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Now showing items 7301-7320 of 40729

High-precision stereotactic irradiation for focal drug-resistant epilepsy versus standard treatment: a randomized waitlist-controlled trial (the PRECISION trial)

Zegers, C. M.L.; Swinnen, A.; Roumen, C.; Hoffmann, A. L.; Troost, E. G.C.; van Asch, C. J.J.; Brandts, L.; Compter, I.; Dieleman, E. M.T.; Dijkstra, J. B.; Granzier, M.; Hendriks, M.; Hofman, P.; Houben, R. M.A.; Ramaekers, B.; Ronner, H. E.; Rouhl, R. P.W.; van der Salm, S.; Santegoeds, R. G.C.; Verhoeff, J. J.; Wagner, G. L.; Zwemmer, J.; Schijns, O. E.M.G.; Colon, A. J.; Eekers, D. B.P. (BioMed Central, 2024-05-21)

Introduction: The standard treatment for patients with focal drug-resistant epilepsy (DRE) who are not eligible for open brain surgery is the continuation of anti-seizure medication (ASM) and neuromodulation. This treatment ...
Early life ambient air pollution, household fuel use, and under-5 mortality in Ghana

Moro, Ali; Nonterah, Engelbert A; Klipstein-Grobusch, Kerstin; Oladokun, Samuel; Welaga, Paul; Ansah, Patrick O; Hystad, Perry; Vermeulen, Roel; Oduro, Abraham R; Downward, George (Elsevier Limited, 2024-05)

INTRODUCTION: Environmental exposures, such as ambient air pollution and household fuel use affect health and under-5 mortality (U5M) but there is a paucity of data in the Global South. This study examined early-life ...
Primary Hypothyroidism in Childhood Cancer Survivors Treated With Radiation Therapy: A PENTEC Comprehensive Review

Milano, Michael T; Vargo, John A; Yorke, Ellen D; Ronckers, Cécile M; Kremer, Leontien C; Chafe, Susan M J; van Santen, Hanneke M; Marks, Lawrence B; Bentzen, Søren M; Constine, Louis S; Vogelius, Ivan R (Elsevier, 2024-06-01)

Purpose: From the Pediatric Normal Tissue Effects in the Clinic (PENTEC) initiative, a systematic review and meta-analysis of publications reporting on radiation dose-volume effects for risk of primary hypothyroidism after ...
Breast Hypoplasia and Decreased Lactation From Radiation Therapy in Survivors of Pediatric Malignancy: A PENTEC Comprehensive Review

Lo, Andrea C; Ronckers, Cecile; Aznar, Marianne C; Avanzo, Michele; van Dijk, Irma; Kremer, Leontien C M; Gagliardi, Giovanna; Howell, Rebecca M; Rancati, Tiziana; Constine, Louis S; Marcus, Karen J (Elsevier, 2024-06-01)

Purpose: Breast hypoplasia and impaired lactation are poorly studied sequelae of chest radiation therapy (RT) in children. The Pediatric Normal Tissue Effects in the Clinic female breast task force aimed to quantitate the ...
A dyadic perspective on parent-child dyadic coping in children with a chronic condition

van der Wal, Reine C.; Nijhof, Sanne L.; Leisten, Luca M.; van de Putte, Elise M.; van der Ent, Cornelis K.; Hindriks-Keegstra, Alinde W.; Bodenmann, Guy; Finkenauer, Catrin; Nap-van der Vlist, Merel M. (Elsevier, 2024-06)

Objective: In this study, we examined the extent to which parents and their children with a chronic condition communicate their stress to one another and whether stress communication is associated with different forms of ...
Direct Infusion Mass Spectrometry to Rapidly Map Metabolic Flux of Substrates Labeled with Stable Isotopes

Meijer, Nils W F; Zwakenberg, Susan; Gerrits, Johan; Westland, Denise; Ardisasmita, Arif I; Fuchs, Sabine A; Verhoeven-Duif, Nanda M; Jans, Judith J M; Zwartkruis, Fried J T (Multidisciplinary Digital Publishing Institute, 2024-04-25)

