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Variability in benefit from intensive insulin therapy on cardiovascular events in individuals with type 1 diabetes: A post hoc analysis of the DCCT/EDIC study

Helmink, Marga A.G.; Hageman, Steven H.J.; Visseren, Frank L.J.; de Ranitz-Greven, Wendela L.; de Valk, Harold W.; van Sloten, Thomas T.; Westerink, Jan (Wiley-Blackwell, 2023-11)

Aim: To evaluate presence of treatment effect heterogeneity of intensive insulin therapy (INT) on occurrence of major adverse cardiovascular events (MACE) in individuals with type 1 diabetes. Methods: In participants from ...
Dual hormone fully closed loop in type 1 diabetes: a randomised trial in the Netherlands - study protocol

Jančev, Milena; Snoek, Frank J.; Frederix, Geert W.J.; Knottnerus, Heleen; Blauw, Helga; Witkop, Maureen; Moons, Karel G.M.; Van Bon, Arianne C.; Devries, J. Hans; Serné, Erik H.; Van Sloten, Thomas T.; De Valk, Harold W. (BMJ Publishing Group, 2023-08-23)

Introduction The management of type 1 diabetes (T1DM) has undergone significant advancements with the availability of novel technologies, notably continuous and flash glucose monitoring (CGM and FGM, respectively) and ...
Continuous glucose monitoring metrics and pregnancy outcomes in insulin-treated diabetes: A post-hoc analysis of the GlucoMOMS trial

Rademaker, Doortje; van der Wel, Anne W.T.; van Eekelen, Rik; Voormolen, Daphne N.; de Valk, Harold W.; Evers, Inge M.; Mol, Ben Willem; Franx, Arie; Siegelaar, Sarah E.; van Rijn, Bas B.; DeVries, J. Hans; Painter, Rebecca C. (Wiley-Blackwell, 2023-12)

Aim: To investigate the association between continuous glucose monitoring (CGM) metrics and perinatal outcomes in insulin-treated diabetes mellitus in pregnancy. Materials and Methods: In a post-hoc analysis of the GlucoMOMS ...
Effects of COVID-19 on diabetes care among dutch diabetes outpatients

Bak, Jessica C.G.; Serné, Erik H.; Groenwold, Rolf H.H.; de Valk, Harold W.; Kramer, Mark H.H.; Nieuwdorp, Max; Verheugt, Carianne L. (BioMed Central, 2023-12)

Aims: The COVID-19 pandemic impacted diabetes care by reducing diabetes outpatient visits and diabetes-related screening due to allocation of healthcare resources. Yet the impact of COVID-19 on diabetes outpatients has not ...
Local Control Following Stereotactic Body Radiation Therapy for Liver Oligometastases: Lessons from a Quarter Century

Mheid, Sara; Allen, Stefan; Ng, Sylvia S.W.; Hall, William A.; Sanford, Nina N.; Aguilera, Todd A.; Elamir, Ahmed M.; Bahij, Rana; Intven, Martijn P.W.; Radhakrishna, Ganesh; Mohamad, Issa; De Leon, Jeremy; Tan, Hendrick; Lewis, Shirley; Gani, Cihan; Stanecu, Teo; Dell’Acqua, Veronica; Hosni, Ali (Multidisciplinary Digital Publishing Institute (MDPI), 2023-10)

The utilization of stereotactic body radiation therapy for the treatment of liver metastasis has been widely studied and has demonstrated favorable local control outcomes. However, several predictive factors play a crucial ...
One-year safety and efficacy of mitapivat in sickle cell disease: follow-up results of a phase 2, open-label study

van Dijk, Myrthe J; Rab, Minke A E; van Oirschot, Brigitte A; Bos, Jennifer; Derichs, Cleo; Rijneveld, Anita W; Cnossen, Marjon H; Nur, Erfan; Biemond, Bart J; Bartels, Marije; Jans, Judith J M; van Solinge, W W; Schutgens, Roger E G; van Wijk, Richard; van Beers, Eduard J (The American Society of Hematology, 2023-12-26)

Targeting the primary pathogenic event of sickle cell disease (SCD), the polymerization of sickle hemoglobin (HbS), may prevent downstream clinical events. Mitapivat, an oral pyruvate kinase (PK) activator, has therapeutic ...
Aspirin as Thromboprophylaxis in Orthopedic Surgery: A Matter of Perspective

