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Now showing items 16681-16700 of 40729

Shortening the paediatric Haemophilia Activities List (pedHAL) based on pooled data from international studies

Kuijlaars, Isolde A.R.; van der Net, Janjaap; Bouskill, Vanessa; Hilliard, Pamela; Juodyte, Agne; Khair, Kate; Trakymiene, Sonata Saulyte; Fischer, Kathelijn (Wiley-Blackwell, 2021-03)

Introduction: The paediatric Haemophilia Activities List (pedHAL) was developed to measure activities and participation in children and youth with haemophilia. Results from international studies provide an opportunity to ...
Development of entrustable professional activities for paediatric intensive care fellows: A national modified Delphi study

Hennus, Marije P; Nusmeier, Anneliese; van Heesch, Gwen G M; Riedijk, Maaike A; Schoenmaker, Nikki J; Soeteman, Marijn; Wildschut, Enno D; Fawns, Tim; Ten Cate, Olle (Public Library of Science, 2021-03-18)

Entrustable professional activities (EPAs), as a focus of learner assessment, are supported by validity evidence. An EPA is a unit of professional practice requiring proficiency in multiple competencies simultaneously, ...
Developing leadership in postdoctoral nurses: A longitudinal mixed-methods study

van Dongen, Lisa; Cardiff, Shaun; Kluijtmans, Manon; Schoonhoven, Lisette; Hamers, Jan P.H.; Schuurmans, Marieke J.; Hafsteinsdóttir, Thóra B. (Mosby Inc., 2021-07-01)

Background: Postdoctoral nurses have an important role in advancing nursing by generating knowledge and building networks in research, practice, and education which requires effective leadership. Therefore, the Leadership ...
New insights in phenotype and treatment of lung disease immuno-deficiency and chromosome breakage syndrome (LICS)

Willemse, Brigitte W M; van der Crabben, Saskia N; Kerstjens-Frederikse, Wilhelmina S; Timens, Wim; van Montfrans, Joris M; Lindemans, Caroline A; Boelens, Jaap Jan; Hennus, Marije P; van Haaften, Gijs (BioMed Central, 2021-03-19)

We report five patients with lung disease immuno-deficiency and chromosome breakage syndrome (LICS) but without recurrent infections and severe immunodeficiency. One patient had extended survival to 6.5 years. Hematopoietic ...
Sneller een ambulance bij thoracale klachten ’s nachts

Wouters, Loes; Zwart, Dorien; Erkelens, Carmen; Cheung, Noël; de Groot, Esther; Damoiseaux, Roger; Hoes, A. W.; Rutten, F. H. (Bohn Stafleu van Loghum, 2021-04)

’s Ochtends vroeg is de kans op een acuut coronair syndroom (ACS) het hoogst. Dat gegeven is bruikbaar voor telefonische triage op de huisartsenpost (HAP). Patiënten die tussen 00:00 en 09:00 uur de HAP bellen met acute ...
Clinical value of a screening tool for tumor predisposition syndromes in childhood cancer patients (TuPS): a prospective, observational, multi-center study

Postema, Floor A M; Hopman, Saskia M J; de Borgie, Corianne A J M; Aalfs, Cora M; Anninga, Jakob K; Berger, Lieke P V; Bleeker, Fonnet E; Dommering, Charlotte J; van Eijkelenburg, Natasha K A; Hammond, Peter; van den Heuvel-Eibrink, Marry M; Hol, Janna A; Kors, Wijnanda A; Letteboer, Tom G W; Loeffen, Jan L C M; Meijer, Lisethe; Olderode-Berends, Maran J W; Wagner, Anja; Hennekam, Raoul C; Merks, Johannes H M (Springer Netherlands, 2021-10)

Recognizing a tumor predisposition syndrome (TPS) in a child with cancer is of clinical relevance. Earlier we developed a screening tool to increase diagnostic accuracy and clinical efficiency of identifying TPSs in children ...
Changes in cartilage thickness and denuded bone area after knee joint distraction and high tibial osteotomy—post‐hoc analyses of two randomized controlled trials

