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Now showing items 16401-16420 of 40729

Diagnostic accuracy of [ 99mTc]Tc-tilmanocept compared to [ 99mTc]Tc-nanocolloid for sentinel lymph node identification in early-stage oral cancer

Mahieu, Rutger; den Toom, Inne J; van Rooij, Rob; van Es, Robert J J; Hobbelink, Monique G G; Krijger, Gerard C; Tijink, Bernard M; de Keizer, Bart; de Bree, Remco (Wiley-Blackwell, 2021-11)

This study compares sentinel lymph node identification using [99m Tc]Tc-tilmanocept to [99m Tc]Tc-nanocolloid in early-stage oral cancer patients In those who underwent lymphoscintigraphy using both radiotracers, presence ...
Quantitative magnetic resonance imaging of the brachial plexus shows specific changes in nerve architecture in chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy and motor neuron disease

van Rosmalen, Marieke; Goedee, H Stephan; Derks, Rosina; Asselman, Fay-Lynn; Verhamme, Camiel; de Luca, Alberto; Hendrikse, J; van der Pol, W Ludo; Froeling, Martijn (Wiley-Blackwell, 2021-08)

Background: The immunological pathophysiologies of chronic inflammatory demyelinating polyneuropathy (CIDP) and multifocal motor neuropathy (MMN) differ considerably, but neither has been elucidated completely. Quantitative ...
The global dissemination of hospital clones of Enterococcus faecium

Enterococcal Group (BioMed Central, 2021-12)

BACKGROUND: The hospital-adapted A1 group of Enterococcus faecium remains an organism of significant concern in the context of drug-resistant hospital-associated infections. How this pathogen evolves and disseminates remains ...
Clinical Validation of Whole Genome Sequencing for Cancer Diagnostics

Roepman, Paul; de Bruijn, Ewart; van Lieshout, Stef; Schoenmaker, Lieke; Boelens, Mirjam C.; Dubbink, Hendrikus J.; Geurts-Giele, Willemina R.R.; Groenendijk, Floris H.; Huibers, Manon M.H.; Kranendonk, Mariëtte E.G.; Roemer, Margaretha G.M.; Samsom, Kris G.; Steehouwer, Marloes; de Leng, Wendy W.J.; Hoischen, Alexander; Ylstra, Bauke; Monkhorst, Kim; van der Hoeven, Jacobus J.M.; Cuppen, Edwin (Elsevier, 2021-07)

Whole genome sequencing (WGS) using fresh-frozen tissue and matched blood samples from cancer patients may become the most complete genetic tumor test. With the increasing availability of small biopsies and the need to ...
Specialized nutrition improves muscle function and physical activity without affecting chemotherapy efficacy in C26 tumour-bearing mice

Wijler, Liza A; Raats, Danielle A E; Elias, Sjoerd G; Dijk, Francina J; Quirindongo, Hanil; May, Anne M; Furber, Matthew J W; Dorresteijn, Bram; van Dijk, Miriam; Kranenburg, Onno (Wiley-Blackwell, 2021-06)

Background: Skeletal muscle wasting and fatigue are commonly observed in cancer patients receiving chemotherapy and associated with reduced treatment outcome and quality of life. Nutritional support may mitigate these side ...
Vroegtijdige herkenning is belangrijk bij longfibrose

Geelhoed, Miranda; van den Haak, Harry; Damoiseaux, Roger; Miedema, Jelle; Muris, Jean (Bohn Stafleu van Loghum, 2021-03)

Longfibrose is zeldzaam en wordt dikwijls pas laat herkend, wanneer er vaak al substantiële longschade opgetreden is. Het is belangrijk dat huisartsen longfibrose vroegtijdig herkennen, want nieuwe therapeutische mogelijkheden ...
Effects of linagliptin vs glimepiride on cognitive performance in type 2 diabetes: results of the randomised double-blind, active-controlled CAROLINA-COGNITION study

Biessels, Geert Jan; Verhagen, Chloë; Janssen, Jolien; van den Berg, Esther; Wallenstein, Gudrun; Zinman, Bernard; Espeland, Mark A.; Johansen, Odd Erik (Springer-Verlag, 2021-06)

