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UMC Repository: Recent submissions

  • Sex differences in HIV treatment outcomes and adherence by exposure groups among adults in Guangdong, China: A retrospective observational cohort study 
    Li, Linghua; Yuan, Tanwei; Wang, Junfeng; Fitzpatrick, Thomas; Li, Quanming; Li, Peiyang; Tang, Xiaoping; Xu, Guohong; Chen, Dahui; Liang, Bowen; Cai, Weiping; Zou, Huachun (Elsevier, 2020-05)
    Introduction: We aimed to assess sex differences in treatment outcomes and adherence comparing men who have sex with women (MSW), men who have sex with men (MSM), and women who have sex with men (WSM), as well as men and ...
  • External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis 
    IPPIC Collaborative Network (BioMed Central Ltd., 2020-11-02)
    BACKGROUND: Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk during pregnancy is required to plan management. Although there are many published ...
  • IPDmada: An R Shiny tool for analyzing and visualizing individual patient data meta-analyses of diagnostic test accuracy 
    Wang, Junfeng; Keusters, Willem R; Wen, Lingzi; Leeflang, Mariska M G (John Wiley & Sons Inc., 2021-01)
    BACKGROUND: Individual patient data meta-analyses (IPD-MA) are regarded as the gold standard for systematic reviews, which also applies to systematic reviews of diagnostic test accuracy (DTA) studies. An increasing number ...
  • Intrinsic motivation of GPs was not related to recruitment success, whereas interest in the study topic was 
    Wang, Junfeng (Elsevier, 2020-09)
  • Hematopoietic cell transplantation in chronic granulomatous disease: a study of 712 children and adults 
    Chiesa, Robert; Wang, Junfeng; Blok, Henric-Jan; Hazelaar, Sheree; Neven, Benedicte; Moshous, Despina; Schulz, Ansgar; Hoenig, Manfred; Hauck, Fabian; Al Seraihy, Amal; Gozdzik, Jolanta; Ljungman, Per; Lindemans, Caroline A; Fernandes, Juliana F; Kalwak, Krzysztof; Strahm, Brigitte; Schanz, Urs; Sedlacek, Petr; Sykora, Karl-Walter; Aksoylar, Serap; Locatelli, Franco; Stepensky, Polina; Wynn, Robert; Lum, Su Han; Zecca, Marco; Porta, Fulvio; Taskinen, Mervi; Gibson, Brenda; Matthes, Susanne; Karakukcu, Musa; Hauri-Hohl, Mathias; Veys, Paul; Gennery, Andrew R; Lucchini, Giovanna; Felber, Matthias; Albert, Michael H; Balashov, Dmitry; Lankester, Arjan; Güngör, Tayfun; Slatter, Mary A (Elsevier, 2020-09-03)
    Chronic granulomatous disease (CGD) is a primary immunodeficiency resulting in life-threatening infections and inflammatory complications. Allogeneic hematopoietic cell transplantation (allo-HCT) can cure the disease, but ...
  • Thoracic imaging tests for the diagnosis of COVID-19 
    Salameh, Jean-Paul; Leeflang, Mariska Mg; Hooft, Lotty; Islam, Nayaar; McGrath, Trevor A; van der Pol, Christian B; Frank, Robert A; Prager, Ross; Hare, Samanjit S; Dennie, Carole; Spijker, René; Deeks, Jonathan J; Dinnes, Jacqueline; Jenniskens, Kevin; Korevaar, Daniël A; Cohen, Jérémie F; Van den Bruel, Ann; Takwoingi, Yemisi; van de Wijgert, Janneke; Damen, Johanna Aag; Wang, Junfeng; McInnes, Matthew Df; Cochrane COVID-19 Diagnostic Test Accuracy Group (John Wiley & Sons Inc., 2020-09-30)
    BACKGROUND: The diagnosis of infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents major challenges. Reverse transcriptase polymerase chain reaction (RT-PCR) testing is used to diagnose a ...