Jansen, Mylène P.; Maschek, Susanne; van Heerwaarden, Ronald J.; Mastbergen, Simon C.; Wirth, Wolfgang; Lafeber, Floris P.J.G.; Eckstein, Felix (Multidisciplinary Digital Publishing Institute (MDPI), 2021-01-02)

High tibial osteotomy (HTO) and knee joint distraction (KJD) are joint‐preserving treat-ments that unload the more affected compartment (MAC) in knee osteoarthritis. This post‐hoc study compares two‐year cartilage‐thickness ...
Healthcare utilization and economic burden of difficult-to-treat rheumatoid arthritis: A cost-of-illness study

Roodenrijs, Nadia M.T.; Welsing, Paco M.J.; Van Der Goes, Marlies C.; Tekstra, Janneke; Lafeber, Floris P.J.G.; Jacobs, Johannes W.G.; Van Laar, Jacob M. (Oxford University Press, 2021-10-01)

Objectives: To determine the impact of difficult-to-treat rheumatoid arthritis (D2T RA) on (costs related to) healthcare utilization, other resource use and work productivity. Methods: Data regarding healthcare utilization, ...
Non-adherence in difficult-to-treat rheumatoid arthritis from the perspectives of patients and rheumatologists: a concept mapping study

Roodenrijs, Nadia M T; van der Goes, Marlies C; Welsing, Paco M J; van Oorschot, Eline P C; Nikiphorou, Elena; Nijhof, Nienke C; Tekstra, Janneke; Lafeber, Floris P J G; Jacobs, Johannes W G; van Laar, Jacob M; Geenen, Rinie (Oxford University Press, 2021-11-03)

OBJECTIVES: Treatment non-adherence is more frequent among difficult-to-treat (D2T) than among non-D2T RA patients. Perceptions of non-adherence may differ. We aimed to thematically structure and prioritize barriers to ...
Reply to: “six months vitamin K treatment does not affect systemic arterial calcification or bone mineral density in diabetes mellitus 2”

Bartstra, Jonas W.; de Jong, Pim A.; Beulens, Joline W.J. (Springer Science and Business Media Deutschland GmbH, 2021-04)
Culture and analysis of kidney tubuloids and perfused tubuloid cells-on-a-chip

Gijzen, Linda; Yousef Yengej, Fjodor A; Schutgens, Frans; Vormann, Marianne K; Ammerlaan, Carola M E; Nicolas, Arnaud; Kurek, Dorota; Vulto, Paul; Rookmaaker, Maarten B; Lanz, Henriette L; Verhaar, Marianne C; Clevers, Hans (Springer Nature, 2021-04)

Advanced in vitro kidney models are of great importance to the study of renal physiology and disease. Kidney tubuloids can be established from primary cells derived from adult kidney tissue or urine. Tubuloids are ...
Reply: Questionable recommendation for LPS for IVF/ICSI in ESHRE guideline 2019: ovarian stimulation for IVF/ICSI

Broekmans, Frank; Humaidan, Peter; Lainas, George; Töyli, Mira; Le Clef, Nathalie; Vermeulen, Nathalie (2021)
Pathophysiology of Cerebral Hyperperfusion in Term Neonates With Hypoxic-Ischemic Encephalopathy: A Systematic Review for Future Research

Kleuskens, Dianne G; Gonçalves Costa, Filipe; Annink, Kim V; van den Hoogen, Agnes; Alderliesten, Thomas; Groenendaal, Floris; Benders, Manon J N; Dudink, Jeroen (Frontiers Media S. A., 2021-02-02)

Worldwide neonatal hypoxic-ischemic encephalopathy (HIE) is a common cause of mortality and neurologic disability, despite the implementation of therapeutic hypothermia treatment. Advances toward new neuroprotective ...
Nu thuismeting van zuurstofsaturatie ineens reguliere huisartsenzorg lijkt te zijn…

