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UMC Repository: Recent submissions

  • In Vivo Prevention of Implant-Associated Infections Caused by Antibiotic-Resistant Bacteria through Biofunctionalization of Additively Manufactured Porous Titanium 
    van Hengel, Ingmar Aeneas Jan; van Dijk, Bruce; Modaresifar, Khashayar; Hooning van Duyvenbode, Johan Frederik Felix; Nurmohamed, Faisal Ruben Hamzah Aziz; Leeflang, Marius Alexander; Fluit, Adriaan Camille; Fratila-Apachitei, Lidy Elena; Apachitei, Iulian; Weinans, Harrie; Zadpoor, Amir Abbas (Multidisciplinary Digital Publishing Institute (MDPI), 2023-10)
    Additively manufactured (AM) porous titanium implants may have an increased risk of implant-associated infection (IAI) due to their huge internal surfaces. However, the same surface, when biofunctionalized, can be used to ...
  • Ideal cardiovascular health and cardiovascular related events: a systematic review and meta-analysis 
    Te Hoonte, Femke; Spronk, Merve; Sun, Qi; Wu, Kangrui; Fan, Shiqi; Wang, Ziyi; Bots, Michiel L; Van der Schouw, Yvonne T; Uijl, Alicia; Vernooij, Robin W M (Oxford University Press, 2024-06-01)
    Aims The aim of this study was to systematically review and quantitatively summarize the evidence on the association between Life Simple’s 7 (LS7) and multiple cardiovascular diseases (CVDs) and cardiometabolic diseases ...
  • Oxygen-consumption based quantification of chemogenetic H2O2 production in live human cells 
    den Toom, Wytze T.F.; van Soest, Daan M.K.; Polderman, Paulien E.; van Triest, Miranda H.; Bruurs, Lucas J.M.; De Henau, Sasha; Burgering, Boudewijn M.T.; Dansen, Tobias B. (Elsevier, 2023-09)
    Reactive Oxygen Species (ROS) in the form of H2O2 can act both as physiological signaling molecules as well as damaging agents, depending on their concentration and localization. The downstream biological effects of H2O2 ...
  • Reframing Communication about Fall Prevention Programs to Increase Older Adults' Intentions to Participate 
    van Scherpenseel, Meike C; van Veenendaal, Lidia J; Te Velde, Saskia J; Volk, Elise; Barten, Di-Janne J A; Veenhof, Cindy; Emmelot-Vonk, Marielle H; Ronteltap, Amber (Multidisciplinary Digital Publishing Institute (MDPI), 2024-06)
    INTRODUCTION: Falls and fall-related injuries in community-dwelling older adults are a growing global health concern. Despite effective exercise-based fall prevention programs (FPPs), low enrollment rates persist due to ...
  • Gene therapies, uncertainty, and decision-making: thinking about the last mile at the first step 
    Frederix, GW; ten Ham, RMT (Taylor and Francis Ltd., 2023-08)
  • Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum 
    Andrzejczyk, Karolina; Abou Kamar, Sabrina; van Ommen, Anne-Mar; Canto, Elisa Dal; Petersen, Teun B; Valstar, Gideon; Akkerhuis, K Martijn; Cramer, Maarten Jan; Umans, Victor; Rutten, Frans H; Teske, Arco; Boersma, Eric; Menken, Roxana; van Dalen, Bas M; Hofstra, Leonard; Verhaar, Marianne; Brugts, Jasper; Asselbergs, Folkert; den Ruijter, Hester; Kardys, Isabella (Nature Publishing Group, 2024-06-27)
    Circulating proteins may provide insights into the varying biological mechanisms involved in heart failure (HF) with preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF). We aimed to identify specific ...
  • Spin-pm: A consensus framework to evaluate the presence of spin in studies on prediction models 
    Andaur Navarro, Constanza L; Damen, Johanna Aa; Ghannad, Mona; Dhiman, Paula; van Smeden, Maarten; Reitsma, Johannes B; Collins, Gary S; Riley, Richard D; Moons, Karel Gm; Hooft, Lotty (Elsevier, 2024-06)
    Objectives: To develop a framework to identify and evaluate spin practices and its facilitators in studies on clinical prediction model regardless of the modeling technique. Study Design and Setting: We followed a three-phase ...
  • Clinical Outcomes of Integrase Strand Transfer Inhibitors Containing Antiretroviral Therapy in HIV-2: A Narrative Review 
    Boschloo, Wendy J.; van Welzen, Berend J. (Springer Healthcare, 2024-06)
    The human immunodeficiency virus type 2 (HIV-2) is a particular subtype of HIV, which is endemic in West Africa and is characterized by a more indolent course than HIV-1. As people living with HIV-2 (PWH-2) are at risk for ...
