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Now showing items 18181-18200 of 40729

Comparing psychotic experiences in low-and-middle-income-countries and high-income-countries with a focus on measurement invariance

Jaya, Edo S; Wüsten, Caroline; Alizadeh, Behrooz Z; van Amelsvoort, Therese; Bartels-Velthuis, Agna A; van Beveren, Nico J; Bruggeman, Richard; Cahn, Wiepke; de Haan, Lieuwe; Delespaul, Philippe; Luykx, Jurjen J; Myin-Germeys, Inez; Kahn, Rene S; Schirmbeck, Frederike; Simons, Claudia J P; van Haren, Neeltje E; van Os, Jim; van Winkel, Ruud; Fonseca-Pedrero, Eduardo; Peters, Emmanuelle; Verdoux, Hélène; Woodward, Todd S; Ziermans, Tim B; Lincoln, Tania M (Cambridge University Press, 2022-06)

Abstract Background The prevalence of psychotic experiences (PEs) is higher in low-and-middle-income-countries (LAMIC) than in high-income countries (HIC). Here, we examine whether this effect is explicable by measurement ...
Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands (GJB, GJER) (Wiley-Liss Inc., 2022-01)

First-degree relatives of patients diagnosed with schizophrenia (SZ-FDRs) show similar patterns of brain abnormalities and cognitive alterations to patients, albeit with smaller effect sizes. First-degree relatives of ...
Mutations and mechanisms of WNT pathway tumour suppressors in cancer

Bugter, Jeroen M; Fenderico, Nicola; Maurice, Madelon M (Nature Publishing Group, 2021-01)

Mutation-induced activation of WNT-β-catenin signalling is a frequent driver event in human cancer. Sustained WNT-β-catenin pathway activation endows cancer cells with sustained self-renewing growth properties and is ...
The YOUth study: Rationale, design, and study procedures

Onland-Moret, N. Charlotte; Buizer-Voskamp, Jacobine E.; Albers, Maria E.W.A.; Brouwer, Rachel M.; Buimer, Elizabeth E.L.; Hessels, Roy S.; de Heus, Roel; Huijding, Jorg; Junge, Caroline M.M.; Mandl, René C.W.; Pas, Pascal; Vink, Matthijs; van der Wal, Juliëtte J.M.; Hulshoff Pol, Hilleke E.; Kemner, Chantal (Elsevier, 2020-12)

Behavioral development in children shows large inter-individual variation, and is driven by the interplay between biological, psychological, and environmental processes. However, there is still little insight into how these ...
Demographic and health-related factors associated with reduced work functioning in people with moderate medically unexplained physical symptoms: a cross-sectional study

van Tilburg, Mark L; van Westrienen, Paula Elisabeth; Pisters, Martijn F (BioMed Central, 2020-08-31)

Background: Medically unexplained physical symptoms (MUPS) are a leading cause of reduced work functioning. It is not known which factors are associated with reduced work functioning in people with moderate MUPS. Insight ...
Movement behaviour patterns in patients with hip and/or knee osteoarthritis in the physical therapy setting: a cross-sectional study

de Hoop, Anne Maria Sjoerdtje; Kloek, Corelien Jacoba Johanna; Pisters, Martijn Frits; Veenhof, Cindy (BioMed Central, 2020-10-06)

BACKGROUND: Osteoarthritis is one of the most common chronic joint diseases, mostly affecting the knee or hip through pain, joint stiffness and decreased physical functioning in daily life. Regular physical activity (PA) ...
Measuring exercise adherence in patients with low back pain: development, validity, and reliability of the EXercise Adherence Scale (EXAS)

Arensman, Remco M; Geelen, Rianne H; Koppenaal, Tjarco; Veenhof, Cindy; Pisters, Martijn F (Informa Healthcare, 2022-07-03)

OBJECTIVES: To develop an instrument to measure adherence to frequency, intensity, and quality of performance of home-based exercise (HBE) programs recommended by a physical therapist and to evaluate its construct validity ...
Black-Blood Contrast in Cardiovascular MRI

