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UMC Repository: Recent submissions

  • Can endogenous ethylene glycol production occur in humans? A detailed investigation of adult monozygotic twin sisters 
    Ghannoum, Marc; Waters, Paula J.; Hovda, Knut Erik; Choquette, Gabrielle; Elgstøen, Katja Benedikte Prestø; Nygaard, Ilah; Rootwelt, Helge; Hickey, Dean; Yazdani, Mazyar; Bourque, Danielle K. (Informa Healthcare, 2024)
    Introduction: To the best of our knowledge, clinically significant endogenous ethylene glycol production has never been reported in humans, very seldom reported in other animals or microorganisms, and then only under rare ...
  • Aortic versus distal pressure for derivation of hyperaemic microvascular resistance: From the ILIAS registry 
    Namba, Hanae F.; Boerhout, Coen K.M.; de Jong, Elize A.M.; van de Hoef, Tim P.; Piek, Jan J.; on behalf of the ILIAS Registry investigators (Elsevier Ireland Ltd, 2025-01-01)
    Background: In patients with angina and non-obstructive coronary arteries (ANOCA), intracoronary function testing typically involves assessing the minimal microvascular resistance. This can be derived from the coronary ...
  • Examining the psychometric properties of the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 among young urban South African women 
    Hart, Claire; Draper, Catherine E.; Soepnel, Larske M.; Godongwana, Motlatso; Mabetha, Khuthala; Nyati, Lukhanyo H.; Crouch, Simone H.; Norris, Shane A. (Elsevier, 2025-01-15)
    Background: Valid, reliable, and easy-to-administer scales are crucial for identifying mental health conditions, especially in LMICs where such scales tend not to be validated. This study aims to address this gap by ...
  • Assessment of coronary endothelial dysfunction using contemporary coronary function testing 
    de Jong, Elize A.M.; Namba, Hanae F.; Boerhout, Coen K.M.; Feenstra, Rutger G.T.; Woudstra, Janneke; Vink, Caitlin E.M.; Appelman, Yolande; Beijk, Marcel A.M.; Piek, Jan J.; van de Hoef, Tim P. (Elsevier Ireland Ltd, 2025-01-01)
    Background: The established diagnosis of coronary endothelial dysfunction (CED) is through the response to low-dose acetylcholine during invasive coronary function testing (CFT). Current diagnostic criteria encompass ...
  • Food consumption by degree of food processing and risk of type 2 diabetes mellitus: a prospective cohort analysis of the European Prospective Investigation into Cancer and Nutrition (EPIC) 
    Dicken, Samuel J.; Dahm, Christina C.; Ibsen, Daniel B.; Olsen, Anja; Tjønneland, Anne; Louati-Hajji, Mariem; Cadeau, Claire; Marques, Chloé; Schulze, Matthias B.; Jannasch, Franziska; Baldassari, Ivan; Manfredi, Luca; Santucci de Magistris, Maria; Sánchez, Maria Jose; Castro-Espin, Carlota; Palacios, Daniel Rodríguez; Amiano, Pilar; Guevara, Marcela; van der Schouw, Yvonne T.; Boer, Jolanda M.A.; Verschuren, W. M.Monique; Sharp, Stephen J.; Forouhi, Nita G.; Wareham, Nicholas J.; Vamos, Eszter P.; Chang, Kiara; Vineis, Paolo; Heath, Alicia K.; Gunter, Marc J.; Nicolas, Geneviève; Weiderpass, Elisabete; Huybrechts, Inge; Batterham, Rachel L. (Elsevier, 2024-11)
    Background: It is unknown whether the association between ultra-processed food (UPF) intake and type 2 diabetes mellitus differs from other degrees of food processing. We examined the association between degree of food ...
  • Stability of Cloninger's temperament traits following a health event: Subjective and objective health status analysis from the Northern Finland Birth Cohort 1966 
    Wilén, Emmi; Rissanen, Ina; Miettunen, Jouko; Korhonen, Marko (Elsevier, 2025-02)
    Personality/temperament traits are often presumed to remain stable across various life outcomes. This longitudinal study challenges this assumption by examining changes of Cloninger's Temperament and Character Inventory ...