  • Use of biologicals in allergic and type-2 inflammatory diseases during the current COVID-19 pandemic: Position paper of Ärzteverband Deutscher Allergologen (AeDA)A, Deutsche Gesellschaft für Allergologie und Klinische Immunologie (DGAKI)B, Gesellschaft für Pädiatrische Allergologie und Umweltmedizin (GPA)C, Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI)D, Luxemburgische Gesellschaft für Allergologie und Immunologie (LGAI)E, Österreichische Gesellschaft für Pneumologie (ÖGP)F in co-operation with the German, Austrian, and Swiss ARIA groupsG, and the European Academy of Allergy and Clinical Immunology (EAACI)H 
    Klimek, Ludger; Pfaar, Oliver; Worm, Margitta; Eiwegger, Thomas; Hagemann, Jan; Ollert, Markus; Untersmayr, Eva; Hoffmann-Sommergruber, Karin; Vultaggio, Alessandra; Agache, Ioana; Bavbek, Sevim; Bossios, Apostolos; Casper, Ingrid; Chan, Susan; Chatzipetrou, Alexia; Vogelberg, Christian; Firinu, Davide; Kauppi, Paula; Kolios, Antonios; Kothari, Akash; Matucci, Andrea; Palomares, Oscar; Szépfalusi, Zsolt; Pohl, Wolfgang; Hötzenecker, Wolfram; Rosenkranz, Alexander R; Bergmann, Karl-Christian; Bieber, Thomas; Buhl, Roland; Buters, Jeroen; Darsow, Ulf; Keil, Thomas; Kleine-Tebbe, Jörg; Lau, Susanne; Maurer, Marcus; Merk, Hans; Mösges, Ralph; Saloga, Joachim; Staubach, Petra; Jappe, Uta; Rabe, Klaus F; Rabe, Uta; Vogelmeier, Claus; Biedermann, Tilo; Jung, Kirsten; Schlenter, Wolfgang; Ring, Johannes; Chaker, Adam; Wehrmann, Wolfgang; Becker, Sven; Freudelsperger, Laura; Mülleneisen, Norbert; Nemat, Katja; Czech, Wolfgang; Wrede, Holger; Brehler, Randolf; Fuchs, Thomas; Tomazic, Peter-Valentin; Aberer, Werner; Fink-Wagner, Antje-Henriette; Horak, Fritz; Wöhrl, Stefan; Niederberger-Leppin, Verena; Pali-Schöll, Isabella; Pohl, Wolfgang; Roller-Wirnsberger, Regina; Spranger, Otto; Valenta, Rudolf; Akdis, Mübecell; Matricardi, Paolo M; Spertini, François; Khaltaev, Nicolai; Michel, Jean-Pierre; Nicod, Larent; Schmid-Grendelmeier, Peter; Idzko, Marco; Hamelmann, Eckard; Jakob, Thilo; Werfel, Thomas; Wagenmann, Martin; Taube, Christian; Jensen-Jarolim, Erika; Korn, Stephanie; Hentges, Francois; Schwarze, Jürgen; O Mahony, Liam; Knol, Edward F; Del Giacco, Stefano; Chivato Pérez, Tomás; Bousquet, Jean; Bedbrook, Anna; Zuberbier, Torsten; Akdis, Cezmi; Jutel, Marek (2020)
    BACKGROUND: Since the beginning of the COVID-19 pandemic, the treatment of patients with allergic and atopy-associated diseases has faced major challenges. Recommendations for "social distancing" and the fear of patients ...
  • Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids 
    Vonk, Annelotte M; van Mourik, Peter; Ramalho, Anabela S; Silva, Iris A L; Statia, Marvin; Kruisselbrink, Evelien; Suen, Sylvia W F; Dekkers, Johanna F; Vleggaar, Frank P; Houwen, Roderick H J; Mullenders, Jasper; Boj, Sylvia F; Vries, Robert; Amaral, Margarida D; de Boeck, Kris; van der Ent, Cornelis K; Beekman, Jeffrey M (Cell Press, 2020-06-19)
    This protocol describes the isolation, handling, culture of, and experiments with human colon stem cell organoids in the context of cystic fibrosis (CF). In human colon organoids, the function of cystic fibrosis transmembrane ...
  • Sex-specific outcome disparities in very old patients admitted to intensive care medicine: a propensity matched analysis 
    VIP2 study group (Nature Publishing Group, 2020-10-29)
    Female and male very elderly intensive patients (VIPs) might differ in characteristics and outcomes. We aimed to compare female versus male VIPs in a large, multinational collective of VIPs with regards to outcome and ...