  • Ultra-Early and Short-Term Tranexamic Acid Treatment in Patients With Good- and Poor-Grade Aneurysmal Subarachnoid Hemorrhage 
    Tjerkstra, Maud A.; Post, René; Germans, Menno R.; Vergouwen, Mervyn D.I.; Jellema, Korne; Koot, Radboud W.; Kruyt, Nyika D.; Wolfs, Jasper F.C.; De Beer, Frits C.; Kieft, Hans H.; Nanda, Dharmin; Van Der Pol, Bram; Roks, Gerwin; De Beer, Frank; Reichman, Loes J.A.; Brouwers, Paul J.A.M.; Kwa, Vincent I.H.; Van Der Ree, Taco C.; Bienfait, Henri P.; Boogaarts, Hieronymus D.; Klijn, Catharina J.; Visser, Victoria; van den Berg, René; Coert, Bert A.; Horn, Janneke; Majoie, Charles B.L.M.; Rinkel, Gabriël J.E.; Roos, Yvo B.W.E.M.; Vandertop, W. Peter; Verbaan, Dagmar; ULTRA trial study group (Lippincott Williams & Wilkins, 2024-06-25)
    BACKGROUND AND OBJECTIVES: The results of the ULTRA trial showed that ultra-early and short-term treatment with tranexamic acid (TXA) does not improve clinical outcome after aneurysmal subarachnoid hemorrhage (aSAH). ...
  • Seizure Outcome After Intraoperative Electrocorticography-Tailored Epilepsy Surgery: A Systematic Review and Meta-Analysis 
    Guo, Jiaojiao; Wang, Ziyi; van 't Klooster, Maryse A.; Van Der Salm, Sandra M.; Leijten, Frans S.; Braun, Kees P.; Zijlmans, Maeike (Lippincott Williams & Wilkins, 2024-06-11)
    BACKGROUND AND OBJECTIVES: Tailoring epilepsy surgery using intraoperative electrocorticography (ioECoG) has been debated, and modest number of epilepsy surgery centers apply this diagnostic method. We assessed the current ...
  • Enhancing Cognitive Performance Prediction through White Matter Hyperintensity Connectivity Assessment: A Multicenter Lesion Network Mapping Analysis of 3,485 Memory Clinic Patients 
    Petersen, Marvin; Coenen, Mirthe; DeCarli, Charles; De Luca, Alberto; van der Lelij, Ewoud; Barkhof, Frederik; Benke, Thomas; Chen, Christopher P L H; Dal-Bianco, Peter; Dewenter, Anna; Duering, Marco; Enzinger, Christian; Ewers, Michael; Exalto, Lieza G; Fletcher, Evan F; Franzmeier, Nicolai; Hilal, Saima; Hofer, Edith; Koek, Huiberdina L; Maier, Andrea B; Maillard, Pauline M; McCreary, Cheryl R; Papma, Janne M; Pijnenburg, Yolande A L; Schmidt, Reinhold; Smith, Eric E; Steketee, Rebecca M E; van den Berg, Esther; van der Flier, Wiesje M; Venkatraghavan, Vikram; Venketasubramanian, Narayanaswamy; Vernooij, Meike W; Wolters, Frank J; Xu, Xin; Horn, Andreas; Patil, Kaustubh R; Eickhoff, Simon B; Thomalla, Götz; Biesbroek, J Matthijs; Biessels, Geert Jan; Cheng, Bastian; Alzheimer's Disease Neuroimaging Initiative (medRxiv, 2024-04-11)
    INTRODUCTION: White matter hyperintensities of presumed vascular origin (WMH) are associated with cognitive impairment and are a key imaging marker in evaluating cognitive health. However, WMH volume alone does not fully ...
  • Whole blood thiamine, intravenous thiamine supplementation and delirium occurrence in the intensive care unit: retrospective cohort analyses 
    Mumin, Muhammad A; McKenzie, Cathrine A; Page, Valerie J; Hadfield, Daniel; Aitken, Leanne M; Hanks, Fraser; Cunningham, Emma; Blackwood, Bronagh; Van Dellen, Edwin; Slooter, Arjen J C; Grocott, Michael P W; McAuley, Daniel F; Spronk, Peter E (Springer Netherlands, 2024-06)
    BACKGROUND: Thiamine di-phosphate is an essential cofactor in glucose metabolism, glutamate transformation and acetylcholinesterase activity, pathways associated with delirium occurrence. We hypothesised that a deficiency ...
  • High-dose individualized antithymocyte globulin with therapeutic drug monitoring in high-risk cord blood transplant 
    Admiraal, Rick; Versluijs, A Birgitta; Huitema, Alwin D R; Ebskamp, Lysette; Lacna, Amelia; de Kanter, C T Klaartje; Bierings, Marc B; Boelens, Jaap Jan; Lindemans, Caroline A; Nierkens, Stefan (Informa Healthcare, 2024-06)
    Background: Graft-versus-host disease (GvHD) and rejection are main limitations of cord blood transplantation (CBT), more so in patients with severe inflammation or previous rejections. While rigorous T-cell depletion with ...
