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Now showing items 15801-15820 of 40729

Trends in home dialysis use differ among age categories in past two decades: A Dutch registry study

Bonenkamp, Anna A.; Hoekstra, Tiny; Hemmelder, Marc H.; van Eck van der Sluijs, Anita; Abrahams, Alferso C.; van Ittersum, Frans J.; van Jaarsveld, Brigit C. (Wiley-Blackwell, 2022-01)

Background: Although the number of patients with end-stage kidney disease is growing, the number of patients who perform dialysis at home has decreased during the past two decades. The aim of this study was to explore time ...
Good practices for dialysis education, treatment, and eHealth: A scoping review

Van Eck Van Der Sluijs, Anita; Vonk, Sanne; Van Jaarsveld, Brigit C.; Bonenkamp, Anna A.; Abrahams, Alferso C. (Public Library of Science, 2021-08)

Background Recommendations regarding dialysis education and treatment are provided in various (inter)national guidelines, which should ensure that these are applied uniformly in nephrology and dialysis centers. However, ...
Defining key outcomes to evaluate performance of newborn screening programmes for cystic fibrosis

For the European CF Society Neonatal Screening Working Group (ECFS NSWG) (Elsevier, 2021-09)
3D gastruloids: a novel frontier in stem cell-based in vitro modeling of mammalian gastrulation

van den Brink, Susanne C.; van Oudenaarden, Alexander (Elsevier Limited, 2021-09)

3D gastruloids, aggregates of embryonic stem cells that recapitulate key aspects of gastrula-stage embryos, have emerged as a powerful tool to study the early stages of mammalian post-implantation development in vitro. ...
Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns

Bollen, Yannik; Stelloo, Ellen; van Leenen, Petra; van den Bos, Myrna; Ponsioen, Bas; Lu, Bingxin; van Roosmalen, Markus J.; Bolhaqueiro, Ana C.F.; Kimberley, Christopher; Mossner, Maximilian; Cross, William C.H.; Besselink, Nicolle J.M.; van der Roest, Bastiaan; Boymans, Sander; Oost, Koen C.; de Vries, Sippe G.; Rehmann, Holger; Cuppen, Edwin; Lens, Susanne M.A.; Kops, Geert J.P.L.; Kloosterman, Wigard P.; Terstappen, Leon W.M.M.; Barnes, Chris P.; Sottoriva, Andrea; Graham, Trevor A.; Snippert, Hugo J.G. (Nature Research, 2021-08)

Central to tumor evolution is the generation of genetic diversity. However, the extent and patterns by which de novo karyotype alterations emerge and propagate within human tumors are not well understood, especially at ...
ZFP36 family members regulate the pro-inflammatory features of psoriatic dermal fibroblasts

Angiolilli, Chiara; Leijten, Emmerik F A; Bekker, Cornelis P J; Eeftink, Ella; Giovannone, Barbara; Nordkamp, Michel Olde; van der Wal, Marlot; Thijs, Judith L; Vastert, Sebastiaan J; van Wijk, Femke; Radstake, Timothy R D J; van Loosdregt, Jorg (Elsevier, 2022-02)

Dermal fibroblasts are strategically positioned underneath the basal epidermis layer to support keratinocyte proliferation and extracellular matrix production. In inflammatory conditions, these fibroblasts produce cytokines ...
Well-Differentiated Bronchopulmonary Neuroendocrine Tumors: More Than One Entity

DutchMEN Study Group (Elsevier, 2021-11)

Introduction: Until now, well-differentiated bronchopulmonary neuroendocrine tumors (bpNET) occurring either sporadically (sp-bpNET) or in the context of multiple endocrine neoplasia type 1 (MEN1) and diffuse idiopathic ...
An in-silico assessment of the dosimetric benefits of MR-guided radiotherapy for esophageal cancer patients

Boekhoff, Mick; Defize, Ingmar; Borggreve, Alicia; van Hillegersberg, Richard; Kotte, Alexis; Lagendijk, Jan; van Lier, Astrid; Ruurda, Jelle; Takahashi, Noriyoshi; Mook, Stella; Meijer, Gert (Elsevier Ireland Ltd, 2021-09)

Purpose: To assess the dosimetric benefits of online MR-guided radiotherapy (MRgRT) for esophageal cancer patients and to assess how these benefits could be translated into a local boosting strategy to improve future ...
Risk Factors for Tumor Positive Resection Margins After Neoadjuvant Chemoradiotherapy for Esophageal Cancer: Results from the Dutch Upper GI Cancer Audit: A Nationwide Population-Based Study

Dutch Upper GI Cancer Audit Group (Lippincott Williams & Wilkins, 2023-02)

Objective: To identify risk factors for tumor positive resection margins after neoadjuvant chemoradiotherapy (nCRT) followed by esophagectomy for esophageal cancer. Summary Background Data: Esophagectomy after nCRT is ...
Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids

