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UMC Repository: Recent submissions

  • Plasma viscosity, immunoglobulins and risk of cardiovascular disease and mortality: new data and meta-analyses 
    Lowe, Gordon D.O.; Harris, Katie; Koenig, Wolfgang; Ben-Shlomo, Yoav; Thorand, Barbara; Peters, Annette; Meisinger, Christa; Imhof, Armin; Tunstall-Pedoe, Hugh; Peters, Sanne A.E.; Woodward, Mark (BMJ Publishing Group, 2024-06-01)
    Aims Associations of plasma viscosity and plasma Ig levels (a determinant of viscosity) with incident coronary heart disease (CHD) events; and with CHD, cardiovascular disease (CVD: CHD and stroke) and all-cause mortalities. ...
  • Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers 
    Boen, Rune; Kaufmann, Tobias; van der Meer, Dennis; Frei, Oleksandr; Agartz, Ingrid; Ames, David; Andersson, Micael; Armstrong, Nicola J.; Artiges, Eric; Atkins, Joshua R.; Bauer, Jochen; Benedetti, Francesco; Boomsma, Dorret I.; Brodaty, Henry; Brosch, Katharina; Buckner, Randy L.; Cairns, Murray J.; Calhoun, Vince; Caspers, Svenja; Cichon, Sven; Corvin, Aiden P.; Crespo-Facorro, Benedicto; Dannlowski, Udo; David, Friederike S.; de Geus, Eco J.C.; de Zubicaray, Greig I.; Desrivières, Sylvane; Doherty, Joanne L.; Donohoe, Gary; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fisher, Simon E.; Forstner, Andreas J.; Fortaner-Uyà, Lidia; Frouin, Vincent; Fukunaga, Masaki; Ge, Tian; Glahn, David C.; Goltermann, Janik; Grabe, Hans J.; Green, Melissa J.; Groenewold, Nynke A.; Grotegerd, Dominik; Grøntvedt, Gøril Rolfseng; Hahn, Tim; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Ophoff, Roel A.; van Haren, Neeltje E.M.; ENIGMA-CNV Working Group (Elsevier, 2024-01-15)
    Background: Carriers of the 1q21.1 distal and 15q11.2 BP1-BP2 copy number variants exhibit regional and global brain differences compared with noncarriers. However, interpreting regional differences is challenging if a ...
  • The Use of MR-Guided Radiation Therapy for Pancreatic Cancer 
    Daamen, Lois A.; Parikh, Parag J.; Hall, William A. (W.B. Saunders, 2024-01)
    The introduction of online adaptive magnetic resonance (MR)-guided radiation therapy (RT) has enabled safe treatment of pancreatic cancer with ablative doses. The aim of this review is to provide a comprehensive overview ...
  • Systematic review of the effectiveness of innovative, gamified interventions for cognitive training in paediatric acquired brain injury 
    van de Wouw, C. L.; Visser, M.; Gorter, J. W.; Huygelier, H.; Nijboer, T. C.W. (Taylor and Francis Ltd., 2024)
    Effectiveness of innovative, gamified interventions (i.e., Augmented Reality, Computer-Based Cognitive Retraining [CBCR], and Virtual Reality [VR] in conjunction with a Serious Game) for cognitive training in paediatric ...
  • Dealing with concomitant coronary artery disease in TAVI patients—should we treat it all in one go? 
