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Now showing items 6641-6660 of 40729

Accelerated Bacille Calmette-Guérin reactions: More than meets the eye

Villanueva, Paola; Crawford, Nigel W.; Croda, Mariana Garcia; Croda, Julio; Dalcolmo, Margareth; Jardim, Bruno Araújo; Jardim, Tyane de Almeida Pinto; Marshall, Helen; Prat-Aymerich, Cristina; Sawka, Alice; Sharma, Ketaki; Troeman, Darren; Warris, Adilia; Wood, Nicholas; Messina, Nicole L.; Pittet, Laure F.; Curtis, Nigel (Elsevier, 2024-07-15)

An accelerated local injection site reaction following Bacille Calmette-Guérin (BCG) vaccination has been associated with underlying active tuberculosis (TB) in high TB-prevalence settings. The clinical significance of ...
Single-Cell Dissection of the Immune Response After Acute Myocardial Infarction

van Blokland, Irene V.; Oelen, Roy; Groot, Hilde E.; Benjamins, Jan Walter; Pekayvaz, Kami; Losert, Corinna; Knottenberg, Viktoria; Heinig, Matthias; Nicolai, Leo; Stark, Konstantin; van der Harst, Pim; Franke, Lude; van der Wijst, Monique G.P. (Lippincott Williams & Wilkins, 2024-06-01)

BACKGROUND: The immune system's role in ST-segment-elevated myocardial infarction (STEMI) remains poorly characterized but is an important driver of recurrent cardiovascular events. While anti-inflammatory drugs show promise ...
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy

Nollet, Edgar E.; Schuldt, Maike; Sequeira, Vasco; Binek, Aleksandra; Pham, Thang V.; Schoonvelde, Stephan A.C.; Jansen, Mark; Schomakers, Bauke V.; van Weeghel, Michel; Vaz, Fred M.; Houtkooper, Riekelt H.; Van Eyk, Jennifer E.; Jimenez, Connie R.; Michels, Michelle; Bedi, Kenneth C.; Margulies, Kenneth B.; dos Remedios, Cristobal G.; Kuster, Diederik W.D.; van der Velden, Jolanda (Lippincott Williams & Wilkins, 2024-06-01)

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is caused by sarcomere gene mutations (genotype-positive HCM) in ≈50% of patients and occurs in the absence of mutations (genotype-negative HCM) in the other half of patients. ...
Reliability parameters of the Timed 25-Foot-Walk (T25FW) in patients with Multiple Sclerosis: Lower walking speed is associated with greater Smallest Detectable Change

Oosterveer, Daniëlla M.; Wouda, Natasja C.; Volker, Gerard; van den Berg, Christel; Terluin, Berend; Hoitsma, Elske (Elsevier, 2024-08)

Background: Reliability parameters of clinical measures should be sufficient in order to adequately monitor disease course and evaluate treatment in patients with Multiple Sclerosis (MS). The aim of this study was to assess ...
Enhancing Prostate Cancer Detection Accuracy in Magnetic Resonance Imaging–targeted Prostate Biopsy: Optimizing the Number of Cores Taken

Zattoni, Fabio; Fasulo, Vittorio; Kasivisvanathan, Veeru; Kesch, Claudia; Marra, Giancarlo; Martini, Alberto; Falagario, Ugo; Soeterik, Timo; van den Bergh, Roderick; Rajwa, Pawel; Gandaglia, Giorgio; EAU-YAU Prostate Cancer Working Party (PCa-WP) (Elsevier, 2024-08)

Background and objective: The shift toward targeted biopsy (TBx) aims at enhancing prostate cancer (PCa) detection while reducing overdiagnosis of clinically insignificant disease. Despite the improved ability of TBx in ...
Inhibitor development according to concentrate after 50 exposure days in severe hemophilia: data from the European HAemophilia Safety Surveillance (EUHASS)

Fischer, Kathelijn; Lassila, Riitta; Peyvandi, Flora; Gatt, Alexander; Gouw, Samantha C.; Hollingsworth, Rob; Lambert, Thierry; Kaczmarek, Radek; Carbonero, Diana; Makris, Mike; European HAemophilia Safety Surveillance (EUHASS) participants (Elsevier, 2024-05)

Background: Patients with hemophilia have a life-long risk of developing neutralizing antibodies (inhibitors) against clotting factor concentrates. After the first 50 exposure days (EDs), ie, in previously treated patients ...
ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 2-care pathways, treatment, and follow-up

The Task Force for the management of COVID-19 of the European Society of Cardiology (Oxford University Press, 2022)

