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Reduced mammillary body volume in individuals with a schizophrenia diagnosis: an analysis of the COBRE data set

Milczarek, Michal M; Gilani, Syed Irtiza A; Lequin, Maarten H; Vann, Seralynne D (2023-08-01)

While the frontal cortices and medial temporal lobe are well associated with schizophrenia, the involvement of wider limbic areas is less clear. The mammillary bodies are important for both complex memory formation and ...
Carfilzomib, lenalidomide and dexamethasone followed by a second ASCT is an effective strategy in first relapse multiple myeloma: a study on behalf of the Chronic malignancies working party of the EBMT

Tilmont, Rémi; Yakoub-Agha, Ibrahim; Eikema, Diderik-Jan; Zinger, Nienke; Haenel, Mathias; Schaap, Nicolaas; Arroyo, Concepcion Herrera; Schuermans, Christine; Besemer, Britta; Engelhardt, Monika; Kuball, Jürgen; Michieli, Mariagrazia; Schub, Natalie; Wilson, Keith M O; Bourhis, Jean Henri; Mateos, Maria Victoria; Rabin, Neil; Jost, Edgar; Kröger, Nicolaus; Moraleda, José M; Za, Tommaso; Hayden, Patrick J; Beksac, Meral; Mclornan, Donal; Schönland, Stefan; Manier, Salomon (Springer Nature, 2023-11)

In the setting of a first relapse of multiple myeloma (MM), a second autologous stem cell transplant (ASCT) following carfilzomib-lenalidomide-dexamethasone (KRd) is an option, although there is scarce data concerning this ...
A gap-filling, regenerative implant for open-wedge osteotomy

Rikkers, Margot; Nguyen, H. Chien; Golafshan, Nasim; de Ruijter, Mylène; Levato, Riccardo; Vonk, Lucienne A.; van Egmond, Nienke; Castilho, Miguel; Custers, Roel J.H.; Malda, Jos (2023-12)

Introduction: In patients suffering from unilateral osteoarthritis in the knee, an osteotomy can provide symptomatic relief and postpone the need for replacement of the joint. Nevertheless, open-wedge osteotomies (OWOs) ...
Spatial-Selective Volumetric 4D Printing and Single-Photon Grafting of Biomolecules within Centimeter-Scale Hydrogels via Tomographic Manufacturing

Falandt, Marc; Bernal, Paulina Nuñez; Dudaryeva, Oksana; Florczak, Sammy; Größbacher, Gabriel; Schweiger, Matthias; Longoni, Alessia; Greant, Coralie; Assunção, Marisa; Nijssen, Olaf; van Vlierberghe, Sandra; Malda, Jos; Vermonden, Tina; Levato, Riccardo (Wiley-Blackwell, 2023-08-11)

Conventional additive manufacturing and biofabrication techniques are unable to edit the chemicophysical properties of the printed object postprinting. Herein, a new approach is presented, leveraging light-based volumetric ...
Load-induced fluid pressurisation in hydrogel systems before and after reinforcement by melt-electrowritten fibrous meshes

Moo, Eng Kuan; Ebrahimi, Mohammadhossein; Hrynevich, Andrei; de Ruijter, Mylène; Castilho, Miguel; Malda, Jos; Korhonen, Rami K. (Elsevier, 2023-07)

Fluid pressure develops transiently within mechanically-loaded, cell-embedding hydrogels, but its magnitude depends on the intrinsic material properties of the hydrogel and cannot be easily altered. The recently developed ...
3D Bioprinting in Microgravity: Opportunities, Challenges, and Possible Applications in Space

Van Ombergen, Angelique; Chalupa-Gantner, Franziska; Chansoria, Parth; Colosimo, Bianca Maria; Costantini, Marco; Domingos, Marco; Dufour, Alexandre; De Maria, Carmelo; Groll, Jürgen; Jungst, Tomasz; Levato, Riccardo; Malda, Jos; Margarita, Alessandro; Marquette, Christophe; Ovsianikov, Aleksandr; Petiot, Emma; Read, Sophia; Surdo, Leonardo; Swieszkowski, Wojciech; Vozzi, Giovanni; Windisch, Johannes; Zenobi-Wong, Marcy; Gelinsky, Michael (John Wiley & Sons Inc., 2023-09-13)

3D bioprinting has developed tremendously in the last couple of years and enables the fabrication of simple, as well as complex, tissue models. The international space agencies have recognized the unique opportunities of ...
Volumetric Printing Across Melt Electrowritten Scaffolds Fabricates Multi-Material Living Constructs with Tunable Architecture and Mechanics