Schutgens, Roger E.G.; Middeldorp, Saskia (Wolters Kluwer Health, 2023-08-20)
Antithrombotic Treatment in Patients With Hemophilia: an EHA-ISTH-EAHAD-ESO Clinical Practice Guidance

Schutgens, Roger E.G.; Jimenez-Yuste, Victor; Escobar, Miguel; Falanga, Anna; Gigante, Bruna; Klamroth, Robert; Lassila, Riitta; Leebeek, Frank W.G.; Makris, Michael; Owaidah, Tarek; Sholzberg, Michelle; Tiede, Andreas; Werring, David J.; Van Der Worp, H. Bart; Windyga, Jerzy; Castaman, Giancarlo (Wolters Kluwer Health, 2023-06-05)

Cardiovascular disease is an emerging medical issue in patients with hemophilia (PWH) and its prevalence is increasing up to 15% in PWH in the United States. Atrial fibrillation, acute and chronic coronary syndromes, venous ...
High prevalence of heavy menstrual bleeding in women with rare bleeding disorders in the Netherlands: retrospective data from the RBiN study

RBiN study group (Wiley-Blackwell, 2023-10)

Background: Heavy menstrual bleeding (HMB) is associated with a reduced quality of life and limitations in social and physical functioning. Data on HMB in women with rare bleeding disorders (RBDs), including coagulation ...
BCR::ABL1 kinase domain mutation testing and clinical outcome in a nationwide chronic myeloid leukemia patient population

Kockerols, Camille; Valk, Peter J.M.; Blijlevens, Nicole M.A.; Cornelissen, Jan J.; Dinmohamed, Avinash G.; Geelen, Inge; Hoogendoorn, Mels; Janssen, Jeroen J.W.M.; Daenen, Laura G.M.; Reijden, Bert A.van der; Westerweel, Peter E. (Wiley-Blackwell, 2023-12)

Objectives: Acquired missense mutations in the BCR::ABL1 kinase domain (KD) may cause tyrosine kinase inhibitor (TKI) treatment failure. Based on mutation-specific in vitro derived IC50-values, alternative TKI may be ...
Is a preoperative multidisciplinary team meeting (cost)effective to improve outcome for high-risk adult patients undergoing noncardiac surgery: the PREPARATION study—a multicenter stepped-wedge cluster randomized trial

Vernooij, Jacqueline E.M.; Boerlage, Romijn M.; Doggen, Carine J.M.; Preckel, Benedikt; Dirksen, Carmen D.; van Leeuwen, Barbara L.; Spruit, Rutger J.; Festen, Suzanne; van der Wal-Huisman, Hanneke; van Basten, Jean P.; Kalkman, Cor J.; Koning, Nick J. (BioMed Central, 2023-10-11)

Background: As a result of increased life expectancy and improved care for patients suffering from chronic disease, the number of patients with multimorbidity requiring surgical intervention is increasing. For complex ...
Process Evaluation of a Wireless Wearable Continuous Vital Signs Monitoring Intervention in 2 General Hospital Wards: Mixed Methods Study

Leenen, Jobbe P.L.; Rasing, Henriëtte J.M.; Kalkman, Cor J.; Schoonhoven, Lisette; Patijn, Gijsbert A. (JMIR Publications Inc., 2023-05-04)

Background: Continuous monitoring of vital signs (CMVS) using wearable wireless sensors is increasingly available to patients in general wards and can improve outcomes and reduce nurse workload. To assess the potential ...
Quality of recovery after day care surgery with app-controlled remote monitoring: study protocol for a randomized controlled trial

Thiel, B.; Godfried, M. B.; van Emst, M. E.; Vernooij, L. M.; van Vliet, L. M.; Rumke, E.; van Dongen, R. T.M.; Gerrits, W.; Koopman, J. S.H.A.; Kalkman, C. J. (BioMed Central, 2023-02-09)

Background: The majority of surgical interventions are performed in day care and patients are discharged after the first critical postoperative period. At home, patients have limited options to contact healthcare providers ...
Performance and usability of pre-operative prediction models for 30-day peri-operative mortality risk: a systematic review

