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Now showing items 9261-9280 of 40729

Prevalence, time trends, and correlates of major depressive episode and other psychiatric conditions among young people amid major social unrest and COVID-19 in Hong Kong: a representative epidemiological study from 2019 to 2022

Wong, Stephanie M.Y.; Chen, Eric Y.H.; Suen, Y. N.; Wong, Corine S.M.; Chang, W. C.; Chan, Sherry K.W.; McGorry, Patrick D.; Morgan, Craig; van Os, Jim; McDaid, David; Jones, Peter B.; Lam, T. H.; Lam, Linda C.W.; Lee, Edwin H.M.; Tang, Eric Y.H.; Ip, Charlie H.; Ho, Winky W.K.; McGhee, Sarah M.; Sham, P. C.; Hui, Christy L.M. (Elsevier, 2023-11)

Background: Hong Kong is among the many populations that has experienced the combined impacts of social unrest and the COVID-19 pandemic. Despite concerns about further deteriorations in youth mental health globally, few ...
Gene-environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding

Klingenberg, Boris; Guloksuz, Sinan; Pries, Lotta Katrin; Cinar, Ozan; Menne-Lothmann, Claudia; Decoster, Jeroen; Van Winkel, Ruud; Collip, Dina; Delespaul, Philippe; De Hert, Marc; Derom, Catherine; Thiery, Evert; Jacobs, Nele; Wichers, Marieke; Lin, Bochao D.; Luykx, Jurjen; Van Os, Jim; Rutten, Bart P.F. (Cambridge University Press, 2023-08-04)

The present study examines whether neuroticism is predicted by genetic vulnerability, summarized as polygenic risk score for neuroticism (PRSN), in interaction with bullying, parental bonding, and childhood adversity. Data ...
Differences in Intrinsic Gray Matter Connectivity and Their Genomic Underpinnings in Autism Spectrum Disorder

the EU-AIMS LEAP group (Elsevier, 2024-01-15)

Background: Autism is a heterogeneous neurodevelopmental condition accompanied by differences in brain connectivity. Structural connectivity in autism has mainly been investigated within the white matter. However, many ...
Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis

Genetic Risk and Outcome of Psychosis (GROUP) Study (Oxford University Press, 2023-11-01)

BACKGROUND AND HYPOTHESIS: Endophenotypes can help to bridge the gap between psychosis and its genetic predispositions, but their underlying mechanisms remain largely unknown. This study aims to identify biological mechanisms ...
Screening and prevalence of cardiometabolic risk factors in patients with severe mental illness: A multicenter cross-sectional cohort study in the Netherlands

Noortman, Laurien; de Winter, Lars; van Voorst, Arno; Cahn, Wiepke; Deenik, Jeroen (W.B. Saunders, 2023-10)

Background: Due to increased cardiometabolic risks and premature mortality in people with severe mental illness (SMI), monitoring cardiometabolic health is considered essential. We aimed to analyse screening rates and ...
Association of Risk Variants in the CFH Gene With Elevated Levels of Coagulation and Complement Factors in Idiopathic Multifocal Choroiditis

de Groot, Evianne L.; Ossewaarde-van Norel, Jeannette; de Boer, Joke H.; Hiddingh, Sanne; Bakker, Bjorn; van Huet, Ramon A.C.; Ten Dam-van Loon, Ninette H.; Thiadens, Alberta A.H.J.; Meester-Smoor, Magda A.; de Jong-Hesse, Yvonne; Los, Leonoor I.; den Hollander, Anneke I.; Boon, Camiel J.F.; Kiemeney, Lambertus A.; van Eijk, Kristel R.; Bakker, Mark K.; Hoyng, Carel B.; Kuiper, Jonas J.W. (American Medical Association, 2023-08-17)

Importance: Idiopathic multifocal choroiditis (MFC) is poorly understood, thereby hindering optimal treatment and monitoring of patients. Objective: To identify the genes and pathways associated with idiopathic MFC. Design, ...
Video Grading of Descemet Membrane Endothelial Keratoplasty Surgery to Identify Surgeon Risk Factors for Graft Detachment and Rebubbling: A Post Hoc Observational Analysis of the Advanced Visualization In Corneal Surgery Evaluation Trial

