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UMC Repository: Recent submissions

  • Long-term maternal outcomes 5 years after cesarean section in Sierra Leone: A prospective cohort study 
    Logstein, Erika; Torp, Richard; Ashley, Thomas; Kamara, Michael M.; Koroma, Alimamy P.; Dumbuya, Abu Bakarr; Suma, Musa S.; Moijue, Abdul Rahman; Westendorp, Josien; Kujabi, Monica L.; Rijken, Marcus J.; Wibe, Arne; Hagander, Lars; Leather, Andrew J.M.; Bolkan, Håkon A.; van Duinen, Alex J. (John Wiley & Sons Inc., 2025-03)
    Cesarean section (CS) is a life-saving procedure when performed for the right indication but carries substantial risks, specifically during subsequent pregnancies. The aim of this study was to evaluate obstetric outcomes ...
  • Recapitulating the adenoma–carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids 
    Mizutani, Tomohiro; Boretto, Matteo; Lim, Sangho; Drost, Jarno; González, Diego Montiel; Oka, Rurika; Geurts, Maarten H.; Begthel, Harry; Korving, Jeroen; van Es, Johan H.; van Boxtel, Ruben; Clevers, Hans (Nature Research, 2024-12)
    Carcinogenesis results from the sequential acquisition of oncogenic mutations that convert normal cells into invasive, metastasizing cancer cells. Colorectal cancer exemplifies this process through its well-described ...
  • Prognostic value of repeated peak oxygen uptake measurements in patients with a left ventricular assist device 
    Nielsen, William Herrik; Szymanski, Mariusz K.; Mirza, Kiran K.; Van Laake, Linda W.; Schmidt, Thomas; Brahmbhatt, Darshan H.; Billia, Filio; Hsu, Steven; MacGowan, Guy; Jakovljevic, Djordje G.; Agostoni, Piergiuseppe; Trombara, Filippo; Jorde, Ulrich P.; Rochlani, Yogita; Vandersmissen, Katrien; Reiss, Nils; Russell, Stuart D.; Meyns, Bart; Gustafsson, Finn (Elsevier, 2025-02)
    Background: Peak oxygen uptake (pVO2) predicts mortality in patients with heart failure on left ventricular assist device (LVAD) support. This follow-up of the PRO-VAD study examines the prognostic value of repeated pVO2 ...
  • Recurrent CLTC::SYK fusions and CSF1R mutations in juvenile xanthogranuloma of soft tissue 
    Kemps, Paul G.; Baelde, Hans J.; Vorderman, Ruben H.P.; Stelloo, Ellen; Swennenhuis, Joost F.; Szuhai, Karoly; Lamers, Meindert H.; Kenkhuis, Boyd; Al-Hussaini, Maysa; Briaire-de Bruijn, Inge H.; Lam, Suk Wai; Bovée, Judith V.M.G.; Cleven, Arjen H.G.; Verdijk, Robert M.; van Noesel, Carel J.M.; van Dijk, Marijke R.; Scheijde-Vermeulen, Marijn A.; Bruggink, Annette H.; van Laar, Jan A.M.; de Vries, Andrica C.H.; Tissing, Wim J.E.; van den Bos, Cor; von Deimling, Andreas; van Wezel, Tom; van Halteren, Astrid G.S.; Hogendoorn, Pancras C.W. (Elsevier, 2024-12-05)
    Juvenile xanthogranuloma (JXG) is a histiocytic neoplasm that usually presents in the skin. Rarely, extracutaneous localizations occur; the genetic drivers of this clinical variant of JXG remain incompletely characterized. ...
  • Knowledge, attitudes and practices around urinary tract infections of general practitioners in the Netherlands: a cross-sectional internet survey 
    Cox, Stefan Martinus Leonardus; Giorgi, Wesley; Platteel, Tamara N.; Cals, Jochen W.L.; de Bont, Eefje G.P.M. (BMJ Publishing Group, 2024-10-26)
    OBJECTIVES: Urinary tract infections (UTIs) are the most common reason for women to consult a general practitioner (GP). Current diagnostic tests are inadequate, complicating diagnosis and treatment decisions for GPs. To ...
  • Predictive modelling of the effectiveness of vaccines against COVID-19 in Bogotá: Methodological innovation involving different variants and computational optimisation efficiency 
    Espinosa, Oscar; White, Lisa; Bejarano, Valeria; Aguas, Ricardo; Rincón, Duván; Mora, Laura; Ramos, Antonio; Sanabria, Cristian; Rodríguez, Jhonathan; Barrera, Nicolás; Álvarez-Moreno, Carlos; Cortés, Jorge; Saavedra, Carlos; Robayo, Adriana; Gao, Bo; Franco, Oscar (Elsevier, 2024-11-15)
    The uncertainty associated with the future of viruses such as SARS-CoV-2 poses a challenge to public health officials because of its implications for welfare, economics and population health. In this document, we develop ...
