburg, Jaco J.M. (Wiley-Blackwell, 2020-08-18)
    Background Attenuation of velocity pulsatility along the internal carotid artery (ICA) is deemed necessary to protect the microvasculature of the brain. The role of the carotid siphon within the whole ICA trajectory in ...
  • Real-world Outcomes of First-line Anti-PD-1 Therapy for Advanced Melanoma: A Nationwide Population-based Study 
    van Zeijl, Michiel C T; Haanen, John B A G; Wouters, Michel W J M; de Wreede, Liesbeth C; Jochems, Anouk; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; de Groot, Jan Willem B; Hospers, Geke A P; Kapiteijn, Ellen W; Piersma, Djura; van Rijn, Rozemarijn S; Suijkerbuijk, Karijn P M; Ten Tije, Albert J; van der Veldt, Astrid A M; Vreugdenhil, Gerard; van der Hoeven, Koos J M; van den Eertwegh, Alfons J M (Landes Bioscience, 2020-10)
    The efficacy of anti-programmed death-1 (PD-1) monotherapy for advanced melanoma has been established, but it is unknown to what extent patients benefit in the real world. In this observational study with nationwide ...
  • Survival outcomes of patients with advanced mucosal melanoma diagnosed from 2013 to 2017 in the Netherlands – A nationwide population-based study 
    van Zeijl, Michiel C.T.; Boer, Florine L.; van Poelgeest, Mariëtte I.E.; van den Eertwegh, Alfons J.M.; Wouters, Michel W.J.M.; de Wreede, Liesbeth C.; Aarts, Maureen J.B.; van den Berkmortel, Franchette W.P.J.; de Groot, Jan Willem B.; Hospers, Geke A.P.; Piersma, Djura; van Rijn, Rozemarijn S.; Suijkerbuijk, Karijn P.M.; ten Tije, Albert J.; van der Veldt, Astrid A.M.; Vreugdenhil, Gerard; Boers-Sonderen, Marye J.; Kapiteijn, Ellen H.W.; Haanen, John B.A.G. (Elsevier Limited, 2020-09)
    Background: Mucosal melanoma (MM) is rare and has a poor prognosis. Since 2011, new effective treatments are available for advanced melanoma. It is unclear whether patients with mucosal melanoma equally benefit from these ...
  • Strength of patient cohorts and biobanks for cardiomyopathy research 
    DOSIS consortium (Bohn Stafleu van Loghum, 2020-08-01)
    In 2011 the Netherlands Heart Foundation allocated funding (CVON, Cardiovasculair Onderzoek Nederland) to stimulate collaboration between clinical and preclinical researchers on specific areas of research. One of those ...