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UMC Repository: Recent submissions

  • Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries 
    Tong, Tammy Y.N.; Clarke, Robert; Schmidt, Julie A.; Huybrechts, Inge; Noor, Urwah; Forouhi, Nita G.; Imamura, Fumiaki; Travis, Ruth C.; Weiderpass, Elisabete; Aleksandrova, Krasimira; Dahm, Christina C.; van der Schouw, Yvonne T.; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Kaaks, Rudolf; Katzke, Verena; Schiborn, Catarina; Schulze, Matthias B.; Mayen-Chacon, Ana Lucia; Masala, Giovanna; Sieri, Sabina; de Magistris, Maria Santucci; Tumino, Rosario; Sacerdote, Carlotta; Boer, Jolanda M.A.; Verschuren, W. M.Monique; Brustad, Magritt; Nøst, Therese Haugdahl; Crous-Bou, Marta; Petrova, Dafina; Amiano, Pilar; Huerta, José María; Moreno-Iribas, Conchi; Engström, Gunnar; Melander, Olle; Johansson, Kristina; Lindvall, Kristina; Aglago, Elom K.; Heath, Alicia K.; Butterworth, Adam S.; Danesh, John; Key, Timothy J. (Springer Science and Business Media Deutschland GmbH, 2024-02)
    Purpose: Previously reported associations of protein-rich foods with stroke subtypes have prompted interest in the assessment of individual amino acids. We examined the associations of dietary amino acids with risks of ...
  • Setting a realistic AWaRe target for primary care antibiotic use in LMICs 
    Ingelbeen, Brecht; Valia, Daniel; Phanzu, Delphin Mavinga; van der Sande, Marianne A.B.; Tinto, Halidou (Elsevier Limited, 2023-02)
  • Healthcare seeking outside healthcare facilities and antibiotic dispensing patterns in rural Burkina Faso: A mixed methods study 
    Valia, Daniel; Kouanda, Juste Stéphane; Ingelbeen, Brecht; Derra, Karim; Kaboré, Bérenger; Kiemdé, François; Rouamba, Toussaint; Rouamba, Eli; Hien, Franck Sovi; Campbell, Linda; Meudec, Marie; Robert, Annie; Tinto, Halidou; van der Sande, Marianne A.B.; Villalobos, Hector Rodriguez (Wiley-Blackwell, 2023-05)
    Objective: Optimising antibiotic use is important to limit increasing antibiotic resistance. In rural Burkina Faso, over-the-counter dispensing of antibiotics in community pharmacies and non-licensed medicine retail outlets ...
  • A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa 
    Van Puyvelde, Sandra; de Block, Tessa; Sridhar, Sushmita; Bawn, Matt; Kingsley, Robert A.; Ingelbeen, Brecht; Beale, Mathew A.; Barbé, Barbara; Jeon, Hyon Jin; Mbuyi-Kalonji, Lisette; Phoba, Marie France; Falay, Dadi; Martiny, Delphine; Vandenberg, Olivier; Affolabi, Dissou; Rutanga, Jean Pierre; Ceyssens, Pieter Jan; Mattheus, Wesley; Cuypers, Wim L.; van der Sande, Marianne A.B.; Park, Se Eun; Kariuki, Simon; Otieno, Kephas; Lusingu, John P.A.; Mbwana, Joyce R.; Adjei, Samuel; Sarfo, Anima; Agyei, Seth O.; Asante, Kwaku P.; Otieno, Walter; Otieno, Lucas; Tahita, Marc C.; Lompo, Palpouguini; Hoffman, Irving F.; Mvalo, Tisungane; Msefula, Chisomo; Hassan-Hanga, Fatimah; Obaro, Stephen; Mackenzie, Grant; Deborggraeve, Stijn; Feasey, Nicholas; Marks, Florian; MacLennan, Calman A.; Thomson, Nicholas R.; Jacobs, Jan; Dougan, Gordon; Kariuki, Samuel; Lunguya, Octavie (Nature Publishing Group, 2023-10-23)
    Invasive non-typhoidal Salmonella (iNTS) disease manifesting as bloodstream infection with high mortality is responsible for a huge public health burden in sub-Saharan Africa. Salmonella enterica serovar Typhimurium (S. ...
  • De novo pain and relief of pain after abdominal synthetic mesh implants 
    Koops, Steven E.Schraffordt; Schreuder, Henk W.R.; Heydanus, Laure; van Zanten, Femke (2022-12)
    Introduction: This study assessed the incidence, severity and risk factors for pain after abdominal mesh usage in pelvic floor prolapse surgery. Methods: Prospective observational cohort study (NCT01598467, clinical ...