Größbacher, Gabriel; Bartolf-Kopp, Michael; Gergely, Csaba; Bernal, Paulina Núñez; Florczak, Sammy; de Ruijter, Mylène; Rodriguez, Núria Ginés; Groll, Jürgen; Malda, Jos; Jungst, Tomasz; Levato, Riccardo (Wiley-Blackwell, 2023-08-10)

Major challenges in biofabrication revolve around capturing the complex, hierarchical composition of native tissues. However, individual 3D printing techniques have limited capacity to produce composite biomaterials with ...
Evaluation of surgical fixation methods for the implantation of melt electrowriting-reinforced hyaluronic acid hydrogel composites in porcine cartilage defects

Galarraga, Jonathan H.; Zlotnick, Hannah M.; Locke, Ryan C.; Gupta, Sachin; Fogarty, Natalie L.; Masada, Kendall M.; Stoeckl, Brendan D.; Laforest, Lorielle; Castilho, Miguel; Malda, Jos; Levato, Riccardo; Carey, James L.; Mauck, Robert L.; Burdick, Jason A. (Whioce Publishing Pte. Ltd, 2023)

The surgical repair of articular cartilage remains an ongoing challenge in orthopedics. Tissue engineering is a promising approach to treat cartilage defects; however, scaffolds must (i) possess the requisite material ...
Convergence of melt electrowriting and extrusion-based bioprinting for vascular patterning of a myocardial construct

Ainsworth, Madison Jade; Chirico, Nino; de Ruijter, Mylène; Hrynevich, Andrei; Dokter, Inge; Sluijter, Joost P.G.; Malda, Jos; van Mil, Alain; Castilho, Miguel (IOP Publishing Ltd., 2023-07-01)

To progress cardiac tissue engineering strategies closer to the clinic, thicker constructs are required to meet the functional need following a cardiac event. Consequently, pre-vascularization of these constructs needs to ...
Nanoscale β-TCP-Laden GelMA/PCL Composite Membrane for Guided Bone Regeneration

Mahmoud, Abdel H.; Han, Yuanyuan; Dal-Fabbro, Renan; Daghrery, Arwa; Xu, Jinping; Kaigler, Darnell; Bhaduri, Sarit B.; Malda, Jos; Bottino, Marco C. (American Chemical Society, 2023-07-12)

Major advances in the field of periodontal tissue engineering have favored the fabrication of biodegradable membranes with tunable physical and biological properties for guided bone regeneration (GBR). Herein, we engineered ...
Biofunctionalization of 3D printed collagen with bevacizumab-loaded microparticles targeting pathological angiogenesis

Abbadessa, Anna; Nuñez Bernal, Paulina; Buttitta, Giorgio; Ronca, Alfredo; D'Amora, Ugo; Zihlmann, Carla; Stiefel, Niklaus; Ambrosio, Luigi; Malda, Jos; Levato, Riccardo; Crecente-Campo, José; Alonso, María José (Elsevier, 2023-08)

Pathological angiogenesis is a crucial attribute of several chronic diseases such as cancer, age-related macular degeneration, and osteoarthritis (OA). In the case of OA, pathological angiogenesis mediated by the vascular ...
Maleic acid is a biomarker for maleylacetoacetate isomerase deficiency; implications for newborn screening of tyrosinemia type 1

van Vliet, K.; Dijkstra, A. M.; Bouva, M. J.; van der Krogt, J.; Bijsterveld, K.; van der Sluijs, F.; de Sain-van der Velden, M. G.; Koop, K.; Rossi, A.; Thomas, J. A.; Patera, C. A.; Kiewiet, M. B.G.; Waters, P. J.; Cyr, D.; Boelen, A.; van Spronsen, F. J.; Heiner-Fokkema, M. R. (Springer Netherlands, 2023-11)

Dried blood spot succinylacetone (SA) is often used as a biomarker for newborn screening (NBS) for tyrosinemia type 1 (TT1). However, false-positive SA results are often observed. Elevated SA may also be due to maleylacetoacetate ...
Prognostic factors for multi-organ dysfunction in pediatric oncology patients admitted to the pediatric intensive care unit

Soeteman, Marijn; Fiocco, Marta F; Nijman, Joppe; Bollen, Casper W; Marcelis, Maartje M; Kilsdonk, Ellen; Nieuwenhuis, Edward E S; Kappen, Teus H; Tissing, Wim J E; Wösten-van Asperen, Roelie M (Frontiers Media S. A., 2023-07-12)

