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Towards single-cell bioprinting: micropatterning tools for organ-on-chip development

Bosmans, Cécile; Ginés Rodriguez, Núria; Karperien, Marcel; Malda, Jos; Moreira Teixeira, Liliana; Levato, Riccardo; Leijten, Jeroen (Elsevier Limited, 2024-06)

Organs-on-chips (OoCs) hold promise to engineer progressively more human-relevant in vitro models for pharmaceutical purposes. Recent developments have delivered increasingly sophisticated designs, yet OoCs still lack in ...
Very long-term follow-up of Indiana Pouches proves durability

Polm, Pepijn D.; Wyndaele, Michel I.A.; de Kort, Laetitia M.O. (John Wiley & Sons Inc., 2024-06)

Introduction: An Indiana Pouch (IP) is a heterotopic, continent, urinary diversion from an ileocolonic segment. Numerous studies have investigated its long-term outcomes, albeit none extending beyond a 5-year follow-up ...
Immunotherapy for Gestational Trophoblastic Neoplasia: a new paradigm

Baas, Inge O; Westermann, Anneke M; You, Benoit; Bolze, Pierre-Adrien; Seckl, Michael; Ghorani, Ehsan (S. Karger AG, 2024)

Background: Immune checkpoint immunotherapy (CPI) targeting programmed cell death 1 (PD-1)/ligand (PD-L1) has been shown to be an effective treatment for gestational trophoblastic neoplasia (GTN). This includes those with ...
Impact of intraoperative imaging on decision-making during spine surgery: a survey among spine surgeons using simulated intraoperative images

Bindels, Bas J J; Hovenier, Renée; Groot, Olivier Q; Vincken, Koen L; Rongen, Jan J; Smits, Maarten L J; Verlaan, Jorrit-Jan (Springer-Verlag, 2024-05)

Purpose: To assess whether the intention to intraoperatively reposition pedicle screws differs when spine surgeons evaluate the same screws with 2D imaging or 3D imaging. Methods: In this online survey study, 21 spine ...
Overweight in Adolescence and Young Adulthood in Association with Adult Cerebrovascular Disease: The NFBC1966 Study

Mikkola, Ursula; Rissanen, Ina; Kivelä, Milja; Rusanen, Harri; Kajantie, Eero; Miettunen, Jouko; Paananen, Markus (Lippincott Williams & Wilkins, 2024-07-01)

BACKGROUND: Risk factors for cerebrovascular disease in adulthood are well known. However, research on individuals' risk factors throughout their life span has been limited. This prospective cohort study aims to determine ...
Mitochondrial Cardiomyopathies

Blank, AC; Breur, JMPJ; Fuchs, S.A.; Koop, K; Baas, AF (Springer International Publishing AG, 2020-01-01)

Primary mitochondrial diseases (PMD) are caused by mitochondrial dysfunction due to mutations in nuclear or mitochondrial DNA. Cardiac involvement is present in the majority of patients with cardiomyopathy, arrhythmias, ...
Hearing outcome after linear accelerator-based radiotherapy for vestibular schwannomas: A retrospective analysis of a single center

de Jel, Dominique Valérie Clarence; Smid, Ernst J.; van Doormaal, Tristan P.C.; Thomeer, Hans G.X.M. (Aves, 2021-09)

OBJECTIVE: To report our results on hearing preservation after linear accelerator (LINAC)-based stereotactic radiotherapy for vestibular schwan-nomas (VS) in a tertiary referral center. METHODS: All patients who presented ...
Aandacht voor Diversiteit en Inclusie in onze universitaire cultuur

van der Velden, Gisela; Dilaver, G (Utrecht University, 2022)

Ieder mens is uniek en heeft een eigen perspectief. Het hebben en respecteren van diverse perspectieven binnen de universitaire cultuur, het klaslokaal en het werkveld zal bijdragen aan betere oplossingen van maatschappelijke ...
Impact of the 2021 European Society for Cardiology prevention guideline’s stepwise approach for cardiovascular risk factor treatment in patients with established atherosclerotic cardiovascular disease

Holtrop, Joris; Bhatt, Deepak L; Ray, Kausik K; Mach, François; Smulders, Yvo M; Carballo, David; Steg, Philippe Gabriel; Visseren, Frank L J; Dorresteijn, Jannick A N (Oxford University Press, 2024-04-01)

Aims This study aimed to evaluate the stepwise approach for cardiovascular (CV) risk factor treatment as outlined by the European Society for Cardiology 2021 guidelines on CV disease (CVD) prevention in patients with ...
Understanding the matrix: collagen modifications in tumors and their implications for immunotherapy

Borst, Rowie; Meyaard, Linde; Pascoal Ramos, M. Ines (BioMed Central, 2024-04-24)