    Aarts, Hugo M.; Delewi, Ronak; Claessen, Bimmer E.P.M. (Taylor and Francis Ltd., 2024)
  • Efficacy and safety of ligelizumab in adults and adolescents with chronic spontaneous urticaria: results of two phase 3 randomised controlled trials 
    Maurer, Marcus; Ensina, Luis Felipe; Gimenez-Arnau, Ana Maria; Sussman, Gordon; Hide, Michihiro; Saini, Sarbjit; Grattan, Clive; Fomina, Daria; Rigopoulos, Dimitrios; Berard, Frederic; Canonica, Giorgio Walter; Rockmann, Heike; Irani, Carla; Szepietowski, Jacek C.; Leflein, Jeffrey; Bernstein, Jonathan A.; Peter, Jonny G.; Kulthanan, Kanokvalai; Godse, Kiran; Ardusso, Ledit; Ukhanova, Olga; Staubach, Petra; Sinclair, Rodney; Gogate, Shaila; Thomsen, Simon Francis; Tanus, Tonny; Ye, Young Min; Burciu, Alis; Barve, Avantika; Modi, Darshna; Scosyrev, Emil; Hua, Eva; Letzelter, Kerstin; Varanasi, Vineeth; Patekar, Manmath; Severin, Thomas; Rosana, Agondi; Ahmed, Al Waily; Fabio, Almerigogna; Miguel Angel Tejedor, Alonso; Alfred, Ammoury; Eng Kim, Anne Goh; Robert, Anolik; Ledit, Ardusso; Petr, Arenberger; Nandini, A. S.; Mohammad, Asefi; Natalia, Astafieva; Anil, Badhwar; Esther Serra, Baldrich; PEARL-1 and PEARL-2 trial investigators (Elsevier, 2024-01-13)
    Background: Many patients with chronic spontaneous urticaria (CSU) do not achieve complete control of their symptoms with current available treatments. In a dose-finding phase 2b study, ligelizumab improved urticaria ...
  • Prevention of infections and fever to improve outcome in older patients with acute stroke (PRECIOUS): a randomised, open, phase III, multifactorial, clinical trial with blinded outcome assessment 
    de Jonge, Jeroen C.; Sluis, Wouter M.; Reinink, Hendrik; Bath, Philip M.; Woodhouse, Lisa J.; Zweedijk, Berber; van de Beek, Diederik; Aamodt, Anne Hege; Alpers, Iris; Ciccone, Alfonso; Csiba, Laszlo; Demotes, Jacques; Kõrv, Janika; Kurkowska-Jastrzebska, Iwona; Dawson, Jesse; Macleod, Malcolm R.; Ntaios, George; Poli, Sven; Milionis, Haralampos; Ricci, Stefano; Cenciarelli, Silvia; Candelaresi, Paolo; de Bruijn, Sebastiaan FTM; Pathansali, Rohan; Krishnan, Kailash; Clarke, Brian; Thomalla, Götz; van der Worp, H. Bart; Kwa, Vincent IH; Müller, Susanne; Protogerou, Athanasios D.; the PRECIOUS investigators (Elsevier, 2024-01)
    Background: Infections and fever after stroke are associated with poor functional outcome or death. We assessed whether prophylactic treatment with anti-emetic, antibiotic, or antipyretic medication would improve functional ...
  • The views of parents of children with cancer and pediatric physical therapists on a network for continuity and optimal quality of care for children with cancer: KinderOncoNet 
    Kleinlugtenbelt, L. B.; Tissing, W. J.E.; Solkema, W. J.M.Plieger van; van der Torre, P.; Kollen, W. J.W.; Gorter, J. W. (Springer-Verlag, 2024-01)
    Purpose: Children with cancer require specific therapeutic guidance. Parents prefer physical therapy close to home, while pediatric physical therapists (PPTs) working in the community may lack specific knowledge. The aim ...
  • Plasma proteomic analysis on neuropathic pain in idiopathic peripheral neuropathy patients 
    van Doormaal, Perry T.C.; Thomas, Simone; Ajroud-Driss, Senda; Cole, Robert N.; DeVine, Lauren R.; Dimachkie, Mazen M.; Geisler, Stefanie; Freeman, Roy; Simpson, David M.; Singleton, J. Robinson; Smith, A. Gordon; Stino, Amro; Höke, Ahmet (Wiley-Blackwell, 2024-03)
    Background and Aims: Why only half of the idiopathic peripheral neuropathy (IPN) patients develop neuropathic pain remains unknown. By conducting a proteomics analysis on IPN patients, we aimed to discover proteins and new ...
