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Now showing items 10961-10980 of 40728

Pediatric Non-Rhabdomyosarcoma Soft Tissue Sarcomas: Standard of Care and Treatment Recommendations from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)

Ferrari, Andrea; Brennan, Bernadette; Casanova, Michela; Corradini, Nadege; Berlanga, Pablo; Schoot, Reineke A.; Ramirez-Villar, Gema L.; Safwat, Akmal; Burrieza, Gabriela Guillen; Dall’igna, Patrizia; Alaggio, Rita; Hjalgrim, Lisa Lyngsie; Gatz, Susanne Andrea; Orbach, Daniel; van Noesel, Max M. (Dove Medical Press Ltd., 2022-09-23)

This paper describes the standard of care for patients with non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) and the therapeutic recommendations developed by the European paediatric Soft tissue sarcoma Study Group (EpSSG). ...
Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience

Milano, Giuseppe Maria; Orbach, Daniel; Casanova, Michela; Berlanga, Pablo; Schoot, Reineke A.; Corradini, Nadege; Brennan, Bernadette; Ramirez-Villar, Gema L.; Lyngsie Hjalgrim, Lisa; van Noesel, Max M.; Alaggio, Rita; Ferrari, Andrea (Wiley-Liss Inc., 2023-02)

Malignant ectomesenchymoma (MEM) is an extremely rare soft tissue tumor typical of young children, currently included in the category of skeletal muscle malignancies and characterized by a neuroblastic component. This study ...
Evaluate the safety and efficacy of dura sealant patch in reducing cerebrospinal fluid leakage following elective cranial surgery (ENCASE II): study protocol for a randomized, two-arm, multicenter trial

ENCASE II study group (BioMed Central, 2022-07-20)

Background: Cerebrospinal fluid (CSF) leakage is a frequent and challenging complication in neurosurgery, especially in the posterior fossa, with a prevalence of 8%. It is associated with substantial morbidity and increased ...
Prevalence, risk factors, and long-term outcomes of cerebral ischemia in hospitalized COVID-19 patients - study rationale and protocol of the CORONIS study: A multicentre prospective cohort study

van Lith, Theresa J; Sluis, Wouter M; Wijers, Naomi T; Meijer, Frederick Ja; Kamphuis-van Ulzen, Karin; de Bresser, Jeroen; Dankbaar, Jan Willem; van den Heuvel, Frederik Ma; Antoni, M Louisa; Mulders-Manders, Catharina M; de Mast, Quirijn; van de Veerdonk, Frank L; Klok, Frederikus A; Tuladhar, Anil M; Cannegieter, Suzanne C; Wermer, Marieke Jh; van der Worp, H Bart; Huisman, Menno V; de Leeuw, Frank-Erik (SAGE Publications Inc., 2022-06)

BACKGROUND: COVID-19 is often complicated by thrombo-embolic events including ischemic stroke. The underlying mechanisms of COVID-19-associated ischemic stroke, the incidence and risk factors of silent cerebral ischemia, ...
Collateral status and recanalization after endovascular treatment for acute ischemic stroke

MR CLEAN Registry Investigators (BMJ Publishing Group, 2023-06)

BACKGROUND: Successful recanalization and good collateral status are associated with good clinical outcomes after endovascular treatment (EVT) for acute ischemic stroke, but the relationships among them are unclear. ...
Malignant infarction after endovascular treatment: Incidence and prediction

Bernsen, Marie Louise E; Kauw, Frans; Martens, Jasper M; van der Lugt, Aad; Yo, Lonneke Sf; van Walderveen, Marianne Aa; Roos, Yvo Bwem; van der Worp, H Bart; Dankbaar, Jan W; Hofmeijer, Jeannette (SAGE Publications Ltd, 2022-02)

BACKGROUND: Early prediction of malignant infarction may guide treatment decisions. For patients who received endovascular treatment, the risk of malignant infarction is unknown and risk factors are unrevealed. AIMS: The ...
Labyrinthine fistulas: Surgical outcomes and an additional diagnostic strategy

Westerhout, Sanne F; Straatman, Louise V; Dankbaar, Jan Willem; Thomeer, Hans G X M (Elsevier, 2022-05)

PURPOSE: To evaluate perioperative findings and audiological and vestibular outcomes in patients operated for cholesteatoma with labyrinthine fistulas. Also to assess radiological fistula size. MATERIALS AND METHODS: ...
Radiological and surgical aspects of round window visibility during cochlear implantation: a retrospective analysis

Jwair, Saad; van Eijden, Job J M; Blijleven, Esther E; Dankbaar, Jan Willem; Thomeer, Hans G X M (Springer-Verlag, 2022-01)

