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UMC Repository: Recent submissions

  • Cardiovascular Risk Estimation Based on Country-of-Birth- and Country-of-Residence-Specific Scores among Migrants in the Netherlands: The HELIUS Study 
    Osei-Yeboah, James; Moll van Charante, Eric P.; Kengne, Andre Pascal; Owusu-Dabo, Ellis; van den Born, Bert Jan H.; Galenkamp-van der Ploeg, Henrike; Chilunga, Felix P.; Boateng, Daniel; Motazedi, Ehsan; Agyemang, Charles (Multidisciplinary Digital Publishing Institute (MDPI), 2023-03)
    Background: Regional and country-specific cardiovascular risk algorithms have been developed to improve CVD risk prediction. But it is unclear whether migrants’ country-of-residence or country-of-birth algorithms agree in ...
  • In Vitro Testing and Clinical Handling of a Novel Implant Positioning Technology for Proximal Humeral Plating 
    Windolf, Markus; Knierzinger, Dominik; Nijs, Stefaan; Sermon, An; Blauth, Michael; Richards, Robert Geoff; Buschbaum, Jan (Multidisciplinary Digital Publishing Institute (MDPI), 2023-03)
    Background and Objectives: Fractures of the proximal humerus are common, particularly in elderly populations. Anatomical locking plates target stabilization with a multitude of screws spanning into the humeral head. Sound ...
  • Best management of patients with an acute sore throat–a critical analysis of current evidence and a consensus of experts from different countries and traditions 
    Gunnarsson, Ronny K.; Ebell, Mark; Centor, Robert; Little, Paul; Verheij, Theo; Lindbæk, Morten; Sundvall, Pär Daniel (Taylor and Francis Ltd., 2023)
    Background: There is a very large body of publications discussing the management of patients with an acute sore throat. Advocates for a restrictive antibiotic policy and advocates for a more liberal use of antibiotics ...
  • Identification of Novel Associations and Localization of Signals in Idiopathic Inflammatory Myopathies Using Genome-Wide Imputation 
    Rothwell, Simon; Amos, Christopher I.; Miller, Frederick W.; Rider, Lisa G.; Lundberg, Ingrid E.; Gregersen, Peter K.; Vencovsky, Jiri; McHugh, Neil; Limaye, Vidya; Selva-O'Callaghan, Albert; Hanna, Michael G.; Machado, Pedro M.; Pachman, Lauren M.; Reed, Ann M.; Molberg, Øyvind; Benveniste, Olivier; Mathiesen, Pernille; Radstake, Timothy; Doria, Andrea; De Bleecker, Jan L.; De Paepe, Boel; Maurer, Britta; Ollier, William E.; Padyukov, Leonid; O'Hanlon, Terrance P.; Lee, Annette; Wedderburn, Lucy R.; Chinoy, Hector; Lamb, Janine A.; the Myositis Genetics Consortium (John Wiley & Sons Inc., 2023-06)
    Objective: The idiopathic inflammatory myopathies (IIMs) are heterogeneous diseases thought to be initiated by immune activation in genetically predisposed individuals. We imputed variants from the ImmunoChip array using ...
  • ERN ReCONNET points to consider for treating patients living with autoimmune rheumatic diseases with antiviral therapies and anti-SARS-CoV-2 antibody products 
    Talarico, Rosaria R.; Ramirez, G. A.; Barreira, S. C.; Cardamone, C.; Triggianese, P.; Aguilera, S.; Andersen, J.; Avcin, T.; Benistan, K.; Bertsias, G.; Bortoluzzi, A.; Bouillot, C.; Bulina, I.; Burmester, G. R.; Callens, S.; Carreira, P. E.; Cervera, R.; Cutolo, M.; Damian, L.; Torre, E. Della; Faria, R.; Fonseca, J. E.; Galetti, I.; Hachulla, E.; Iaccarino, L.; Jacobsen, S.; Khmelinskii, N.; Limper, M.; Marinello, D.; Meyer, A.; Moroncini, G.; Nagy, G.; Olesinska, M.; Pamfil, C.; Pileckyte, M.; Pistello, M.; Rednic, S.; Richez, C.; Romão, V. C.; Schneider, M.; Sciascia, S.; Scirè, C. A.; Simonini, G.; Smith, V.; Sulli, A.; Tani, C.; Tas, S. W.; Tincani, A.; Vonk, M. C.; Tektonidou, M.; Mosca, M. (Clinical and Experimental Rheumatology S.A.S., 2023-03)
    Recent studies have shown that people who are immunocompromised may inadvertently play a role in spurring the mutations of the virus that create new variants. This is because some immunocompromised individuals remain at ...
