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Plasma Extracellular Vesicle Serpin G1 and CD14 Levels are Associated with Major Adverse Cardiovascular Events and Major Adverse Limb Events in Patients Undergoing Femoral Endarterectomy

Verwer, M C; Mekke, J M; Timmerman, N; Van Der Pol, Q Y; Frissen, C; Pasterkamp, G; De Borst, G J; Hazenberg, C E V B; De Kleijn, D P V (W.B. Saunders Ltd, 2023-02)

Objective: Plasma extracellular vesicles (EV) are an emerging source of biomarkers for diagnosis and prognosis of cardiovascular disease (CVD). Risk stratification for common adverse events such as major adverse limb events ...
Skin microbiome alters attractiveness to Anopheles mosquitoes

Showering, Alicia; Martinez, Julien; Benavente, Ernest Diez; Gezan, Salvador A; Jones, Robert T; Oke, Catherine; Tytheridge, Scott; Pretorius, Elizabeth; Scott, Darren; Allen, Rachel L; D'Alessandro, Umberto; Lindsay, Steve W; Armour, John A L; Pickett, John; Logan, James G (BioMed Central, 2022-12)

BACKGROUND: Some people produce specific body odours that make them more attractive than others to mosquitoes, and consequently are at higher risk of contracting vector-borne diseases. The skin microbiome can break down ...
Author Correction: A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration (Nature Communications, (2021), 12, 1, (4808), 10.1038/s41467-021-25211-4)

Raso, Andrea; Dirkx, Ellen; Sampaio-Pinto, Vasco; el Azzouzi, Hamid; Cubero, Ryan J.; Sorensen, Daniel W.; Ottaviani, Lara; Olieslagers, Servé; Huibers, Manon M.; de Weger, Roel; Siddiqi, Sailay; Moimas, Silvia; Torrini, Consuelo; Zentillin, Lorena; Braga, Luca; Nascimento, Diana S.; da Costa Martins, Paula A.; van Berlo, Jop H.; Zacchigna, Serena; Giacca, Mauro; De Windt, Leon J. (Nature Publishing Group, 2022-08-25)

In the original version of this Article, the magnified image of the hematoxylin and eosin (H&E) staining in the Figure 1d column labelled “TAC knockout’ was inadvertently replaced with a duplicate of themagnified image of ...
Learning accountable governance: Challenges and perspectives for data-intensive health research networks

Muller, Sam H.A.; Mostert, Menno; van Delden, Johannes J.M.; Schillemans, Thomas; van Thiel, Ghislaine J.M.W. (SAGE Publications Ltd, 2022-11-10)

Current challenges to sustaining public support for health data research have directed attention to the governance of data-intensive health research networks. Accountability is hailed as an important element of trustworthy ...
Regulatory T cells in psoriatic arthritis: an IL-17A-producing, Foxp3intCD161 + RORγt + ICOS + phenotype, that associates with the presence of ADAMTSL5 autoantibodies

Pouw, J. N.Juliëtte; Nordkamp, M. A.M.Michel Olde; van Kempen, T. Tessa; Concepcion, A. N.Arno; van Laar, J. M.Jacob; van Wijk, F. Femke; Spierings, J. Julia; Leijten, E. F.A.Emmerik; Boes, M. Marianne (Nature Publishing Group, 2022-12)

In psoriatic arthritis (PsA), predisposing class I HLA alleles, the presence of synovial clonally proliferated CD8 + T cells and autoantibodies all point towards the loss of immune tolerance. However, the key mechanisms ...
Pancreatoduodenectomy for distal cholangiocarcinoma 13 years after oesophagectomy with gastric tube reconstruction: Report of a case

Biesma, Nanske C.; Te Riele, Wouter W.; Van Santvoort, Hjalmar C.; Molenaar, I. Quintus (BMJ Publishing Group, 2022-02-08)

Advancements in cancer management have led to improved survival in patients with oesophageal cancer. This has resulted in an increased incidence of second primary malignancies with the pancreas as a common secondary cancer ...
The fear of cancer recurrence and progression in patients with pancreatic cancer

for the Dutch Pancreatic Cancer Group (Springer-Verlag, 2022-06)