Zwart, Dorien; Venekamp, Roderick; Smit, Karin; Geersing, Geert Jan; Kalkman, Cor; Rutten, Frans (Bohn Stafleu van Loghum, 2021-04)

Thuismeting van zuurstofsaturatie bij COVID-19-patiënten neemt momenteel een vlucht in de huisartsenpraktijk. Het is een praktisch middel om patiënten thuis te monitoren. De validiteit van de saturatiemetingen vormt echter ...
Correction: Significant Determinants of Mouse Pain Behaviour

Minett, Michael S; Eijkelkamp, Niels; Wood, John N (Public Library of Science, 2021-01)

There are a number of errors in the caption for Fig 3, “Comparison of different transgenic mice reveals stimulus-intensity specific responses to noxious thermal stimuli.” Please see the complete, correct Fig 3 caption here. ...
Experts' moral views on gene drive technologies: a qualitative interview study

de Graeff, N.; Jongsma, Karin R.; Bredenoord, Annelien L. (BioMed Central, 2021-03-08)

BACKGROUND: Gene drive technologies (GDTs) promote the rapid spread of a particular genetic element within a population of non-human organisms. Potential applications of GDTs include the control of insect vectors, invasive ...
Standard reference sequences for submission of HLA genotyping for the 18th International HLA and Immunogenetics Workshop

Matern, Benedict M; Mack, Steven J; Osoegawa, Kazutoyo; Maiers, Martin; Niemann, Matthias; Robinson, James; Heidt, Sebastiaan; Spierings, Eric (Wiley-Blackwell, 2021-06)

The International human leukocyte antigen (HLA) and Immunogenetics Workshops (IHIWs) have fostered international collaborations of researchers and experts in the fields of HLA, histocompatibility and immunology. These IHIW ...
Pharmacological validation of TDO as a target for Parkinson’s disease

Perez-Pardo, Paula; Grobben, Yvonne; Willemsen-Seegers, Nicole; Hartog, Mitch; Tutone, Michaela; Muller, Michelle; Adolfs, Youri; Pasterkamp, Ronald Jeroen; Vu-Pham, Diep; van Doornmalen, Antoon M.; van Cauter, Freek; de Wit, Joeri; Gerard Sterrenburg, Jan; Uitdehaag, Joost C.M.; de Man, Jos; Buijsman, Rogier C.; Zaman, Guido J.R.; Kraneveld, Aletta D. (Wiley-Blackwell, 2021-07)

Parkinson’s disease patients suffer from both motor and nonmotor impairments. There is currently no cure for Parkinson’s disease, and the most commonly used treatment, levodopa, only functions as a temporary relief of motor ...
Enrichment of Circular RNA Expression Deregulation at the Transition to Recurrent Spontaneous Seizures in Experimental Temporal Lobe Epilepsy

Gomes-Duarte, Andreia; Bauer, Sebastian; Venø, Morten T.; Norwood, Braxton A.; Henshall, David C.; Kjems, Jørgen; Rosenow, Felix; Vangoor, Vamshidhar R.; Pasterkamp, R. Jeroen (Frontiers Media S. A., 2021-01-28)

Mesial temporal lobe epilepsy (mTLE) is a common form of epilepsy and is characterized by recurrent spontaneous seizures originating from the temporal lobe. The majority of mTLE patients develop pharmacoresistance to ...
A population-based study on incidence, treatment, and survival in ampullary cancer in the Netherlands

Dutch Pancreatic Cancer Group (DPCG) (W.B. Saunders Ltd, 2021-07)

Introduction: Ampullary cancer is rare and as a result epidemiological data are scarce. The aim of this population-based study was to determine the trends in incidence, treatment and overall survival (OS) in patients with ...

Now showing items 16681-16700 of 40729