  • MRI in patients with a cerebral aneurysm clip; review of the literature and incident databases and recommendations for the Netherlands 
    Hofman, Mark B.M.; Lavini, Cristina; van der Zwan, Albert; van Pul, Carola; Muller, Sara H.; Stam, Mette K.; van der Graaf, Marinette; Kloeze, Carla; van Nierop, Bastiaan J.; Kappert, Peter; Kuijer, Joost P.A. (Associazione Italiana di Fisica Medica, 2024-01)
    Background: In the past ferromagnetic cerebral aneurysm clips that are contraindicated for Magnetic Resonance Imaging (MRI) have been implanted. However, the specific clip model is often unknown for older clips, which poses ...
  • Non-Neoplastic and Neoplastic Pathology of the Pancreas 
    Brosens, Lodewijk A.A.; Mino-Kenudson, Mari; Wood, Laura D. (Elsevier, 2022-01-01)
    The pancreas can be involved by a variety of developmental, inflammatory and neoplastic disorders. In contrast to the tubal gut, the spectrum of pancreatic neoplasms is broad and includes both cystic and solid tumors. ...
  • Neurodevelopmental outcome at 5.5 years in Dutch preterm infants born at 24–26 weeks’ gestational age: the EPI-DAF study 
    van Beek, Pauline E.; Rijken, Monique; Broeders, Lisa; ter Horst, Hendrik J.; Koopman-Esseboom, Corine; de Kort, Ellen; Laarman, A. R.C.; de Tollenaer, S. M.Mulder; Steiner, Katerina; Swarte, Renate M.C.; van Westering-Kroon, Elke; Oei, Guid; Leemhuis, Aleid G.; Andriessen, Peter (BMJ Publishing Group, 2024-05-01)
    Objective After lowering the Dutch threshold for active treatment from 25 to 24 completed weeks’ gestation, survival to discharge increased by 10% in extremely preterm live born infants. Now that this guideline has been ...
  • Bridging the gap between scientific discoveries and clinical application at the Utrecht Science Park 
    Peperzak, Victor; Coquet, Jonathan M. (John Wiley & Sons Inc., 2024-04)
    Associate Professor Victor Peperzak from the University Medical Center (UMC) Utrecht in the Netherlands discusses the opportunities and challenges of building a research group in the Netherlands. Victor highlights the ...
  • Preservation of human heart valves for replacement in children with heart valve disease: past, present and future 
    Peters, M. C.; Kruithof, B. P.T.; Bouten, C. V.C.; Voets, I. K.; van den Bogaerdt, A.; Goumans, M. J.; van Wijk, A. (Springer Netherlands, 2024-03)
    Valvular heart disease affects 30% of the new-borns with congenital heart disease. Valve replacement of semilunar valves by mechanical, bioprosthetic or donor allograft valves is the main treatment approach. However, none ...
  • Psychological impact of additional findings detected by genome-wide Non-Invasive Prenatal Testing (NIPT): TRIDENT-2 study 
    Bakkeren, Iris M.; Henneman, Lidewij; van Vliet-Lachotzki, Elsbeth H.; Martin, Linda; Gitsels-van der Wal, Janneke T.; Polak, Marike G.; Bekker, Mireille N.; Galjaard, Robert Jan H. (Springer Nature, 2024-03)
    In the Netherlands, genome-wide non-invasive prenatal testing (NIPT) is offered to all pregnant women as part of the nationwide TRIDENT-2 study. Findings other than trisomy 21, 18, or 13, which are called “additional ...
  • Reproductive outcomes and reproductive health care utilization among male survivors of childhood cancer: A DCCSS-LATER study 
    Claessens, Joyce J.M.; Penson, Adriaan; Bronkhorst, Ewald M.; Kremer, Leontien C.M.; van Dulmen-den Broeder, Eline; van der Heiden-van der Loo, Margriet; Tissing, Wim J.E.; van der Pal, Helena J.H.; Blijlevens, Nicole M.A.; van den Heuvel-Eibrink, Marry M.; Versluys, A. Birgitta; Bresters, Dorine; Ronckers, Cécile M.; Walraven, Iris; Beerendonk, Catharina C.M.; Loonen, Jacqueline J. (John Wiley & Sons Inc., 2024-03-15)
    Background: Treatment-related gonadal dysfunction leading to fertility problems is a frequently encountered late effect in childhood cancer survivors (CCSs). This study evaluated reproductive outcomes and reproductive ...
