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UMC Repository: Recent submissions

  • Supporting the Choice for Conservative and Surgical Treatment in Female Stress Urinary Incontinence: Development and Evaluation of a Patient Decision Aid 
    Gerritse, Maria B.E.; de Vries, Marieke; The, Regina; Heesakkers, John P.F.A.; Lagro-Janssen, Antoine L.M.; Huub van der Vaart, C.; Kluivers, Kirsten B. (John Wiley & Sons Inc., 2024-11)
    Introduction: Making a treatment decision for female stress urinary incontinence (SUI) can be challenging for patients and healthcare providers. Dutch guidelines advise to counsel both pelvic floor muscle therapy and ...
  • Microstructured silk fiber scaffolds with enhanced stretchability 
    Viola, Martina; Cedillo-Servin, Gerardo; van Genderen, Anne Metje; Imhof, Isabelle; Vena, Paula; Mihajlovic, Marko; Piluso, Susanna; Malda, Jos; Vermonden, Tina; Castilho, Miguel (Royal Society of Chemistry, 2024-10-08)
    Despite extensive research, current methods for creating three-dimensional (3D) silk fibroin (SF) scaffolds lack control over molecular rearrangement, particularly in the formation of β-sheet nanocrystals that severely ...
  • Postoperative respiratory difficulties following primary cleft palate repair in infants with Robin sequence versus isolated cleft palate: A retrospective study 
    van de Velde, Shirley; Smit, Merel M.; Logjes, Bob; Martin, Enrico; Haasnoot, Maartje; Mink van der Molen, AB; Paes, Emma (Churchill Livingstone, 2024-12)
    The study aimed to: (1) compare the occurrence of postoperative respiratory difficulties (PRD) following primary cleft palate repair (CPR) in infants with an isolated cleft palate (iCP) and infants with Robin sequence (RS), ...
  • Three-Dimensional Heart Modeling of Hypertrophic Obstructive Cardiomyopathy for In Situ Patient-Specific Simulation to Optimize Septal Myectomy 
    Smits, Karin C; Speekenbrink, Ron G H; Hekman, Edsko E G; Koenrades, Maaike A; Heeringa, Tijn J P; Arens, Jutta; Halfwerk, Frank R (Lippincott Williams & Wilkins, 2024-09-02)
    OBJECTIVE: Hypertrophic obstructive cardiomyopathy (HOCM) develops in at least 1 out of 715 young adults. Patients who are refractory to medical therapy qualify for septal myectomy. Due to anatomy, serious complications ...
  • Extra-abdominal and intra-abdominal FET::CREM fusion mesenchymal neoplasms: comparative clinicopathological study of 9 new cases further supporting a distinct potentially aggressive sarcoma and report of novel sites 
    Agaimy, Abbas; Blakely, Morgan; Breimer, Gerben E; Hölsken, Annett; Koppes, Sjors A; Meidenbauer, Norbert; Rijken, Johannes A; Schad, Arno; Simon, Adrian G; Stoehr, Robert; Bishop, Justin A; Din, Nasir Ud (Springer-Verlag, 2024-12)
    With the wide use of RNA sequencing technologies, the family of FET::CREB fusion mesenchymal neoplasms has expanded rapidly to include potentially aggressive neoplasms, not fitting any well established WHO entity. Recently, ...
  • Healthcare Professionals' Perspectives on Post-Diagnostic Care for People with Vascular Cognitive Impairment: When Help Is Needed in a "No-Man's Land" 
    van de Schraaf, Sara A J; Rhodius-Meester, Hanneke F M; Rijnsent, Lindsey M; Natawidjaja, Meyrina D; van den Berg, Esther; Wolters, Frank J; Visser-Meily, J M Anne; Biessels, Geert Jan; de Vugt, Marjolein; Muller, Majon; Hertogh, Cees M P M; Sizoo, Eefje M (2024)
    BACKGROUND: Post-diagnostic care for people with vascular cognitive impairment (VCI) typically involves multiple professions and disjointed care pathways not specifically designed to aid VCI needs. OBJECTIVE: Exploring ...