  • Clinicopathological Factors as Predictors for Establishment of Patient Derived Head and Neck Squamous Cell Carcinoma Organoids 
    de Kort, W W B; Millen, R; Driehuis, E; Devriese, L A; van Es, R J J; Willems, S M (Humana Press, 2024-06-28)
    INTRODUCTION: Patient derived organoids (PDOs) are 3D in vitro models and have shown to better reflect patient and tumor heterogeneity than conventional 2D cell lines. To utilize PDOs in clinical settings and trials for ...
  • Evolution of European prostate cancer screening protocols and summary of ongoing trials 
    van Harten, Meike J; Roobol, Monique J; van Leeuwen, Pim J; Willemse, Peter-Paul M; van den Bergh, Roderick C N (Wiley-Blackwell, 2024-07)
    Population-based organised repeated screening for prostate cancer has been found to reduce disease-specific mortality, but with substantial overdiagnosis leading to overtreatment. Although only very few countries have ...
  • Effects of a Multicomponent Lipid Emulsion on Brain Volumes in Extremely Low Birth Weight Infants 
    Costa, Simonetta; Cocca, Carmen; D'Apolito, Gabriella; De Gisi, Antonietta; Fattore, Simona; Tataranno, Maria L; Benders, Manon; Pastorino, Roberta; Colosimo, Cesare; Vento, Giovanni (Thieme Medical Publishers, 2024-05)
    Objective  During the early weeks of life optimization of nutrition in extremely preterm infants presents a critical opportunity to attenuate the adverse neurological consequences of prematurity and potentially improve ...
  • Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology-Guidelines 2023-overview, and primary local imaging: how and where? 
    Noebauer-Huhmann, Iris-Melanie; Vanhoenacker, Filip M; Vilanova, Joan C; Tagliafico, Alberto S; Weber, Marc-André; Lalam, Radhesh K; Grieser, Thomas; Nikodinovska, Violeta Vasilevska; de Rooy, Jacky W J; Papakonstantinou, Olympia; Mccarthy, Catherine; Sconfienza, Luca Maria; Verstraete, Koenraad; Martel-Villagrán, José; Szomolanyi, Pavol; Lecouvet, Frédéric E; Afonso, Diana; Albtoush, Omar M; Aringhieri, Giacomo; Arkun, Remide; Aström, Gunnar; Bazzocchi, Alberto; Botchu, Rajesh; Breitenseher, Martin; Chaudhary, Snehansh; Dalili, Danoob; Davies, Mark; de Jonge, Milko C; Mete, Berna D; Fritz, Jan; Gielen, Jan L M A; Hide, Geoff; Isaac, Amanda; Ivanoski, Slavcho; Mansour, Ramy M; Muntaner-Gimbernat, Lorenzo; Navas, Ana; O Donnell, Paul; Örgüç, Şebnem; Rennie, Winston; Resano, Santiago; Robinson, Philip; Sanal, Hatice T; Ter Horst, Simone A J; van Langevelde, Kirsten; Wörtler, Klaus; Koelz, Marita; Panotopoulos, Joannis; Windhager, Reinhard; Bloem, Johannes L (Springer-Verlag, 2024-07)
    OBJECTIVES: Early, accurate diagnosis is crucial for the prognosis of patients with soft tissue sarcomas. To this end, standardization of imaging algorithms, technical requirements, and reporting is therefore a prerequisite. ...
  • Personal preferences for treatment and care during and after a First Episode Psychosis: A qualitative study 
    van der Heijden-Hobus, Inge M W; Rosema, Bram-Sieben; Vorstman, Jacob A S; Kas, Martien J H; Franke, Sigrid K; Boonstra, Nynke; Sommer, Iris E C (Wiley-Blackwell, 2024-06)
    AIM: A first episode of psychosis (FEP) is a stressful, often life-changing experience. Scarce information is available about personal preferences regarding their care needs during and after a FEP. Whereas a more thorough ...
  • Induction of Fenestrae in Human Induced Pluripotent Stem Cell-Derived Endothelial Cells for Disease Modeling 
    Meijer, Elana Marianne; van Dijk, Christian G M; Giles, Rachel; Gijsen, Karlijn; Chrifi, Ihsan; Verhaar, Marianne C; Cheng, Caroline (Mary Ann Liebert Inc., 2024-02-01)
    The endothelial linings of capillaries, such as those in the kidney and small intestines, possess fenestrae that facilitate fluid and exchange of small molecules. Alterations in the size and number of endothelial fenestrae ...
  • Bronchiectasis is associated with lower lung function in lung cancer screening participants 
    Kwee, Anastasia K.A.L.; Luijk, Bart; de Jong, Pim A.; Groen, Harry J.M.; Aerts, Joachim G.J.V.; Charbonnier, Jean Paul; Vliegenthart, Rozemarijn; Mohamed Hoesein, Firdaus A.A. (Springer-Verlag, 2024-06)
    Background and objective: Bronchiectasis is a frequent incidental finding on chest computed tomography (CT), but its relevance in lung cancer screening is not fully understood. We investigated the association between ...