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Now showing items 16461-16480 of 40729

Author Correction: Functional connectome differences in individuals with hallucinations across the psychosis continuum

Schutte, Maya J L; Bohlken, Marc M; Collin, Guusje; Abramovic, Lucija; Boks, Marco P M; Cahn, Wiepke; Dauwan, Meenakshi; van Dellen, Edwin; van Haren, Neeltje E M; Hugdahl, Kenneth; Koops, Sanne; Mandl, René C W; Sommer, Iris E C (Nature Publishing Group, 2021-04-14)

Correction to: Scientific Reports https://doi.org/10.1038/s41598-020-80657-8, published online 13 January 2021
Clinical, Biochemical and Genetic Variables Associated With Metabolic Syndrome in Patients With Schizophrenia Spectrum Disorders Using Second-Generation Antipsychotics: A Systematic Review

Sneller, Marius H; de Boer, Nini; Everaars, Sophie; Schuurmans, Max; Guloksuz, Sinan; Cahn, Wiepke; Luykx, Jurjen J (Frontiers Research Foundation, 2021-03-29)

Background: Individuals with severe mental illness experience increased morbidity and mortality compared to the general population. Adverse effects of antipsychotics, including weight gain, may contribute to the development ...
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

ENIGMA-CNV Working Group (Nature Publishing Group, 2021-03-22)

Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...
Beginning to See the Light: Lessons Learned From the Development of the Circadian System for Optimizing Light Conditions in the Neonatal Intensive Care Unit

Hazelhoff, Esther M; Dudink, Jeroen; Meijer, Johanna H; Kervezee, Laura (Frontiers Media S. A., 2021)

The circadian timing system optimizes health by temporally coordinating behavior and physiology. During mammalian gestation, fetal circadian rhythms are synchronized by the daily fluctuations in maternal body temperature, ...
A Hybrid DCNN-SVM Model for Classifying Neonatal Sleep and Wake States Based on Facial Expressions in Video

Awais, Muhammad; Long, Xi; Yin, Bin; Farooq Abbasi, Saadullah; Akhbarzadeh, Saeed; Lu, Chunmei; Wang, Xinhua; Wang, Laishuan; Zhang, Jiong; Dudink, Jeroen; Chen, Wei (Institute of Electrical and Electronics Engineers Inc., 2021-05)

Sleep is a natural phenomenon controlled by the central nervous system. The sleep-wake pattern, which functions as an essential indicator of neurophysiological organization in the neonatal period, has profound meaning in ...
Radar-based sleep stage classification in children undergoing polysomnography: a pilot-study

de Goederen, R; Pu, S; Silos Viu, M; Doan, D; Overeem, S; Serdijn, W A; Joosten, K F M; Long, X; Dudink, J (Elsevier, 2021-06)

STUDY OBJECTIVES: Unobtrusive monitoring of sleep and sleep disorders in children presents challenges. We investigated the possibility of using Ultra-Wide band (UWB) radar to measure sleep in children. METHODS: Thirty-two ...
Gender-related neuroanatomical differences in alcohol dependence: findings from the ENIGMA Addiction Working Group

Rossetti, Maria Gloria; Patalay, Praveetha; Mackey, Scott; Allen, Nicholas B.; Batalla, Albert; Bellani, Marcella; Chye, Yann; Cousijn, Janna; Goudriaan, Anna E.; Hester, Robert; Hutchison, Kent; Li, Chiang Shan R.; Martin-Santos, Rocio; Momenan, Reza; Sinha, Rajita; Schmaal, Lianne; Sjoerds, Zsuzsika; Solowij, Nadia; Suo, Chao; van Holst, Ruth J.; Veltman, Dick J.; Yücel, Murat; Thompson, Paul M.; Conrod, Patricia; Garavan, Hugh; Brambilla, Paolo; Lorenzetti, Valentina (Elsevier, 2021)

Gender-related differences in the susceptibility, progression and clinical outcomes of alcohol dependence are well-known. However, the neurobiological substrates underlying such differences remain unclear. Therefore, this ...
Strain Tensor Imaging: Cardiac-induced brain tissue deformation in humans quantified with high-field MRI

Sloots, Jacob-Jan; Biessels, Geert Jan; de Luca, Alberto; Zwanenburg, Jaco J M (Academic Press Inc., 2021-08-01)