Henningsson, Markus; Malik, Shaihan; Botnar, Rene; Castellanos, Daniel; Hussain, Tarique; Leiner, Tim (John Wiley & Sons Inc., 2022-01)

MRI is a versatile technique that offers many different options for tissue contrast, including suppressing the blood signal, so-called black-blood contrast. This contrast mechanism is extremely useful to visualize the ...
The effect of etidronate on choroidal neovascular activity in patients with pseudoxanthoma elasticum

Risseeuw, Sara; van Leeuwen, Redmer; Imhof, Saskia M; de Jong, Pim A; Mali, Willem P Th M; Spiering, Wilko; Ossewaarde-van Norel, Jeannette (Public Library of Science, 2020-10)

AIM: To assess the effect of the bisphosphonate etidronate on choroidal neovascular (CNV) activity in patients with pseudoxanthoma elasticum (PXE). METHODS: This is an ancillary study in a single center, randomized, ...
Volumetric breast density estimation on MRI using explainable deep learning regression

van der Velden, Bas H M; Janse, Markus H A; Ragusi, Max A A; Loo, Claudette E; Gilhuijs, Kenneth G A (Nature Publishing Group, 2020-10-22)

To purpose of this paper was to assess the feasibility of volumetric breast density estimations on MRI without segmentations accompanied with an explainability step. A total of 615 patients with breast cancer were included ...
Optimal 68Ga-PSMA and 18F-PSMA PET window levelling for gross tumour volume delineation in primary prostate cancer

Draulans, Cédric; De Roover, Robin; van der Heide, Uulke A; Kerkmeijer, Linda; Smeenk, Robert J; Pos, Floris; Vogel, Wouter V; Nagarajah, James; Janssen, Marcel; Isebaert, Sofie; Maes, Frederik; Mai, Cindy; Oyen, Raymond; Joniau, Steven; Kunze-Busch, Martina; Goffin, Karolien; Haustermans, Karin (Springer-Verlag, 2021-04)

Purpose: This study proposes optimal tracer-specific threshold-based window levels for PSMA PET–based intraprostatic gross tumour volume (GTV) contouring to reduce interobserver delineation variability. Methods: Nine ...
Primary endpoint analysis of the multicentre phase II hypo-FLAME trial for intermediate and high risk prostate cancer

Draulans, Cédric; van der Heide, Uulke A; Haustermans, Karin; Pos, Floris J; van der Voort van Zyp, Jochem; De Boer, Hans; Groen, Veerle H; Monninkhof, Evelyn M; Smeenk, Robert J; Kunze-Busch, Martina; De Roover, Robin; Depuydt, Tom; Isebaert, Sofie; Kerkmeijer, Linda G W (Elsevier Ireland Ltd, 2020-06)

BACKGROUND AND PURPOSE: Local recurrences after radiotherapy for prostate cancer (PCa) often originate at the location of the macroscopic tumour(s). Since PCa cells are known to be sensitive to high fraction doses, ...
Knowledge-Based Assessment of Focal Dose Escalation Treatment Plans in Prostate Cancer

van Schie, Marcel A; Janssen, Tomas M; Eekhout, Dave; Walraven, Iris; Pos, Floris J; de Ruiter, Peter; Kotte, Alexis N T J; Monninkhof, Evelyn M; Kerkmeijer, Linda G W; Draulans, Cédric; de Roover, Robin; Haustermans, Karin; Kunze-Busch, Martina; Smeenk, Robert Jan; van der Heide, Uulke A (Elsevier, 2020-11-15)

PURPOSE: In a randomized focal dose escalation radiation therapy trial for prostate cancer (FLAME), up to 95 Gy was prescribed to the tumor in the dose-escalated arm, with 77 Gy to the entire prostate in both arms. As dose ...
ADC measurements on the Unity MR-linac - A recommendation on behalf of the Elekta Unity MR-linac consortium