PURPOSE: It is plausible that patients with pancreatic cancer experience fear of tumor recurrence or progression (FOP). The aim of this study was to compare FOP in patients with pancreatic cancer treated with surgical ...
ASO Author Reflections: The Need for Improvement of the 8th American Joint Committee on Cancer TNM Staging System for Resected Pancreatic Ductal Adenocarcinoma

Schouten, Thijs J.; Daamen, Lois A.; van Santvoort, Hjalmar C.; Molenaar, I. Quintus (Springer New York, 2022-09)
Routine abdominal drainage after distal pancreatectomy: Meta-Analysis

Van Bodegraven, Eduard A.; Van Ramshorst, Tess M.E.; Balduzzi, Alberto; Hilal, Mohammed Abu; Molenaar, I. Quintus; Salvia, Roberto; Van Eijck, Casper; Besselink, Marc G. (John Wiley & Sons Inc., 2022-06-01)
ASO Author Reflections: Nationwide Reflection of Clinical Outcomes in Elderly Patients after Resection of Pancreatic Cancer

Henry, Anne Claire; Schouten, Thijs J.; Daamen, Lois A.; Molenaar, I. Quintus; van Santvoort, Hjalmar C. (Springer New York, 2022-09)
Interobserver Variability in CT-based Morphologic Tumor Response Assessment of Colorectal Liver Metastases

Wesdorp, Nina J.; Kemna, Ruby; Bolhuis, Karen; van Waesberghe, Jan H.T.M.; Nota, Irene M.G.C.; Struik, Femke; Abdennabi, Ikrame Oulad; Phoa, Saffire S.K.S.; van Dieren, Susan; van Amerongen, Martinus J.; Chapelle, Thiery; Dejong, Cornelis H.C.; Engelbrecht, Marc R.W.; Gerhards, Michael F.; Grünhagen, Dirk; van Gulik, Thomas M.; Hermans, John J.; de Jong, Koert P.; Klaase, Joost M.; Liem, Mike S.L.; van Lienden, Krijn P.; Molenaar, I Quintus; Patijn, Gijs A.; Rijken, Arjen M.; Ruers, Theo M.; Verhoef, Cornelis; de Wilt, Johannes H.W.; Swijnenburg, Rutger Jan; Punt, Cornelis J.A.; Huiskens, Joost; Stoker, Jaap; Kazemier, Geert (Radiological Society of North America Inc., 2022-05)

Purpose To evaluate interobserver variability in the morphologic tumor response assessment of colorectal liver metastases (CRLM) managed with systemic therapy and to assess the relation of morphologic response with gene ...
Arterio-ureteral fistula: a nationwide cross-sectional questionnaire analysis

Lock, Tycho M.T.W.; Kamphorst, Kyara; van den Bergh, Roderick C.N.; Moll, Frans L.; de Vries, Jean Paul P.M.; Lo, Rob T.H.; de Kort, Gérard A.P.; Bruijnen, Rutger C.G.; Dik, Pieter; Horenblas, Simon; de Kort, Laetitia M.O. (Springer-Verlag, 2022-03)

Purpose: Arterio-ureteral fistula (AUF) is an uncommon diagnosis, but potentially lethal. Although the number of reports has increased over the past two decades, the true incidence and contemporary urologists’ experience ...
The profile of cognitive impairment and hemodynamic compromise in moyamoya: a single-center prospective cohort study

Kronenburg, Annick; Deckers, Pieter T.; van den Berg, Esther; van Schooneveld, Monique M.; Vonken, Evert Jan; van der Zwan, Albert; van Berckel, Bart N.M.; Yaqub, Maqsood; Otte, Willem; Klijn, Catharina J.M.; Braun, Kees P.J. (American Association of Neurological Surgeons, 2023-01)

OBJECTIVE Patients with moyamoya vasculopathy often experience cognitive impairments. In this prospective single-center study, the authors investigated the profile of neurocognitive impairment and its relation with the ...
Minimum spanning tree analysis of brain networks: A systematic review of network size effects, sensitivity for neuropsychiatric pathology, and disorder specificity

Blomsma, N; de Rooy, B; Gerritse, F; van der Spek, R; Tewarie, P; Hillebrand, A; Otte, W M; Stam, C J; van Dellen, E (MIT Press Journals, 2022-06)

