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Now showing items 16481-16500 of 40729

Genome-wide copy number variations as molecular diagnostic tool for cutaneous intermediate melanocytic lesions: a systematic review and individual patient data meta-analysis

Ebbelaar, Chiel F; Jansen, Anne M L; Bloem, Lourens T; Blokx, Willeke A M (Springer-Verlag, 2021-10)

Cutaneous intermediate melanocytic neoplasms with ambiguous histopathological features are diagnostically challenging. Ancillary cytogenetic techniques to detect genome-wide copy number variations (CNVs) might provide a ...
Diagnostic Strategies toward Clinical Implementation of Liquid Biopsy RAS/BRAF Circulating Tumor DNA Analyses in Patients with Metastatic Colorectal Cancer

van 't Erve, Iris; Greuter, Marjolein J E; Bolhuis, Karen; Vessies, Daan C L; Leal, Alessandro; Vink, Geraldine R; van den Broek, Daan; Velculescu, Victor E; Punt, Cornelis J A; Meijer, Gerrit A; Coupé, Veerle M H; Fijneman, Remond J A (Elsevier, 2020-12)

Detection of KRAS, NRAS, and BRAF mutations in tumor tissue is currently used to predict resistance to treatment with anti-epidermal growth factor receptor (EGFR) antibodies in patients with metastatic colorectal cancer ...
A standard set of outcome measures for the comprehensive assessment of osteogenesis imperfecta

Nijhuis, Wouter; Franken, Anton; Ayers, Kara; Damas, Chantal; Folkestad, Lars; Forlino, Antonella; Fraschini, Paolo; Hill, Claire; Janus, Guus; Kruse, Richard; Lande Wekre, Lena; Michiels, Lieve; Montpetit, Kathleen; Panzeri, Leonardo; Porquet-Bordes, Valerie; Rauch, Frank; Sakkers, Ralph; Salles, Jean Pierre; Semler, Oliver; Sun, Jony; To, Michael; Tosi, Laura; Yao, Yangyang; Yeung, Eric Hiu Kwong; Zhytnik, Lidiia; Zillikens, Maria Carola; Verhoef, Marjolein (BioMed Central, 2021-03-20)

Background: Osteogenesis Imperfecta (OI) is a genetic disorder also known as ‘brittle bone disease’. The clinical manifestation of OI shows a wide variation. Therefore, care for patients with OI requires an interdisciplinary ...
Model-based effectiveness and cost-effectiveness of risk-based selection strategies for adjuvant chemotherapy in Dutch stage II colon cancer patients

Jongeneel, Gabrielle; Greuter, Marjolein J E; van Erning, Felice N; Koopman, Miriam; Vink, Geraldine R; Punt, Cornelis J A; Coupé, Veerle M H (SAGE Publications Ltd, 2021-03)

Background: We aimed to evaluate the cost-effectiveness of risk-based strategies to improve the selection of surgically treated stage II colon cancer (CC) patients for adjuvant chemotherapy. Methods: Using the 'Personalized ...
Barriers to and solutions for improving physical activity in adults during hospital stay: a mixed-methods study among healthcare professionals

Geelen, Sven J G; Giele, Boukje M; Engelbert, Raoul H H; de Moree, Sandra; Veenhof, Cindy; Nollet, Frans; van Nes, Fenna; van der Schaaf, Marike (Informa Healthcare, 2022-07-17)

PURPOSE: To identify healthcare professionals' perspectives on key barriers to improving physical activity in hospitalized adult patients, and to identify solutions to overcome these barriers. Methods: We used an explanatory ...
Identifying goals, roles and tasks of extended scope physiotherapy in Dutch primary care- an exploratory, qualitative multi-step study

Bastiaens, Ferdinand; Barten, Di-Janne; Veenhof, Cindy (BioMed Central, 2021-01-06)