Muijzer, Marc B.; Delbeke, Heleen; Dickman, Mor M.; Nuijts, Rudy M.M.A.; Jimale, Hanad; Van Luijk, Chantal M.; Imhof, Saskia M.; Wisse, Robert P.L. (Lippincott Williams & Wilkins, 2023-09-01)

Purpose:The aim of this study was to explore video-graded intraoperative risk factors for graft detachment (GD) and rebubbling in Descemet membrane endothelial keratoplasty surgery.Methods:A post hoc analysis of 65 eyes ...
The TeleTriageTeam, Offering Continuity of Personalized Care Through Telemedicine: Development and Evaluation

Claessens, Janneau; Mueller-Schotte, Sigrid; van Weerden, Jeannette; Kort, Helianthe; Imhof, Saskia; Wisse, Robert (JMIR Publications Inc., 2023-07-28)

Background: The COVID-19 pandemic taught us how to rethink care delivery. It catalyzed creative solutions to amplify the potential of personnel and facilities. This paper presents and evaluates a promptly introduced triaging ...
The interaction of thrombocytopenia, hemorrhage, and platelet transfusion in venoarterial extracorporeal membrane oxygenation: a multicenter observational study

Raasveld, Senta Jorinde; van den Oord, Claudia; Schenk, Jimmy; van den Bergh, Walter M.; Oude Lansink - Hartgring, Annemieke; van der Velde, Franciska; Maas, Jacinta J.; van de Berg, Pablo; Lorusso, Roberto; Delnoij, Thijs S.R.; Dos Reis Miranda, Dinis; Scholten, Erik; Taccone, Fabio Silvio; Dauwe, Dieter F.; De Troy, Erwin; Hermans, Greet; Pappalardo, Federico; Fominskiy, Evgeny; Ivancan, Višnja; Bojčić, Robert; de Metz, Jesse; van den Bogaard, Bas; Donker, Dirk W.; Meuwese, Christiaan L.; De Bakker, Martin; Reddi, Benjamin; Henriques, José P.S.; Broman, Lars Mikael; Dongelmans, Dave A.; Vlaar, Alexander P.J. (Springer Science + Business Media, 2023-08-21)

Background: Thrombocytopenia, hemorrhage and platelet transfusion are common in patients supported with venoarterial extracorporeal membrane oxygenation (VA ECMO). However, current literature is limited to small single-center ...
Plasma Transfusion and Procoagulant Product Administration in Extracorporeal Membrane Oxygenation: A Secondary Analysis of an International Observational Study on Current Practices

Van Haeren, Maite M.T.; Raasveld, Senta Jorinde; Karami, Mina; Miranda, Dinis Dos Reis; Mandigers, Loes; Dauwe, Dieter F.; De Troy, Erwin; Pappalardo, Federico; Fominskiy, Evgeny; Van Den Bergh, Walter M.; Oude Lansink-Hartgring, Annemieke; Van Der Velde, Franciska; Maas, Jacinta J.; Van De Berg, Pablo; De Haan, Maarten; Donker, Dirk W.; Meuwese, Christiaan L.; Taccone, Fabio Silvio; Peluso, Lorenzo; Lorusso, Roberto; Delnoij, Thijs S.R.; Scholten, Erik; Overmars, Martijn; Ivancan, Višnja; Bojčić, Robert; De Metz, Jesse; Van Den Bogaard, Bas; De Bakker, Martin; Reddi, Benjamin; Hermans, Greet; Broman, Lars Mikael; Henriques, José P.S.; Schenk, Jimmy; Vlaar, Alexander P.J.; Müller, Marcella C.A. (Lippincott Williams & Wilkins, 2023-08-21)

OBJECTIVES: To achieve optimal hemostatic balance in patients on extracorporeal membrane oxygenation (ECMO), a liberal transfusion practice is currently applied despite clear evidence. We aimed to give an overview of the ...
Lethal Respiratory Syncytial Virus in Zambia Is Sensitive to Long-acting Monoclonal Antibodies

Langedijk, Annefleur C; Vrancken, Bram; Lebbink, Robert Jan; Evers, Anouk; Pieciak, Rachel C; Lemey, Philippe; Bont, Louis J; Gill, Christopher J (Lippincott Williams & Wilkins, 2023-11)
Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants

MATISSE Study Group (Massachussetts Medical Society, 2023-04-20)