  • Telemedicine ultrasound assessment for placenta accreta spectrum: Utility and interobserver reliability of asynchronous remote imaging review 
    Nieto-Calvache, Albaro José; Benavides-Calvache, Juan Pablo; Aryananda, Rozi; Palacios-Jaraquemada, Jose M.; Jauniaux, Eric; Fox, Karin A.; Coutinho, Conrado Milani; Adu-Bredu, Theophilus; Shih, Jin Chung; Hussein, Ahmed M.; Timor-Tritsch, Ilan E.; Bartels, Helena C.; Hamer, Jorge; Cali, Giuseppe; D'Antonio, Francesco; Nieto-Calvache, Alejandro Solo; López, Jaime Octavio; Rivera-Torres, Luisa Fernanda; Pajkrt, Eva; Rijken, Marcus J. (John Wiley & Sons Inc., 2025-03)
    OBJECTIVE: Management of patients with placenta accreta spectrum (PAS) by trained multidisciplinary teams is associated with improved outcomes. Ultrasound can predict intraoperative risks, but expert ultrasound imaging of ...
  • Knowledge gaps in diagnosing chronic polyneuropathy: Review of national guidelines 
    Wiersma, M.; van der Star, G. M.; Notermans, N. C.; van Doorn, P. A.; Vrancken, A. F.J.E.; The EXPRESS Study Consortium (Wiley-Blackwell, 2024-12)
    The prevalence of chronic polyneuropathy will increase due to the aging population, and therefore, it becomes ever so important to optimize the diagnostic process. However, it is uncertain which blood tests are required ...
  • Incidence, diagnostics, therapeutic management and outcomes of paediatric intestinal pseudo-obstruction in the Netherlands: A 20-year retrospective cohort study 
    Demirok, Aysenur; Nagelkerke, Sjoerd C.J.; Veldt, Malou; Gorter, Ramon; de Jong, Justin R.; Damen, Gerard M.; de Koning, Barbara A.E.; Meijer, Caroline; van Rheenen, Patrick F.; Wolters, Victorien M.; Benninga, Marc A.; Tabbers, Merit M. (Lippincott Williams & Wilkins, 2025-01)
    Objectives: To describe incidence, clinical course, diagnostic and therapeutic management and long-term follow-up of paediatric intestinal pseudo-obstruction (PIPO) in the Netherlands between 2000 and 2020. Methods: ...
  • Recording diagnostic conversations for communication research purposes in pediatric leukemia 
    Buursma, Petra; Schepers, Sasja A.; Kars, Marijke C.; van den Bergh, Esther M.M.; Dors, Natasja; Grootenhuis, Martha A.; Hoogerbrugge, Peter M. (Wiley-Liss Inc., 2025-01)
    Recordings of patient–doctor interactions is a recommended method in communication research. However, concerns are expressed regarding audio-recording of conversations with vulnerable patients. Our study examined experiences ...
  • Recognisable Neuroradiological Findings in Five Neurogenetic Disorders 
    Rosenblum, Jessica; Meuwissen, Marije; Jansen, Anna C; Oegema, Renske; Reddy, Nihaal; Mankad, Kshitij; Sudhakar, Sniya (Wiley-Blackwell, 2025-01)
    The rate of discovery and increased understanding of genetic causes for neurodevelopmental disorders has peaked over the past decade. It is well recognised that some genes show marked variability in neuroradiological ...
  • Amyotrophic lateral sclerosis established as a multistep process across phenotypes 
    Ziser, Laura; van Eijk, Ruben P.A.; Kiernan, Matthew C.; McRae, Allan; Henderson, Robert D.; Schultz, David; Needham, Merrilee; Mathers, Susan; McCombe, Pam; Talman, Paul; Vucic, Steve (Wiley-Blackwell, 2025-01)
    Background and purpose: Given the accepted multistep process of disease causation in amyotrophic lateral sclerosis (ALS), the present study was undertaken to determine the number of steps required for disease onset across ...
  • Holmium-166 radioembolisation dosimetry in HCC 
    Reinders, Margot T.M.; Braat, Arthur J.A.T.; van Erpecum, Karel J.; de Bruijne, Joep; Bruijnen, Rutger C.G.; Sprengers, Dave; de Man, Rob; Vegt, Erik; IJzermans, Jan N.M.; Elias, Sjoerd G.; Lam, Marnix G.E.H.; Smits, Maarten L.J. (Springer-Verlag, 2025-02)
    Purpose: To evaluate dosimetry, dose–response and dose-toxicity relationships for holmium-166 (166Ho) radioembolisation in patients with hepatocellular carcinoma (HCC). Methods: Thirty-one patients with hepatocellular ...