  • Digital consults in heart failure care: a randomized controlled trial 
    Man, Jelle P.; Koole, Maarten A.C.; Meregalli, Paola G.; Handoko, M. Louis; Stienen, Susan; de Lange, Frederik J.; Winter, Michiel M.; Schijven, Marlies P.; Kok, Wouter E.M.; Kuipers, Dorianne I.; van der Harst, Pim; Asselbergs, Folkert W.; Zwinderman, Aeilko H.; Dijkgraaf, Marcel G.W.; Chamuleau, Steven A.J.; Schuuring, Mark J. (Nature Research, 2024-10)
    Guideline-directed medical therapy (GDMT) has clear benefits on morbidity and mortality in patients with heart failure; however, GDMT use remains low. In the multicenter, open-label, investigator-initiated ADMINISTER trial, ...
  • Initial management of newly diagnosed WHO grade 2–3 adult meningioma following surgery: results from the Dutch Brain Tumour Registry (2016–2021) 
    Ho, Vincent K.Y.; Anten, Monique M.; Garst, Anniek; Bos, Eelke M.; Snijders, Tom J.; Eekers, Daniëlle B.P.; Seute, Tatjana; the Dutch Brain Tumour Registry (DBTR) and the Dutch Society for Neuro-Oncology (LWNO) (Kluwer Academic Publishers, 2024-10)
    Purpose: Meningiomas classified as grade 2–3 according to the World Health Organisation (WHO) require combined surgery and in most cases radiotherapy (RT). Their initial management was evaluated using the Dutch Brain Tumour ...
  • The genetic landscape of neuro-related proteins in human plasma 
    Repetto, Linda; Chen, Jiantao; Yang, Zhijian; Zhai, Ranran; Timmers, Paul R.H.J.; Feng, Xiao; Li, Ting; Yao, Yue; Maslov, Denis; Timoshchuk, Anna; Tu, Fengyu; Twait, Emma L.; May-Wilson, Sebastian; Muckian, Marisa D.; Prins, Bram P.; Png, Grace; Kooperberg, Charles; Johansson, Åsa; Hillary, Robert F.; Wheeler, Eleanor; Pan, Lu; He, Yazhou; Klasson, Sofia; Ahmad, Shahzad; Peters, James E.; Gilly, Arthur; Karaleftheri, Maria; Tsafantakis, Emmanouil; Haessler, Jeffrey; Gyllensten, Ulf; Harris, Sarah E.; Wareham, Nicholas J.; Göteson, Andreas; Lagging, Cecilia; Ikram, Mohammad Arfan; van Duijn, Cornelia M.; Jern, Christina; Landén, Mikael; Langenberg, Claudia; Deary, Ian J.; Marioni, Riccardo E.; Enroth, Stefan; Reiner, Alexander P.; Dedoussis, George; Zeggini, Eleftheria; Sharapov, Sodbo; Aulchenko, Yurii S.; Butterworth, Adam S.; Mälarstig, Anders; Wilson, James F.; Navarro, Pau; Shen, Xia (Nature Publishing Group, 2024-11)
    Understanding the genetic basis of neuro-related proteins is essential for dissecting the molecular basis of human behavioural traits and the disease aetiology of neuropsychiatric disorders. Here the SCALLOP Consortium ...
  • Consensus definition and diagnostic criteria for neonatal encephalopathy—study protocol for a real-time modified delphi study 
    Branagan, Aoife; Hurley, Tim; Quirke, Fiona; Devane, Declan; Taneri, Petek E.; Badawi, Nadia; Sinha, Bharati; Bearer, Cynthia; Bloomfield, Frank H.; Bonifacio, Sonia L.; Boylan, Geraldine; Campbell, Suzann K.; Chalak, Lina; D’Alton, Mary; deVries, Linda S.; El Dib, Mohamed; Ferriero, Donna M.; Gale, Chris; Gressens, Pierre; Gunn, Alistair J.; Kay, Sarah; Maeso, Beccy; Mulkey, Sarah B.; Murray, Deirdre M.; Nelson, Karin B.; Nesterenko, Tetyana H.; Pilon, Betsy; Robertson, Nicola J.; Walker, Karen; Wusthoff, Courtney J.; Molloy, Eleanor J.; Steering Group for DEFiNE (Definition of Neonatal Encephalopathy) (Lippincott Williams & Wilkins, 2025-01)
    Background: ‘Neonatal encephalopathy’ (NE) describes a group of conditions in term infants presenting in the earliest days after birth with disturbed neurological function of cerebral origin. NE is aetiologically heterogenous; ...
