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UMC Repository: Recent submissions

  • Spontaneous Uterine Rupture in Pregnancy After Treatment of Asherman Syndrome 
    Bos, Anouk M.; Vollebregt, Karlijn C.; Hanstede, Miriam F. (Elsevier, 2025-04)
    Study objective: Women with Asherman syndrome are at high risk of recurrent adhesions and pregnancy complications. Spontaneous uterine rupture is a rare but life-threatening complication, associated with severe maternal ...
  • Randomized controlled trials – The what, when, how and why 
    Braga, Luis H.; Farrokhyar, Forough; İrfan Dönmez, M.; Nelson, Caleb P.; Haid, Bernhard; Herbst, Kathy; Garriboli, Massimo; Cascio, Salvatore; Nieuwhof-Leppink, Anka; Kaefer, Martin; Bägli, Darius J.; Kalfa, Nicholas; Ching, Christina; Fossum, Magdalena; Harper, Luke (Elsevier, 2025-04)
    Randomized controlled trials (RCTs) are at the top of the pyramid of evidence as they offer the best answer on the efficacy of a new treatment. RCTs are true experiments in which participants are randomly allocated to ...
  • Dutch Nationwide Multicenter Prospective Cohort of Essure-related Symptomatology after Removal Surgery 
    Maassen, Liselotte W.; van Gastel, Danielle M.; Koks, Carolien AM; Huirne, Judith AF; Koning, Aafke MH; Graziosi, Giuseppe CM; Bouma, Linda S.; Knauff, Erik AH; van Zon-Rabelink, Ingrid AA; Bongers, Marlies Y.; Veersema, Sebastiaan (Elsevier, 2025-04)
    Study Objective: Essure is a hysteroscopic sterilization device that has been used in the Netherlands since 2003. Essure has received a lot of publicity due to many reported symptoms associated with the device. Because of ...
  • Causes of death in people living with HIV: Lessons from five health facilities in Eswatini 
    Mafulu, Yves; Khumalo, Sukoluhle; Williams, Victor; Ndabezitha, Sandile; Nyandoro, Elisha; Ndlovu, Nkosana; Kay, Alexander; Maseko, Khetsiwe; Simelane, Hlobsile; Gwebu, Siphesihle; Musarapasi, Normusa; Mafukidze, Arnold; Bongomin, Pido; Dube, Nduduzo; Buzaalirwa, Lydia; Dube, Nkululeko; Haumba, Samson (AOSIS (Pty) Ltd, 2024)
    Background: Eswatini has a high HIV prevalence in adults and, despite being one of the first countries to achieve the UNAIDS 95-95-95 targets, AIDS-related deaths are still high. Objectives: This study describes the causes ...
  • Chronic pancreatitis 
    Thierens, Naomi DE; Verdonk, Robert C.; Löhr, J. Matthias; van Santvoort, Hjalmar C.; Bouwense, Stefan AW; van Hooft, Jeanin E. (Elsevier, 2024-12-21)
    Chronic pancreatitis is a progressive fibroinflammatory disease primarily caused by a complex interplay of environmental and genetic risk factors. It might result in pancreatic exocrine and endocrine insufficiency, chronic ...
  • Multimodal neurophenomenology of advanced concentration absorption meditation: An intensively sampled case study of Jhana 
    Chowdhury, Avijit; Bianciardi, Marta; Chapdelaine, Eric; Riaz, Omar S.; Timmermann, Christopher; van Lutterveld, Remko; Sparby, Terje; Sacchet, Matthew D. (Academic Press Inc., 2025-01)
    Using a combination of fMRI, EEG, and phenomenology ratings, we examined the neurophenomenology of advanced concentrative absorption meditation, namely jhanas (ACAM-J), in a practitioner with over 23,000 h of meditation ...
  • Imaging flow cytometry reveals divergent mitochondrial phenotypes in mitochondrial disease patients 
    Muffels, Irena J.J.; Rodenburg, Richard; Willemen, Hanneke L.D.; van Haaften-Visser, Désirée; Waterham, Hans; Eijkelkamp, Niels; Fuchs, Sabine A.; van Hasselt, Peter M. (Elsevier, 2025-01-17)
    Traditional classification by clinical phenotype or oxidative phosphorylation (OXPHOS) complex deficiencies often fails to clarify complex genotype-phenotype correlations in mitochondrial disease. A multimodal functional ...
  • Advancements and emerging insights in thoracolumbar spine trauma 
    Neuhoff, Jonathan; Vaccaro, Alex; Oner, Cumhur; Schnake, Klaus; Kandziora, Frank (Elsevier, 2025-01)
  • Perspectives of the medical oncologist regarding adjuvant chemotherapy for pancreatic cancer: An international expert survey and case vignette study 
    Biesma, N. C.; Graus, M. U.J.E.; Cirkel, G. A.; Besselink, M. G.; de Groot, J. W.B.; Koerkamp, B. Groot; Herbschleb, K. H.; Los, M.; Verdonk, R. C.; Wilmink, J. W.; Cervantes, A.; Valle, J. W.; Valkenburg-van Iersel, L. B.J.; Froeling, F. E.M.; Molenaar, I. Q.; Daamen, L. A.; de Vos-Geelen, J.; van Santvoort, H. C.; for the Dutch Pancreatic Cancer Group (W.B. Saunders Ltd, 2025-03)
    Introduction: Adjuvant chemotherapy improves survival in patients with resected pancreatic ductal adenocarcinoma (PDAC). The decision to initiate chemotherapy involves both patient and physician factors, decision-specific ...