Kooreman, Ernst S; van Houdt, Petra J; Keesman, Rick; Pos, Floris J; van Pelt, Vivian W J; Nowee, Marlies E; Wetscherek, Andreas; Tijssen, Rob H N; Philippens, Marielle E P; Thorwarth, Daniela; Wang, Jihong; Shukla-Dave, Amita; Hall, William A; Paulson, Eric S; van der Heide, Uulke A (Elsevier Ireland Ltd, 2020-12)

BACKGROUND AND PURPOSE: Diffusion-weighted imaging (DWI) for treatment response monitoring is feasible on hybrid magnetic resonance linear accelerator (MR-linac) systems. The MRI scanner of the Elekta Unity system has an ...
31P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations

Experts' Working Group on 31P MR Spectroscopy of Skeletal Muscle (John Wiley & Sons Inc., 2021-05)

Skeletal muscle phosphorus-31 31 P MRS is the oldest MRS methodology to be applied to in vivo metabolic research. The technical requirements of 31 P MRS in skeletal muscle depend on the research question, and to assess ...
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging

de Bruijn, Henriette S; Mashayekhi, Vida; Schreurs, Tom J L; van Driel, Pieter B A A; Strijkers, Gustav J; van Diest, Paul J; Lowik, Clemens W G M; Seynhaeve, Ann L B; Hagen, Timo L M Ten; Prompers, Jeanine J; Henegouwen, Paul M P van Bergen En; Robinson, Dominic J; Oliveira, Sabrina (Ivyspring International Publisher, 2020)

Targeted photodynamic therapy (PDT) has the potential to selectively damage tumor tissue and to increase tumor vessel permeability. Here we characterize the tissue biodistribution of two EGFR-targeted nanobody-photosensitizer ...
New Developments in Imaging for Sentinel Lymph Node Biopsy in Early-Stage Oral Cavity Squamous Cell Carcinoma

Mahieu, Rutger; de Maar, Josanne S; Nieuwenhuis, Eliane R; Deckers, Roel; Moonen, Chrit; Alic, Lejla; Ten Haken, Bennie; de Keizer, Bart; Bree, Remco de (Multidisciplinary Digital Publishing Institute (MDPI), 2020-10-20)

Sentinel lymph node biopsy (SLNB) is a diagnostic staging procedure that aims to identify the first draining lymph node(s) from the primary tumor, the sentinel lymph nodes (SLN), as their histopathological status reflects ...
Revisiting B cell tolerance and autoantibodies in seropositive and seronegative autoimmune rheumatic disease (AIRD)

Pouw, J N Juliëtte; Leijten, E F A Emmerik; van Laar, J M Jacob; Boes, M Marianne (Wiley-Blackwell, 2021-02)

Autoimmune rheumatic diseases (AIRD) are categorized seropositive or seronegative, dependent upon the presence or absence of specific autoreactive antibodies, including rheumatoid factor and anti-citrullinated protein ...
Common Functional Ability Score for Young People With Juvenile Idiopathic Arthritis

Shoop-Worrall, Stephanie Jw; Oude Voshaar, Martijn Ah; McDonagh, Janet E; Van de Laar, Mart Afj; Wulffraat, Nico; Thomson, Wendy; Hyrich, Kimme L; Verstappen, Suzanne Mm (John Wiley & Sons Inc., 2021-07)

OBJECTIVE: As young people enter adulthood, the interchangeable use of child and adult outcome measures may inaccurately capture changes over time. This study aimed to use item response theory (IRT) to model a continuous ...
Tapering Canakinumab Monotherapy in Patients With Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results From a Phase IIIb/IV Open-Label, Randomized Study: Results From a Phase IIIb/IV Open-Label, Randomized Study

Pediatric Rheumatology International Trials Organization (PRINTO), the Pediatric Rheumatology Collaborative Study Group (PRCSG) (John Wiley & Sons Inc., 2021-02)

OBJECTIVE: To evaluate the efficacy and safety of 2 canakinumab monotherapy tapering regimens in order to maintain complete clinical remission in children with systemic juvenile idiopathic arthritis (JIA). METHODS: The ...

Now showing items 18181-18200 of 40729