Aims/hypothesis: Type 2 diabetes, particularly with concomitant CVD, is associated with an increased risk of cognitive impairment. We assessed the effect on accelerated cognitive decline (ACD) of the DPP-4 inhibitor ...
Plasma Ferritin as Marker of Macrophage Activation-Like Syndrome in Critically Ill Patients With Community-Acquired Pneumonia

MARS Consortium (Lippincott Williams & Wilkins, 2021-11-01)

OBJECTIVES: Plasma ferritin levels above 4,420 ng/mL have been proposed as a diagnostic marker for macrophage activation-like syndrome in sepsis and used for selection of sepsis patients for anti-inflammatory therapy. We ...
The association of circulating amylin with β-amyloid in familial Alzheimer's disease

Ly, Han; Verma, Nirmal; Sharma, Savita; Kotiya, Deepak; Despa, Sanda; Abner, Erin L; Nelson, Peter T; Jicha, Gregory A; Wilcock, Donna M; Goldstein, Larry B; Guerreiro, Rita; Brás, José; Hanson, Angela J; Craft, Suzanne; Murray, Andrew J; Biessels, Geert Jan; Troakes, Claire; Zetterberg, Henrik; Hardy, John; Lashley, Tammaryn; Aesg; Despa, Florin (Wiley, 2021)

Introduction: This study assessed the hypothesis that circulating human amylin (amyloid-forming) cross-seeds with amyloid beta (Aβ) in early Alzheimer's disease (AD). Methods: Evidence of amylin-AD pathology interaction ...
Cognitive impairment in patients with cerebrovascular disease: A white paper from the links between stroke ESO Dementia Committee

Verdelho, Ana; Wardlaw, Joanna; Pavlovic, Aleksandra; Pantoni, Leonardo; Godefroy, Olivier; Duering, Marco; Charidimou, Andreas; Chabriat, Hugues; Biessels, Geert Jan (SAGE Publications Inc., 2021-03-01)

Purpose: Many daily-life clinical decisions in patients with cerebrovascular disease and cognitive impairment are complex. Evidence-based information sustaining these decisions is frequently lacking. The aim of this paper ...
Population Pharmacokinetics of Docetaxel, Paclitaxel, Doxorubicin and Epirubicin in Pregnant Women with Cancer: A Study from the International Network of Cancer, Infertility and Pregnancy (INCIP)

Janssen, Julie M; Van Calsteren, Kristel; Dorlo, Thomas P C; Halaska, Michael J; Fruscio, Robert; Ottevanger, Petronella; Schröder, Carolien P; Boere, Ingrid; Witteveen, Petronella O; Painter, Rebecca C; Bekkers, Ruud; Drochytek, Vit; Beijnen, Jos H; Huitema, Alwin D R; Amant, Frederic C H (Adis, 2021-06)

BACKGROUND: Based on reassuring short-term foetal and maternal safety data, there is an increasing trend to administer chemotherapy during the second and third trimesters of pregnancy. The pharmacokinetics (PK) of drugs ...
The attributive value of comprehensive surgical staging in clinically early-stage epithelial ovarian carcinoma: A systematic review and meta-analysis

van de Vorst, Renée E W M; Hoogendam, Jacob P; van der Aa, Maaike A; Witteveen, Petronella O; Zweemer, Ronald P; Gerestein, Cornelis G (Academic Press Inc., 2021-06)

BACKGROUND: Tumor positivity and upstaging rates from various surgical staging steps performed in clinically early-stage epithelial ovarian carcinoma (EOC) vary widely in literature. AIM: To quantify tumor positivity and ...
In Vitro Systematic Drug Testing Reveals Carboplatin, Paclitaxel, and Alpelisib as a Potential Novel Combination Treatment for Adult Granulosa Cell Tumors

Roze, Joline; Sendino Garví, Elena; Stelloo, Ellen; Stangl, Christina; Sereno, Ferdinando; Duran, Karen; Groeneweg, Jolijn; Paijens, Sterre; Nijman, Hans; van Meurs, Hannah; van Lonkhuijzen, Luc; Piek, Jurgen; Lok, Christianne; Jonges, Geertruida; Witteveen, Petronella; Verheijen, René; van Haaften, Gijs; Zweemer, Ronald; Monroe, Glen (Multidisciplinary Digital Publishing Institute (MDPI), 2021-02-01)