  • Is Psychosocial Health a Neglected Modifier of the Link Between Cerebral Small Vessel Disease and Dementia? 
    Singh, Sanjula D.; Senff, Jasper R.; Romero, Jose Rafael (Lippincott Williams & Wilkins, 2024-10)
  • Refining Treatment Planning in STereotactic Arrhythmia Radioablation: Benchmark Results and Consensus Statement From the STOPSTORM.eu Consortium 
    Trojani, Valeria; Grehn, Melanie; Botti, Andrea; Balgobind, Brian; Savini, Alessandro; Boda-Heggemann, Judit; Miszczyk, Marcin; Elicin, Olgun; Krug, David; Andratschke, Nicolaus; Schmidhalter, Daniel; van Elmpt, Wouter; Bogowicz, Marta; de Areba Iglesias, Javier; Dolla, Lukasz; Ehrbar, Stefanie; Fernandez-Velilla, Enric; Fleckenstein, Jens; Granero, Domingo; Henzen, Dominik; Hurkmans, Coen; Kluge, Anne; Knybel, Lukas; Loopeker, Sandy; Mirandola, Alfredo; Richetto, Veronica; Sicignano, Gianluisa; Vallet, Veronique; van Asselen, Bram; Worm, Esben; Pruvot, Etienne; Verhoeff, Joost; Fast, Martin; Iori, Mauro; Blanck, Oliver (Elsevier, 2025-01-01)
    PURPOSE: STereotactic Arrhythmia Radioablation (STAR) showed promising results in patients with refractory ventricular tachycardia. However, clinical data are scarce and heterogeneous. The STOPSTORM.eu consortium was ...
  • Clusters of Parental Socioeconomic Status in Early Childhood and Inherited Risk for Cerebrovascular Disease Until Mid-life - Northern Finland Birth Cohort 1966 
    Hyytiäinen, Veronika; Ala-Mursula, Leena; Oura, Petteri; Paananen, Markus; Karhunen, Ville; Rusanen, Harri; Geerlings, Mirjam I; Miettunen, Jouko; Rissanen, Ina (SAGE Publications Ltd, 2025-01)
    Background and Aims: The incidence of cerebrovascular disease (CVD) is rising among young adults (< 55 years). The risk for CVD starts to form in early childhood and is comprised of genetic and environmental risk factors. ...
  • Continuation versus Interruption of Oral Anticoagulation during TAVI 
    van Ginkel, Dirk Jan; Bor, Willem L; Aarts, Hugo M; Dubois, Christophe; De Backer, Ole; Rooijakkers, Maxim J P; Rosseel, Liesbeth; Veenstra, Leo; van der Kley, Frank; van Bergeijk, Kees H; Van Mieghem, Nicolas M; Agostoni, Pierfrancesco; Voskuil, Michiel; Schotborgh, Carl E; IJsselmuiden, Alexander J J; Van Der Heyden, Jan A S; Hermanides, Renicus S; Barbato, Emanuele; Mylotte, Darren; Fabris, Enrico; Frambach, Peter; Dujardin, Karl; Ferdinande, Bert; Peper, Joyce; Rensing, Benno J W M; Timmers, Leo; Swaans, Martin J; Brouwer, Jorn; Nijenhuis, Vincent J; Overduin, Daniel C; Adriaenssens, Tom; Kobari, Yusuke; Vriesendorp, Pieter A; Montero-Cabezas, Jose M; El Jattari, Hicham; Halim, Jonathan; Van den Branden, Ben J L; Leonora, Remigio; Vanderheyden, Marc; Lauterbach, Michael; Wykrzykowska, Joanna J; van 't Hof, Arnoud W J; van Royen, Niels; Tijssen, Jan G P; Delewi, Ronak; Ten Berg, Jurriën M; POPular PAUSE TAVI Investigators. (Massachussetts Medical Society, 2025-01-30)
    BACKGROUND: One third of patients undergoing transcatheter aortic-valve implantation (TAVI) have an indication for oral anticoagulation owing to concomitant diseases. Interruption of oral anticoagulation during TAVI may ...