  • Natural Language Processing Markers for Psychosis and Other Psychiatric Disorders: Emerging Themes and Research Agenda From a Cross-Linguistic Workshop 
    Corona Hernández, Hugo; Corcoran, Cheryl; Achim, Amélie M.; De Boer, Janna N.; Boerma, Tessel; Brederoo, Sanne G.; Cecchi, Guillermo A.; Ciampelli, Silvia; Elvevåg, Brita; Fusaroli, Riccardo; Giordano, Silvia; Hauglid, Mathias; Van Hessen, Arjan; Hinzen, Wolfram; Homan, Philipp; De Kloet, Sybren F.; Koops, Sanne; Kuperberg, Gina R.; Maheshwari, Kritika; Mota, Natalia B.; Parola, Alberto; Rocca, Roberta; Sommer, Iris E.C.; Truong, Khiet; Voppel, Alban E.; Van Vugt, Marieke; Wijnen, Frank; Palaniyappan, Lena (Oxford University Press, 2023-03-01)
    This workshop summary on natural language processing (NLP) markers for psychosis and other psychiatric disorders presents some of the clinical and research issues that NLP markers might address and some of the activities ...
  • Fatale sepsis als gevolg van een hondenbeet 
    Rutten, Karlijn; Loots, Feike; Venekamp, Roderick; Godschalk, Peggy; van Haaften, Laura (Bohn Stafleu van Loghum, 2023-04)
    Vroegtijdige herkenning van sepsis in de eerste lijn vormt een uitdaging, maar is cruciaal om morbiditeit en complicaties te voorkomen. Een zeldzame oorzaak van sepsis is een infectie met Capnocytophaga canimorsus als ...
  • Genomic characterization of DICER1-associated neoplasms uncovers molecular classes 
    Kommoss, Felix K.F.; Chong, Anne Sophie; Chong, Anne Laure; Pfaff, Elke; Jones, David T.W.; Hiemcke-Jiwa, Laura S.; Kester, Lennart A.; Flucke, Uta; Gessler, Manfred; Schrimpf, Daniel; Sahm, Felix; Clarke, Blaise A.; Stewart, Colin J.R.; Wang, Yemin; Gilks, C. Blake; Kommoss, Friedrich; Huntsman, David G.; Schüller, Ulrich; Koelsche, Christian; Glenn McCluggage, W.; von Deimling, Andreas; Foulkes, William D. (Nature Publishing Group, 2023-12)
    DICER1 syndrome is a tumor predisposition syndrome that is associated with up to 30 different neoplastic lesions, usually affecting children and adolescents. Here we identify a group of mesenchymal tumors which is highly ...
  • Platelet RNA sequencing for cancer screening in patients with unprovoked venous thromboembolism: a prospective cohort study 
    Mulder, Frits I.; Kraaijpoel, Noémie; Carrier, Marc; Guman, Noori A.; Jara-Palomares, Luis; Di Nisio, Marcello; Ageno, Walter; Beyer-Westendorf, Jan; Klok, Frederikus A.; Vanassche, Thomas; Otten, Hans Martin B.; Cosmi, Benilde; Wolde, Marije ten; In ‘t Veld, Sjors G.J.G.; Post, Edward; Ramaker, Jip; Zwaan, Kenn; Peters, Mike; Delluc, Aurélien; Kamphuisen, Pieter W.; Sanchez-Lopez, Veronica; Porreca, Ettore; Bossuyt, Patrick M.M.; Büller, Harry R.; Wurdinger, Thomas; Best, Myron G.; van Es, Nick (Wiley-Blackwell, 2023-04)
    Background: Platelet RNA sequencing has been shown to accurately detect cancer in previous studies. Objectives: To compare the diagnostic accuracy of platelet RNA sequencing with standard-of-care limited cancer screening ...