  • Diagnostic Gene Panel Testing in (Non)-Syndromic Patients with Cleft Lip, Alveolus and/or Palate in the Netherlands 
    Wurfbain, Lisca Florence; Cox, Inge Lucia; van Dooren, Maria Francisca; Lachmeijer, Augusta Maria Antonia; Verhoeven, Virginie Johanna Maria; van Hagen, Johanna Maria; Heijligers, Malou; Klein Wassink-Ruiter, Jolien Sietske; Koene, Saskia; Maas, Saskia Mariska; Veenstra-Knol, Hermine Elisabeth; Ploos van Amstel, Johannes Kristian; Massink, Maarten Pieter Gerrit; Mink van der Molen, Aebele Barber; van den Boogaard, Marie-José Henriette (S. Karger AG, 2023-08-01)
    OBJECTIVES: Clefts of the lip, alveolus and/or palate (CLA/P) are the most common craniofacial congenital malformations in humans. These oral clefts can be divided into non-syndromic (isolated) and syndromic forms. Many ...
  • Predictive factors for allergy at 4–6 years of age based on machine learning: A pilot study 
    Kamphorst, Kim; Lopez-Rincon, Alejandro; Vlieger, Arine M.; Garssen, Johan; Riet, Esther van ’t; Elburg, Ruurd M. van (Elsevier, 2023-03)
    Background In Europe, allergic diseases are the most common chronic childhood illnesses and the result of a complex interplay between genetics and environmental factors. A new approach for analyzing this complex data is ...
  • Classifying asthma control using salivary and fecal bacterial microbiome in children with moderate-to-severe asthma 
    SysPharmPediA Consortium (Blackwell Munksgaard, 2023-02)
    BACKGROUND: Uncontrolled asthma can lead to severe exacerbations and reduced quality of life. Research has shown that the microbiome may be linked with asthma characteristics; however, its association with asthma control ...
  • In vivo and ex vivo inflammatory responses of the esophageal mucosa to food challenge in adults with eosinophilic esophagitis 
    Haasnoot, Maria L; Kleuskens, Mirelle T A; Lopez-Rincon, Alejandro; Diks, Mara A P; Terreehorst, Ingrid; Akkerdaas, Jaap H; van Ree, Ronald; van Ampting, Marleen T J; Garssen, Johan; Redegeld, Frank A; van Esch, Betty C A M; Bredenoord, Albert J (Wiley-Blackwell, 2023-07)
  • In Silico Screening of Drugs That Target Different Forms of E Protein for Potential Treatment of COVID-19 
    Ramírez Salinas, Gema Lizbeth; López Rincón, Alejandro; García Machorro, Jazmín; Correa Basurto, José; Martínez Archundia, Marlet (Multidisciplinary Digital Publishing Institute, 2023-02-14)
    Recently the E protein of SARS-CoV-2 has become a very important target in the potential treatment of COVID-19 since it is known to regulate different stages of the viral cycle. There is biochemical evidence that E protein ...
  • An Innovative AI-based primer design tool for precise and accurate detection of SARS-CoV-2 variants of concern 
    Perez-Romero, Carmina Angelica; Mendoza-Maldonado, Lucero; Tonda, Alberto; Coz, Etienne; Tabeling, Patrick; Vanhomwegen, Jessica; MacSharry, John; Szafran, Joanna; Bobadilla-Morales, Lucina; Corona-Rivera, Alfredo; Claassen, Eric; Garssen, Johan; Kraneveld, Aletta D; Lopez-Rincon, Alejandro (Nature Publishing Group, 2023-12)
    As the COVID-19 pandemic winds down, it leaves behind the serious concern that future, even more disruptive pandemics may eventually surface. One of the crucial steps in handling the SARS-CoV-2 pandemic was being able to ...
  • Effectiveness of a guided online primary care intervention for fear of cancer recurrence: A randomised controlled trial 
    Luigjes-Huizer, Yvonne L.; Helsper, Charles W.; de Wit, Niek J.; van der Lee, Marije L. (John Wiley & Sons Inc., 2023-12)
    Objective: Fear of Cancer Recurrence (FCR) is highly prevalent among cancer survivors and leads to decreased quality of life and increased healthcare costs. We assessed the effectiveness of a guided online primary care ...
  • The CombiConsultation for patients with diabetes, COPD and cardiovascular diseases: Evaluation of interventions and personal health-related goals 
    Meijvis, Valérie A.M.; Heringa, Mette; Kwint, Henk Frans; de Wit, Niek J.; Bouvy, Marcel L. (Elsevier, 2023-07)
    Background: The CombiConsultation is a consultation with the community pharmacist for patients with diabetes, COPD and/or cardiovascular disease (CVD), aligned with the annual or quarterly consultation with the practice ...