PURPOSE: The round window approach has become the most preferred option for cochlear implant (CI) insertion, however, sometimes it may not be possible due to the (in)visibility of the round window membrane (RWM). We addressed ...
Time Since Stroke Onset, Quantitative Collateral Score, and Functional Outcome After Endovascular Treatment for Acute Ischemic Stroke

MR CLEAN Registry Investigators (Lippincott Williams & Wilkins, 2022-10-11)

BACKGROUND AND OBJECTIVES: In patients with ischemic stroke undergoing endovascular treatment (EVT), time to treatment and collateral status are important prognostic factors and may be correlated. We aimed to assess the ...
Cerebral Collateral Circulation in the Era of Reperfusion Therapies for Acute Ischemic Stroke

Uniken Venema, Simone M; Dankbaar, Jan Willem; van der Lugt, Aad; Dippel, Diederik W J; van der Worp, H Bart (Lippincott Williams & Wilkins, 2022-10)

Clinical outcomes of patients with acute ischemic stroke depend in part on the extent of their collateral circulation. A good collateral circulation has also been associated with greater benefit of intravenous thrombolysis ...
MR Imaging and Clinical Characteristics of Diffuse Glioneuronal Tumor with Oligodendroglioma-like Features and Nuclear Clusters

Benesch, M; Perwein, T; Apfaltrer, G; Langer, T; Neumann, A; Brecht, I B; Schuhmann, M U; Cario, H; Frühwald, M C; Vollert, K; van Buiren, M; Deng, M Y; Seitz, A; Haberler, C; Mynarek, M; Kramm, C; Sahm, F; Robe, P A; Dankbaar, J W; Hoff, K V; Warmuth-Metz, M; Bison, B (American Society of Neuroradiology, 2022-10-01)

BACKGROUND AND PURPOSE: Diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters (DGONC) is a new, molecularly defined glioneuronal CNS tumor type. The objective of the present study was to ...
Prognostic Implications of Uterine Cervical Cancer Regression During Chemoradiation Evaluated by the T-Score in the Multicenter EMBRACE I Study

Lindegaard, Jacob Christian; Petric, Primoz; Schmid, Maximilian Paul; Nesvacil, Nicole; Haie-Meder, Christine; Fokdal, Lars Ulrik; Sturdza, Alina Emiliana; Hoskin, Peter; Mahantshetty, Umesh; Segedin, Barbara; Bruheim, Kjersti; Huang, Fleur; Rai, Bhavana; Cooper, Rachel; van der Steen-Banasik, Elzbieta; Van Limbergen, Erik; Pieters, Bradley Rumwell; Tan, Li Tee; Nout, Remi A.; De Leeuw, Astrid Agatha Catharina; Kirchheiner, Kathrin; Spampinato, Sofia; Jürgenliemk-Schulz, Ina; Tanderup, Kari; Kirisits, Christian; Pötter, Richard (Elsevier, 2022-06-01)

Purpose: A simple scoring system (T-score, TS) for integrating findings from clinical examination and magnetic resonance imaging (MRI) of the primary tumor at diagnosis has shown strong prognostic capability for predicting ...
Microcystic elongated and fragmented (MELF) pattern of invasion: Molecular features and prognostic significance in the PORTEC-1 and -2 trials

van den Heerik, A. S.V.M.; Aiyer, K. T.S.; Stelloo, E.; Jürgenliemk-Schulz, I. M.; Lutgens, L. C.H.W.; Jobsen, J. J.; Mens, J. W.M.; van der Steen-Banasik, E. M.; Creutzberg, C. L.; Smit, V. T.H.B.M.; Horeweg, N.; Bosse, T. (Academic Press Inc., 2022-09)

Objective: Microcystic, elongated fragmented (MELF) pattern of myometrial invasion is a distinct histologic feature occasionally seen in low-grade endometrial carcinomas (EC). The prognostic relevance of MELF invasion was ...
Brachytherapy training survey among radiation oncology residents in Europe

Sturdza, Alina Emiliana; Stephanides, Marianne; Jurgenliemk-Schulz, Ina; Eriksen, Jesper Grau; Benstead, Kim; Hoskin, Peter; Vlad, Stefanel; Escande, Alexandre; Corradini, Stefanie; Knoth, Johannes; Westerveld, Henrike; Tagliaferri, Luca; Najari-Jamali, Dina; Konat-Baska, Katarzyna; Plesinac, Vesna; Tan, Li Tee; Nout, Remi; Strnad, Vratislav; Niehoff, Peter; Pieters, Bradley R.; Tanderup, Kari; Kamrava, Mitchell (Elsevier Ireland Ltd, 2022-12)