BACKGROUND: Whether vaccination during pregnancy could reduce the burden of respiratory syncytial virus (RSV)-associated lower respiratory tract illness in newborns and infants is uncertain. METHODS: In this phase 3, ...
Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults

RENOIR Clinical Trial Group (Massachussetts Medical Society, 2023-04-20)

BACKGROUND: Respiratory syncytial virus (RSV) infection causes considerable illness in older adults. The efficacy and safety of an investigational bivalent RSV prefusion F protein-based (RSVpreF) vaccine in this population ...
Incidence of Respiratory Syncytial Virus Infection in Older Adults: Limitations of Current Data

Rozenbaum, Mark H.; Begier, Elizabeth; Kurosky, Samantha K.; Whelan, Jo; Bem, Danai; Pouwels, Koen B.; Postma, Maarten; Bont, Louis (Springer Healthcare, 2023-06)

Introduction: Respiratory syncytial virus (RSV) is an important cause of severe respiratory illness in older adults and adults with respiratory or cardiovascular comorbidities. Published estimates of its incidence and ...
Respiratory syncytial virus infection and novel interventions

Langedijk, Annefleur C.; Bont, Louis J. (Nature Research, 2023-11)

The large global burden of respiratory syncytial virus (RSV) respiratory tract infections in young children and older adults has gained increased recognition in recent years. Recent discoveries regarding the neutralizati ...
Higher off-target amplicon detection rate in MiSeq v3 compared to v2 reagent kits in the context of 16S-rRNA-sequencing

Odendaal, Mari Lee; Groot, James A.; Hasrat, Raiza; Chu, Mei Ling J.N.; Franz, Eelco; Bogaert, Debby; Bosch, Thijs; de Steenhuijsen Piters, Wouter A.A. (Nature Publishing Group, 2022-10-01)

One of the most widely used techniques in microbiota research is 16S-rRNA-sequencing. Several laboratory processes have been shown to impact sequencing results, especially in low biomass samples. Low biomass samples are ...
Mode of delivery modulates the intestinal microbiota and impacts the response to vaccination

de Koff, Emma M.; van Baarle, Debbie; van Houten, Marlies A.; Reyman, Marta; Berbers, Guy A.M.; van den Ham, Femke; Chu, Mei Ling J.N.; Sanders, Elisabeth A.M.; Bogaert, Debby; Fuentes, Susana (Nature Publishing Group, 2022-11-15)

The gut microbiota in early life, when critical immune maturation takes place, may influence the immunogenicity of childhood vaccinations. Here we assess the association between mode of delivery, gut microbiota development ...
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites

Bogaert, Debby; van Beveren, Gina J.; de Koff, Emma M.; Lusarreta Parga, Paula; Balcazar Lopez, Carlos E.; Koppensteiner, Lilian; Clerc, Melanie; Hasrat, Raiza; Arp, Kayleigh; Chu, Mei Ling J.N.; de Groot, Pieter C.M.; Sanders, Elisabeth A.M.; van Houten, Marlies A.; de Steenhuijsen Piters, Wouter A.A. (Cell Press, 2023-03-08)

Early-life microbiota seeding and subsequent development is crucial to future health. Cesarean-section (CS) birth, as opposed to vaginal delivery, affects early mother-to-infant transmission of microbes. Here, we assess ...
Asymptomatic Viral Presence in Early Life Precedes Recurrence of Respiratory Tract Infections

Zuurbier, Roy P.; Bogaert, Debby; De Steenhuijsen Piters, Wouter A.A.; Arp, Kayleigh; Chu, Mei Ling J.N.; Sanders, Elisabeth A.M.; Van Houten, Marlies A. (Lippincott Williams & Wilkins, 2023-01-01)

Background: Respiratory tract infections (RTIs) in infants are often caused by viruses. Although respiratory syncytial virus (RSV), influenza virus and human metapneumovirus (hMPV) can be considered the most pathogenic ...
Therapeutic Targeting of the Respiratory Microbiome

Chotirmall, Sanjay H.; Bogaert, Debby; Chalmers, James D.; Cox, Michael J.; Hansbro, Philip M.; Huang, Yvonne J.; Molyneaux, Philip L.; O’Dwyer, David N.; Pragman, Alexa A.; Rogers, Geraint B.; Segal, Leopoldo N.; Dickson, Robert P. (American Thoracic Society, 2022-09-01)

Now showing items 9261-9280 of 40729