  • Population-based impact of COVID-19 on incidence, treatment, and survival of patients with pancreatic cancer 
    for the Dutch Pancreatic Cancer Group (DPCG) and the COVID & Cancer-NL consortium; Dutch Nationwide Pathology Databank (Pathologisch-Anatomisch Landelijk Geautomatiseerd Archief, PALGA); SONCOS (Dutch Multidisciplinary Oncology Foundation) (John Wiley & Sons Inc., 2023-10)
    Background: The COVID-19 pandemic has put substantial strain on the healthcare system of which the effects are only partly elucidated. This study aimed to investigate the impact on pancreatic cancer care. Methods: All ...
  • Barriers and facilitators for the implementation of the CombiConsultation by general practitioners, pharmacists and practice nurses: a qualitative interview study 
    Meijvis, Valérie A.M.; Heringa, Mette; Kwint, Henk Frans; de Wit, Niek J.; Bouvy, Marcel L. (Springer Netherlands, 2023-08)
    Background: The CombiConsultation is a consultation with the pharmacist for patients with a chronic condition, aligned with the periodic consultation with the practice nurse or general practitioner. Implementation requires ...
  • Patients’ views on the decision to investigate cancer symptoms in older adults:: a qualitative interview study in primary care 
    Jones, Daniel; Ali, Omer M.; Honey, Stephanie; Surr, Claire; Scott, Suzanne; De Wit, Niek; Neal, Richard D. (Royal College of General Practitioners, 2023-08)
    Background Cancer is predominantly a disease of older adults. To date there has been little research on the experiences of older adults or their views on the diagnostic pathway. Aim To gain an improved understanding of the ...
  • Hemofiltration Improves Blood Perfusate Conditions Leading to Improved Ex Situ Heart Perfusion 
    Kaffka Genaamd Dengler, Selma E; Mishra, Mudit; Vervoorn, Mats T; Kernkamp, Jord; van Tuijl, Sjoerd; de Jager, Saskia C A; Sluijter, Joost P G; Doevendans, Pieter A; van der Kaaij, Niels P (Lippincott Williams & Wilkins, 2024-01-01)
    The aim was to optimize the perfusate composition by including a hemofiltrator to the PhysioHeartplatform for ex situ heart perfusion of porcine slaughterhouse hearts. Fourteen hearts were harvested from Dutch Landrace ...
  • Introducing a novice surgeon to an experienced robotic gynaecological oncology team: An observational cohort study on the impact of a structured curriculum on outcomes of cervical cancer surgery 
    Baeten, Ilse G.T.; Hoogendam, Jacob P.; Schreuder, Henk W.R.; Jürgenliemk-Schulz, Ina M.; Gerestein, Cornelis G.; Zweemer, Ronald P. (Academic Press Inc., 2023-11)
    Objective: To evaluate the effect on patient outcomes when introducing a novice robotic surgeon, trained in accordance with a structured learning curriculum, to an experienced robotic surgery team treating cervical cancer ...
  • Modulating design parameters to drive cell invasion into hydrogels for osteochondral tissue formation 
    Schwab, Andrea; Wesdorp, Marinus A.; Xu, Jietao; Abinzano, Florencia; Loebel, Claudia; Falandt, Marc; Levato, Riccardo; Eglin, David; Narcisi, Roberto; Stoddart, Martin J.; Malda, Jos; Burdick, Jason A.; D'Este, Matteo; van Osch, Gerjo J.V.M. (Elsevier (Singapore) Pte Ltd, 2023-07)
    Background: The use of acellular hydrogels to repair osteochondral defects requires cells to first invade the biomaterial and then to deposit extracellular matrix for tissue regeneration. Due to the diverse physicochemical ...
  • Shaping Synthetic Multicellular and Complex Multimaterial Tissues via Embedded Extrusion-Volumetric Printing of Microgels 
    Ribezzi, Davide; Gueye, Marième; Florczak, Sammy; Dusi, Franziska; de Vos, Dieuwke; Manente, Francesca; Hierholzer, Andreas; Fussenegger, Martin; Caiazzo, Massimiliano; Blunk, Torsten; Malda, Jos; Levato, Riccardo (Wiley-Blackwell, 2023-09-07)
    In living tissues, cells express their functions following complex signals from their surrounding microenvironment. Capturing both hierarchical architectures at the micro- and macroscale, and anisotropic cell patterning ...