  • Nationwide upsurge in invasive disease in the context of longitudinal surveillance of carriage and invasive Streptococcus pyogenes 2009-2023, the Netherlands: a molecular epidemiological study 
    Rümke, Lidewij W.; Davies, Matthew A.; Vestjens, Stefan M.T.; van der Putten, Boas C.L.; Bril-Keijzers, Wendy C.M.; van Houten, Marlies A.; Rots, Nynke Y.; Wijmenga-Monsuur, Alienke J.; van der Ende, Arie; de Gier, Brechje; Vlaminckx, Bart J.M.; van Sorge, Nina M. (American Society for Microbiology, 2024-10-16)
    Since 2022, many countries have reported an upsurge in invasive group A streptococcal (iGAS) infections. We explored whether changes in Streptococcus pyogenes carriage rates or emergence of strains with potentially altered ...
  • Evaluation of AJCC Nodal Staging for Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Ductal Adenocarcinoma 
    Habib, Joseph R.; Rompen, Ingmar F.; Javed, Ammar A.; Sorrentino, Anthony M.; Riachi, Mansour E.; Cao, Wenqing; Besselink, Marc G.; Molenaar, I. Quintus; He, Jin; Wolfgang, Christopher L.; Daamen, Lois A. (Springer New York, 2024-12)
    Background: The American Joint Committee on Cancer (AJCC) eighth edition is based on pancreatic intraepithelial neoplasia-derived pancreatic ductal adenocarcinoma (PDAC), a biologically distinct entity from intraductal ...
  • Impact of COVID-19 infection on lung function and nutritional status amongst individuals with cystic fibrosis: A global cohort study 
    Semenchuk, Julie; Naito, Yumi; Charman, Susan C.; Carr, Siobhán B.; Cheng, Stephanie Y.; Marshall, Bruce C.; Faro, Albert; Elbert, Alexander; Gutierrez, Hector H.; Goss, Christopher H.; Karadag, Bulent; Burgel, Pierre Régis; Colombo, Carla; Salvatore, Marco; Padoan, Rita; Daneau, Géraldine; Harutyunyan, Satenik; Kashirskaya, Nataliya; Kirwan, Laura; Middleton, Peter G.; Ruseckaite, Rasa; de Monestrol, Isabelle; Naehrlich, Lutz; Mondejar-Lopez, Pedro; Jung, Andreas; van Rens, Jacqui; Bakkeheim, Egil; Orenti, Annalisa; Zomer-van Ommen, Domenique; da Silva-Filho, Luiz Vicente RF; Fernandes, Flavia Fonseca; Zampoli, Marco; Stephenson, Anne L.; on behalf of the Global CF Registry Collaboration (Elsevier, 2024-09)
    Background: Factors associated with severe COVID-19 infection have been identified; however, the impact of infection on longer-term outcomes is unclear. The objective of this study was to examine the impact of COVID-19 ...
  • Addressing residual risk beyond statin therapy: New targets in the management of dyslipidaemias–A report from the European Society of Cardiology Cardiovascular Round Table 
    Mach, François; Visseren, Frank L.J.; Cater, Nilo B.; Salhi, Nejoua; Soronen, Jarkko; Ray, Kausik K.; Delgado, Victoria; Jukema, J. Wouter; Laufs, Ulrich; Zamorano, Jose Luis; Ros, Emilio; Plat, Jogchum; Gesztes, Akos Gabor; Tokgozoglu, Lale; Packard, Chris; Libby, Peter (Elsevier, 2024-09)
    Cardiovascular (CV) disease is the most common cause of death in Europe. Despite proven benefits, use of lipid-lowering therapy remains suboptimal. Treatment goals are often not achieved, even in patients at high risk with ...