Adult granulosa cell tumors (AGCTs) arise from the estrogen-producing granulosa cells. Treatment of recurrence remains a clinical challenge, as systemic anti-hormonal treatment or chemotherapy is only effective in selected ...
Development and testing of a tailored online fertility preservation decision aid for female cancer patients

van den Berg, Michelle; van der Meij, Elleke; Bos, Annelies M E; Boshuizen, Marieke C S; Determann, Domino; van Eekeren, Ramon R J P; Lok, Christianne A R; Schaake, Eva E; Witteveen, Petronella O; Wondergem, Marielle J; Braat, Didi D M; Beerendonk, Catharina C M; Hermens, Rosella P M G (John Wiley & Sons Inc., 2021-03)

BACKGROUND: Decision making regarding future fertility can be very difficult for female cancer patients. To support patients in decision making, fertility preservation decision aids (DAs) are being developed. However, to ...
[18F]FDG and [18F]FES positron emission tomography for disease monitoring and assessment of anti-hormonal treatment eligibility in granulosa cell tumors of the ovary

Roze, Joline F; van Meurs, Hannah S; Monroe, Glen R; Veldhuis, Wouter B; van Lonkhuijzen, Luc R C W; Bennink, Roel J; Groeneweg, Jolijn W; Witteveen, Petronella O; Jonges, Geertruida N; Zweemer, Ronald P; Braat, Arthur J A T (Impact Journals, 2021-03-30)

PURPOSE: Adult granulosa cell tumors (AGCTs) of the ovary represent a rare malignancy in which timing and choice of treatment is a clinical challenge. This study investigates the value of FDG-PET/CT and FES-PET/CT in ...
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

LifeTime Community Working Groups (Nature Research, 2021-04-01)

Correction to: Nature https://doi.org/10.1038/s41586-020-2715-9Published online 07 September 2020
Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling

Robinson, Ross A.; Griffiths, Samuel C.; van de Haar, Lieke L.; Malinauskas, Tomas; van Battum, Eljo Y.; Zelina, Pavol; Schwab, Rebekka A.; Karia, Dimple; Malinauskaite, Lina; Brignani, Sara; van den Munkhof, Marleen H.; Düdükcü, Özge; De Ruiter, Anna A.; Van den Heuvel, Dianne M.A.; Bishop, Benjamin; Elegheert, Jonathan; Aricescu, A. Radu; Pasterkamp, R. Jeroen; Siebold, Christian (Elsevier, 2021-04-15)

During cell migration or differentiation, cell surface receptors are simultaneously exposed to different ligands. However, it is often unclear how these extracellular signals are integrated. Neogenin (NEO1) acts as an ...
Alignment between outcomes and minimal clinically important differences in the Dutch type 2 diabetes mellitus guideline and healthcare professionals' preferences

Dankers, Marloes; Nelissen-Vrancken, Marjorie H J M G; Hart, Bertien H; Lambooij, Anke C; van Dijk, Liset; Mantel-Teeuwisse, Aukje K (Wiley-Blackwell Publishing Ltd, 2021-06)

To evaluate the clinical benefit of new medicines for type 2 diabetes mellitus (T2DM), the Dutch guideline committee T2DM in primary care established the importance of outcomes and minimal clinically important differences ...
The impact of the new Dutch guideline on cardiovascular risk management in patients with COPD: a retrospective study

Nies, Lonneke Me; Akker, Ingrid Looijmans-van den; Rozendaal, Liesbeth; Baar, Brenda; Vos, Rimke C; Hart, Huberta E (Royal College of General Practitioners, 2021-01)

Background: Patients with chronic obstructive pulmonary disease (COPD) have an independent increased risk of cardiovascular (CV) disease. Cardiovascular risk (CVR) assessment should be offered to all patients with COPD, ...
Type 2 diabetes and COPD: treatment in the right healthcare setting? An observational study

Willink, R P; Vos, Rimke C; Looijmans-van den Akker, I; Hart, Huberta E (BioMed Central, 2021-04-20)

Background: Type 2 diabetes (T2DM) and COPD are chronic medical conditions, for which patients need lifelong healthcare. The aim of this study is to examine in which healthcare setting patients with T2DM and COPD receive ...

Now showing items 16401-16420 of 40729