  • MYB immunohistochemistry as a predictor of MYB::NFIB fusion in the diagnosis of adenoid cystic carcinoma of the head and neck 
    Klein Nulent, Thomas J W; van Es, Robert J J; Breimer, Gerben E; Valstar, Matthijs H; Smit, Laura A; Speksnijder, Caroline M; de Bree, Remco; Willems, Stefan M (Elsevier, 2024-12)
    OBJECTIVES: Diagnosing adenoid cystic carcinoma (AdCC) is challenging due to histopathological variability and similarities with other tumors. In AdCC pathogenesis, the cellular myeloblastosis gene (c-MYB) often exhibits ...
  • Counselling for patients with a temporomandibular disorder: A scoping review and concept analysis 
    van der Meer, Hedwig A; van der Wal, Annemarie C; van Hinte, Gerben; Speksnijder, Caroline M (Wiley-Blackwell, 2024-11)
    BACKGROUND: An integral component of comprehensive temporomandibular disorder (TMD) treatment involves what is commonly referred to in literature as patient counselling or patient education. Despite its importance, a clear ...
  • The evolving genetic landscape of telomere biology disorder dyskeratosis congenita 
    Tummala, Hemanth; Walne, Amanda J.; Badat, Mohsin; Patel, Manthan; Walne, Abigail M.; Alnajar, Jenna; Chow, Chi Ching; Albursan, Ibtehal; Frost, Jennifer M.; Ballard, David; Killick, Sally; Szitányi, Peter; Kelly, Anne M.; Raghavan, Manoj; Powell, Corrina; Raymakers, Reinier; Todd, Tony; Mantadakis, Elpis; Polychronopoulou, Sophia; Pontikos, Nikolas; Liao, Tianyi; Madapura, Pradeep; Hossain, Upal; Vulliamy, Tom; Dokal, Inderjeet (Springer Science and Business Media Deutschland GmbH, 2024-10-14)
    Dyskeratosis congenita (DC) is a rare inherited bone marrow failure syndrome, caused by genetic mutations that principally affect telomere biology. Approximately 35% of cases remain uncharacterised at the genetic level. ...
  • The rise of endovascular repair for abdominal, thoracoabdominal, and thoracic aortic aneurysms 
    Conroy, Patrick D.; Rastogi, Vinamr; Yadavalli, Sai Divya; Solomon, Yoel; Romijn, Anne Sophie; Dansey, Kirsten; Verhagen, Hence J.M.; Giles, Kristina A.; Lombardi, Joseph V.; Schermerhorn, Marc L. (Mosby Inc., 2025-01)
    Background: Given changes in intervention guidelines and the growing popularity of endovascular treatment for aortic aneurysms, we examined the trends in admissions and repairs of abdominal aortic aneurysms (AAAs), ...
  • Seeking clinical consensus on risk assessment in anatomical infravesical obstruction of boys – A Delphi study 
    Leerssen, Eeke C.M.; Lindeboom, Sanne N.S.; Chrzan, Rafal; Abbas, Tariq O.; Garvelink, Mirjam; Schroeder, Rogier P.J. (Elsevier, 2024-12)
    Introduction: Infravesical obstruction (IO) is a common urological condition in young boys. Patients may present with various signs and symptoms at different ages, with severity depending to a large extent on the degree ...
  • Diffusion MRI in prostate cancer with ultra-strong whole-body gradients 
    Molendowska, Malwina; Palombo, Marco; Foley, Kieran G.; Narahari, Krishna; Fasano, Fabrizio; Jones, Derek K.; Alexander, Daniel C.; Panagiotaki, Eleftheria; Tax, Chantal M.W. (John Wiley & Sons Inc., 2024-12)
    Diffusion-weighted MRI (dMRI) is universally recommended for the detection and classification of prostate cancer (PCa), with PI-RADS recommendations to acquire b-values of ≥1.4 ms/μm2. However, clinical dMRI suffers from ...