  • Genetic Evaluation in a Cohort of 126 Dutch Pulmonary Arterial Hypertension Patients 
    van den Heuvel, Lieke M; Jansen, Samara M A; Alsters, Suzanne I M; Post, Marco C; van der Smagt, Jasper J; Handoko-De Man, Frances S; van Tintelen, J Peter; Gille, Hans; Christiaans, Imke; Vonk Noordegraaf, Anton; Bogaard, HarmJan; Houweling, Arjan C (Multidisciplinary Digital Publishing Institute (MDPI), 2020-10-13)
    Pulmonary arterial hypertension (PAH) is a severe, life-threatening disease, and in some cases is caused by genetic defects. This study sought to assess the diagnostic yield of genetic testing in a Dutch cohort of 126 PAH ...
  • Long-Term Follow-Up Study on the Uptake of Genetic Counseling and Predictive DNA Testing in Inherited Cardiac Conditions 
    van den Heuvel, Lieke M; van Teijlingen, Maxiem O; van der Roest, Wilma; van Langen, Irene M; Smets, Ellen M A; van Tintelen, J Peter; Christiaans, Imke (Lippincott Williams & Wilkins, 2020-10)
    BACKGROUND: Inherited cardiac conditions present with a wide range of symptoms and may even result in sudden cardiac death. Relatives of probands with a confirmed pathogenic genetic variant are advised predictive DNA testing ...
  • Early detection of small volume stroke and thromboembolic sources with computed tomography: Rationale and design of the ENCLOSE study 
    Kauw, Frans; van Ommen, Fasco; Bennink, Edwin; Cramer, Maarten J; Kappelle, L Jaap; Takx, Richard Ap; Velthuis, Birgitta K; Viergever, Max A; Wouter van Es, H; Schonewille, Wouter J; Coutinho, Jonathan M; Majoie, Charles Blm; Marquering, Henk A; de Jong, Hugo Wam; Dankbaar, Jan W (SAGE Publications Inc., 2020-12)
    Background: Computed tomography is the most frequently used imaging modality in acute stroke imaging protocols. Detection of small volume infarcts in the brain and cardioembolic sources of stroke is difficult with current ...
  • Symptom Remission and Brain Cortical Networks at First Clinical Presentation of Psychosis: The OPTiMiSE Study 
    OPTiMiSE study group (Oxford University Press, 2021-03-16)
    Individuals with psychoses have brain alterations, particularly in frontal and temporal cortices, that may be particularly prominent, already at illness onset, in those more likely to have poorer symptom remission following ...
  • Relationship between jumping to conclusions and clinical outcomes in people at clinical high-risk for psychosis 
    EU-GEI High Risk Study (Cambridge University Press, 2022-06)
    Background Psychosis is associated with a reasoning bias, which manifests as a tendency to 'jump to conclusions'. We examined this bias in people at clinical high-risk for psychosis (CHR) and investigated its relationship ...
  • A replication study of JTC bias, genetic liability for psychosis and delusional ideation 
    Henquet, Cécile; van Os, Jim; Pries, Lotta K; Rauschenberg, Christian; Delespaul, Philippe; Kenis, Gunter; Luykx, Jurjen J; Lin, Bochao D; Richards, Alexander L; Akdede, Berna; Binbay, Tolga; Altınyazar, Vesile; Yalınçetin, Berna; Gümüş-Akay, Güvem; Cihan, Burçin; Soygür, Haldun; Ulaş, Halis; Cankurtaran, Eylem S; Kaymak, Semra U; Mihaljevic, Marina M; Petrovic, Sanja S; Mirjanic, Tijana; Bernardo, Miguel; Mezquida, Gisela; Amoretti, Silvia; Bobes, Julio; Saiz, Pilar A; García-Portilla, Maria P; Sanjuan, Julio; Aguilar, Eduardo J; Santos, Jose L; Jiménez-López, Estela; Arrojo, Manuel; Carracedo, Angel; López, Gonzalo; González-Peñas, Javier; Parellada, Mara; Maric, Nadja P; Atbaşoğlu, Cem; Ucok, Alp; Alptekin, Köksal; Saka, Meram C; Arango, Celso; O'Donovan, Michael; Rutten, Bart P F; Gülöksüz, Sinan (Cambridge University Press, 2022-07)
    BACKGROUND: This study attempted to replicate whether a bias in probabilistic reasoning, or 'jumping to conclusions'(JTC) bias is associated with being a sibling of a patient with schizophrenia spectrum disorder; and if ...