UNLABELLED: We aim to investigate the current state of brachytherapy (BT) training among the radiation oncology trainees in Europe. MATERIAL AND METHODS: A 22-question online survey based on the one by the American Association ...
Defining Substantial Lymphovascular Space Invasion in Endometrial Cancer

Peters, Elke E.M.; León-Castillo, Alicia; Smit, Vincent T.H.B.M.; Boennelycke, Marie; Hogdall, Estrid; Hogdall, Claus; Creutzberg, Carien; Jürgenliemk-Schulz, Ina M.; Jobsen, Jan J.; Mens, Jan Willem M.; Lutgens, Ludy C.H.W.; Van Der Steen-Banasik, Elzbieta M.; Ortoft, Gitte; Bosse, Tjalling; Nout, Remi (Lippincott Williams & Wilkins, 2022-05)

Lymphovascular space invasion (LVSI) occurs in a minority of endometrial cancer (EC) cases, and the extent of LVSI is an important risk factor for recurrence and/or metastases. Our aim was to improve the reproducibility ...
H&N and Skin (HNS) GEC-ESTRO Working Group critical review of recommendations regarding prescription depth, bolus thickness and maximum dose in skin superficial brachytherapy with flaps and customized moulds

Gonzalez-Perez, Victor; Rembielak, Agata; Guinot, Jose Luis; Jaberi, Ramin; Lancellotta, Valentina; Walter, Renate; Zuchora, Anysja; Budrukkar, Ashwini; Kovács, György; Jürgenliemk-Schulz, Ina; Siebert, Frank André; Tagliaferri, Luca (Elsevier Ireland Ltd, 2022-10)

The aim of this publication is the assessment of the existing guidelines for non-melanoma skin cancer (NMSC) superficial brachytherapy (BT) and make a critical review based on the existing literature about the maximum dose ...
Automated causal inference in application to randomized controlled clinical trials

Wu, Ji Q.; Horeweg, Nanda; de Bruyn, Marco; Nout, Remi A.; Jürgenliemk-Schulz, Ina M.; Lutgens, Ludy C.H.W.; Jobsen, Jan J.; van der Steen-Banasik, Elzbieta M.; Nijman, Hans W.; Smit, Vincent T.H.B.M.; Bosse, Tjalling; Creutzberg, Carien L.; Koelzer, Viktor H. (Springer International Publishing, 2022-05)

Randomized controlled trials (RCTs) are considered the gold standard for testing causal hypotheses in the clinical domain; however, the investigation of prognostic variables of patient outcome in a hypothesized cause–effect ...
Multi-center analysis of machine-learning predicted dose parameters in brachytherapy for cervical cancer

Reijtenbagh, Dominique; Godart, Jérémy; de Leeuw, Astrid; Seppenwoolde, Yvette; Jürgenliemk-Schulz, Ina; Mens, Jan Willem; Nout, Remi; Hoogeman, Mischa (Elsevier Ireland Ltd, 2022-05)

Background and purpose: Image-guided adaptive brachytherapy (IGABT) is a key component in the treatment of cervical cancer, but the nature of the clinical workflow makes it vulnerable to suboptimal plans, as the theoretical ...
Tertiary lymphoid structures critical for prognosis in endometrial cancer patients

TransPORTEC consortium (Nature Publishing Group, 2022-03-16)

B-cells play a key role in cancer suppression, particularly when aggregated in tertiary lymphoid structures (TLS). Here, we investigate the role of B-cells and TLS in endometrial cancer (EC). Single cell RNA-sequencing of ...
Role of Brachytherapy in the Postoperative Management of Endometrial Cancer: Decision-Making Analysis among Experienced European Radiation Oncologists

Glatzer, Markus; Tanderup, Kari; Rovirosa, Angeles; Fokdal, Lars; Ordeanu, Claudia; Tagliaferri, Luca; Chargari, Cyrus; Strnad, Vratislav; Dimopoulos, Johannes Athanasios; Šegedin, Barbara; Cooper, Rachel; Nakken, Esten Søndrol; Petric, Primoz; van der Steen-Banasik, Elzbieta; Lössl, Kristina; Jürgenliemk-Schulz, Ina M.; Niehoff, Peter; Hermansson, Ruth S.; Nout, Remi A.; Putora, Paul Martin; Plasswilm, Ludwig; Tselis, Nikolaos (Multidisciplinary Digital Publishing Institute (MDPI), 2022-02-11)

BACKGROUND: There are various society-specific guidelines addressing adjuvant brachytherapy (BT) after surgery for endometrial cancer (EC). However, these recommendations are not uniform. Against this background, clinicians ...

Now showing items 10961-10980 of 40728