  • Effects of Bumetanide on Neurocognitive Functioning in Children with Autism Spectrum Disorder: Secondary Analysis of a Randomized Placebo-Controlled Trial 
    van Andel, Dorinde M.; Sprengers, Jan J.; Königs, Marsh; de Jonge, Maretha V.; Bruining, Hilgo (Springer New York, 2024-03)
    We present the secondary-analysis of neurocognitive tests in the ‘Bumetanide in Autism Medication and Biomarker’ (BAMBI;EUDRA-CT-2014-001560-35) study, a randomized double-blind placebo-controlled (1:1) trial testing ...
  • The cortisol switch between vulnerability and resilience 
    de Kloet, E. Ronald; Joëls, Marian (Springer Nature, 2024-01)
    In concert with neuropeptides and transmitters, the end products of the hypothalamus-pituitary-adrenal (HPA) axis, the glucocorticoid hormones cortisol and corticosterone (CORT), promote resilience: i.e., the ability to ...
  • Systematic Review and Meta-Analyses of Word Production Abilities in Dysfunction of the Basal Ganglia: Stroke, Small Vessel Disease, Parkinson’s Disease, and Huntington’s Disease 
    Camerino, Ileana; Ferreira, João; Vonk, Jet M.; Kessels, Roy P.C.; de Leeuw, Frank Erik; Roelofs, Ardi; Copland, David; Piai, Vitória (Springer New York, 2024-03)
    Clinical populations with basal ganglia pathologies may present with language production impairments, which are often described in combination with comprehension measures or attributed to motor, memory, or processing-speed ...
  • An international, multispecialty, expert-based Delphi Consensus document on controversial issues in the management of patients with asymptomatic and symptomatic carotid stenosis 
    Paraskevas, Kosmas I.; Mikhailidis, Dimitri P.; Ringleb, Peter Arthur; Brown, Martin M.; Dardik, Alan; Poredos, Pavel; Gray, William A.; Nicolaides, Andrew N.; Lal, Brajesh K.; Mansilha, Armando; Antignani, Pier Luigi; de Borst, Gert J.; Cambria, Richard P.; Loftus, Ian M.; Lavie, Carl J.; Blinc, Ales; Lyden, Sean P.; Matsumura, Jon S.; Jezovnik, Mateja K.; Bacharach, J. Michael; Meschia, James F.; Clair, Daniel G.; Zeebregts, Clark J.; Lanza, Gaetano; Capoccia, Laura; Spinelli, Francesco; Liapis, Christos D.; Jawien, Arkadiusz; Parikh, Sahil A.; Svetlikov, Alexei; Menyhei, Gabor; Davies, Alun H.; Musialek, Piotr; Roubin, Gary; Stilo, Francesco; Sultan, Sherif; Proczka, Robert M.; Faggioli, Gianluca; Geroulakos, George; Fernandes e Fernandes, Jose; Ricco, Jean Baptiste; Saba, Luca; Secemsky, Eric A.; Pini, Rodolfo; Myrcha, Piotr; Rundek, Tatjana; Martinelli, Ombretta; Kakkos, Stavros K.; Sachar, Ravish; Goudot, Guillaume; Schlachetzki, Felix; Lavenson, George S.; Ricci, Stefano; Topakian, Raffi; Millon, Antoine; Di Lazzaro, Vincenzo; Silvestrini, Mauro; Chaturvedi, Seemant; Eckstein, Hans Henning; Gloviczki, Peter; White, Christopher J. (Mosby Inc., 2024-02)
    Objective: Despite the publication of various national/international guidelines, several questions concerning the management of patients with asymptomatic (AsxCS) and symptomatic (SxCS) carotid stenosis remain unanswered. ...