BACKGROUND: Rising healthcare costs, an increasing general practitioner shortage and an aging population have made healthcare organization transformation a priority. To meet these challenges, traditional roles of non-medical ...
Stratified care integrated with eHealth versus usual primary care physiotherapy in patients with neck and/or shoulder complaints: protocol for a cluster randomized controlled trial

van Tilburg, Mark L; Kloek, Corelien J J; Pisters, Martijn F; Staal, J Bart; van Dongen, Johanna M; de Weerd, Marjolein; Ostelo, Raymond W J G; Foster, Nadine E; Veenhof, Cindy (BioMed Central, 2021-02-05)

BACKGROUND: Neck and shoulder complaints are common in primary care physiotherapy. These patients experience pain and disability, resulting in high societal costs due to, for example, healthcare use and work absence. Content ...
The course of physical functioning in the first two years after stroke depends on peoples' individual movement behavior patterns

Wondergem, Roderick; Pisters, Martijn F; Wouters, Eveline Jm; de Bie, Rob A; Veenhof, Cindy; Visser-Meily, Johanna Ma (SAGE Publications Ltd, 2022-01-01)

BACKGROUND AND PURPOSE: Deterioration of physical functioning after stroke in the long term is regarded as a major problem. Currently, the relationship between "peoples'" movement behavior patterns (the composition of ...
The methodological quality of 176,620 randomized controlled trials published between 1966 and 2018 reveals a positive trend but also an urgent need for improvement

Vinkers, Christiaan H; Lamberink, Herm J; Tijdink, Joeri K; Heus, Pauline; Bouter, Lex; Glasziou, Paul; Moher, David; Damen, Johanna A; Hooft, Lotty; Otte, Willem M (Public Library of Science, 2021-04)

AU Many: Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly randomized controlled trials (RCTs) are biased and difficult : to reproduce due to methodological flaws and poor reporting. There is increasing attention ...
Glomerular Filtration Rate in Asphyxiated Neonates Under Therapeutic Whole-Body Hypothermia, Quantified by Mannitol Clearance

ALBINO Study Group (Adis, 2021-07)

BACKGROUND: Therapeutic hypothermia (TH) is an established intervention to improve the outcome of neonates with moderate-to-severe hypoxic-ischemic encephalopathy resulting from perinatal asphyxia. Despite this beneficial ...
The relationship between preterm birth and sleep in children at school age: A systematic review

Visser, Simone S M; van Diemen, Willemijn J M; Kervezee, Laura; van den Hoogen, Agnes; Verschuren, Olaf; Pillen, Sigrid; Benders, Manon J N L; Dudink, Jeroen (Elsevier, 2021-06)

Premature birth (before 37 weeks of gestation) has been linked to a variety of adverse neurological outcomes. Sleep problems are associated with decreased neurocognitive functioning, which is especially common in children ...
NutriBrain: protocol for a randomised, double-blind, controlled trial to evaluate the effects of a nutritional product on brain integrity in preterm infants

Hortensius, Lisa M; van den Hooven, Edith H; Dudink, Jeroen; Tataranno, Maria Luisa; van Elburg, Ruurd M; Benders, Manon J N L (BioMed Central, 2021-03-17)

Background: The gut microbiota and the brain are connected through different mechanisms. Bacterial colonisation of the gut plays a substantial role in normal brain development, providing opportunities for nutritional ...
The value of cardiorespiratory parameters for sleep state classification in preterm infants: A systematic review

de Groot, Eline R; Knoop, Marit S; van den Hoogen, Agnes; Wang, Xiaowan; Long, Xi; Pillen, Sigrid; Benders, Manon; Dudink, Jeroen (Elsevier, 2021-08)

Cardiorespiratory activity is highly associated with infants' sleep duration and quality. We performed a systematic literature search of PubMed and EMBASE databases to investigate if and how cardiorespiratory parameters ...
Cardiac hypertrophy at autopsy

Association for European Cardiovascular Pathology (Springer-Verlag, 2021-07)