The cardiac cycle induces blood volume pulsations in the cerebral microvasculature that cause subtle deformation of the surrounding tissue. These tissue deformations are highly relevant as a potential source of information ...
The prognostic value of serological titres for clinical outcomes during treatment and follow-up of patients with chronic Q fever

Buijs, Sheila B.; van Roeden, Sonja E.; van Werkhoven, Cornelis H.; Hoepelman, Andy I.M.; Wever, Peter C.; Bleeker-Rovers, Chantal P.; Oosterheert, Jan Jelrik (Elsevier, 2021-09)

Objectives: We assessed the prognostic value of phase I IgG titres during treatment and follow-up of chronic Q fever. Methods: We performed a retrospective cohort study to analyse the course of phase I IgG titres in chronic ...
Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever

Buijs, Sheila B; Stuart, Sanne K; Oosterheert, Jan Jelrik; Karhof, Steffi; Hoepelman, Andy I M; Renders, Nicole H M; van Petersen, André S; Bleeker-Rovers, Chantal P; Wever, Peter C; Koning, Olivier H J (Springer-Verlag, 2021-07)

We evaluated the long-term serological follow-up of patients with vascular risk factors for chronic Q fever that were previously Coxiella burnetii seropositive. C. burnetii phase I IgG titers were reevaluated in patients ...
Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials

Axfors, Cathrine; Schmitt, Andreas M; Janiaud, Perrine; Van't Hooft, Janneke; Abd-Elsalam, Sherief; Abdo, Ehab F; Abella, Benjamin S; Akram, Javed; Amaravadi, Ravi K; Angus, Derek C; Arabi, Yaseen M; Azhar, Shehnoor; Baden, Lindsey R; Baker, Arthur W; Belkhir, Leila; Benfield, Thomas; Berrevoets, Marvin A H; Chen, Cheng-Pin; Chen, Tsung-Chia; Cheng, Shu-Hsing; Cheng, Chien-Yu; Chung, Wei-Sheng; Cohen, Yehuda Z; Cowan, Lisa N; Dalgard, Olav; de Almeida E Val, Fernando F; de Lacerda, Marcus V G; de Melo, Gisely C; Derde, Lennie; Dubee, Vincent; Elfakir, Anissa; Gordon, Anthony C; Hernandez-Cardenas, Carmen M; Hills, Thomas; Hoepelman, Andy I M; Huang, Yi-Wen; Igau, Bruno; Jin, Ronghua; Jurado-Camacho, Felipe; Khan, Khalid S; Kremsner, Peter G; Kreuels, Benno; Kuo, Cheng-Yu; Le, Thuy; Lin, Yi-Chun; Lin, Wu-Pu; Lin, Tse-Hung; Lyngbakken, Magnus Nakrem; McArthur, Colin; Weehuizen, Jesper M; hoepelman (Nature Publishing Group, 2021-04-15)

Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate ...
Clinically relevant potential drug-drug interactions in intensive care patients: A large retrospective observational multicenter study

de Lange, Prof.dr. D.W. (Dylan) (Elsevier, 2021-04)

PURPOSE: Potential drug-drug interactions (pDDIs) may harm patients admitted to the Intensive Care Unit (ICU). Due to the patient's critical condition and continuous monitoring on the ICU, not all pDDIs are clinically ...
Identification of Novel Neurocircuitry Through Which Leptin Targets Multiple Inputs to the Dopamine System to Reduce Food Reward Seeking

Omrani, Azar; de Vrind, Veronne A J; Lodder, Bart; Stoltenborg, Iris; Kooij, Karlijn; Wolterink-Donselaar, Inge G; Luijendijk-Berg, Mieneke C M; Garner, Keith M; Van't Sant, Lisanne J; Rozeboom, Annemieke; Dickson, Suzanne L; Meye, Frank J; Adan, Roger A H (Elsevier, 2021-12-15)

BACKGROUND: Leptin reduces the motivation to obtain food by modulating activity of the mesolimbic dopamine (DA) system upon presentation of cues that predict a food reward. Although leptin directly reduces the activity of ...
Efficacy and safety of suvratoxumab for prevention of Staphylococcus aureus ventilator-associated pneumonia (SAATELLITE): a multicentre, randomised, double-blind, placebo-controlled, parallel-group, phase 2 pilot trial

COMBACTE Consortium and the SAATELLITE Study Group (Elsevier Limited, 2021-09)