Aims: Since its emergence in early 2020, the novel severe acute respiratory syndrome coronavirus 2 causing coronavirus disease 2019 (COVID-19) has reached pandemic levels, and there have been repeated outbreaks across the ...
European Society of Cardiology guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 1-epidemiology, pathophysiology, and diagnosis

The Task Force for the management of COVID-19 of the European Society of Cardiology (Oxford University Press, 2022-03-14)

Aims:Since its emergence in early 2020, the novel severe acute respiratory syndrome coronavirus 2 causing coronavirus disease 2019 (COVID-19) has reached pandemic levels, and there have been repeated outbreaks across the ...
First-line Therapy for Immune Thrombocytopenia: Time for Change

Schutgens, Roger E.G. (Wolters Kluwer Health, 2022-10-22)
Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Kliemann, Nathalie; Ammar, Romain Ould; Biessy, Carine; Gicquiau, Audrey; Katzke, Verena; Kaaks, Rudolf; Tjønneland, Anne; Olsen, Anja; Sánchez, Maria Jose; Crous-Bou, Marta; Pasanisi, Fabrizio; Tin, Sandar Tin; Perez-Cornago, Aurora; Aune, Dagfinn; Christakoudi, Sofia; Heath, Alicia K.; Colorado-Yohar, Sandra M.; Grioni, Sara; Skeie, Guri; Sartor, Hanna; Idahl, Annika; Rylander, Charlotta; May, Anne M.; Weiderpass, Elisabete; Freisling, Heinz; Playdon, Mary C.; Rinaldi, Sabina; Murphy, Neil; Huybrechts, Inge; Dossus, Laure; Gunter, Marc J. (American Association for Cancer Research Inc., 2022-07)

Background: Obesity is a risk factor for endometrial cancer but whether metabolic dysfunction is associated with endometrial cancer independent of body size is not known. Methods: The association of metabolically defined ...
A Retrospective Medical Record Review to Describe Health Status and Cardiovascular Disease Risk Factors of Bus Drivers in South Africa

Aitken, Susan C.; Lalla-Edward, Samanta T.; Kummerow, Maren; Tenzer, Stan; Harris, Bernice N.; Venter, W. D.Francois; Vos, Alinda G. (Multidisciplinary Digital Publishing Institute (MDPI), 2022-12)

Cardiovascular disease (CVD) is the leading cause of death globally. The occupational challenges of bus drivers may increase their risk of CVD, including developing obesity, hypertension, and diabetes. We evaluated the ...
Characteristics of pregnant women with diabetes using injectable glucose-lowering drugs in the EVOLVE study

Mathiesen, Elisabeth R.; Ali, Norsiah; Anastasiou, Eleni; Cypryk, Katarzyna; de Valk, Harold W.; Dores, Jorge M.; Dunne, Fidelma P.; Ekelund, Magnus; Durán García, Santiago; Hanaire, Hélène; Husemoen, Lise Lotte N.; Ivanisevic, Marina; Kempe, Hans Peter; Nordsborg, Rikke B.; McCance, David R. (Informa Healthcare, 2022-12)

Aims: To examine clinical parameters, glycemic control, folic acid supplementation, and the presence of other chronic diseases during early pregnancy in the EVOLVE study population (women with pre-existing diabetes treated ...
T cells, more than antibodies, may prevent symptoms developing from respiratory syncytial virus infections in older adults

Salaun, Bruno; De Smedt, Jonathan; Vernhes, Charlotte; Moureau, Annick; Öner, Deniz; Bastian, Arangassery Rosemary; Janssens, Michel; Balla-Jhagjhoorsingh, Sunita; Aerssens, Jeroen; Lambert, Christophe; Coenen, Samuel; Butler, Christopher C; Drysdale, Simon B; Wildenbeest, Joanne G; Pollard, Andrew J; Openshaw, Peter J M; Bont, Louis (Frontiers Media S. A., 2023-10-13)

INTRODUCTION: The immune mechanisms supporting partial protection from reinfection and disease by the respiratory syncytial virus (RSV) have not been fully characterized. In older adults, symptoms are typically mild but ...
Single-cell immune profiling reveals markers of emergency myelopoiesis that distinguish severe from mild respiratory syncytial virus disease in infants

RESCEU Investigators (Springer-Verlag, 2023-12)

Whereas most infants infected with respiratory syncytial virus (RSV) show no or only mild symptoms, an estimated 3 million children under five are hospitalized annually due to RSV disease. This study aimed to investigate ...
Animal Models for Studying Protein-Bound Uremic Toxin Removal—A Systematic Review

Ahmed, Sabbir; de Vries, Joost C.; Lu, Jingyi; Stuart, Milan H.Verrijn; Mihăilă, Silvia M.; Vernooij, Robin W.M.; Masereeuw, Rosalinde; Gerritsen, Karin G.F. (Multidisciplinary Digital Publishing Institute (MDPI), 2023-09)