Direct infusion-high-resolution mass spectrometry (DI-HRMS) allows for rapid profiling of complex mixtures of metabolites in blood, cerebrospinal fluid, tissue samples and cultured cells. Here, we present a DI-HRMS method ...
One Chaperone to Rule Them All: Deciphering How Chromatin is Assembled During DNA Replication

Rouillon, Clément (Utrecht University, 2024-07-04)

Genomic DNA, which governs cellular life, resides within the nucleus of every human cell. Inside each nucleus lies approximately two meters of DNA, posing a significant challenge, akin to compacting 20 kilometers of thread ...
Continent catheterizable urinary channels: Lessons for lifelong urological care from a comparative analysis of very long-term complications and revision-free survival of three different types

Polm, Pepijn D; Christiaans, Coen H H; Dik, Pieter; Wyndaele, Michel I A; de Kort, Laetitia M O (John Wiley & Sons Inc., 2024-06)

INTRODUCTION: Continent catheterizable channels (CCC) provide an alternative route to the bladder in both pediatric and adult patients. This study compared very long-term complications and revision-free survival of three ...
Prognostic significance of MRI-detected extramural venous invasion according to grade and response to neo-adjuvant treatment in locally advanced rectal cancer A national cohort study after radiologic training and reassessment

the Dutch Snapshot Research Group (W.B. Saunders Ltd, 2024-06)

Background: Detection of grade 3–4 extra mural venous invasion (mrEMVI) on magnetic resonance imaging (MRI) is associated with an increased distant metastases (DM)-rate. This study aimed to determine the impact of different ...
Trends in incidence, treatment, and relative survival of colorectal cancer in the Netherlands between 2000 and 2021

Swartjes, Hidde; Sijtsma, Femke P.C.; Elferink, Marloes A.G.; van Erning, Felice N.; Moons, Leon M.G.; Verheul, Henk M.W.; Berbée, Maaike; Vissers, Pauline A.J.; de Wilt, Johannes H.W. (Elsevier Limited, 2024-07)

Background: The epidemiology of colorectal cancer (CRC) has changed rapidly over the years. The aim of this study was to assess the trends in incidence, treatment, and relative survival (RS) of patients diagnosed with CRC ...
A multi-institutional comparison of retrospective deformable dose accumulation for online adaptive magnetic resonance-guided radiotherapy

Murr, Martina; Bernchou, Uffe; Bubula-Rehm, Edyta; Ruschin, Mark; Sadeghi, Parisa; Voet, Peter; Winter, Jeff D.; Yang, Jinzhong; Younus, Eyesha; Zachiu, Cornel; Zhao, Yao; Zhong, Hualiang; Thorwarth, Daniela (Elsevier, 2024-04)

Background and Purpose: Application of different deformable dose accumulation (DDA) solutions makes institutional comparisons after online-adaptive magnetic resonance-guided radiotherapy (OA-MRgRT) challenging. The aim of ...
Assessing quality of hepato-pancreato-biliary surgery: nationwide benchmarking

for the Dutch Hepato Biliary Audit (DHBA), Dutch Pancreatic Cancer Audit (DPCA) and the Dutch Institute of Clinical Auditing (DICA) (John Wiley & Sons Inc., 2024-05-01)

Background: Clinical auditing is a powerful tool to evaluate and improve healthcare. Deviations from the expected quality of care are identified by benchmarking the results of individual hospitals using national averages. ...
Implementation and outcome of minimally invasive pancreatoduodenectomy in Europe: a registry-based retrospective study - a critical appraisal of the first 3 years of the E-MIPS registry

European Consortium on Minimally Invasive Pancreatic Surgery (E-MIPS) (Elsevier, 2024-04-01)

BACKGROUND: International multicenter audit-based studies focusing on the outcome of minimally invasive pancreatoduodenectomy (MIPD) are lacking. The European Registry for Minimally Invasive Pancreatic Surgery (E-MIPS) is ...
Robot-assisted versus laparoscopic pancreatoduodenectomy: a pan-European multicenter propensity-matched study

