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Now showing items 7701-7720 of 40729

Unraveling the relations between post-traumatic stress symptoms, neurocognitive functioning, and limbic white matter in pediatric brain tumor patients

Leenders, Anne E M; Kremer-Hooft van Huijsduijnen, Eva; Robalo, Bruno; van Male, Rosa; De Luca, Alberto; Kemps, Rachèl; Hoving, Eelco; Lequin, Maarten H; Grootenhuis, Martha A; Partanen, Marita (Oxford University Press, 2024-01-01)

Background. Pediatric brain tumor patients are at risk of developing neurocognitive impairments and associated white matter alterations. In other populations, post-traumatic stress symptoms (PTSS) impact cognition and white ...
Dynamic changes in perivascular space morphology predict signs of spaceflight-associated neuro-ocular syndrome in bed rest

Richmond, Sutton B.; Seidler, Rachael D.; Iliff, Jeffrey J.; Schwartz, Daniel L.; Luther, Madison; Silbert, Lisa C.; Wood, Scott J.; Bloomberg, Jacob J.; Mulder, Edwin; Lee, Jessica K.; De Luca, Alberto; Piantino, Juan (Nature Publishing Group, 2024-03-01)

During long-duration spaceflight, astronauts experience headward fluid shifts and expansion of the cerebral perivascular spaces (PVS). A major limitation to our understanding of the changes in brain structure and physiology ...
Development and Internal Validation of a Novel Nomogram Predicting the Outcome of Salvage Radiation Therapy for Biochemical Recurrence after Radical Prostatectomy in Patients without Metastases on Restaging Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography

Meijer, Dennie; van Leeuwen, Pim J.; Eppinga, Wietse S.C.; Vanneste, Ben G.L.; Meijnen, Philip; Daniels, Laurien A.; van den Bergh, Roderick C.N.; Lont, Anne P.; Bodar, Yves J.L.; Ettema, Rosemarijn H.; de Bie, Katelijne C.C.; Oudshoorn, Frederik H.K.; Nieuwenhuijzen, Jakko A.; van der Poel, Henk G.; Donswijk, Maarten L.; Heymans, Martijn W.; Oprea-Lager, Daniela E.; Schaake, Eva E.; Vis, André N. (Elsevier, 2024-03)

Background and objective: Owing to the greater use of prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) in patients with biochemical recurrence (BCR) of prostate cancer ...
House dust mite sublingual allergen immunotherapy tablet is safe and well-tolerated in Dutch clinical practice

Tempels-Pavlica, Žana; Aarts, Mark C J; Welsing, Paco M J; van der Meer, Akke-Nynke; van der Zwan, Leonard P; Uss, Elena; Knulst, André C (Frontiers Media S. A., 2024)

BACKGROUND: Half (49%) of clinically diagnosed allergic rhinitis (AR) patients are sensitized to house dust mite (HDM). If allergen avoidance and symptomatic medication fail, allergen immunotherapy may be indicated. ...
Treatment-specific risk of subsequent malignant neoplasms in five-year survivors of diffuse large B-cell lymphoma

Geurts, Y M; Neppelenbroek, S I M; Aleman, B M P; Janus, C P M; Krol, A D G; van Spronsen, D J; Plattel, W J; Roesink, J M; Verschueren, K M S; Zijlstra, J M; Koene, H R; Nijziel, M R; Schimmel, E C; de Jongh, E; Ong, F; Te Boome, L C J; van Rijn, R S; Böhmer, L H; Ta, B D P; Visser, H P J; Posthuma, E F M; Bilgin, Y M; Muller, K; van Kampen, D; So-Osman, C; Vermaat, J S P; de Weijer, R J; Kersten, M J; van Leeuwen, F E; Schaapveld, M (Elsevier, 2024-02)

BACKGROUND: The introduction of rituximab significantly improved the prognosis of diffuse large B-cell lymphoma (DLBCL), emphasizing the importance of evaluating the long-term consequences of exposure to radiotherapy, ...
Onward Spread from Liver Metastases Is a Major Cause of Multi-Organ Metastasis in a Mouse Model of Metastatic Colon Cancer

Wijler, Liza A; Viergever, Bastiaan J; Strating, Esther; van Schelven, Susanne J; Poghosyan, Susanna; Frenkel, Nicola C; Te Rietmole, Hedy; Verheem, Andre; Raats, Danielle A E; Borel Rinkes, Inne H M; Hagendoorn, Jeroen; Kranenburg, Onno (Multidisciplinary Digital Publishing Institute (MDPI), 2024-03-06)