Protein-bound uremic toxins (PBUTs) are associated with the progression of chronic kidney disease (CKD) and its associated morbidity and mortality. The conventional dialysis techniques are unable to efficiently remove PBUTs ...
Performance of the 2016 ACR-EULAR myositis response criteria in juvenile dermatomyositis therapeutic trials and consensus profiles

Kim, Hanna; Saygin, Didem; Douglas, Christian; Wilkerson, Jesse; Erman, Brian; Pistorio, Angela; McGrath, John A.; Reed, Ann M.; Oddis, Chester V.; Bracaglia, Claudia; Van Royen-Kerkhof, Annet; Bica, Blanca; Dolezalova, Pavla; Ferriani, Virginia P.L.; Flato, Berit; Bernard-Medina, Ana G.; Herlin, Troels; Miller, Frederick W.; Vencovsky, Jiri; Ruperto, Nicolino; Aggarwal, Rohit; Rider, Lisa G.; Pinal-Fernandez, Iago; Kim, Susan; Ascherman, Dana; Schiffenbauer, Adam (Oxford University Press, 2023-11-01)

Objectives: The 2016 ACR-EULAR Response Criteria for JDM was developed as a composite measure with differential weights of six core set measures (CSMs) to calculate a Total Improvement Score (TIS). We assessed the contribution ...
Maternal diet and human milk composition: an updated systematic review

Petersohn, Inga; Hellinga, Anneke H; van Lee, Linde; Keukens, Nicole; Bont, Louis; Hettinga, Kasper A; Feskens, Edith J M; Brouwer-Brolsma, Elske M (Frontiers Media S. A., 2023-01-24)

CONTEXT: Exclusive breastfeeding for 6 months after birth provides infants with the best start for life. A review by Bravi et al. summarized the importance of maternal diet as a determinant of human milk composition based ...
Different clinical features in Malawian outpatients presenting with COVID-19 prior to and during Omicron variant dominance: A prospective observational study

Chibwana, Marah G.; Thole, Herbert W.; Anscombe, Cat; Ashton, Philip M.; Green, Edward; Barnes, Kayla G.; Cornick, Jen; Turner, Ann; Witte, Desiree; Nthala, Sharon; Thom, Chikondi; Kanyandula, Felistas; Ainani, Anna; Mtike, Natasha; Tambala, Hope; N'goma, Veronica; Mwafulirwa, Dorah; Asima, Erick; Morton, Ben; Gmeiner, Markus; Gundah, Zaziwe; Kawalazira, Gift; French, Neil; Feasey, Nicholas; Heyderman, Robert S.; Swarthout, Todd D.; Jambo, Kondwani C. (Public Library of Science, 2023-03-08)

The SARS-CoV-2 Omicron variant has resulted in a high number of cases, but a relatively low incidence of severe disease and deaths, compared to the pre-Omicron variants. Therefore, we assessed the differences in symptom ...
Prophylactic Medication for the Prevention of Endoscopic Recurrence in Crohn's Disease: A Prospective Study Based on Clinical Risk Stratification

Arkenbosch, Jeanine H.C.; Beelen, Evelien M.J.; Dijkstra, Gerard; Romberg-Camps, Mariëlle; Duijvestein, Marjolijn; Hoentjen, Frank; Van Der Marel, Sander; Maljaars, P. W.Jeroen; Jansen, Sita; De Boer, Nanne K.H.; West, Rachel L.; Horjus, Carmen S.; Stassen, Laurents P.S.; Van Schaik, Fiona D.M.; Van Ruler, Oddeke; Jharap, Bindia J.H.; Visschedijk, Marijn; Janssen, Alfred; Erler, Nicole S.; Doukas, Michail; Ooms, Ariadne H.A.G.; Kats-Ugurlu, Gursah; Van Der Woude, Christien Janneke; De Vries, Annemarie C. (Elsevier, 2023-02-01)

Background: To prevent recurrence after ileocolonic resection [ICR] in Crohn's disease [CD], postoperative prophylaxis based on risk stratification is recommended in international guidelines. This study aimed to evaluate ...
Efficient organisation of the contralateral hemisphere connectome is associated with improvement in intelligence quotient after paediatric epilepsy surgery

Woodfield, Julie; Braun, Kees P.J.; van Schooneveld, Monique M.J.; Bastin, Mark E.; Chin, Richard F.M. (Academic Press Inc., 2023-12)

Objective: Aims of epilepsy surgery in childhood include optimising seizure control and facilitating cognitive development. Predicting which children will improve cognitively is challenging. We investigated the association ...

Now showing items 6641-6660 of 40729