  • Using the embryo-uterus statistical model to predict pregnancy chances by using cleavage stage morphokinetics and female age: two centre-specific prediction models and mutual validation 
    van Marion, Eva S.; Baart, Esther B.; Santos, Margarida; van Duijn, Linette; van Santbrink, Evert J.P.; Steegers-Theunissen, Régine P.M.; Laven, Joop S.E.; Eijkemans, Marinus J.C. (BioMed Central, 2023-03-27)
    Background: The predictive capability of time-lapse monitoring (TLM) selection algorithms is influenced by patient characteristics, type and quality of data included in the analysis and the used statistical methods. Previous ...
  • Higher levels of response on clinical atopic dermatitis severity measures are associated with meaningful improvements in patient-reported symptom and quality of life measures: Integrated analysis of three Upadacitinib phase 3 trials 
    Reich, K.; de Bruin-Weller, M. S.; Deleuran, M.; Calimlim, B. M.; Chen, N.; Hu, X.; Tenorio, A. R.; Silverberg, J. I. (Wiley-Blackwell, 2023-08)
    Background: It is not fully understood how different degrees of improvements in atopic dermatitis (AD) clinical outcome measures translate to improvements in patient-reported outcome (PRO) measures, such as those assessing ...
  • Safety and Feasibility of Interventional Hybrid Fluoroscopy and Nuclear Imaging in the Work-up Procedure of Hepatic Radioembolization 
    Dietze, Martijn M.A.; Meddens, Marjolein B.M.; van Rooij, Rob; Braat, Arthur J.A.T.; de Keizer, Bart; Bruijnen, Rutger C.G.; Lam, Marnix G.E.H.; Smits, Maarten L.J.; de Jong, Hugo W.A.M. (Radiological Society of North America Inc., 2024-11-01)
    Purpose: To evaluate the safety and feasibility of a novel hybrid nuclear and fluoroscopy C-arm scanner to be used during the work-up procedure of hepatic radioembolization. Materials and Methods: In this prospective ...
  • Personalized bioceramic grafts for craniomaxillofacial bone regeneration 
    de Carvalho, Ana Beatriz G.; Rahimnejad, Maedeh; Oliveira, Rodrigo L.M.S.; Sikder, Prabaha; Saavedra, Guilherme S.F.A.; Bhaduri, Sarit B.; Gawlitta, Debby; Malda, Jos; Kaigler, Darnell; Trichês, Eliandra S.; Bottino, Marco C. (Springer Nature, 2024-10-31)
    The reconstruction of craniomaxillofacial bone defects remains clinically challenging. To date, autogenous grafts are considered the gold standard but present critical drawbacks. These shortcomings have driven recent ...
  • Comparison of cognitive behaviour therapy versus activity management, both delivered remotely, to treat paediatric chronic fatigue syndrome/myalgic encephalomyelitis: the UK FITNET-NHS RCT 
    Crawley, Esther; Anderson, Emma; Cochrane, Madeleine; Shirkey, Beverly A.; Parslow, Roxanne; Hollingworth, William; Mills, Nicola; Gaunt, Daisy; Treneman-Evans, Georgia; Rai, Manmita; Macleod, John; Kessler, David; Pitts, Kieren; Cooper, Serena; Loades, Maria; Annaw, Ammar; Stallard, Paul; Knoop, Hans; Van de Putte, Elise; Nijhof, Sanne; Bleijenberg, Gijs; Metcalfe, Chris (NIHR Journals Library, 2024-10-01)
    Methods: Participants: Adolescents aged 11–17 years, diagnosed with myalgic encephalomyelitis/chronic fatigue syndrome and with no local specialist treatment centre, were referred to a specialist service in South West ...