  • An Overview of Patient-reported Outcomes for Men with Prostate Cancer: Results from the PIONEER Consortium 
    Remmers, Sebastiaan; Beyer, Katharina; Lalmahomed, Tariq A.; Prinsen, Peter; Horevoorts, Nicole J.E.; Sibert, Nora Tabea; Kowalski, Christoph; Barletta, Francesco; Brunckhorst, Oliver; Gandaglia, Giorgio; van der Voort van Zyp, Jochem R.N.; Smith, Emma J.; Deschamps, Andre; Collette, Laurence; Cornford, Philip; Evans-Axelsson, Susan; N'Dow, James; Hemelrijck, Mieke Van; Roobol, Monique J.; Venderbos, Lionne D.F.; The PIONEER Consortium (Elsevier, 2025-01)
    Background and objective: Patient-reported outcome measures (PROMs) are increasingly being used to capture the patients’ perspective of their functional status and quality of life (QoL). Big data can help us better understand ...
  • Radiotherapy-induced Hypothalamic-Pituitary axis dysfunction in adult Brain, head and neck and skull base tumor patients – A systematic review and Meta-Analysis 
    Paulissen, J. M.J.; Zegers, C. M.L.; Houben, R. M.; Hofstede, D.; Kars, M.; van Santen, H. M.; Hoebers, F. J.P.; De Ruysscher, D. K.M.; Eekers, D. B.P. (Elsevier Ireland Ltd, 2025-03)
    Background and purpose: Radiotherapy for brain, head & neck (HN), and skull base (SB) tumors may deliver significant radiation dose to the hypothalamic-pituitary axis (HPA), leading to impaired functioning of this region ...
  • Measuring health-related quality of life in cardiovascular disease using a novel patient-centred and disease-specific patient-reported outcome measure 
    Singh, Tajinder K.; Ties, Daan; Groot, Hilde E.; Krabbe, Paul F.M.; van der Harst, Pim (Elsevier, 2025-03)
    Background: Assessment of health-related quality of life (HRQoL) in patients with cardiovascular disease (CVD) is impaired by limitations of current patient-reported outcome measures (PROMs). We developed the first ...
  • Towards collaborative data science in mental health research: The ECNP neuroimaging network accessible data repository 
    Khuntia, Adyasha; Buciuman, Madalina Octavia; Fanning, John; Stolicyn, Aleks; Vetter, Clara; Armio, Reetta Liina; From, Tiina; Goffi, Federica; Hahn, Lisa; Kaufmann, Tobias; Laurikainen, Heikki; Maggioni, Eleonora; Martinez-Zalacain, Ignacio; Ruef, Anne; Dong, Mark Sen; Schwarz, Emanuel; Squarcina, Letizia; Andreassen, Ole; Bellani, Marcella; Brambilla, Paolo; Haren, Neeltje van; Hietala, Jarmo; Lawrie, Stephen M.; Soriano-Mas, Carles; Whalley, Heather; Taquet, Maxime; Meisenzahl, Eva; Falkai, Peter; Wiegand, Ariane; Koutsouleris, Nikolaos (2025)
    The current biologically uninformed psychiatric taxonomy complicates optimal diagnosis and treatment. Neuroimaging-based machine learning methods hold promise for tackling these issues, but large-scale, representative ...
  • Incidence and prevalence of traumatic and non-traumatic wounds and burns and access to wound care in Sierra Leone; data from a nationwide household survey (PRESSCO) 2020 
    Vas Nunes, Jonathan H.; van Duinen, Alex J.; Boateng, Daniel; Tommy, Amidu J.; Sankoh, Osman; Grobusch, Martin P.; Bolkan, Håkon A.; for the PRESSCO 2020 study group (Elsevier, 2025-01-15)
    Objectives: This wound section of the PREvalence Study on Surgical COnditions (PRESSCO) determines the incidence and prevalence of wounds and burns in Sierra Leone. It further describes access to wound care and wound-related ...
  • European consensus-based interdisciplinary guideline for melanoma. Part 1: Diagnostics - Update 2024 
    Garbe, Claus; Amaral, Teresa; Peris, Ketty; Hauschild, Axel; Arenberger, Petr; Basset-Seguin, Nicole; Bastholt, Lars; Bataille, Veronique; Brochez, Lieve; del Marmol, Veronique; Dréno, Brigitte; Eggermont, Alexander M.M.; Fargnoli, Maria Concetta; Forsea, Ana Maria; Höller, Christoph; Kaufmann, Roland; Kelleners-Smeets, Nicole; Lallas, Aimilios; Lebbé, Celeste; Leiter, Ulrike; Longo, Caterina; Malvehy, Josep; Moreno-Ramirez, David; Nathan, Paul; Pellacani, Giovanni; Saiag, Philippe; Stockfleth, Eggert; Stratigos, Alexander J.; Van Akkooi, Alexander C.J.; Vieira, Ricardo; Zalaudek, Iris; Lorigan, Paul; Mandala, Mario; On behalf of the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF), and the European Organization for Research and Treatment of Cancer (EORTC) (Elsevier Limited, 2025-01-17)
    This guideline was developed in close collaboration with multidisciplinary experts from the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF) and the European Organization for Research ...