  • Association between self-reported functional capacity measures and postoperative myocardial injury in patients undergoing noncardiac surgeries 
    Polok, Kamil; Buse, Giovanna Lurati; Mauermann, Eckhard; Ionescu, Daniela; Fronczek, Jakub; De Hert, Stefan; Filipovic, Miodrag; Schimmer, Beatrice Beck; Van Waes, Judith; Gillmann, Hans Jörg; Schultze, Cornelia; Kotfis, Katarzyna; Howell, Simon J.; Studzińska, Dorota; Espeter, Florian; Jung-König, Mona; Larmann1, Jan; Szczeklik, Wojciech; the METREPAIR investigators (Via Medica, 2024)
    Background: Self-reported functional capacity measures have an uncertain role in the pre-operative cardiovascular risk stratification. Aim: This substudy aimed to evaluate whether self-reported metabolic equivalent (MET) ...
  • Arrhythmic mitral valve prolapse phenotype: An unsupervised machine learning analysis using a multicenter cardiac MRI registry 
    Akyea, Ralph Kwame; Figliozzi, Stefano; Lopes, Pedro M.; Bauer, Klemens B.; Moura-Ferreira, Sara; Tondi, Lara; Mushtaq, Saima; Censi, Stefano; Pavon, Anna Giulia; Bassi, Ilaria; Galian-Gay, Laura; Teske, Arco J.; Biondi, Federico; Filomena, Domenico; Stylianidis, Vasileios; Torlasco, Camilla; Muraru, Denisa; Monney, Pierre; Quattrocchi, Giuseppina; Maestrini, Viviana; Agati, Luciano; Monti, Lorenzo; Pedrotti, Patrizia; Vandenberk, Bert; Squeri, Angelo; Lombardi, Massimo; Ferreira, Antonio M.; Schwitter, Juerg; Aquaro, Giovanni Donato; Pontone, Gianluca; Chiribiri, Amedeo; Palomares, José F.Rodríguez; Yilmaz, Ali; Andreini, Daniele; Florian, Anca Rezeda; Francone, Marco; Leiner, Tim; Abecasis, João; Badano, Luigi Paolo; Bogaert, Jan; Georgiopoulos, Georgios; Masci, Pier Giorgio (Radiological Society of North America Inc., 2024-06)
    Purpose: To use unsupervised machine learning to identify phenotypic clusters with increased risk of arrhythmic mitral valve prolapse (MVP). Materials and Methods: This retrospective study included patients with MVP without ...
  • The contribution of the vascular architecture and cerebrovascular reactivity to the BOLD signal formation across cortical depth 
    Roefs, Emiel C A; Schellekens, Wouter; Báez-Yáñez, Mario G; Bhogal, Alex A; Groen, Iris I A; van Osch, Matthias J P; Siero, Jeroen C W; Petridou, Natalia (MIT Press, 2024-06-01)
    Assessment of neuronal activity using blood oxygenation level-dependent (BOLD) is confounded by how the cerebrovascular architecture modulates hemodynamic responses. To understand brain function at the laminar level, it ...
  • Human breastmilk memory T cells throughout lactation manifest activated tissue-oriented profile with prominent regulation 
    Saager, Elise S; van Stigt, Arthur H; Lerkvaleekul, Butstabong; Lutter, Lisanne; Hellinga, Anneke H; van der Wal, M Marlot; Bont, Louis J; Leusen, Jeanette Hw; Van't Land, Belinda; van Wijk, Femke; Protection against Respiratory tract infections through human Milk Analysis (PRIMA) group (American Society for Clinical Investigation, 2024-09-03)
    Breastfeeding provides important immunological benefits to the neonate, but how the different immunoactive components in breastmilk contribute to immunity remains poorly understood. Here, we characterized human breastmilk ...
  • Assessing Disease Control in Patients with Atopic Dermatitis by Using the Atopic Dermatitis Control Tool in Daily Practice 
    Chen, Rui; Loman, Laura; van der Gang, Lian F; Sloot, Manon M; de Bruin-Weller, Marjolein S; Schuttelaar, Marie L A (S. Karger AG, 2024-10-22)
    INTRODUCTION: Atopic dermatitis (AD) is a chronic inflammatory skin disease, placing a significant burden on patients' quality of life (QoL). The validated Atopic Dermatitis Control Tool (ADCT) is recommended to assess AD ...