  • Living systematic review and comprehensive network meta-analysis of ALS clinical trials: study protocol 
    Van Loon, Floris T.; Seitidis, Georgios; Mavridis, Dimitris; van Unnik, Jordi W.J.; Weemering, Daphne N.; van den Berg, Leonard H.; Bethani, Ilianna; Nikolakopoulos, Stavros; van Eijk, Ruben P.A. (BMJ Publishing Group, 2024-11-01)
    INTRODUCTION: Amyotrophic lateral sclerosis (ALS) is a fatal neurogenerative disease with no effective treatment to date. Despite numerous clinical trials, the majority of studies have been futile in their effort to ...
  • Shared decision making in primary malignant bone tumour surgery around the knee in children and young adults: protocol for a prospective study 
    Blom, Kiki J.; Bekkering, Willem P.; Fiocco, Marta; van de Sande, Michiel Aj; Schreuder, Hendrik Wb; van der Heijden, Lizz; Jutte, Paul C.; Haveman, Lianne M.; Merks, Johannes Hm; Bramer, Jos Am (BioMed Central, 2024-11-02)
    BACKGROUND: Children and young adults needing surgery for a primary malignant bone tumour around the knee face a difficult, life-changing decision. A previous study showed that this population wants to be involved more in ...
  • Riboflavin transporter deficiency, the search for the undiagnosed: a retrospective data mining study 
    Jaeger, B.; Hoytema van Konijnenburg, E.; Groenveld, M. A.; Langeveld, M.; Wolf, N. I.; Bosch, A. M. (BioMed Central, 2024-11-01)
    BACKGROUND: Riboflavin transporter deficiency (RTD) is an inborn error of riboflavin transport causing progressive neurological symptoms if left untreated. While infants with symptomatic RTD rapidly deteriorate, presentation ...
  • Examining Macro-Level Barriers and Facilitators to Scaling Up Integrated Care from a Complexity Perspective: A Multi-Case Study of Cambodia, Slovenia, and Belgium 
    Martens, Monika; Chham, Savina; Zavrnik, Črt; Danhieux, Katrien; Wouters, Edwin; Chhim, Srean; Susič, Antonija Poplas; Ketiš, Zalika Klemenc; Ir, Por; Remmen, Roy; Klipstein-Grobusch, Kerstin; Van Damme, Wim; Ku, Grace Marie; Van Olmen, Josefien (Igitur, Utrecht Publishing and Archiving Services, 2024-11-12)
    Introduction: The \‘Scale-Up diaBetes and hYpertension care\’ (SCUBY) project provides evidence on scaling-up integrated care (IC) in Cambodia, Slovenia, and Belgium. This paper examines macro-level barriers and facilitators ...
  • Lessons Learnt from HIV and Noncommunicable Disease Healthcare Integration in Sub-Saharan Africa 
    van der Mannen, Jessica S.; Heine, Martin; Lalla-Edward, Samanta T.; Ojji, Dike B.; Mocumbi, Ana O.; Klipstein-Grobusch, Kerstin (Elsevier Science & Technology, 2024-11-12)
    In sub-Saharan Africa (SSA), a rising burden of noncommunicable diseases (NCDs) coexists with a persistent high burden of human immunodeficiency virus (HIV). Integrating care for chronic conditions is potentially beneficial, ...
  • Morphology of atrial myocardium in human pulmonary veins: A postmortem analysis in patients with and without atrial fibrillation 
    Hassink, Rutger J.; Aretz, H. Thomas; Ruskin, Jeremy; Keane, David (Elsevier, 2003-09-17)
    OBJECTIVES: We report an in-depth postmortem morphologic analysis of atrial myocardium in human pulmonary veins (PVs) from patients with and without atrial fibrillation (AF). BACKGROUND: Electrophysiologic studies established ...