Colorectal cancer metastasizes predominantly to the liver but also to the lungs and the peritoneum. The presence of extra-hepatic metastases limits curative (surgical) treatment options and is associated with very poor ...
What patients with advanced cancer experience as helpful in navigating their life with a long-term response: a qualitative study

Zwanenburg, Laura C.; van der Lee, Marije L.; Koldenhof, José J.; Suijkerbuijk, Karijn P.M.; Schellekens, Melanie P.J. (Springer-Verlag, 2024-03-12)

Purpose: Despite improved survival for people with advanced cancer due to new medical treatments, a growing group of long-term responders (LTRs) has to learn to live with uncertainties that affect several life domains. At ...
Covalent Grafting of Functionalized MEW Fibers to Silk Fibroin Hydrogels to Obtain Reinforced Tissue Engineered Constructs

Viola, Martina; Ainsworth, Madison J.; Mihajlovic, Marko; Cedillo-Servin, Gerardo; van Steenbergen, Mies J.; van Rijen, Mattie; de Ruijter, Mylène; Castilho, Miguel; Malda, Jos; Vermonden, Tina (American Chemical Society, 2024-03-11)

Hydrogels are ideal materials to encapsulate cells, making them suitable for applications in tissue engineering and regenerative medicine. However, they generally do not possess adequate mechanical strength to functionally ...
Experimentally-guided in silico design of engineered heart tissues to improve cardiac electrical function after myocardial infarction

Rosales, Ricardo M.; Mountris, Konstantinos A.; Oliván-Viguera, Aida; Pérez-Zabalza, María; Cedillo-Servin, Gerardo; Iglesias-García, Olalla; Hrynevich, Andrei; Castilho, Miguel; Malda, Jos; Prósper, Felipe; Doblaré, Manuel; Mazo, Manuel M.; Pueyo, Esther (Elsevier Limited, 2024-03)

Engineered heart tissues (EHTs) built from human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) showed promising results for cardiac function restoration following myocardial infarction. Nevertheless, ...
How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?

Davis, Trent; Tabury, Kevin; Zhu, Shouan; Angeloni, Debora; Baatout, Sarah; Benchoua, Alexandra; Bereiter-Hahn, Juergen; Bottai, Daniele; Buchheim, Judith Irina; Calvaruso, Marco; Carnero-Diaz, Eugénie; Castiglioni, Sara; Cavalieri, Duccio; Ceccarelli, Gabriele; Choukér, Alexander; Cialdai, Francesca; Ciofani, Gianni; Coppola, Giuseppe; Cusella, Gabriella; Degl’Innocenti, Andrea; Desaphy, Jean Francois; Frippiat, Jean Pol; Gelinsky, Michael; Genchi, Giada; Grano, Maria; Grimm, Daniela; Guignandon, Alain; Hahn, Christiane; Hatton, Jason; Herranz, Raúl; Hellweg, Christine E.; Iorio, Carlo Saverio; Karapantsios, Thodoris; van Loon, Jack J.W.A.; Lulli, Matteo; Maier, Jeanette; Malda, Jos; Mamaca, Emina; Morbidelli, Lucia; van Ombergen, Angelique; Osterman, Andreas; Ovsianikov, Aleksandr; Pampaloni, Francesco; Pavezlorie, Elizabeth; Pereda-Campos, Veronica; Przybyla, Cyrille; Puhl, Christopher; Rettberg, Petra; Rizzo, Angela Maria; Robson-Brown, Kate; Rossi, Leonardo; Russo, Giorgio; Salvetti, Alessandra; Santucci, Daniela; Sperl, Matthias; Tavella, Sara; Thielemann, Christiane; Willaert, Ronnie; Szewczyk, Nathaniel; Monici, Monica (Nature Publishing Group, 2024-02-10)

Progress in mechanobiology allowed us to better understand the important role of mechanical forces in the regulation of biological processes. Space research in the field of life sciences clearly showed that gravity plays ...
Microstructural differences in the osteochondral unit of terrestrial and aquatic mammals

Mancini, Irina A.D.; Levato, Riccardo; Ksiezarczyk, Marlena M.; Castilho, Miguel Dias; Chen, Michael; van Rijen, Mattie H.P.; Ijsseldijk, Lonneke L.; Kik, Marja; van Weeren, P. René; Malda, Jos (eLife Sciences Publications, 2023-11-27)

During evolution, animals have returned from land to water, adapting with morpho-logical modifications to life in an aquatic environment. We compared the osteochondral units of the humeral head of marine and terrestrial ...
Traumatic brain injury and bladder function: From acute to chronic phase. A literature review