European Consortium on Minimally Invasive Pancreatic Surgery (E-MIPS) (Mosby Inc., 2024-06)

Background: The use of robot-assisted and laparoscopic pancreatoduodenectomy is increasing, yet large adjusted analyses that can be generalized internationally are lacking. This study aimed to compare outcomes after ...
Impact of Neoadjuvant Therapy for Pancreatic Cancer: Transatlantic Trend and Postoperative Outcomes Analysis

Global Audits on Pancreatic Surgery Group (GAPASURG) (2024-04-01)

BACKGROUND: The introduction of modern chemotherapy a decade ago has led to increased use of neoadjuvant therapy (NAT) in patients with pancreatic ductal adenocarcinoma (PDAC). A recent North American study demonstrated ...
Early experience with robotic pancreatoduodenectomy versus open pancreatoduodenectomy: nationwide propensity-score-matched analysis

de Graaf, Nine; Zwart, Maurice J.W.; van Hilst, Jony; van den Broek, Bram; Bonsing, Bert A.; Busch, Olivier R.; Coene, Peter Paul L.O.; Daams, Freek; van Dieren, Susan; van Eijck, Casper H.J.; Festen, Sebastiaan; de Hingh, Ignace H.J.T.; Lips, Daan J.; Luyer, Misha D.P.; Mieog, J. Sven D.; van Santvoort, Hjalmar C.; van der Schelling, George P.; Stommel, Martijn W.J.; de Wilde, Roeland F.; Molenaar, I. Quintus; Koerkamp, Bas Groot; Besselink, Marc G. (John Wiley & Sons Inc., 2024-02-01)

Background: Although robotic pancreatoduodenectomy has shown promising outcomes in experienced high-volume centres, it is unclear whether implementation on a nationwide scale is safe and beneficial. The aim of this study ...
Splanchnic vein thrombosis in necrotizing pancreatitis: a post-hoc analysis of a nationwide prospective cohort

for the Dutch Pancreatitis Study Group (John Wiley & Sons Inc., 2024-04)

Background: Treatment guidelines for splanchnic vein thrombosis in necrotizing pancreatitis are lacking due to insufficient data on the full clinical spectrum. Methods: We performed a post-hoc analysis of a nationwide ...
Adjuvant Nivolumab in Esophageal Cancer with Positive Resection Margins: A Premature Leap?

Goense, Lucas; van Hillegersberg, Richard (Springer New York, 2024-06)
Evolution of clinical nature, treatment and survival of locally recurrent rectal cancer: Comparative analysis of two national cross-sectional cohorts

van Geffen, E G M; Langhout, J M A; Hazen, S J A; Sluckin, T C; van Dieren, S; Beets, G L; Beets-Tan, R G H; Borstlap, W A A; Burger, J W A; Horsthuis, K; Intven, M P W; Aalbers, A G J; Havenga, K; Marinelli, A W K S; Melenhorst, J; Nederend, J; Peulen, H M U; Rutten, H J T; Schreurs, W H; Tuynman, J B; Verhoef, C; de Wilt, J H W; Marijnen, C A M; Tanis, P J; Kusters, M; On Behalf Of The Dutch Snapshot Research Group (Elsevier Limited, 2024-05)

BACKGROUND: In the Netherlands, use of neoadjuvant radiotherapy for rectal cancer declined after guideline revision in 2014. This decline is thought to affect the clinical nature and treatability of locally recurrent rectal ...
Molecular characteristics of carbapenemase-producing Enterobacterales in the Netherlands; results of the 2014–2018 national laboratory surveillance

Dutch CPE surveillance Study Group (Elsevier, 2020-10)

Objectives: Carbapenem resistance mediated by mobile genetic elements has emerged worldwide and has become a major public health threat. To gain insight into the molecular epidemiology of carbapenem resistance in The ...

Now showing items 7301-7320 of 40729