Vernooij, J. E.M.; Koning, N. J.; Geurts, J. W.; Holewijn, S.; Preckel, B.; Kalkman, C. J.; Vernooij, L. M. (Wiley-Blackwell, 2023-05)

Estimating pre-operative mortality risk may inform clinical decision-making for peri-operative care. However, pre-operative mortality risk prediction models are rarely implemented in routine clinical practice. High predictive ...
Value of improving patient safety: Health economic considerations for rapid response systems-a rapid review of the literature and expert round table

Subbe, Christian; Hughes, Dyfrig A.; Lewis, Sally; Holmes, Emily A.; Kalkman, Cor; So, Ralph; Tranka, Sumeshni; Welch, John (BMJ Publishing Group, 2023-04-17)

Objectives Failure to rescue deteriorating patients in hospital is a well-researched topic. We aimed to explore the impact of safer care on health economic considerations for clinicians, providers and policymakers. Design ...
Local production of 17β-oestradiol in the endometrium during the implantation window: a pilot study

Stevens Brentjens, L Bpm; Obukhova, D; Delvoux, B; den Hartog, J E; Bui, B N; Mol, F; de Bruin, J P; Besselink, D; Teklenburg, G; Morgan, F; Baker, M; Broekmans, F Jm; van Golde, R J T; Esteki, M Zamani; Romano, A (BioScientifica Ltd., 2023-12-13)

Sex steroids are converted to bioactive metabolites and vice versa by endometrial steroid-metabolising enzymes. Studies indicate that alterations in this metabolism might affect endometrial receptivity. This pilot study ...
Automatic measurement of short-term variability of repolarization to indicate ventricular arrhythmias in a porcine model of cardiac ischaemia

Loen, Vera; Smoczynska, Agnieszka; Hernandez, Alfonso Aranda; Scheerder, Coert O S; van der Linde, Britt H R; Beekman, Henriëtte D M; Cervera-Barea, Aina; Boink, Gerard J J; Sluijter, Joost P G; van der Heyden, Marcel A G; Meine, Mathias; Vos, Marc A (Oxford University Press, 2023-11-01)

AIMS: An automated method for determination of short-term variability (STV) of repolarization on intracardiac electrograms (STV-ARIauto) has previously been developed for arrhythmic risk monitoring by cardiac implantable ...
Mycoplasma pneumoniae carriage in children with recurrent respiratory tract infections is associated with a less diverse and altered microbiota

Koenen, Mischa H; de Groot, Ruben C A; de Steenhuijsen Piters, Wouter A A; Chu, Mei Ling J N; Arp, Kayleigh; Hasrat, Raïza; de Bruijn, Ad C J M; Estevão, Silvia C; van der Vries, Erhard; Langereis, Jeroen D; Boes, Marianne; Bogaert, Debby; van Rossum, Annemarie M C; Unger, Wendy W J; Verhagen, Lilly M (Elsevier, 2023-12)

BACKGROUND: Mycoplasma pneumoniae is a common cause of community-acquired pneumonia in school-aged children and can be preceded by asymptomatic carriage. However, its role in recurrent respiratory tract infections is ...
MHC II-EGFP Knock-in Mouse Model

Pačes, Jan; Grobárová, Valéria; Zadražil, Zdeněk; Knížková, Karolina; Malinská, Nikola; Tušková, Liliana; Boes, Marianne; Černý, Jan (John Wiley & Sons Inc., 2023-11)

The MHC II–EGFP knock-in mouse model enables us to visualize and track MHC-II-expressing cells in vivo by expressing enhanced green fluorescent protein (EGFP) fused to the MHC class II molecule under the MHC II beta chain ...
Acquiring Financial Support for Children’s Sports Participation: Co-Creating a Socially Safe Environment for Parents from Low-Income Families

van Leeuwen, Lonneke; Ruiter, Angelique; Visser, Kirsten; Lesscher, Heidi M. B.; Jonker, Merel (MDPI AG, 2023-05-12)

Despite the many benefits of club-organized sports participation for children, sports participation is lower among children from low-income families than among those from middle- or high-income families. Social safety ...

Now showing items 8661-8680 of 40729