Brain network characteristics' potential to serve as a neurological and psychiatric pathology biomarker has been hampered by the so-called thresholding problem. The minimum spanning tree (MST) is increasingly applied to ...
Rhabdomyosarcoma

Yechieli, Raphael L.; Mandeville, Henry C.; Hiniker, Susan M.; Bernier-Chastagner, Valerie; McGovern, Susan; Scarzello, Giovanni; Wolden, Suzanne; Cameron, Alison; Breneman, John; Fajardo, Raquel Davila; Donaldson, Sarah S. (Wiley-Liss Inc., 2021-05)

Rhabdomyosarcoma is a heterogeneous disease both in presentation and histology. Improvements in a multimodality therapy resulted in the improved overall survival for patients with a low-risk and intermediate-risk disease ...
Perianal/perineal rhabdomyosarcoma: Results of the SIOP MMT 95, Italian RMS 96, and EpSSG RMS 2005 studies

Rogers, Timothy; Zanetti, Ilaria; Coppadoro, Beatrice; Martelli, Hélène; Jenney, Meriel; Minard-Colin, Veronique; Terwisscha van Scheltinga, Sheila E.J.; Skerritt, Clare; Fajardo, Raquel Dávila; Guérin, Florent; Kelsey, Anna; Merks, Johannes H.M.; Mandeville, Henry; Guillén, Gabriela; Glosli, Heidi; De Corti, Federica; Bisogno, Gianni (Wiley-Liss Inc., 2022-09)

BACKGROUND/OBJECTIVES: Rhabdomyosarcoma of the perianal/perineal region (PRMS) is rare, with poor survival and limited understanding of the functional consequences of treatment. DESIGN/METHODS: International Society of ...
Therapy and prognostic significance of regional lymph node involvement in embryonal rhabdomyosarcoma: a report from the European paediatric Soft tissue sarcoma Study Group

Ben-Arush, Myriam; Minard-Colin, Veronique; Scarzello, Giovanni; Fajardo, Raquel D.; Terwisscha Van Scheltinga, Sheila; Bernier, Valérie; Jenney, Meriel; Gallego, Soledad; Zanetti, Ilaria; Cesen, Maja; Merks, Johannes H.M.; Bisogno, Gianni (Elsevier Limited, 2022-09)

Purpose: Regional lymph node disease (N1) is a component of the risk-based treatment stratification in rhabdomyosarcoma (RMS). The purpose of this study was to determine the contribution of nodal disease to the prognosis ...
An International Multicenter Study Exploring Whether Surveillance After Esophageal Cancer Surgery Impacts Oncological and Quality of Life Outcomes (ENSURE)

ENSURE Study Group (Lippincott Williams & Wilkins, 2023-05-01)

OBJECTIVE: To determine the impact of surveillance on recurrence pattern, treatment, survival and health-related quality-of-life (HRQL) following curative-intent resection for esophageal cancer. SUMMARY BACKGROUND DATA: ...
Development and Validation of Risk Prediction Models for Coronary Heart Disease and Heart Failure After Treatment for Hodgkin Lymphoma

de Vries, Simone; Haaksma, Miriam L; Jóźwiak, Katarzyna; Schaapveld, Michael; Hodgson, David C; Lugtenburg, Pieternella J; Krol, Augustinus D G; Petersen, Eefke J; van Spronsen, Dick Johan; Ahmed, Sameera; Hauptmann, Michael; Aleman, Berthe M P; van Leeuwen, Flora E (Lippincott Williams & Wilkins, 2023-01-01)

PURPOSE: Previous efforts to predict absolute risk of treatment-related cardiovascular diseases (CVDs) have mostly focused on childhood cancer survivors. We aimed to develop prediction models for risk of coronary heart ...
A multigenomic liquid biopsy biomarker for neuroendocrine tumor disease outperforms CgA and has surgical and clinical utility

Modlin, I. M.; Kidd, M.; Falconi, M.; Filosso, P. L.; Frilling, A.; Malczewska, A.; Toumpanakis, C.; Valk, G.; Pacak, K.; Bodei, L.; Öberg, K. E. (Oxford University Press, 2021-11)

BACKGROUND: Biomarkers are key tools in cancer management. In neuroendocrine tumors (NETs), Chromogranin A (CgA) was considered acceptable as a biomarker. We compared the clinical efficacy of a multigenomic blood biomarker ...

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