  • Introduction of a nationwide first-trimester anomaly scan in the Dutch national screening program 
    Lust, Eline E R; Bronsgeest, Kim; Henneman, Lidewij; Crombag, Neeltje; Bilardo, Caterina M; Galjaard, Robert-Jan H; Sikkel, Esther; van der Hout, Sanne; Coumans, Audrey; Elvan-Taşpınar, Ayten; Go, Attie T J I; Galjaard, Sander; Manten, Gwendolyn T R; Pajkrt, Eva; van Leeuwen, Liesbeth; Haak, Monique C; Bekker, Mireille N (Mosby Inc., 2025-04)
    Background: A significant proportion of major fetal structural anomalies can be detected in the first trimester by ultrasound examination. However, the test performance of the first-trimester anomaly scan performed in a ...
  • Women's experiences with using patient-reported outcome and experience measures in routine perinatal care in the Netherlands: a mixed-methods study 
    Laureij, Lyzette T; Depla, Anne L; Kariman, Shariva S; Lamain-de Ruiter, Marije; Ernst-Smelt, Hiske E; Hazelzet, Jan Antonius; Franx, Arie; Bekker, Mireille N; BUZZ Project Team (BMJ Publishing Group, 2023-03-10)
    OBJECTIVES: To gain insight into the experiences of women with completing and discussing patient-reported outcome measures (PROM) and patient-reported experience measures (PREM), and tailoring their care based on their ...
  • Abatacept bij de behandeling van monogenetische en refractaire inflammatoire ziekte 
    Leavis, Helen; van den Berg, J.M.; Berghuis, D.; de Bree, G.J.; Buddingh, Emilie P.; Bulatovic-Calasan, Maja; Dalm, Virgil A.S.H.; van Hagen, P. Martin; Hamann, Dörte; Henriet, Stefanie S V; Hoppenreijs, E.P.A.H.; Jansen, Marc; Kuijpers, T.W.; Legger, GE; van Montfrans, Joris; Mulders-Manders, K.; Potjewijd, Judith; Rutgers, Abraham; Scholvinck, E.H.; van de Veerdonk, Frank L.; Vermont, C.L.; van Well, G.T.J. (2024-08)
    Abatacept is a potent anti-inflammatory drug. Its effectiveness and safety in the treatment of rheumatoid arthritis, psoriatic arthritis, and juvenile idiopathic arthritis has been well researched in randomized controlled ...
  • JAK-remmers in de behandeling van zeldzame afweerstoornissen en autoinflammatoire aandoeningen 
    Buddingh, Emilie P.; van den Berg, J. M.; Berghuis, D.; de Bree, G.J.; Bulatovic-Calasan, Maja; Dalm, Virgil A.S.H.; Van Hagen, P.M.; Hamann, Dörte; Henriet, Stefanie S V; Hoppenreijs, E.P.A.H.; Jansen, Marc; Kuijpers, T.W.; Leavis, Helen; Legger, GE; van Montfrans, Joris; Mulders-Manders, K.; Potjewijd, Judith; Rutgers, Abraham; Scholvinck, E.H.; van de Veerdonk, Frank L.; Vermont, C.L.; van Well, G.T.J. (2024-08)
    JAK inhibitors are novel, powerful anti-inflammatory agents. For patients with relatively common inflammatory conditions such as rheumatoid arthritis and ulcerative colitis, the effectiveness and safety of these agents ...
  • Novel Insights into Non-Invasive Diagnostic Techniques for Cardiac Amyloidosis: A Critical Review 
    Dicorato, Marco Maria; Basile, Paolo; Muscogiuri, Giuseppe; Carella, Maria Cristina; Naccarati, Maria Ludovica; Dentamaro, Ilaria; Guglielmo, Marco; Baggiano, Andrea; Mushtaq, Saima; Fusini, Laura; Pontone, Gianluca; Forleo, Cinzia; Ciccone, Marco Matteo; Guaricci, Andrea Igoren (MDPI AG, 2024-10)
    Cardiac amyloidosis (CA) is a cardiac storage disease caused by the progressive extracellular deposition of misfolded proteins in the myocardium. Despite the increasing interest in this pathology, it remains an underdiagnosed ...