Hamdan, Firas; Ylösmäki, Erkko; Chiaro, Jacopo; Giannoula, Yvonne; Long, Maeve; Fusciello, Manlio; Feola, Sara; Martins, Beatriz; Feodoroff, Michaela; Antignani, Gabriella; Russo, Salvatore; Kari, Otto; Lee, Moon; Järvinen, Petrus; Nisen, Harry; Kreutzman, Anna; Leusen, Jeanette; Mustjoki, Satu; McWilliams, Thomas G; Grönholm, Mikaela; Cerullo, Vincenzo (BioMed Central Ltd., 2021-08-06)

BACKGROUND: Despite the success of immune checkpoint inhibitors against PD-L1 in the clinic, only a fraction of patients benefit from such therapy. A theoretical strategy to increase efficacy would be to arm such antibodies ...
SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging

Steensma, Bart R.; Meliado, Ettore F.; Luijten, Peter; Klomp, Dennis W. J.; van den Berg, Cornelis A. T.; Raaijmakers, Alexander J. E. (John Wiley & Sons Inc., 2021-07)

Purpose To investigate inter-subject variability of B1+, SAR and temperature rise in a database of human models using a local transmit array for 7 T cardiac imaging. Methods Dixon images were acquired of 14 subjects and ...
(Ex-)breast cancer patients with (pre-existing) symptoms of anxiety and/or depression experience higher barriers to contact health care providers during the COVID-19 pandemic

UMBRELLA Study Group (Springer New York, 2021-04)

Purpose: To identify factors associated with (perceived) access to health care among (ex-)breast cancer patients during the COVID-19 pandemic. Methods: Cross-sectional study within a large prospective, multicenter cohort ...
A single setup approach for the MRI-based measurement and validation of the transfer function of elongated medical implants

Stijnman, Peter R. S.; Erturk, M. Arcan; van den Berg, Cornelis A. T.; Raaijmakers, Alexander J. E. (John Wiley & Sons Inc., 2021-11)

Purpose: To propose a single setup using the MRI to both measure and validate the transfer function (TF) of linear implants. Conventionally, the TF of an implant is measured in one bench setup and validated using another. ...
99mTc-HDP bone scintigraphy confirming parathyroid hormone-related peptide paraneoplastic syndrome in metastatic breast cancer

Braat, Arthur J.A.T.; Heerma van Voss, Marise R.; Bijlsma, Rhodé M. (Elsevier Limited, 2021-05)
Rapid 2D variable flip angle method for accurate and precise T1 measurements over a wide range of T1 values

Lena, Beatrice; Bos, Clemens; Ferrer, Cyril J; Moonen, Chrit T W; Viergever, Max A; Bartels, Lambertus W (John Wiley & Sons Inc., 2021-08)

Purpose: To perform dynamic T 1 mapping using a 2D variable flip angle (VFA) method, a correction for the slice profile effect is needed. In this work we investigated the impact of flip angle selection and excitation RF ...
Hypotension during endovascular treatment under general anesthesia for acute ischemic stroke

MR CLEAN Registry Investigators (Public Library of Science, 2021-06-23)

Objective The effect of anesthetic management (general anesthesia [GA], conscious sedation, or local anesthesia) on functional outcome and the role of blood pressure management during endovascular treatment (EVT) for acute ...
Improving phase-based conductivity reconstruction by means of deep learning-based denoising of B 1 + phase data for 3T MRI

Jung, Kyu-Jin; Mandija, Stefano; Kim, Jun-Hyeong; Ryu, Kanghyun; Jung, Soozy; Cui, Chuanjiang; Kim, Soo-Yeon; Park, Mina; van den Berg, Cornelis A T; Kim, Dong-Hyun (John Wiley & Sons Inc., 2021-10)

Purpose: To denoise (Formula presented.) phase using a deep learning method for phase-based in vivo electrical conductivity reconstruction in a 3T MR system. Methods: For (Formula presented.) phase deep-learning denoising, ...
Risk stratification in patients with arrhythmogenic cardiomyopathy

Hauer, Richard N.W.; Velthuis, Birgitta K. (Elsevier Ireland Ltd, 2021-09-01)
Towards personalised contrast injection: Artificial-intelligence-derived body composition and liver enhancement in computed tomography

de Jong, Daan J.; Veldhuis, Wouter B.; Wessels, Frank J.; de Vos, Bob; Moeskops, Pim; Kok, Madeleine (MDPI Multidisciplinary Digital Publishing Institute, 2021-02-24)

In contrast-enhanced computed tomography, total body weight adapted contrast injection protocols have proven successful in achieving a homogeneous enhancement of vascular structures and liver parenchyma. However, because ...
Development and internal validation of multivariable prediction models for biochemical failure after MRI-guided focal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer

Willigenburg, Thomas; van Son, Marieke J; van de Pol, Sandrine M G; Eppinga, Wietse S C; Lagendijk, Jan J W; de Boer, Hans C J; Moerland, Marinus A; van der Voort van Zyp, Jochem R N; Peters, Max (Elsevier Ireland Ltd, 2021-09)

Background and purpose: Magnetic resonance-guided focal salvage high-dose-rate brachytherapy (FS-HDR-BT) for radiorecurrent prostate cancer (PCa) shows low toxicity rates. However, biochemical failure (BF) after treatment ...

Now showing items 15801-15820 of 40729