Tumors are highly complex and heterogenous ecosystems where malignant cells interact with healthy cells and the surrounding extracellular matrix (ECM). Solid tumors contain large ECM deposits that can constitute up to 60% ...
Quality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series

Cancer Cachexia Endpoints Working Group (Wiley-Blackwell, 2024-06)

The use of patient-reported outcomes (PROMs) of quality of life (QOL) is common in cachexia trials. Patients' self-report on health, functioning, wellbeing, and perceptions of care, represent important measures of efficacy. ...
Development of the respiratory tract microbiota in cystic fibrosis

de Koff, Emma M; de Winter - de Groot, KM; Bogaert, D (Lippincott Williams & Wilkins, 2016-11)

PURPOSE OF REVIEW: Progression of lung disease in cystic fibrosis (CF) is punctuated by Pseudomonas aeruginosa infection and recurrent pulmonary exacerbations, and is the major determinant of a patient's life expectancy. ...
Identi catie van micro-organismen met behulp van Matrix-Assisted Laser Desorption/Ionisation-Time Of Flight Mass Spectrometry (MALDI-TOF MS)

Kusters, JG; Van Drongelen, Adriaan M. (2015-01-15)

Binnen de medische microbiologie is er behoefte aan snelle, accurate en kosteneffectieve methoden voor het identificeren van micro-organismen. Tot voor kort vonden identificaties hoofdzakelijk plaats op basis van morfologische ...
COVID-19 disease in patients with chronic neutropenia: The experience from the European Network for Innovative Diagnosis and Treatment of Chronic Neutropenias

Spanoudakis, Michail; Yilmaz Karapinar, Deniz; Dale, David; Bolyard, Audrey Anna; Tran, Emily; Roganovic, Jelena; Bartels, Marije; Kapor, Suncica; Guardo, Daniela; Yacobovich, Joanne; Nilsson, Christer; Bezzerri, Valentino; Cipolli, Marco; Pegoraro, Anna; Aleksov, Emil; Guenova, Margarita; Dufour, Carlo; Fioredda, Francesca; Papadaki, Helen A.; Palmblad, Jan (Wiley-Blackwell, 2024-06)
Diagnostiek en behandeling van verworven schildklieraandoeningen

van Santen, HM; Hoorweg-Nijman, Gera (2018-06)
External Quality Assessment on Molecular Tumor Profiling with Circulating Tumor DNA-Based Methodologies Routinely Used in Clinical Pathology within the COIN Consortium

van der Leest, Paul; Rozendal, Pim; Hinrichs, John; van Noesel, Carel J M; Zwaenepoel, Karen; Deiman, Birgit; Huijsmans, Cornelis J J; van Eijk, Ronald; Speel, Ernst Jan M; van Haastert, Rick J; Ligtenberg, Marjolijn J L; van Schaik, Ron H N; Jansen, Maurice P H M; Dubbink, Hendrikus J; de Leng, Wendy W; Leers, Mathie P G; Tamminga, Menno; van den Broek, Daan; van Kempen, Léon C; Schuuring, Ed (Oxford University Press, 2024-05-01)

BACKGROUND: Identification of tumor-derived variants in circulating tumor DNA (ctDNA) has potential as a sensitive and reliable surrogate for tumor tissue-based routine diagnostic testing. However, variations in pre(analytical) ...
De Hielprik - 2. Erfelijke metabole ziekten

Wijburg, Frits A.; Visser, G (Stichting Biowetenschappen en Maatschappij, 2018-03-31)
BioMimics 3D Stent Graft System in Chronic Limb Threatening Ischaemia and Complex Femoropopliteal Lesions: The New Dimension in Complex Endovascular Interventions?

Teraa, Martin; von Allmen, Regula S (W.B. Saunders Ltd, 2024-06)
Longitudinal Fluctuations in Protein Concentrations and Higher-Order Structures in the Plasma Proteome of Kidney Failure Patients Subjected to a Kidney Transplant

Kalaidopoulou Nteak, Sofia; Völlmy, Franziska; Lukassen, Marie V.; van den Toorn, Henk; den Boer, Maurits A.; Bondt, Albert; van der Lans, Sjors P.A.; Haas, Pieter Jan; van Zuilen, Arjan D.; Rooijakkers, Suzan H.M.; Heck, Albert J.R. (American Chemical Society, 2024-06-07)

Using proteomics and complexome profiling, we evaluated in a year-long study longitudinal variations in the plasma proteome of kidney failure patients, prior to and after a kidney transplantation. The post-transplant period ...
Differential dynamics of TARC during JAK-inhibitor therapy compared to biological therapies targeting type 2 inflammation

Boesjes, Celeste M; Bakker, Daphne S; Knol, Edward F; de Graaf, Marlies; van Wijk, Femke; de Bruin-Weller, Marjolein S (Wiley-Blackwell, 2024-04)

Now showing items 6881-6900 of 40729