  • Editorial: Stem cell transplantation in autoimmune diseases (AID) 
    Schmalzing, Marc; Henes, Joerg; van Laar, Jacob M.; Sullivan, Keith M. (Frontiers Media S. A., 2023)
  • USING SELF-REGULATION ASSESSMENT TO EXPLORE ASSOCIATIONS BETWEEN SELF-REGULATION, PARTICIPATION AND HEALTH-RELATED QUALITY OF LIFE IN A REHABILITATION POPULATION 
    Mol, Tanja I.; Scholten, Eline W.M.; van Bennekom, Coen A.M.; Visser, Johanna M.A.; Reneman, Michiel F.; de Groot, Vincent; Meijer, Jan Willem G.; Smeets, Rob J.E.M.; Post, M. Marcel W.M. (Medical Journals Sweden AB, 2023-02-07)
    Objective: Self-regulation, participation and health-related quality of life are important rehabilitation outcomes. The aim of this study was to explore associations between these outcomes in a multi-diagnostic and heterogenic ...
  • Combined Statin and Glucocorticoid Therapy for the Safer Treatment of Preterm Birth 
    Kane, Andrew D.; Herrera, Emilio A.; Niu, Youguo; Camm, Emily J.; Allison, Beth J.; Tijsseling, Deodata; Lusby, Ciara; Derks, Jan B.; Brain, Kirsty L.; Bronckers, Inge M.; Cross, Christine M.; Berends, Lindsey; Giussani, Dino A. (Lippincott Williams & Wilkins, 2023-04-01)
    Background: Prematurity is strongly associated with poor respiratory function in the neonate. Rescue therapies include treatment with glucocorticoids due to their anti-inflammatory and maturational effects on the developing ...
  • Ustekinumab Trough Concentrations Are Associated with Biochemical Outcomes in Patients with Crohn’s Disease 
    Straatmijer, Tessa; Biemans, Vince B.C.; Moes, Dirk Jan A.R.; Hoentjen, Frank; ter Heine, Rob; Maljaars, P. W.Jeroen; Theeuwen, Rosaline; Pierik, Marieke; Duijvestein, Marjolijn; van der Meulen-de Jong, Andrea E.; the Dutch Initiative on Crohn’s and Colitis (ICC) (Springer New York, 2023-06)
    Objective: It is unknown whether ustekinumab (UST) levels can predict clinical outcomes in Crohn’s disease (CD) patients. We assessed the exposure–response relationship of UST trough concentrations with biochemical outcomes ...
  • Social jet lag and (changes in) glycemic and metabolic control in people with type 2 diabetes 
    Bouman, Emma J.; Beulens, Joline W.J.; den Braver, Nicolette R.; Blom, Marieke T.; Remmelzwaal, Sharon; Elders, Petra J.M.; Rutters, Femke (John Wiley & Sons Inc., 2023-04)
    Objective: Social jet lag, i.e., the discordance among social and biological rhythms, is associated with poor metabolic control. This study aimed to assess cross-sectional and longitudinal associations among social jet lag ...
  • Medical interventions for traumatic hyphema 
    Woreta, Fasika A.; Lindsley, Kristina B.; Gharaibeh, Almutez; Ng, Sueko M.; Scherer, Roberta W.; Goldberg, Morton F. (John Wiley & Sons Inc., 2023-03-13)
    Background: Traumatic hyphema is the entry of blood into the anterior chamber, the space between the cornea and iris, following significant injury to the eye. Hyphema may be associated with significant complications that ...
  • Importance of Systematic Diagnostic Testing in Idiopathic Ventricular Fibrillation: Results From the Dutch iVF Registry 
    Groeneveld, Sanne A.; Verheul, Lisa M.; van der Ree, Martijn H.; Mulder, Bart A.; Scholten, Marcoen F.; Alings, Marco; van der Voort, Pepijn; Bootsma, Marianne; Evertz, Reinder; Balt, Jippe C.; Yap, Sing Chien; Doevendans, Pieter A.F.M.; Postema, Pieter G.; Wilde, Arthur A.M.; Volders, Paul G.A.; Hassink, Rutger J. (Elsevier, 2023-03)
    Background: Idiopathic ventricular fibrillation (iVF) is a diagnosis of exclusion. Systematic diagnostic testing is important to exclude alternative causes for VF. The early use of “high yield” testing, including cardiac ...