BACKGROUND: Pediatric oncology patients who require admission to the pediatric intensive care unit (PICU) have worse outcomes compared to their non-cancer peers. Although multi-organ dysfunction (MOD) plays a pivotal role ...
Effects of different obesogenic diets on joint integrity, inflammation and intermediate monocyte levels in a rat groove model of osteoarthritis

Warmink, K; Rios, J L; van Valkengoed, D R; Vinod, P; Korthagen, N M; Weinans, H (Frontiers Research Foundation, 2023)

Introduction: Obesogenic diets aggravate osteoarthritis (OA) by inducing low-grade systemic inflammation, and diet composition may affect OA severity. Here, we investigated the effect of diet on joint damage and inflammation ...
Smoking and colorectal neoplasia in patients with inflammatory bowel disease: Dose-effect relationship

Dutch Initiative on Crohn's and Colitis (ICC) (John Wiley & Sons Inc., 2023-09)

Background and Aims: Prior studies on the effect of smoking on the risk of colitis-associated colorectal neoplasia (CRN) have reported conflicting results. We aimed to further elucidate the association between smoking, ...
Erratum: Factors influencing scar formation following Bacille Calmette-Guérin (BCG) vaccination (Heliyon (2023) 9(4), (S2405844023024489), (10.1016/j.heliyon.2023.e15241))

Villanueva, Paola; Crawford, Nigel W; Croda, Mariana Garcia; Collopy, Simone; Jardim, Bruno Araújo; de Almeida Pinto Jardim, Tyane; Manning, Laurens; Lucas, Michaela; Marshall, Helen; Prat-Aymerich, Cristina; Sawka, Alice; Sharma, Ketaki; Troeman, Darren; Wadia, Ushma; Warris, Adilia; Wood, Nicholas; Messina, Nicole L; Curtis, Nigel; Pittet, Laure F (Elsevier, 2023-06)

The prevalence of scar formation following Bacille Calmette-Guérin (BCG) vaccination varies globally. The beneficial off-target effects of BCG are proposed to be stronger amongst children who develop a BCG scar. Within an ...
Survival of Patients with Deficient Mismatch Repair Versus Proficient Mismatch Repair Metastatic Colorectal Cancer Receiving Curative-Intent Local Treatment of Metastases in a Nationwide Cohort

Zwart, Koen; van der Baan, Frederieke H; Punt, Cornelis J A; Wensink, G Emerens; Bolhuis, Karen; Laclé, Miangela M; van Grevenstein, Wilhelmina M U; Hagendoorn, Jeroen; de Hingh, Ignace H; Koopman, Miriam; Vink, Geraldine; Roodhart, Jeanine (Springer New York, 2023-10)

BACKGROUND: It is unclear whether curative-intent local therapy of metastases is of similar benefit for the biological distinct subgroup of patients with deficient mismatch repair (dMMR) metastatic colorectal cancer (mCRC) ...
The importance of discriminative power rather than significance when evaluating potential clinical biomarkers in epilepsy research

Slinger, Geertruida; Stevelink, Remi; van Diessen, Eric; Braun, Kees P J; Otte, Willem M (John Wiley & Sons Inc., 2023-06)

OBJECTIVE: The quest for epilepsy biomarkers is on the rise. Variables with statistically significant group-level differences are often misinterpreted as biomarkers with sufficient discriminative power. This study aimed ...
Late gevolgen van radiotherapie na borstkanker

Batenburg, Marilot; Accord-Maass, Saskia; van der Leij, Femke; Verkooijen, Helena (Bohn Stafleu van Loghum, 2023-05)
Colorectal liver metastases that survive radioembolization display features of aggressive tumor behavior

Andel, Daan; Hagendoorn, Jeroen; Alsultan, Ahmed Aziz; Lacle, Miangela Marie; Smits, Maarten Leonard Johannes; Braat, Arthur Johannes Anthonius Theodorus; Kranenburg, Onno; Lam, Marnix Gerard Ernest Hendrik; Borel Rinkes, Inne Hilbrand Max (John Wiley & Sons Inc., 2023-11)

Background: Radiation lobectomy is a therapeutic approach that involves targeted radiation delivery to induce future liver remnant hypertrophy and tumor control. In patients with colorectal liver metastases, only 30–40% ...

Now showing items 9441-9460 of 40729