Diagnostic accuracy of [ 99mTc]Tc-tilmanocept compared to [ 99mTc]Tc-nanocolloid for sentinel lymph node identification in early-stage oral cancer

Abstract

This study compares sentinel lymph node identification using [99m Tc]Tc-tilmanocept to [99m Tc]Tc-nanocolloid in early-stage oral cancer patients In those who underwent lymphoscintigraphy using both radiotracers, presence of nodal metastasis was correctly identified by either radiotracer Sentinel lymph node biopsy using [99mTc]Tc-tilmanocept reached a sensitivity of 83.3% and negative predictive value of 93.3% Accuracy of sentinel lymph node biopsy using [99mTc]Tc-tilmanocept is comparable to using [99mTc]Tc-nanocolloid Tilmanocept may be an alternative for nanocolloid in sentinel lymph node biopsy.