  • Network approach of mood and functional gastrointestinal symptom dynamics in relation to childhood trauma in patients with irritable bowel syndrome and comorbid panic disorder 
    Drukker, Marjan; Peters, Jill C H; Vork, Lisa; Mujagic, Zlatan; Rutten, Bart P F; van Os, Jim; Masclee, Ad A M; Kruimel, Joanna W; Leue, Carsten (Elsevier, 2020-12)
    OBJECTIVE: Irritable bowel syndrome (IBS) has a high comorbidity with mental disorders. The present paper aims to visualise the interplay between IBS and affect (anxiety and mood) in daily life. Furthermore, this interplay ...
  • Early warning signals in psychopathology: what do they tell? 
    Schreuder, Marieke J; Hartman, Catharina A; George, Sandip V; Menne-Lothmann, Claudia; Decoster, Jeroen; van Winkel, Ruud; Delespaul, Philippe; De Hert, Marc; Derom, Catherine; Thiery, Evert; Rutten, Bart P F; Jacobs, Nele; van Os, Jim; Wigman, Johanna T W; Wichers, Marieke (BioMed Central Ltd., 2020-10-14)
    BACKGROUND: Despite the increasing understanding of factors that might underlie psychiatric disorders, prospectively detecting shifts from a healthy towards a symptomatic state has remained unattainable. A complex systems ...
  • Evidence, and replication thereof, that molecular-genetic and environmental risks for psychosis impact through an affective pathway 
    van Os, Jim; Pries, Lotta-Katrin; Ten Have, Margreet; de Graaf, Ron; van Dorsselaer, Saskia; Delespaul, Philippe; Bak, Maarten; Kenis, Gunter; Lin, Bochao D; Luykx, Jurjen J; Richards, Alexander L; Akdede, Berna; Binbay, Tolga; Altınyazar, Vesile; Yalınçetin, Berna; Gümüş-Akay, Güvem; Cihan, Burçin; Soygür, Haldun; Ulaş, Halis; Cankurtaran, Eylem Şahin; Kaymak, Semra Ulusoy; Mihaljevic, Marina M; Petrovic, Sanja Andric; Mirjanic, Tijana; Bernardo, Miguel; Mezquida, Gisela; Amoretti, Silvia; Bobes, Julio; Saiz, Pilar A; García-Portilla, María Paz; Sanjuan, Julio; Aguilar, Eduardo J; Santos, José Luis; Jiménez-López, Estela; Arrojo, Manuel; Carracedo, Angel; López, Gonzalo; González-Peñas, Javier; Parellada, Mara; Maric, Nadja P; Atbaşoğlu, Cem; Ucok, Alp; Alptekin, Köksal; Saka, Meram Can; Arango, Celso; O'Donovan, Michael; Rutten, Bart P F; Guloksuz, Sinan (Cambridge University Press, 2022-07-19)
    Background There is evidence that environmental and genetic risk factors for schizophrenia spectrum disorders are transdiagnostic and mediated in part through a generic pathway of affective dysregulation. Methods We analysed ...
  • Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis 
    EUGEI High-Risk Study (Springer Nature, 2021-06)
    Serum neuronal autoantibodies, such as those to the NMDA receptor (NMDAR), are detectable in a subgroup of patients with psychotic disorders. It is not known if they are present before the onset of psychosis or whether ...
  • Atypical Brain Asymmetry in Autism-A Candidate for Clinically Meaningful Stratification 
    EU-AIMS Longitudinal European Autism Project Group (Elsevier, 2021-08)
    BACKGROUND: Autism spectrum disorder ("autism") is a highly heterogeneous neurodevelopmental condition with few effective treatments for core and associated features. To make progress we need to both identify and validate ...