  • Generation and characterization of novel induced pluripotent stem cell (iPSC) lines derived from three symptomatic carriers of a pathogenic MYH11 variant and two non-carrier relatives 
    Atash, Aria; Cramer, Maarten Jan; Mees, Barend; Doevendans, Pieter A.; Sluijter, Joost P.G.; Stillitano, Francesca (Elsevier, 2025-02)
    A novel pathogenic variant in the MYH11 gene (c.4559+1G>A) leading to exon 32 skipping, is a rare cause of familial aortic aneurysms and dissections (fTAAD). The phenotype has proven highly variable with reduced penetrance. ...
  • Vascular ageing manifestations and hypertension in the community 
    Alanis, Guillermo A.; Boutouyrie, Pierre; Abouqateb, Mouad; Bruno, Rosa Maria; Climie, Rachel E.; van Sloten, Thomas; Danchin, Nicolas; Pannier, Bruno; Laurent, Stéphane; Jouven, Xavier; Empana, Jean Philippe (Elsevier, 2025-03)
    Objective: To investigate the association between joint manifestations of vascular ageing (VA) and hypertension. Methods: We used baseline (2008–2012) and follow-up data (up to 2024) from the Paris Prospective Study III, ...
  • Country-Specific Roadmaps for Scaling Up Integrated Care in Belgium, Slovenia, and Cambodia - Lessons Learned from the SCUBY Project 
    Heine, Martin; Martens, Monika; Boateng, Daniel; Ku, Grace Marie; Remmen, Roy; Wouters, Edwin; Chhim, Srean; Ir, Por; Susič, Antonjia Poplas; van Damme, Wim; van Olmen, Josefien; Klipstein-Grobusch, Kerstin; SCUBY consortium (Igitur, Utrecht Publishing and Archiving Services, 2024-12-20)
    INTRODUCTION: The SCUBY project aimed to provide knowledge on the scaling-up of an Integrated Care Package (ICP) for type 2 diabetes and hypertension across three distinct health systems (Cambodia, Slovenia, and Belgium). ...
  • Santander Statement: Towards Global Convergence in Transplantation: Sufficiency, Transparency, and Oversight 
    Participants to the Global Summit in Transplantation, organized by the Organización Nacional de Trasplantes under the Spanish Presidency of the Council of the European Union, the European Directorate for the Quality of Medicines and Healthcare−Council of Europe, the European Society for Organ Transplantation, and The Transplantation Society, co-sponsored by the World Health Organization and supported by the International Society of Nephrology in Santander, Spain, November 9 and 10, 2023 (Lippincott Williams & Wilkins, 2025-01)
  • Early warning systems for identifying severe maternal outcomes: findings from the WHO global maternal sepsis study 
    Chimwaza, Yamikani; Hunt, Alexandra; Oliveira-Ciabati, Livia; Bonnett, Laura; Abalos, Edgardo; Cuesta, Cristina; Souza, João Paulo; Bonet, Mercedes; Brizuela, Vanessa; Lissauer, David; Mohammad Iqbal Aman, Iqbal Aman; Noormal, Bashir; Espinoza, Marisa; Pasquale, Julia; Leroy, Charlotte; Roelens, Kristien; Vandenberghe, Griet; Urlyss Agossou, M. Christian; Keke, Sourou Goufodji; Aguemon, Christiane Tshabu; Apaza Peralta, Patricia Soledad; Altamirano, Víctor Conde; Muñoz, Rosalinda Hernández; Cecatti, José Guilherme; Ribeiro do Valle, Carolina; Batiene, Vincent; Cisse, Kadari; Ouedraogo, Henri Gautier; Cheang, Kannitha; Lam, Phirun; Rathavy, Tung; Simo, Elie; Tebeu, Pierre Marie; Yakana, Emah Irene; Carvajal, Javier; Escobar, María Fernanda; Fernández, Paula; Colmorn, Lotte Berdiin; Langhoff-Roos, Jens; Mereci, Wilson; Vélez, Paola; Eldin, Yasser Salah; Sultan, Alaa; Teklu, Alula M.; Worku, Dawit; Adanu, Richard; Govule, Philip; Kumar, Vijay; Bloemenkamp, Kitty; Rijken, Marcus J.; World Health Organization Global Maternal Sepsis Study Research Group (Elsevier, 2025-01)
    Background: Infections and sepsis are leading causes of morbidity and mortality in women during pregnancy and the post-pregnancy period. Using data from the 2017 WHO Global Maternal Sepsis Study, we explored the use of ...