Wyndaele , Jean Jacques; Wyndaele, Michel (2023-06)

Traumatic brain injury (TBI) can induce a coma and directly affect the pathways that help control lower urinary tract (LUT) function. This paper reviews the clinical and urodynamic data from the literature on LUT function ...
Improved professional competencies and leadership in PhD-prepared nurses and doctoral students after participating in the cross-national and web-based Nurse-Lead program

van Dongen, Lisa; Suidman, Lisa; Henriques, Maria Adriana; Jónsdóttir, Helga; Leino-Kilpi, Helena; Luderer, Christiane; Suhonen, Riitta; Hafsteinsdóttir, Thóra B. (Mosby Inc., 2024-03-01)

Background: Doctor of Philosophy (PhD)-prepared nurses are expected to exercise leadership in their various roles. Therefore, European nurse scholars developed a cross-national web-based Nursing Leadership and Mentoring ...
Understanding strategies that foster nurses to act as clinical leaders in hospitals: A realist review

Duprez, Veerle; Dhont, Laure; van der Cingel, Margreet; Hafsteinsdóttir, Thóra B.; Malfait, Simon (Wiley-Blackwell, 2024-04)

Aim: To identify strategies that develop clinical nursing leadership competencies among staff nurses, and to explain the contextual elements and mechanisms that underpin the development of clinical nursing leadership ...
No detrimental association between antibiotic use and immune checkpoint inhibitor therapy: an observational cohort study comparing patients with ICI-treated and TKI-treated melanoma and NSCLC

Metselaar-Albers, Marjolein; Meijerman, Irma; Engels, Ferdi; Haanen, John; Beijnen, Jos; Lalmohamed, Arief (BioMed Central Ltd., 2024-01-31)

Background The role of antibiotics in malignancies treated with immune checkpoint inhibitors (ICI) remains unclear. Several studies suggested a detrimental impact of antibiotic use on the response to ICI, but were susceptible ...
Placental Pathology Contributes to Impaired Volumetric Brain Development in Neonates With Congenital Heart Disease

CHD LifeSpan Study Group ‡ (Wiley-Blackwell, 2024-03-05)

BACKGROUND: Neonates with congenital heart disease are at risk for impaired brain development in utero, predisposing children to postnatal brain injury and adverse long-term neurodevelopmental outcomes. Given the vital ...
Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors

Feola, Sara; Hamdan, Firas; Russo, Salvatore; Chiaro, Jacopo; Fusciello, Manlio; Feodoroff, Michaela; Antignani, Gabriella; D'Alessio, Federica; Mölsä, Riikka; Stigzelius, Virpi; Bottega, Paolo; Pesonen, Sari; Leusen, Jeanette; Grönholm, Mikaela; Cerullo, Vincenzo (BioMed Central Ltd., 2024-03-08)

BACKGROUND: Cancer immunotherapy relies on using the immune system to recognize and eradicate cancer cells. Adaptive immunity, which consists of mainly antigen-specific cytotoxic T cells, plays a pivotal role in controlling ...
Machine learning-based models to predict the conversion of normal blood pressure to hypertension within 5-year follow-up

Andishgar, Aref; Bazmi, Sina; Tabrizi, Reza; Rismani, Maziyar; Keshavarzian, Omid; Pezeshki, Babak; Ahmadizar, Fariba (Public Library of Science, 2024-03-14)

BACKGROUND: Factors contributing to the development of hypertension exhibit significant variations across countries and regions. Our objective was to predict individuals at risk of developing hypertension within a 5-year ...
Within-episode repeat antibiotic prescriptions in patients with respiratory tract infections: a population-based cohort study

Lalmohamed, A; Venekamp, R P; Bolhuis, A; Souverein, P C; van de Wijgert, J; Gulliford, M; Hay, A D (W.B. Saunders Ltd, 2024-04)

Background: Antimicrobial stewardship interventions mainly focus on initial antibiotic prescriptions, with few considering within-episode repeat prescriptions. We aimed to describe the magnitude, type and determinants of ...
Substituting Low-Calorie Sweetened Beverages for Sugar-Sweetened Beverages to Prevent Obesity and Cardiometabolic Diseases: Still a Good Idea?

Chatelan, Angeline; Raeisi-Dehkordi, Hamidreza; Salehi-Abargouei, Amin (Elsevier, 2024-03)

Low-calorie sweeteners (LCSs) and LCS-containing beverages have been proposed as appropriate substitutes for caloric sugars in recent years. In this Perspective, we highlight the recent findings from observational and ...

Now showing items 7701-7720 of 40729