Since cardiac hypertrophy may be considered a cause of death at autopsy, its assessment requires a uniform approach. Common terminology and methodology to measure the heart weight, size, and thickness as well as a systematic ...
False-negative programmed death-ligand 1 immunostaining in ethanol-fixed endobronchial ultrasound-guided transbronchial needle aspiration specimens of non-small-cell lung cancer patients

Koomen, Bregje M; Vreuls, Willem; de Boer, Mirthe; de Ruiter, Emma J; Hoelters, Juergen; Vink, Aryan; Willems, Stefan M (Wiley-Blackwell, 2021-10)

AIMS: Programmed death-ligand 1 (PD-L1) immunostaining is used to predict which non-small-cell lung cancer (NSCLC) patients will respond best to treatment with programmed cell death protein 1/PD-L1 inhibitors. PD-L1 ...
Dietary restriction in the long-chain acyl-CoA dehydrogenase knockout mouse

Diekman, Eugène F.; van Weeghel, Michel; Suárez-Fariñas, Mayte; Argmann, Carmen; Ranea-Robles, Pablo; Wanders, Ronald J.A.; Visser, Gepke; van der Made, Ingeborg; Creemers, Esther E.; Houten, Sander M. (Elsevier, 2021-06)

Patients with a disorder of mitochondrial long-chain fatty acid β-oxidation (FAO) have reduced fasting tolerance and may present with hypoketotic hypoglycemia, hepatomegaly, (cardio)myopathy and rhabdomyolysis. Patients ...
Robot-assisted Radical Cystectomy Versus Open Radical Cystectomy in Bladder Cancer Patients: A Multicentre Comparative Effectiveness Study

Wijburg, Carl J.; Michels, Charlotte T.J.; Hannink, Gerjon; Grutters, Janneke P.C.; Rovers, Maroeska M.; Alfred Witjes, J.; Witjes, J. Alfred; van Onna, Ilze E.W.; Barten, Evert J.; Koldewijn, Evert L.; Boormans, Joost L.; Wijsman, Bart P.; Nooter, Ronald I.; Zwaan, Peter J.; Slaa, Ed te; Meer, Saskia van der; Klaver, Sjoerd O.; Fossion, Laurent M.C.L.; Bos, Siebe D.; Melick, Harm H.E.van; Leliveld, Anna M.; Meijer, Richard P.; Vis, André N.; Molijn, Gerard J.; Berendsen, Chris L.; Oddens, Jorg R.; RACE Study Group (Elsevier, 2021-05)

Background: Radical cystectomy with pelvic lymph node dissection (PLND) and urinary diversion in patients with bladder cancer is known for its high risk of complications. Although open radical cystectomy (ORC) is regarded ...
A systematic review of classifications systems to determine complexity of patient care needs in palliative care

Grant, Matthew; de Graaf, Everlien; Teunissen, Saskia (SAGE Publications Ltd, 2021-04)

BACKGROUND: Providing the right care for each individual patient is a key element of quality palliative care. Complexity is a relatively new concept, defined as the nature of patients' situations and the extent of resulting ...
Implementation of a first-trimester prognostic model to improve screening for gestational diabetes mellitus

RESPECT 2 study group (BioMed Central, 2021-04-13)

BACKGROUND: Improvement in the accuracy of identifying women who are at risk to develop gestational diabetes mellitus (GDM) is warranted, since timely diagnosis and treatment improves the outcomes of this common pregnancy ...
Telefonische triage bij acute thoracale klachten

Wouters, Loes; Zwart, Dorien; Erkelens, Daphne; Huijsmans, Marlies; Hoes, Arno; Damoiseaux, Roger; Rutten, F. H.; de Groot, E. (Bohn Stafleu van Loghum, 2021-05)

Sinds 2011 gebruiken veel huisartsenposten de Nederlandse Triage Standaard (NTS) als beslishulp voor telefonische triage. Doordat het verhaal van de patiënt vaak niet in de starre structuur van de NTS te passen is, merken ...

Now showing items 16481-16500 of 40729