BACKGROUND: Staphylococcus aureus remains a common cause of ventilator-associated pneumonia, with little change in incidence over the past 15 years. We aimed to evaluate the efficacy of suvratoxumab, a monoclonal antibody ...
Ranking of 10 legumes according to the prevalence of sensitization as a parameter to characterize allergenic proteins

Smits, Mark; Verhoeckx, Kitty; Knulst, André; Welsing, Paco; de Jong, Aard; Houben, Geert; Le, Thuy My (Elsevier, 2021-01)

Predicting the allergenicity of novel proteins is challenging due to the absence of validated predictive methods and a well-defined reference set of proteins. The prevalence of sensitization could be a parameter to select ...
Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies

Helsinki Stroke, Study Dutch Parelsnoer Institute-Cerebrovascular Accident (CVA) Study Group; National Institute of Neurological Disorders and Stroke (NINDS) Stroke Genetics Network; UK DNA Lacunar Stroke Study Investigators; International Stroke Genetics Consortium (Elsevier Limited, 2021-05)

BACKGROUND: The genetic basis of lacunar stroke is poorly understood, with a single locus on 16q24 identified to date. We sought to identify novel associations and provide mechanistic insights into the disease. METHODS: ...
Accelerated aging in the brain, epigenetic aging in blood, and polygenic risk for schizophrenia

Teeuw, Jalmar; Ori, Anil P S; Brouwer, Rachel M; de Zwarte, Sonja M C; Schnack, Hugo G; Hulshoff Pol, Hilleke E; Ophoff, Roel A (Elsevier, 2021-05)

Schizophrenia patients show signs of accelerated aging in cognitive and physiological domains. Both schizophrenia and accelerated aging, as measured by MRI brain images and epigenetic clocks, are correlated with increased ...
Predisposition to cancer in children and adolescents

Kratz, Christian P; Jongmans, Marjolijn C; Cavé, Hélène; Wimmer, Katharina; Behjati, Sam; Guerrini-Rousseau, Lea; Milde, Till; Pajtler, Kristian W; Golmard, Lisa; Gauthier-Villars, Marion; Jewell, Rosalyn; Duncan, Catriona; Maher, Eamonn R; Brugieres, Laurence; Pritchard-Jones, Kathy; Bourdeaut, Franck (Elsevier, 2021-02)

Childhood malignancies are rarely related to known environmental exposures, and it has become increasingly evident that inherited genetic factors play a substantial causal role. Large-scale sequencing studies have shown ...
Von Willebrand Factor Multimer Densitometric Analysis: Validation of the Clinical Accuracy and Clinical Implications in von Willebrand Disease

Boender, Johan; Atiq, Ferdows; Cnossen, Marjon H.; Van Der Bom, Johanna G.; Fijnvandraat, Karin; De Meris, Joke; De Maat, Moniek P.M.; Van Galen, Karin P.M.; Laros-Van Gorkom, Britta A.P.; Meijer, Karina; Eikenboom, Jeroen; Leebeek, Frank W.G. (Wolters Kluwer Health, 2021-03)

Von Willebrand factor (VWF) multimer analysis is important in the classification of von Willebrand disease (VWD). Current visual VWF multimer analysis is time consuming and inaccurate in detecting subtle changes in multimer ...
Technique of open and minimally invasive intrathoracic reconstruction following esophagectomy-an expert consensus based on a modified Delphi process

Bartella, Isabel; Fransen, Laura F C; Gutschow, Christian A; Bruns, Christiane J; van Berge Henegouwen, Mark L; Chaudry, M Asif; Cheong, Edward; Cuesta, Miguel A; Van Daele, Elke; Gisbertz, Suzanne S; van Hillegersberg, Richard; Hölscher, Arnulf; Mercer, Stuart; Moorthy, Krishna; Nafteux, Philippe; Nilsson, Magnus; Pattyn, Piet; Piessen, Guillaume; Räsanen, Jari; Rosman, Camiel; Ruurda, Jelle P; Schneider, Paul M; Sgromo, Bruno; Nieuwenhuijzen, Grard A; Luyer, Misha D P; Schröder, Wolfgang (Wiley-Blackwell, 2021-11-11)

BACKGROUND: In recent years, minimally invasive Ivor Lewis (IL) esophagectomy with high intrathoracic anastomosis has emerged as surgical standard of care for esophageal cancer in expert centers. Alongside this process, ...

Now showing items 16461-16480 of 40729